Health-improving running loads are an effective means of improving the functions of the cardiovascular system. The study of the adaptive reactions of the cardiovascular system in women of different somatotypes under the influence of health- improving running classes allows to reveal the dynamics of the main indicators that determine the physical health of a person and to establish their somatotypological features. 80 women in the the first period of mature age (25-35 years old), who had not played sports before, took part in the study. Training sessions according to the health-improving running program were held 3 times a week. The basis of the program was running loads in the aerobic mode of energy supply, which were performed in a uniform continuous method. Dosing of running loads was carried out according to energy consumption. Heart rate was measured in a state of relative muscle rest. Blood pressure after dosed loads of different power was measured during the PWC170 test. In women aged 25-35, exercise to the health-improving running program caused a 2.2% decrease in heart rate at rest and a 2.1% decrease in systolic blood pressure after a dosed cycle ergometric exercise with a power of 1 W·kg. Among women of different somatotypes, a probable decrease in heart rate was found in representatives of the endomorphic somatotype. It has been established that health-improving running classes causes positive changes in the function of the cardiovascular system in women aged 25-35. Women of different somatotypes have different adaptive reactions of the cardiovascular system to health-improving running classes. Statistically confirmed changes were found only in representatives of the endomorphic somatotype.