<h3>Objective:</h3> To describe the work of a group of neurologists who have partnered with non-governmental organizations including Brother’s Brother Foundation (BBF) to provide (1) crisis relief and (2) sustainable support for Ukrainian neurology patients during the Russian invasion. <h3>Background:</h3> In the days following the Russian invasion of Ukraine, war and displacement quickly created many unanticipated needs. This included access to anti-seizure medications, placing estimated 250,000 of people with epilepsy at risk for serious injury and death. Dr. Olha Tychivska shared the challenges in obtaining medication for her patients with her North American neurology colleagues. <h3>Design/Methods:</h3> Utilizing social media and professional connections to catalyze rapid relief efforts, a small group of neurology providers from across the country joined forces to support Ukrainian neurology patients. A partnership with BBF and other non-profit organizations allowed this group to fundraise, procure, and safely deliver neurology medications to Ukraine, as Ukrainian neurologists directed needs and ascertained ethical use of medications and supplies. As the collaboration evolved, new needs for patients with neurologic injury surfaced, including traumatic brain injury and limb amputation. <h3>Results:</h3> Over 450,000 dollars have been raised and donated to date, with minimal overhead cost, towards neurology efforts. These include anti-seizure medications and equipment (EEG machine, VNS tablet/wand, and neurorehabilitation equipment). Additionally, a seizure resource guide was created, translated, and widely distributed. <h3>Conclusions:</h3> Grassroot movements can serve as catalysts for aid, as their dynamic model can address local needs in an effective and timely manner. We hope that this effort will serve as a roadmap for future efforts, and as a model of how neurologists can respond during future humanitarian crises to serve vulnerable patients. <b>Disclosure:</b> The institution of Dr. BriscoeAbath has received research support from Boston Children’s Hospital. Dr. BriscoeAbath has a non-compensated relationship as a Board of Trustees Member with Brother’s Brother Foundation that is relevant to AAN interests or activities. Dr. Tychkivska has nothing to disclose. Dr. Hadjinicolaou has nothing to disclose. Dr. Minster has nothing to disclose. Dr. Anselm has nothing to disclose. Ms. Friedman has nothing to disclose. Dr. Ivaniuk has nothing to disclose. Dr. Wirrell has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Dr. Wirrell has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biomarin. Dr. Wirrell has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Encoded. Dr. Wirrell has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Amicus. Dr. Wirrell has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Neurocrine. Dr. Wirrell has received publishing royalties from a publication relating to health care. Dr. Sharinn has nothing to disclose. The institution of Dr. Paciorkowski has received research support from University of Rochester. Dr. Snyder has nothing to disclose. Mike Corcoran has nothing to disclose. Mr. Stone has nothing to disclose. Mr. Samad has received personal compensation for serving as an employee of Brother’s Brother Foundation. Dr. Kielian has nothing to disclose. Dr. Faktorovich has a non-compensated relationship as a Board of Directors with Brother’s Brother Foundation that is relevant to AAN interests or activities.