Inspired by the advantage of unconventional photon blockade (UCPB), we propose a simple cavity-driven quantum electrodynamics model composed of a single two-level atom embedded in an asymmetrical Fabry-Perot cavity. We derive the necessary matching conditions of frequency and intensity required for unconventional photon blockade. In the asymmetric cavity, the optimal atom-cavity coupling strength to get UCPB is related to the driving direction, which causes the equal-time second-order correlation function ${g}^{(2)}(0)$ of the cavity field depending on the driving direction, too. Due to the direction dependent effect, the output photons can be bunched in one direction incident while they are antibunched in the opposite direction incident, which is the so-called nonreciprocal UCPB (NUCPB). A giant NUCPB can be obtained under the appropriate parameter regime, where the output photons are fully antibunching in the opposite driving case. Our findings show a prospective path to producing giant quantum nonreciprocity.