The Epistemic Competence of the Researcher is a critical success factor for ethical, rigorous, and creative research performance, but it requires a deep epistemological and methodological mastery, however, the current scientific literature has not yet achieved a conceptual arrangement, that allows researchers and educators to have a comprehensive theoretical framework for a holistic understanding of this competence. The objective of this study was to build a comprehensive theory on the epistemic competence of the researcher. A qualitative approach was used, deploying an open interview and the grounded theory method. Ten experts in social science didactics from 7 Latin American universities and 3 Spanish universities participated. The interviews were processed manually and with the support of ATLAS.TI software, finding 23 emerging categories that were contrasted with the results of a term co-occurrence network of 6081 studies imported from Scopus. From the cross-check of empirical and theoretical results, the following concepts were selected to coincide. Finally, the theoretical framework established was made up of the following concepts: 1.- knowledge building and conceptual change, 2.- epistemological beliefs, 3.- concept mapping and knowledge creation, 4.- conceptual understanding, 5.- conceptual framework, 6.- concept formation, 7.- epistemic beliefs, 8.- science education (learning science and science teaching) 9.- cognitive complexity, 10.- personal epistemology, 11.- virtue epistemology, 12.- formal logic, 13.- epistemic cognition, 14.- nature of science, 15.- epistemic emotions. A proposal for teaching and learning science from this epistemic perspective is established. Future studies should continue to explore the concepts and categories that this work leaves open.
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