Epididymal Adipose Tissue Weight Research Articles

Fatty acid and cholesterol synthesis in mice infected with the tapeworm Hymenolepis microstoma.

Infection with Hymenolepis microstoma significantly affected the lipid metabolism of young male Balb/C mice. Infection increased the rates of hepatic fatty acid and cholesterol synthesis and cholesterol synthesis by the gut. Decreases were recorded in testicular fatty acid synthesis and in the weights of testes and white epididymal adipose tissue. Plasma glucose decreased rapidly during infection. The observed changes in lipogenesis could not be attributed to changes in food intake or body temperature. The changes are discussed in relation to nutritional interactions between host and parasite and the possible effects on host hormone levels. The presence of newly synthesized fatty acid in H. microstoma is also reported.

Walker carcinoma 256: a model for studies on tumor-induced anorexia and cachexia.

Data on anorexia and cachexia induced by Walker carcinoma 256 in Sprague-Dawley rats were analyzed in order to standardize an experimental model using a statistical (nondeterministical) procedure for assessing the efficacy of potential orexigenic agents. This model was characterized by a mean survival time of 14 +/- 1 days and by food intake and body weight loss starting from day 6 after tumor implantation. The complex course of cachexia was characterized by reduction in the weight of gastrocnemius muscle and epididymal adipose tissue, taken as representative sites of loss of proteins and lipids.

Physiologic and genetic influences on regulation of glucose metabolism in adipose tissue of mice.

The influence of various agouti locus genotypes and phenotypes, castration, fat content of the diet and their interactions on the rates of glucose oxidation and conversion to lipid, blood glucose level, epididymal adipose tissue weight and body weight has been studied in male mice of the inbred YS/ChWf, VY/Wf, C3H/DiHeWf-Avy and NZO/BlWf strains. Although the lethal yellow (Ay) and viable yellow (Avy) genes, castration and a high fat content diet, all increased epididymal adipose tissue weight, the inducing mechanisms are probably different for each of these factors.

In vitro metabolism of epididymal adipose tissue from New Zealand obese hyperglycemic mice: Utilization of C 141-acetate and release of free fatty acids

The effect of different nutritional conditions on the in vitro utilization of C 14 1-acetate was studied in epididymal adipose tissue from New Zealand obese mice. Starvation resulted in a lower incorporation in tissue lipids per unit tissue nitrogen content, while no effect was found after starvation and refeeding. A significant release of free fatty acids (FFA) without a corresponding increase in tissue content of FFA was found in tissues from starved animals. There was an uptake of FFA from the medium into the epididymal adipose tissue of the mice which had been starved and subsequently refed. There total weight of epididymal adipose tissue was greater at 9 months than at 6 months of age. The results are discussed against the background of previous findings in mice with the American variety of the obese hyperglycemic syndrome.

INSULIN EFFECT ON ADIPOSE TISSUE SODIUM AND POTASSIUM.

SummaryIn rats weighing 97-171 g, there is a significant negative correlation between the [Na] and [K] per g of water in freshly dissected epididymal adipose tissue and total body weight. During in...

Extractable lipid, water and residue of rat epididymal fat bodies.

SummaryA high positive correlation (r= 0.9943) was observed between fresh weight and lipid content of epididymal adipose tissue weighing more than about 0.5-1.0 g. Above this value lipid concentration in the tissue was 80-85% and was relatively constant over a wide range of weights. These relations suggest that for tissues weighing more than 0.5-1.0 g the weight or lipid content of the tissue is the most sensitive measure of treatment effects; lipid concentration is more sensitive below these values.