Epidemiologic Studies Depression Scale Research Articles

Longitudinal association between ADL disability and depression in middle-aged and elderly: national cohort study.

The decline in daily living abilities (ADL) among older adults is a notable predictor of depressive symptoms and the occurrence of disease. However, the effects of changes in ADL disability on the progression of depression have not been extensively studied. This research aims to examine the relationship between current ADL disability and depression in individuals aged 45 and older, as well as to explore how ADL disability influences the progression of depression in later life within China. This study analyzed 7-year data from the China Health and Retirement Longitudinal Study (CHARLS), involving 2,205 middle-aged and older adults. The ADL disability (BADL: such as eating, dressing; IADL: such as shopping, cooking) were obtained using ADL scale (scores 0-12, lower is better), and depression was measured by the Center for Epidemiologic Studies Depression Scale (scores 0-30, lower is better). The latent growth curve and cross-lagged models were analyzed after adjusting relevant control variables to study the effect of ADL disability on the progression of depression. The mean values for depression, basic activities of daily living (BADL), and instrumental activities of daily living (IADL) varied from 9.44 to 11.08, 6.45 to 6.81, and 6.86 to 7.29, respectively. The analysis indicated a potential association between depression and ADL. Specifically, the trajectory of BADL was a significant predictor of both initial depression (β = 0.138, 95%CI = 0.039-0.237) and its trajectory (β = 0.579, 95%CI = 0.403-0.754). Although IADL did not significantly predict the trajectory of depression, it was a significant predictor of initial depression (β = 0.471, 95%CI = 0.404-0.538). Additionally, cross-lag regression analysis provided further support for the relationship between depression and BADL disability. This research highlights how ADL disability can forecast future depression in Chinese middle-aged and older adults. The findings indicate a significant connection between ADL disability and both changes in and future instances of depression in this group. Therefore, it is crucial for the Chinese government to prioritize interventions that enhance physical functioning in the elderly, as such measures can effectively mitigate the worsening of depression and promote positive aging.

Validating the questionnaire of achievement of developmental task (QADT) to measure achieving mental wellness in school-aged children.

This article presents a verification of the factor structure and validation of the Questionnaire of Achievement of Developmental Task (QADT), designed to measure children's social expectations in early childhood. Three tasks, important from the point of view of both children's functioning at a given life stage and preparation for the next developmental phase, were selected. These are school skills, cooperation with others and a sense of competence. The research aimed to verify the tool's psychometric validity and establish relationships between developmental tasks and indicators of children's mental health. The study was conducted in primary school's 4th, 5th and 6th grades (N = 453). The QADT, Brief Multidimensional Students' Life Satisfaction Scale and Center for Epidemiological Studies Depression Scale for Children were used. The tool shows sufficient validity and reliability. The hypothesis regarding associations between the level of developmental task completion and life satisfaction and depressive symptoms was also confirmed. The QADT tool can be used in scientific research. This work contributes to the growing body of literature on factors influencing children's mental health and underscores the importance of measuring social expectations of children in early childhood. It also highlights the need to consider developmental tasks in clinical practice and interventions to improve children's mental health. Ultimately, the findings of this study can inform the development of effective preventive and intervention strategies to promote children's mental health and well-being.

Anxiety and Depression Affect Sleep Quality: A Preliminary Investigation in Crowdsourced Samples of Autistic and Non-Autistic Adults.

We aimed to compare sleep problems in autistic and non-autistic adults with co-occurring depression and anxiety. The primary research question was whether autism status influences sleep quality, after accounting for the effects of depression and anxiety. We hypothesized that autistic adults would report higher levels of depression, anxiety, and sleep problems compared to non-autistic adults, after controlling for these covariates. We recruited 208 adults (109 non-autistic, 99 autistic) through a crowdsourcing platform, Prolific. Participants completed the Pittsburgh Sleep Quality Index, the Center for Epidemiologic Studies Depression Scale, and the Generalized Anxiety Disorder 7-item scale. Statistical analyses included Mann-Whitney U tests to compare group scores and a generalized linear model to assess the effect of autism status on sleep problems while controlling for depressive and anxiety symptoms. Autistic adults reported significantly higher levels of depressive and anxiety symptoms compared to non-autistic adults. However, after controlling for depression and anxiety, autism status alone did not have a statistically significant effect on overall sleep quality. The findings suggest that while autistic adults experience more severe sleep problems, these issues are closely related to higher levels of depression and anxiety rather than autism status itself. This study contributes to the understanding of sleep difficulties in autistic individuals, highlighting the importance of addressing co-occurring mental health conditions. Further research should explore the specific factors that exacerbate sleep problems in this population.

Persistent depressive symptom trajectory is associated with cognitive impairment: a population-based longitudinal study of aging in Taiwan

BackgroundTo investigate the associations between five depressive symptom trajectories and cognitive impairment in Taiwan’s older population. In addition, we investigated the moderating factors influencing these associations.MethodsThis population-based, longitudinal, cohort study was conducted on the basis of the Taiwan Longitudinal Study on Aging. Data corresponding to the fifth (2003), sixth (2007), and seventh (2011) survey waves were analyzed, focusing on individuals aged ≥ 65 years. Depressive symptom trajectories were analyzed using the 10-item Centre for Epidemiological Studies Depression scale, and cognitive function was assessed using the Short Portable Mental State Questionnaire. Logistic regression models were adjusted for various covariates such as sociodemographic, lifestyle, and health-related variables. We also investigated moderating effects of sex, age, type 2 diabetes mellitus, hypertension, and coronary heart disease.ResultsFive trajectories of depressive symptoms included 1,549 older individuals were identified. Approximately 36.09%, 47.13%, 5.68%, 6.20%, and 4.91% exhibited no, mild, decreasing, increasing, and persistent depressive symptom trajectories, respectively. The odds ratios for cognitive impairment were 3.17 (95% confidence interval [CI]: 1.41–7.15) in Model 1; 3.24 (95% CI: 1.42–7.41) in Model 2; and 2.95 (95% CI: 1.24–7.00) in Model 3 in individuals with persistent depressive symptom trajectory. Only persistent depressive symptom trajectory reached statistical significance in all three models. Cognitive decline was evident across all trajectories. The rate of cognitive decline was more rapidly in the persistent depressive symptom trajectory, nearly twofold to no depressive symptom trajectory, which the corresponding β values (score/year) were − 0.0862, − 0.1020, − 0.1192, − 0.1206, and − 0.1683 for the no, mild, decreasing, increasing, and persistent depressive symptom trajectories, respectively. Female sex, older age, type 2 diabetes mellitus, and coronary heart disease were significant moderators on the risk of cognitive impairment.DiscussionPersistent depressive symptoms is associated with cognitive impairment in older adults. Identifying high-risk subgroups is crucial for targeted assistance. Policymakers and health-care professionals should be informed accordingly.

Quality of life among Indonesian family caregivers caring for dependent older persons with type 2 diabetes mellitus in the community: A cross-sectional, correlational study.

The global prevalence of older adults with diabetes has increased, and family caregivers in Indonesia play a critical role in managing diabetes and providing personal care. However, caregiving can be complex and challenging, often negatively affecting caregivers' quality of life (QoL). This study aimed to develop and test a hypothesized causal model of QoL among Indonesian family caregivers who care for dependent older persons with type 2 diabetes mellitus (T2DM) in 2024. A cross-sectional, correlational study was conducted with 270 family caregivers recruited from five Community Health Centers. Data were collected using various scales: the Center for Epidemiologic Studies Depression Scale, the Zarit Burden Interview, the Duke University Religion Index, the Perceived Knowledge on T2DM Care Scale, the Family-Carer Diabetes Management Self-Efficacy Scale, the Multidimensional Scale of Perceived Social Support, and the Quality-of-Life Index. Descriptive statistics and Partial Least Squares Structural Equation Modeling (PLS-SEM) were used for analysis. The final model explained 89.1% of the variance in the quality of life (QoL) of family caregivers (R2 = 0.893, Adjusted R2 = 0.891), with 66% predictive relevance. Depression symptoms had the strongest negative direct effect on QoL, followed by caregiver burden. Self-efficacy and perceived knowledge had positive direct effects, while social support showed no significant direct effect. Indirect effects revealed that social support and self-efficacy positively influenced QoL through depression symptoms. The total effect (TE) analysis confirmed that depression symptoms had the strongest negative effect on QoL (TE = -0.744, p <0.001), while social support (TE = 0.443, p <0.001) and self-efficacy (TE = 0.413, p <0.001) had positive effects. Reducing depression symptoms and caregiver burden, strengthening social support, and promoting self-efficacy could significantly improve the QoL of family caregivers who care for older persons with T2DM. Nursing practice should address caregivers' physical and emotional needs, provide education, foster social support, and support caregiver mental health.

The longitudinal association between multiple cardiometabolic diseases, socioeconomic status, and depressive symptoms in China

The aim of this study is to investigate the effect of cardiometabolic diseases (CMDs) on the development of depressive symptoms and to determine whether socioeconomic status (SES) moderates this effect. A total of 6,455 individual free from depressive symptoms were selected from the China Health and Retirement Longitudinal Study (CHARLS). CMDs and SES were self-reported. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CESD-10). Cox proportional hazards regression models were employed to examine the association between baseline CMDs and subsequent depressive symptoms. Stratified analysis were conducted to explore the moderating effect of SES on this association.Participants with any CMDs exhibited a higher risk of developing depressive symptoms compared to those without CMDs, with a hazard ratio (HR) of 1.10 (95% CI: 1.01, 1.20). Individuals with one CMD (HR = 1.08, 95% CI: 1.00, 1.20) or cardiometabolic multimorbidity (HR = 1.13, 95% CI: 1.02, 1.26) also demonstrated an increased risk. The effect of CMDs on depressive symptoms was observed primarily in adults aged 60 years and older with lower education attainment (HR = 1.28, 95%CI: 1.12, 1.46), lower income (HR = 1.29, 95%CI: 1.11, 1.50) and rural residency (HR = 1.29, 95%CI: 1.12,1.51). These findings emphasize the importance of closely monitoring the mental status of patients with CMDs and considering routine screening and evaluation for depressive symptoms, especially in individuals with low SES.

Depressive intensity, duration, and their associations with cognitive decline: a population-based study in Korea.

Existing epidemiological studies have ignored the effect of depressive duration on cognitive decline despite the presence of biological cues and understudied the depression-cognition association in Asian countries in the context of increasing cognitive burden worldwide. We aimed to comprehensively characterize the effects of depressive duration and intensity on cognitive decline at the population level. A total of 6406 individuals from the Korean Longitudinal Study of Aging (KLoSA) from 2010 to 2018 were included to generate four datasets with durations of 2, 4, 6, and 8years. Depressive intensity was categorized as no, mild, and major depression according to the Center for Epidemiological Studies Depression scale (CES-D10), and duration was measured by the span of consecutive interviews. Cognitive function was assessed using the Korean Mini-Mental Status Examination (K-MMSE). Multiple linear regressions and meta-regressions were used to estimate the effects of depressive intensity and duration on global cognition and seven cognitive subdomains. Stratified analyses were performed to explore effect differences between subpopulations of different sexes and ages. The potential bias in the effect of depressive intensity on cognitive decline when ignoring duration was also explored. On average, a 1-year longer duration decreased the global cognitive scores by 0.44 (95% CI 0.36, 0.51) across intensities and major depression decreased the scores by an additional 0.82 (95% CI 0.59, 1.04) points than mild depression across durations. Similar trends held for seven cognitive subdomains except for visual construction. Older adults suffered more cognitive decline from major depression than middle-aged adults did. More severe and longer-duration depression lead to greater cognitive decline. Ignoring depressive duration can lead to an overestimated effect of depressive intensity on cognitive decline. The depressive effects and susceptible populations clarified in our study have important implications for the preservation of cognitive health in Asian region.

Multimorbidity and Depressive Symptoms and their Association with Self-Reported Health and Life Satisfaction Among Adults Aged ≥ 50 Years in Mexico.

Identify the association between multimorbidity and depressive symptoms (DS) with self-reported health (SRH) and life satisfaction in a national sample of Mexican ≥ 50 years older adults. Data are drawn from the Mexican Health and Aging Study (MHAS), a cross-sectional study conducted in 2018 involving 14,230 older adults aged 50 years and older living in urban and rural areas of Mexico. Depressive symptoms were measured using the Center for Epidemiological Studies depression scale (CES-D) and life satisfaction using the Life Satisfaction Scale (LSS), examined both as a categorical and continuous variable. Logistic and Poisson regression analyses were used to assess the association adjusting for confounders. The prevalence of multimorbidity was 25.8%. Age (≥ 65 years) was significantly associated with increased odds of fair/poor SRH [OR = 1.17 (95% CI 1.09-1.27)]. Older adults with multimorbidity and high DS were more likely to present fair/poor SRH [OR = 7.83 (95% CI 6.48-9.45)]. Older adults with multimorbidity and high DS were 37% [RR = 1.37 (95% CI 1.35-1.40)] more likely to present low life satisfaction than those that did not present multimorbidity. Multimorbidity and high DS were found to be associated with fair/poor SRH and low life satisfaction. The early identification of factors related to multimorbidity, DS, and low life satisfaction are important in order to reduce possible complications and improve quality of life.

P0467 Increased risk for depression and low quality of life in patients with active inflammatory bowel disease

Abstract Background Patients diagnosed with inflammatory bowel disease (IBD) are at increased risk of developing mental health issues, such as depression, especially when experiencing disability and poor quality of life (QoL). Recent studies showed that the relationship between depression and IBD appears to be bidirectional, through the brain-gut axis. Methods We aimed to evaluate the risk for depression and the QoL in patients with active IBD hospitalized between January 2021-April 2024 in our clinic, at the moment of biologic initiation and at 6 months follow-up, for those achieving clinical remission. We screened for symptoms of depression using the self-administered Center for Epidemiologic Studies Depression Scale (CES-D) – ranging score 0-60 (0-15 no to mild; 16-23 moderate; 24-60 severe symptomatology). The self-administered Short Inflammatory Bowel Disease Questionnaire (SIBDQ) was used to evaluate the health-related QoL through social, bowel, emotional and systemic dimension, with a score ranging from 10 (poor) to 70 (optimal). Results We included 47 patients (53.19% ulcerative colitis, 57.44% males, age 38.51±12.26 years old), with a disease duration of 6.43±6.28 years. 21 patients were reevaluated at 6 months. In patients with active IBD, the CES-D score was 14.15±13.04 and the SIBDQ score was 42.2±15.8 (42.6±19.2 social; 44.3±16 bowel; 43.6±16.9 emotional; 36.5±18 systemic). 18 patients (38.29%) were at risk for clinical depression, of whom 11 patients (23.40%) had severe depressive symptomatology. Patients being at risk for depression had lower SIBDQ scores (p&amp;lt;0.001), lower levels of serum albumin (p=0.007) and lower body mass index (p=0.004). In the subgroup analysis, both CES-D (17.23±15.63 vs. 8.09±7.19, p=0.005) and SIBDQ (40.81±16.45 vs. 56.09±10.68, p=0.002) were significantly improved after achieving clinical remission. Conclusion Considering the high rate of patients prone for depressive symptomatology, screening tools for depression and assessing QoL should be routinely used, and specialized psychiatric treatment should be integrated in the comprehensive care for IBD patients.

Traffic pollution, reproductive health, and depressive symptoms in a healthy multiethnic sample of reproductive age women in the Ovarian Aging Study.

This study aimed to determine whether exposure to traffic-related air pollution (TRAP) is associated with depressive symptoms while also characterizing the contribution of key explanatory factors related to sociodemographics and health. In addition, it aimed to also explore the role of reproductive health as a pathway through which exposure to TRAP may relate to depressive symptoms. Participants were 688 healthy reproductive-age women in the Ovarian Aging Study. TRAP was derived from distance-weighted traffic counts using residential addresses. Depressive symptoms were assessed by the Center for Epidemiological Studies Depression scale. Explanatory factors were assessed by interview and clinic measures, including demographics (age, race/ethnicity), socioeconomic status (SES) (individual SES, neighborhood SES), general health (smoking, body mass index), and reproductive health (menarcheal age, contraceptive use, parity, menstrual cycle characteristics). In cross-sectional, step-wise multivariate regression analyses, greater exposure to TRAP was related to more depressive symptoms (b = 0.779, P = 0.015). Lower individual SES, longer menstrual cycle length, and experiencing change (vs no change) in menstrual cycle length were also related to more depressive symptoms (P's < 0.05). Examination of each model step showed that variance in depressive symptoms was attributable to TRAP (1.2%, P = 0.004), demographics (1.0%, P = 0.217), SES (1.4%, P = 0.007), general health (0.3%, P = 0.356), and reproductive health (2.0%, P = 0.015). Finally, menstrual cycle length, a marker of reproductive health status, partially mediated effects of TRAP on depressive symptoms (indirect effect: b = 0.064, P = 0.020). Findings showed that exposure to TRAP is associated with depression, along with SES and reproductive health factors, and that reproductive health may be a pathway through which TRAP relates to depression.

Association of high complement and low immunoglobulins with the clinical symptoms of patients with fibromyalgia

BackgroundFibromyalgia (FM) is a disease characterized by chronic widespread pain concomitant with various symptoms such as fatigue and anxiety. Although chronic inflammation has been implicated in the immunological abnormalities of FM, there are few human studies on complement and immunoglobulins. In this study, we investigated the immunological characteristics of FM patients and the association between their clinical symptoms and immunological indices, including complement and immunoglobulins.Methods1) The serum 50% hemolytic complement activity (CH50), C3, C4, IgG, IgM, and hsCRP of 36 FM patients and 30 healthy sex- and age-matched controls (HC) were measured and compared. 2) Data from the Brief Pain Inventory (pain intention and pain interference subscales), the visual analog scale (VAS) (low back pain, knee pain, and fatigue), the State-Trait Anxiety Inventory and the Center for Epidemiologic Studies Depression Scale (anxiety and depression), and CH50, IgG, and hsCRP as immunological indices were acquired for 41 FM patients. Correlation analysis was done of the clinical symptom and immunological indices.Results1) The FM group had significantly higher CH50 and lower IgG and IgM than the HC group after adjusting for body mass index (BMI). 2) Correlation analysis of immunological indices and clinical symptoms showed a positive, partial correlation between CH50 and fatigue and trait anxiety after adjusting for sex, age, and BMI.ConclusionsFM patients had higher CH50 and lower immunoglobulin levels than HCs. CH50 was also associated with the fatigue and trait anxiety of FM patients. Further studies are needed to determine whether changes in these immunological indices can be used as biomarkers and/or therapeutic targets for FM.

Depressive symptoms among middle-aged and older adults in China: The interaction of physical activity and sleep duration.

Previous research on the interaction of physical activity and sleep on depressive symptoms was mostly cross-sectional or conducted with children or young adults. This study examines the main and interactive associations of physical activity and sleep duration with depressive symptoms over a 3-year period among middle-aged and older Chinese adults. Data from 4269 Chinese adults aged 45 or older from the China Health and Retirement Longitudinal Study (CHARLS) were used. Physical activity was categorized as inadequate (<600 MET), adequate (600-8000 MET), and extremely high (>8000 MET). Sleep was classified as inadequate (<6hours), adequate (6-9hours), and excessive (>9hours). The Center for Epidemiologic Studies Depression Scale (CES-D) was used to measure depressive symptoms. Inadequate sleep was linked to greater increases in depressive symptoms over 3years. A significant interaction between baseline physical activity and sleep duration in predicting depressive symptoms at the 3-year follow-up showed that inadequate sleep, when combined with either inadequate or extremely high physical activity, was associated with higher depressive symptoms at the 3-year follow-up. In middle-aged subgroups, for people with either inadequate physical activity or an extremely high level of physical activity, inadequate sleep was associated with higher CES-D score compared to adequate sleep; for older adults, only inadequate sleep was associated with a higher follow-up CES-Dscore. Physical activity and sleep interactively impacted depressive symptoms, suggesting future personalized interventions that simultaneously target physical activity and sleep. Adequate sleep was associated with lower levels of future depressive symptoms in people with inadequate or extremely high physical activity.

Depression and Incident Hypertension: The Strong Heart Family Study.

Compared with White Americans, American Indian adults have disproportionately high depression rates. Previous studies in non-American Indian populations report depression as common among people with uncontrolled hypertension, potentially interfering with blood pressure control. Few studies have examined the association of depressive symptoms with hypertension development among American Indians despite that population's high burden of depression and hypertension. We examined the association of depressive symptoms with incident hypertension in a large cohort of American Indians. We studied 1,408 American Indian participants in the Strong Heart Family Study, a longitudinal, ongoing, epidemiologic study assessing cardiovascular disease and its risk factors among American Indian populations. Depressive symptoms were assessed by using the Center for Epidemiological Studies-Depression (CES-D) scale, 2001-2003. At each study examination in 2001-2003 and 2007-2009, blood pressure was measured 3 times. The average of the last 2 measurements taken at baseline and follow-up examinations was used for analyses. Incident hypertension was defined as systolic blood pressure ≥140 mm Hg, diastolic blood pressure of ≥90 mm Hg, or use of hypertension medications at follow-up. To account for within-family correlation, we used generalized estimating equations to examine the association of depressive symptoms with incident hypertension. During follow-up, 257 participants developed hypertension. Participants with symptoms consistent with depression (CES-D ≥16) at baseline had 54% higher odds of developing hypertension during follow-up (OR = 1.54; 95% CI, 1.06-2.23) compared with those without depression (CES-D <16) at baseline after adjustment for other risk factors. These data suggest that participants who experienced symptoms consistent with depression were at increased odds of incident hypertension.

Food Allergy and Mental Health in Children and Adolescents-The Role of Shared Familial Environment.

Evidence suggests a link between food allergy and poor mental health, however, this may be explained by shared genetic and environmental factors. We aimed to investigate the association between food allergy of different severity and mental health in children, and the role of familial factors. This population-based, longitudinal cohort study is based on the Child and Adolescent Twin Study in Sweden with questionnaire data reported by parents and/or children. Food allergy 'ever' and doctor's diagnosis were reported at age 9-12 years, and ≥ 1 recent dispensation of adrenaline was used as a marker for current severe food allergy. Outcomes were identified using validated questionnaires for anxiety; Screen for Child Anxiety Related Disorders (SCARED); Strength and Difficulties Questionnaire (SDQ) and depression; Short Mood and Feelings Questionnaire (SMFQ), Center for Epidemiological Studies Depression Scale (CES-D) and Diagnostic and Statistical manual of Mental Disorders (DSM-IV-MDE) and reported at 9-12, 15 and 18 years of age. Multivariate linear and logistic modelling was applied to the whole cohort and a co-twin control approach to remove confounding by familial factors. In total, 3039 (8.9%) children had a parent-reported food allergy. Among these, 1292 (43.5%) had non-severe food allergy without diagnosis, 1490 (49%) had non-severe food allergy with diagnosis and 257 (8.5%) had severe food allergy. Compared to children with no food allergy, non-severe food allergy with diagnosis by 9-12 years was associated with parent-reported anxiety/depression; SCARED (adjOR 2.10, 95% CI 1.48-2.98), SMFQ (adjOR 1.92, 95% CI 1.19-3.10) at 9-12 years and SDQ (adjβ 0.2, 95% CI 0.0-0.4) at 15 years. All other associations were null including for those with severe food allergy. All positive estimates in the full cohort were attenuated using co-twin controls. Evidence associating paediatric food allergy severity and poor mental health was weak, and positive associations observed were likely due to familial confounding.

Relationship Between Poor Sleep and Depressive Symptoms in Korean Elite Youth Athletes.

Background: Sleep and mental health are crucial to elite youth athletes, who face combined pressures of training, competition, school, and social commitments. We examined the association between sleep and depression in elite youth athletes. Methods: We analyzed data of 248 Korean world-class youth athletes (aged 13-19 years). The athletes completed the Pittsburgh Sleep Quality Index (PSQI), the Morningness-Eveningness Questionnaire (MEQ), and the Center for Epidemiologic Studies Depression Scale (CES-D). Results: Overall, 50.4% of the athletes were considered poor sleepers (global PSQI score ≥ 5.5); 23.8% reported depressive symptoms (CES-D score ≥ 16). Depression was 4.26 times (95% confidence interval [CI], 2.00-9.09, p < 0.001) more likely in poor than in good sleepers. Odds of depression were increased with poor subjective sleep quality (odds ratio [OR]: 4.62; 95%CI, 2.10-10.18, p < 0.001), prolonged sleep latency (OR: 2.45: 95% CI, 1.28-4.69, p < 0.01), increased sleep disturbances (OR: 3.98: 95% CI, 1.83-8.63, p < 0.001), and daytime dysfunction (OR: 3.28; 95% CI, 1.67-6.44, p < 0.001). Depressive symptoms were associated with worse sleep, particularly poor subjective sleep quality, prolonged sleep latency, increased sleep disturbances, and increased daytime dysfunction. Conclusions: These results suggest that depressive symptoms are associated with poor sleep in the elite youth athlete population.

The Association Between Posting WeChat Moments and the Risk of Depressive Symptoms Among Middle-Aged and Older Chinese Adults: Prospective National Cohort Study.

The association between social media usage and the risk of depressive symptoms has attracted increasing attention. WeChat is a popular social media software in China. The impact of using WeChat and posting WeChat moments on the risk of developing depressive symptoms among community-based middle-aged and older adults in China is unknown. The objective was to assess the association between using WeChat and posting WeChat moments and the risk of depressive symptoms among middle-aged and older adults in China. A prospective national cohort study was designed based on the data obtained from the fourth and fifth waves of the China Health and Retirement Longitudinal Study (CHARLS). The strength of association between using WeChat and posting WeChat moments and the risk of depressive symptoms was estimated by modified Poisson regressions. Depressive symptoms were determined using the 10-item Center for Epidemiologic Studies Depression Scale. Meanwhile, the heterogeneity of the associations was explored through multiple subgroup analyses. Moreover, multiple sensitivity analyses were performed to verify the robustness of the associations between the exposures and depressive symptoms. A total of 9670 eligible participants were included in the cohort study, and the incidence rate of depressive symptoms was 19.08% (1845/9670, 95% CI 19.07%-19.09%) from the fourth to fifth waves of the CHARLS. Using WeChat (adjusted relative risk [aRR] 0.691, 95% CI 0.582-0.520) and posting WeChat moments (aRR 0.673, 95% CI 0.552-0.821) reduced the risk of depressive symptoms among middle-aged and older Chinese adults. The association between the exposures and depressive symptoms was robust, proved through multiple sensitivity analyses (all P<.05). However, the associations were heterogeneous in certain subgroup catagories, such as solitude, duration of sleep at night, nap after lunch, physical activity, and having multiple chronic conditions. Using WeChat and especially posting WeChat moments can mitigate the risk of depressive symptoms among community-based middle-aged and older Chinese adults. However, there is likely a need for a longer follow-up period to explore the impact of the exposures on the risk of long-term depressive outcomes.

Emotional well-being in transition-age adults with pediatric-onset disabilities: A cross-sectional study.

The transition from childhood to adulthood often involves emotional challenges. These problems may be especially prominent for transition-age adults (TAA) with pediatric-onset disabilities, although there are currently few studies that speak to this. The aim of this study is to characterize depressive symptoms and the association with family functioning in a sample of TAA with pediatric-onset disabilities. This sample is comprised of 55 TAA (18-28 years of age, M = 20.88, SD = 2.49) who were followed by pediatric rehabilitation medicine clinics. Participants have childhood acquired brain injury (n = 17), spina bifida (n = 10), or neuromuscular disorders (n = 28). Participants completed the Center for Epidemiological Studies-Depression scale and the Family Assessment Device Short Form. Clinically elevated depressive symptoms were endorsed by 65.4% of the sample. Forty-five percent of those with elevated depressive symptoms were not currently receiving psychotherapy services. Poorer family functioning on the Family Assessment Device Short Form and older age were independently associated with more depressive symptoms, controlling for medical condition, mobility status, and other relevant sociodemographic factors. Emotional problems are quite common in TAA with a history of acquired brain injury, spina bifida, and neuromuscular disorders, yet are seemingly inadequately managed. In view of the results of this study, TAA with pediatric-onset disabilities are likely to benefit from interventions that bolster emotional well-being and target risk factors related to their family system. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

What Is in a Name? Depression and Anxiety Symptoms in Collegiate Athletes With and Without a History of Concussion.

Athletes with a history of concussion (CON) have been demonstrated to have heightened levels of anxiety and depression that may continue well beyond the resolution of concussion symptoms. The global events of 2020 resulted in elevated levels of anxiety and depression in the general population, which may have unequally presented in collegiate athletes with (CON) than those without a history of concussion (NoCON). Using a deception design, our survey-based study compared levels of anxiety and depression in CON and NoCON collegiate athletes in response to the pandemic and social injustices. We hypothesized that the CON group would have significantly elevated anxiety and depression as compared to the NoCON group in response to events of 2020. Collegiate athletes (N = 106) during the academic 2020-2021 academic year were divided into CON and NoCON groups based on their preinjury (baseline) concussion assessment. Participants completed the Social Readjustment Rating Scale(SSRS), Center for Epidemiologic Studies Depression Scale(CES-D), and Generalized Anxiety Disorder Scale-7(GAD-7) via an electronic survey pertaining to the events of 2020. The term "concussion" was not used in any study materials which was the basis for our deception-based design. An analysis of covariance was used to compare group CES-D and GAD-7 outcome scores while controlling for the SSRS outcome score. Our survey response rate was 14.2% (48/337 [77.1% female]) and 10.1% (58/580 [67.2% female]), for the NoCON and CON groups, respectively. The NoCON group had significantly (F1 = 5.82, P = .018, ηp2=.06) higher anxiety (8.3 [5.89]) as compared to the CON group (5.5 [2.85]). The NoCON group also had significantly (F1 = 13.7, P < .001, ηp2=.12) higher levels of depression (21.0 [12.52]) as compared to the CON group (16.07 [9.10]). Our deception-based study revealed NoCON participants had elevated and clinically relevant mood states as compared to CON participants in response to the events of 2020.

Associations between biomarkers of inflammation and depressive symptoms—potential differences between diabetes types and symptom clusters of depression

Inflammation is a probable biological pathway underlying the relationship between diabetes and depression, but data on differences between diabetes types and symptom clusters of depression are scarce. Therefore, this cross-sectional study aimed to compare associations of a multimarker panel of biomarkers of inflammation with depressive symptoms and its symptom clusters between people with type 1 diabetes (T1D) and type 2 diabetes (T2D). This cross-sectional study combined data from five studies including 1260 participants (n = 706 T1D, n = 454 T2D). Depressive symptoms were assessed using the Center for Epidemiological Studies-Depression Scale (CES-D). Serum levels of 92 biomarkers of inflammation were quantified with proximity extension assay technology. After quality control, 76 biomarkers of inflammation remained for statistical analysis. Associations between biomarkers and depressive symptom scores and clusters (cognitive-affective, somatic, anhedonia) were estimated with multivariable linear regression models. Nine biomarkers were positively associated with depressive symptoms in the total sample (CCL11/eotaxin, CCL25, CDCP1, FGF-21, IL-8, IL-10RB, IL-18, MMP-10, TNFRSF9; all p < 0.05) without interaction by diabetes type. Associations differed for eight biomarkers (pinteraction < 0.05). TNFβ was inversely associated with depressive symptoms in T1D, whereas three biomarkers (GDNF, IL-18R1, LIF-R) were positively associated with depressive symptoms in T2D. For the remaining four biomarkers (CD6, CD244, FGF-5, IFNγ) associations were not significant in either subgroup. Biomarker associations were more pronounced with somatic and anhedonia than with cognitive-affective symptoms. These results indicate that different proinflammatory pathways may contribute to depression in T1D and T2D and that there may be a symptom specificity in the link between subclinical inflammation and depression.

Predicting depressive symptoms and psychological distress by circulating inflammatory mediators: A 16-month prospective study in Japanese white-collar employees.

Although increasing evidence suggests that depression/distress involves inflammatory processes, its potential sex differences and the temporal directions for this association remain elusive. We examined the temporal association between serum inflammatory mediators and depression/distress as measured by the Center for Epidemiologic Studies Depression Scale (CES-D) and the Kessler Psychological Distress Scale (K6), in non-depressed working men and women (n = 61 and 43, respectively) by a 16-month prospective design. Fully-adjusted partial correlation analyses revealed that in men, a lower IFN-γ predicted subsequent increases in CES-D and K6 scores, while a higher TNF-α predicted increased K6 scores. In women, a higher IFN-γ predicted a subsequent increase in the CES-D score. CES-D and K6 scores did not predict inflammatory mediators at follow-up. The finding suggests that inflammatory activation precedes depression/distress with distinct sex differences.