Groundwater is essential for a sustainable future, yet identifying potential groundwater zones remains challenging in regions with varied hydro-geological conditions. Nagaland is a state in north-eastern India characterized by diverse terrain, complex geological formations, and seasonal variations in rainfall. The objective of the present study is to evaluate groundwater potential zones in Nagaland using an integrated Geographic Information System (GIS) and Analytical Hierarchy Process (AHP) methodology, resulting in the first comprehensive map addressing the region's diverse hydro-geological conditions. Several attributes like geomorphology, geology, slope, soil, rainfall, drainage density, and Land use/Land cover (LU/LC) were generated from available data resources like Landsat 8 and Sentinel-2 satellite imageries, the Geological Survey of India (GSI), Environmental Systems Research Institute (ESRI), the Food and Agriculture Organization (FAO), and the Climatic Research Unit (CRU). These datasets are extracted using the Arc-GIS (Arc-GIS Desktop 10.8.1), with weights assigned according to Saaty's scale, and subsequently normalized through the AHP. The findings reveal that 14% (2240km2) of the state has very good groundwater potential, 42% (6720 km2) is classified as good, 9% (1440 km2) as moderate, 27% (4320 km2) as poor, and 8% (1280 km2) as very poor. These insights are significant for regions like Mokokchung, Longleng, and Wokha, which require urgent intervention. Conversely, the study identifies Dimapur and Chumoukedima as areas with significant groundwater potential, capable of meeting rising water demands. The validation of these results using well discharge data from 12 monitoring wells supports these findings.