Environmental Issues Research Articles

UNISON framework with fuzzy decision tree for water conservation in the dynamic scheduling of the textile dyeing process

PurposeThis study aimed to optimize the dyeing scheduling process with uncertain job completion time to reduce resource consumption and wastewater generation, and while reconciling the conflicting objectives of minimizing the makespan and the need to limit the production on specific machines to minimize rework.Design/methodology/approachWe employed a UNISON framework that integrates fuzzy decision tree (FDT) to optimize dyeing machine scheduling by minimizing the makespan and water consumption, in which the critical attributes such as machine capacity and processing time can be incorporated into the scheduling model for smart production.FindingsAn empirical study of a high-tech textile company has shown the validity and effectiveness of the proposed approach in reducing the makespan and water consumption by over 8% while high product quality and efficiency being maintained.Originality/valueHigh-tech textile industry is facing the challenges in reducing the environmental impact of the dyeing process while maintaining product quality and efficiency for smart production. Conventional scheduling approaches have not addressed the relationship between machine groups and reworking, resulting in difficulty in controlling the makespan and water consumption and increasing costs and environmental issues. The proposed approach has addressed uncertain job completion via integrating FDT into the scheduling process to effectively reduce makespan and wastewater. The results have shown practical viability of the developed solution in real settings.

Design and Testing of a Small-Scale Composting Facility for Sheep Manure Utilizing Aeration and Thermal Treatment

Inner Mongolia has the largest sheep population among China’s provinces, resulting in the production of a substantial amount of sheep manure. If left untreated, this manure can contribute to environmental pollution. However, sheep manure serves a dual purpose: it can be both a pollutant and a valuable source of organic fertilizer. Consequently, there is an urgent need to address the environmental issues arising from manure accumulation and its unused status. In this paper, a viable solution is proposed: the conversion of manure into fertilizer through a composting unit incorporating high-temperature aerobic fermentation technology. This unit, tailored for small farms and individual farmers, integrates critical functions such as ventilation, heating, and turning. Additionally, it boasts excellent thermal insulation, enhancing composting efficiency and enabling precise control over fermentation conditions. This design mitigates heat loss and accelerates maturation, addressing common challenges in traditional composting. The design process encompassed both equipment construction and control systems, with a primary focus on compost fermentation and aeration heating. The components were carefully designed or selected based on theoretical analysis and subsequently validated using simulation software, including EDEM and Fluent. The control system seamlessly integrates a touch screen interface, PLC programming, and control circuits to manage air pumps and electric heaters in response to changes in temperature and oxygen concentration. Furthermore, it controls the motors during the recovery phase. A comprehensive performance evaluation was conducted, revealing notable improvements. Under artificially heated conditions, the maximum temperature of the compost increased by approximately 20 °C, the composting cycle was reduced by roughly 4 days, and the seed germination index (GI) rose by about 9% when compared to natural fermentation. Thus, this device significantly accelerates composting and improves fertilizer quality by increasing the decomposition rate.

The Mediating Impact of Organizational Innovation on the Relationship Between Fintech Innovations and Sustainability Performance

The paper explores the impact of digital payment systems, blockchain technology, and AI/machine learning on innovation and sustainability in financial organizations. As part of the analysis, the study has adopted an explanatory research design and has used SmartPLS in order to analyze the data collected from 230 professionals of different fields through a structured questionnaire. The results show positive effects of digital payment systems and blockchain technology on organizations’ innovations with the impact of digital payments being the most pronounced. Empirical results suggest that these technologies are important to improve sustainability performance, depending on measures of internal consistency and discriminant validity among the proposed constructs. Al, also machine learning, has the highest relevance with environmental sustainability, thereby underlining the importance and work of such measures. Based on the Resource-Based View (RBV) theory, the study also explains the need for the organization to assimilate these innovations to enhance the organizational operations, customer satisfaction, and compliance with the laws. The study highlights fintech’s potential to address environmental issues and enhance societal goals, but geographical limitations may obstruct its transportability.

Adsorption Properties of Fishbone and Fishbone-Derived Biochar for Cadmium in Aqueous Solution

Cadmium (Cd) contamination in aquatic ecosystems is a serious global environmental issue. Biochar derived from agricultural wastes has recently attracted remarkable attention as it is used as an absorbent in combating heavy metal contamination of water bodies. In the present study, the absorption efficacy of fish bone (FBM) and fishbone-derived biochar prepared at 200 °C, 400 °C, 600 °C, and 800 °C (referred to as B200, B400, B600, and B800, respectively) for the Cd ion (Cd2+) in aqueous solution was investigated. The results showed that high-temperature pyrolysis could optimize the pore structure and specific surface area of FBM, and Cd2+ successfully adsorbed onto FBM and fishbone-derived biochar. High-temperature pyrolysis significantly increased the FBM adsorption capacity for Cd2+ by 49.5–135.1%, with the optimal pyrolysis temperature being 600 °C. Furthermore, the kinetic data of FBM and fishbone-derived biochar for Cd2+ were in better alignment with the pseudo-second-order model, their adsorption isotherms were better in accordance with the Langmuir models, and the thermodynamic analysis showed that the adsorption process was monolayer and favorable adsorption. Moreover, the potential adsorption mechanisms of Cd2+ on FBM and fishbone-derived biochar might be related to pore filling, ion exchange, complexation with oxygen functional groups, and precipitation with the minerals on the biochar surface. Fishbone-derived biochar has significant potential for wastewater treatment and agricultural waste applications.

HIGH-ADDED VALUE PRODUCTS FROM DISCARDED COOKING OIL

Vegetable oils are widely used in human consumption as food, with increasing productivity. As they are sustainable raw materials, they are suitable substitutes for fossil-derived raw materials and have great potential for producing high-value bioproducts, contributing to sustainability, the economy, and environmental issues. This article explores multiple applications of vegetable oils, highlighting residual oil included in making soaps, biofuels, animal feed, green solvents, bioasphalt, and asphalt binders. It also addresses the treatment of these vegetable oils with enzymes and the methods for converting soybean oil into biofuels, highlighting their properties that favor efficiency and the reduction of pollutant gas emissions. In addition, the extraction and purification processes that make obtaining ingredients with more excellent market value possible are discussed.

An Experimental Study on Concrete Strength Optimization with Surkhi as

Concrete is a widely used construction material, with sand as key component. However, excessive extraction of sand has led to a significant environmental consequences, including erosion, ecological imbalance, habitat destruction, and water quality issues. This study aims to develop an economical and sustainable alternative to traditional sand-based concrete while maintaining its structural integrity. It explores the potential of using Surkhi (a waste product from burnt clay bricks) as a partial replacement of sand in concrete. For this study, 120 concrete cube samples were prepared in the laboratory.Concrete cubes of M20 and M25 grades were prepared using design and nominal mixes, with different proportions of Surkhi (0%, 10%, 20%, 30%, and 40%) and tested to evaluate the workability, cost-effectiveness, and compressive strength. Compressive strength tests were conducted on concrete cubes at 7 and 28 days to investigate their mechanical properties. The results shows that a 10% replacement of sand with Surkhi optimizes the strength and workability of concrete without compromising its performance, thus supporting sustainable construction practices. However, the negative impact in concrete strength due to addition of higher proportions of Surkhi should be carefully considered. Furthermore, a cost analysis indicates that replacing sand with Surkhi can help to reduce the production costs, while promoting its use as an eco-friendly alternative. The findings provides valuable insights into the potential of Surkhi to reduce environmental damage and costs without compromising performance at moderate replacement levels. However, further research is recommended to assess the long-term durability and structural integrity of Surkhi-based concrete in various applications.

Engaged Amazigh Poetry in Meteor Airlines' "Agdal": Reviving Tradition while Addressing Global Environmental Issues

This paper analyzes Meteor Airlines' 2024 album Agdal, which revitalizes traditional Amazigh poetry through the emerging genre of Amazigh Rock. The study aims to explore how Agdal integrates the cultural heritage of pre-Saharan Amazigh oasis communities into global environmental discussions, with an emphasis on preserving nomadic and pastoral traditions. Using a qualitative analysis of the album’s lyrics, music style, and its reception, this research examines how the album marks a shift in Morocco's cultural industry from commercialized music production to efforts centered on cultural preservation and archiving. Findings suggest that Agdal, by merging traditional Amazigh poetry with contemporary rock elements, engages transnational audiences and contributes to an ongoing global dialogue on ecological and cultural sustainability. The study concludes that contemporary Amazigh music plays a crucial role in preserving historical memory, fostering cultural resilience, and raising environmental awareness, illustrating the impact of local cultural production on wider global issues

Environmental Impact of Wind Farms

The aim of this article is to analyse the global environmental impact of wind farms, i.e., the effects on human health and the local ecosystem. Compared to conventional energy sources, wind turbines emit significantly fewer greenhouse gases, which helps to mitigate global warming. During the life cycle of a wind farm, 86% of CO2 emissions are generated by the extraction of raw materials and the manufacture of wind turbine components. The water consumption of wind farms is extremely low. In the operational phase, it is 4 L/MWh, and in the life cycle, one water footprint is only 670 L/MWh. However, wind farms occupy a relatively large total area of 0.345 ± 0.224 km2/MW of installed capacity on average. For this reason, wind farms will occupy more than 10% of the land area in some EU countries by 2030. The impact of wind farms on human health is mainly reflected in noise and shadow flicker, which can cause insomnia, headaches and various other problems. Ice flying off the rotor blades is not mentioned as a problem. On a positive note, the use of wind turbines instead of conventionally operated power plants helps to reduce the emission of particulate matter 2.5 microns or less in diameter (PM 2.5), which are a major problem for human health. In addition, the non-carcinogenic toxicity potential of wind turbines for humans over the entire life cycle is one of the lowest for energy plants. Wind farms can have a relatively large impact on the ecological system and biodiversity. The destruction of animal migration routes and habitats, the death of birds and bats in collisions with wind farms and the negative effects of wind farm noise on wildlife are examples of these impacts. The installation of a wind turbine at sea generates a lot of noise, which can have a significant impact on some marine animals. For this reason, planners should include noise mitigation measures when selecting the site for the future wind farm. The end of a wind turbine’s service life is not a major environmental issue. Most components of a wind turbine can be easily recycled and the biggest challenge is the rotor blades due to the composite materials used.

Valorization of marble sludge waste in biodiesel production using a central composite design.

This work addresses the scarcity of energy resources and environmental issues by concentrating on the synthesis of biodiesel by the transesterification of waste cooking oil with methanol. Marble sludge (MS), a novel heterogeneous catalyst, was used to speed up the rate of reaction. The catalyst's physical and chemical characteristics were thoroughly examined using a variety of methods, including X-ray diffraction, X-ray Fluorescence, SEM, particle size distribution, and BET analysis. Using the MS catalyst, the study investigated the impact of important parameters on the yield of biodiesel from waste cooking oil with the aid of response surface methodology using Design-Expert version 13 software. These parameters included temperature (50-70℃), reaction time (1-4h), catalyst concentration (1-5 wt%), and methanol-to-oil molar ratio (5-20mol/mol). Optimization of the parameters was performed for economic targets to lower the production cost of biodiesel. The results showed that a methanol-to-oil molar ratio of 20:1, a catalyst of 5 wt%, and a reaction time of 1h at 57℃ were the ideal parameters for obtaining a biodiesel yield of 93.5%. The resultant biodiesel revealed promising characteristics, such as a flash point of 160℃, a kinematic viscosity of 4 mm2/s, and a density of 0.871g/cm3. The study demonstrates the significant consequences and real-world advantages of using rational engineering methods to use MS as a very effective, stable, and easily recoverable catalyst for the long-term, sustainable generation of biodiesel from waste cooking oil.

Products Distribution and Reaction Kinetics from Co-Pyrolysis of Pinewood and Polypropylene under Non-Catalytic and Catalytic Reaction Conditions

Abstract Co-pyrolysis technology offers vital pathways for efficient utilization of plastics and biomass resources to help reduce the environmental problems and energy resources issues. The pyrolysis characteristics of pinewood and polypropylene (PP) mixtures were analyzed using TGA. The results showed a decrease in first peak of the mixture with increase in PP in the mixture, while the second peak increased with an increase in PP in the mixture. The addition of a catalyst decreased the DTG peak heights. The reduction in the first peak with different catalysts was in the order: CaO/ZSM-5 >CaO >ZSM-5, while for the second peak showed: CaO >CaO/ZSM-5 >ZSM-5. The activation energy, calculated by Flynn–Wall–Ozawa (FWO), Kissinger–Akahira–Sunose (KAS), and Friedman models, revealed that ZSM-5 reduced the activation energy, whereas CaO/ZSM-5 increased the activation energy, as compared to no catalyst case. Increase of co-pyrolysis temperature reduced the yield of aldehydes, ketones, acids and esters, but increased the yield of hydrocarbons. The addition of CaO reduced the yield of ketones, phenols, esters, and acids, while it increased the yield of alcohols. The addition of ZSM-5 also decreased the yield of ketones, phenols, acids and hydrocarbons, but increased the yield of furans and alcohols. The addition of CaO/ZSM-5 specifically reduced the yield of aldehydes and alcohols. The results show the important role of the specific catalysts examined on the resulting products distribution for the same reaction condition.

UTILIZATION OF CASSAVA PEEL AND CHITOSAN FOR THE PRODUCTION OF HYDROGEL AS A SUSTAINABLE SOLUTION FOR DOMESTIC WASTEWATER TREATMENT

Water pollution is a significant environmental issue, especially in developing countries where domestic wastewater often contains a high concentration of pollutants, posing risks to public health and the environment. Hydrogel from cassava peel and chitosan shows promise as a bioadsorbent for domestic wastewater treatment, but its capacity and optimal production temperature have not been fully studied. The study aimed to investigate the characteristics of hydrogel from cassava peel and chitosan, the optimal temperature for hydrogel production, and the efficacy of hydrogel as a bioadsorbent for domestic wastewater treatment. The study involved four stages: cellulose isolation, hydrogel preparation, wastewater treatment experimentation, and data analysis. The results showed that chitosan hydrogel synthesized at 750C had superior efficiency, achieving an optimal outcome of 88% in the treatment of household wastewater using a triad of chitosan hydrogel pellets. The degree of cross-linking in chitosan hydrogel diminished with an increase in heating temperature

Towards Sustainable Construction: Evaluating Thermal Conductivity in Advanced Foam Concrete Mixtures

Traditional concrete structures are frequently linked to poor energy efficiency and substantial heat loss, which pose significant environmental issues. To enhance thermal insulation and reduce heat loss, the use of precast insulated walls is suggested. This research introduces a new energy-efficient precast concrete panel (PCP). We explored various material combinations, including air bubbles, nano microsilica compound (NMC), nano microsilica powder (NMP), and latex, to determine the most effective formulation. A total of 99 tests were performed to assess the compressive strength of the samples, with 28 tests selected for thermal conductivity evaluations at temperatures of 300 °C and 400 °C based on satisfactory compressive strength results. The results indicated that the optimal mix of 4% air bubbles and 13% NMC achieved the lowest thermal conductivities of 1.31 W/m·K and 1.20 W/m·K at 300 °C and 400 °C, respectively, showing improvement ratios of 7% and 15.5% compared to the baseline tests. Additionally, the tests that included latex did not meet the thermal conductivity standards. The optimal combinations identified in this research can be effectively utilized in PCPs, resulting in significant energy savings. It is expected that stakeholders in the green building sector will recognize these proposed PCPs as a practical energy-efficient solution to advance sustainable and environmentally friendly construction practices.

The role of marine bacteria in modulating the environmental impact of heavy metals, microplastics, and pesticides: a comprehensive review.

Bacteria assume a pivotal role in mitigating environmental issues associated with heavy metals, microplastics, and pesticides. Within the domain of heavy metals, bacteria exhibit a wide range of processes for bioremediation, encompassing biosorption, bioaccumulation, and biotransformation. Toxigenic metal ions can be effectively sequestered, transformed, and immobilized, hence reducing their adverse environmental effects. Furthermore, bacteria are increasingly recognized as significant contributors to the process of biodegradation of microplastics, which are becoming increasingly prevalent as contaminants in marine environments. These microbial communities play a crucial role in the colonization, depolymerization, and assimilation processes of microplastic polymers, hence contributing to their eventual mineralization. In the realm of pesticides, bacteria play a significant role in the advancement of environmentally sustainable biopesticides and the biodegradation of synthetic pesticides, thereby mitigating their environmentally persistent nature and associated detrimental effects. Gaining a comprehensive understanding of the intricate dynamics between bacteria and anthropogenic contaminants is of paramount importance in the pursuit of technologically advanced and environmentally sustainable management approaches.

The effects of conflicting economic and environmental goals on local governments’ responses to citizens’ complaints: evidence from China

PurposeThe paper examines how local governments’ responses to citizens’ complaints about environment issues are affected when the complaints involve conflicting goals, particularly economic versus environmental goals. This study focuses on the responsiveness of provincial governments to citizen environmental complaints on the Local Leader Message Board (LLMB) in China.Design/methodology/approachThis study collected 125,364 environment-related complaints lodged by citizens on the LLMB from 2013 to 2021 and identified complaints embodying conflicting goals through a Structural Topic Model (STM). Advanced supervised machine learning (ML) algorithms were employed to enhance the robustness of the findings.FindingsThe results indicate that provincial governments prioritize citizens’ complaints across different types of issues. However, complaints embodying conflicting goals (related to environmental issues) are less likely to get a response. This relationship is moderated by an inverted U-shaped effect of economic dependence on industries. This suggests that the impact of conflicting goals on government responsiveness is dynamic, with the likelihood of provincial governments responding to conflicting complaints initially increasing and then decreasing as economic dependence on industries rises.Originality/valueThe findings enrich the understanding of the consequences of conflicting goals by highlighting their potential as a mechanism to explain the strategic reactions of governments to citizens.

Harnessing genomic technologies for one health solutions in the tropics.

The targeted application of cutting-edge high-throughput molecular data technologies provides an enormous opportunity to address key health, economic and environmental issues in the tropics within the One Health framework. The Earth's tropical regions are projected to contain > 50% of the world's population by 2050 coupled with 80% of its biodiversity however these regions are relatively less developed economically, with agricultural productivity substantially lower than temperate zones, a large percentage of its population having limited health care options and much of its biodiversity understudied and undescribed. The generation of high-throughput molecular data and bespoke bioinformatics capability to address these unique challenges offers an enormous opportunity for people living in the tropics. MAIN: In this review we discuss in depth solutions to challenges to populations living in tropical zones across three critical One Health areas: human health, biodiversity and food production. This review will examine how some of the challenges in the tropics can be addressed through the targeted application of advanced omics and bioinformatics and will discuss how local populations can embrace these technologies through strategic outreach and education ensuring the benefits of the One Health approach is fully realised through local engagement. Within the context of the One Health framework, we will demonstrate how genomic technologies can be utilised to improve the overall quality of life for half the world's population.

Isu-Isu Politik dalam Kampanye Calon Presiden RI terhadap Preferensi Pemilih di Nusa Tenggara Barat

This study examines the preferences of voters in West Nusa Tenggara (NTB) in the context of the 2024 Indonesian presidential election and how various political issues influence their choices. Utilizing a quantitative approach and descriptive survey, data was collected from 2,672 respondents representing diverse educational and occupational backgrounds in the NTB region. The findings reveal various political issues affecting voter preferences, including economic, social, environmental, security, leadership, and other issues. The most dominant issue in NTB voters' preferences is Nationalist Religious Issues, with about 24% of respondents considering it the most important issue. Socialism and Cultural Issues also receive significant attention, reflecting concern for the preservation of local culture and social integration. Additionally, Education and Public Health Issues are high priorities for NTB voters, indicating the need for access to quality education and good healthcare services. This research provides a deeper understanding of the political dynamics in NTB and the factors influencing voter decisions. The results can guide presidential candidates and political parties in designing campaign platforms relevant to the needs of this region. Furthermore, this study can help enhance political participation, advance important issues, and strengthen political representation at the local level. Recommendations are given for further studies on the role of religion in NTB politics, evaluation of issue fulfillment in public policy, analysis of demographic changes, and studies on political participation in NTB. This research is expected to provide valuable contributions to understanding regional politics in Indonesia and voter preferences that could influence the outcome of the 2024 presidential election in NTB.

Economic Performance: Impact of Implementing Environment Cost and Disclosure Carbon Emissions Fiqh Al Bi'ah (Environment) Analysis Approach

The development of environmental issues is of concern to the public in encouraging companies' awareness to carry out environmental management in their business activities, where companies can plan environmental cost budgets and make disclosures of the impact of carbon emissions produced in order to achieve their goal, namely the sustainability of the Company, namely the Company's economic performance will increase. This research aims to see the impact of environmental costs and carbon emission disruption on economic performance and is analyzed using environmental fiqh (bi'ah). This research is quantitative research. The type of data used is secondary data obtained from the Company's official website. The population in this study are manufacturing companies listed on the Jakarta Islamic Index for 2019-2021. The research sample consisted of 8 companies from the 2019-2021 period, totaling 32 samples. The sampling technique used in this research was purposive sampling. The data analysis used is panel data regression analysis using the SEM PLS data modeling program. The results of the research show that environmental cost and carbon emission disclosure variables have a significant negative influence on economic performance and the results of environmental fiqh (al bi'ah) analysis are in accordance with the verses of the Koran which discuss environmental damage which is something that is absolutely not justified because it will bring negative impact on the sustainability of living creatures or organizations and companies. These limitations suggest that future research could expand the sample size, consider a wider range of sustainability practices, and explore the relevance of environmental performance in different cultural and industry contexts.

Pro-environmental behavior to improve the quality of life withsocial value orientation as moderator: findings from Indonesia

ABSTRACT Environmental degradation endangers human life. Future generations will be at risk if the necessary impact is not immediately addressed. Addressing environmental issues and enhancing quality-of-life (QoL) require pro-environmental behavior. This study aimed to examine the moderating role of social-value-orientation (SVO) in the association between pro-environmental behavior and QoL. Conducting in Indonesia and involving 402 students i.e., 303 female-students (Mages = 20.48 years, SD = 1.42) and 99 male-students (Mages = 20.49 years, SD = 1.42), this study used General Ecological Behavior Scale (α = 0.83), the WHOQOL-BREF (α = 0.87), and the triple-dominance of SVO. JASP 0.17.2.1 was performed to analyse data namely descriptive statistics and testing the moderating effect. The results showed that pro-environmental behavior and SVO predicted QoL (R2 = 0.247, F(3.398) = 45.533, p = 0.001), SVO moderated the association between pro-environmental behavior and QoL significantly (β = 0.141, p = 0.002). These findings have important implications for the sustainable behavior’s promotion and the QoL’s improvement.

Disaggregating air, water and renewable energy disclosures in developing economies: the role of regulatory impact and board characteristics

PurposeThis study examines how board characteristics influence air, water and renewable energy (AWR) disclosures in an emerging economy. It argues for the necessity of separating these disclosures to address unique environmental impacts and stakeholder concerns.Design/methodology/approachUsing longitudinal data from environmentally sensitive firms (2014–2022), a disclosure index based on the Global Reporting Initiative (GRI) framework was developed to quantify AWR separately. To address potential statistical issues such as endogeneity and selection bias, the analysis employed a set of robust regression models, including the industry fixed effects (FE) model, a lagged model and a two-stage least squares (2SLS) model.FindingsBoard size and audit committees positively influence all AWR disclosures, while foreign directors significantly impact air and renewable energy disclosures. Board meetings negatively affect water disclosures. Surprisingly, board independence shows no significant impact, and gender diversity has no notable relationship. Post-amendment, firms increased AWR disclosures, though participation remains limited.Research limitations/implicationsGrounded in legitimacy theory, this study contributes to the literature by demonstrating how separating the unique characteristics of AWR disclosures offers stakeholders more precise insights into how firms manage specific environmental concerns. The findings are based on data from listed firms in Bangladesh and may not be generalisable to unlisted firms or other regions.Practical implicationsThe study emphasises the importance of distinct AWR reporting, offering valuable insights for regulators and corporate boards to improve transparency and sustainability practices.Social implicationsSeparating AWR disclosures provides stakeholders with clearer assessments of firms' environmental performance, promoting accountability and informed decision-making.Originality/valueThis study uniquely emphasises the need for disaggregating air, water and renewable energy disclosures in emerging economies. By focussing on each environmental issue separately, the research highlights how distinct disclosures offer clearer insights into how firms address specific environmental challenges, such as air pollution, water management and the transition to renewable energy sources. This disaggregation is essential for stakeholders – particularly regulators, investors and policymakers – to assess and respond to firms' sustainability efforts accurately.

Adverse outcome pathway of Alzheimer's Disease-like changes resulting from autophagy flux blockade after MC-LR exposure.

Microcystins (MCs) pollution is a worldwide environmental issue concerning about human health. Microcystin-leucine-arginine (MC-LR), the most common type of MCs produced by cyanobacteria, could enter the brain and bring about damage to the nervous system. Up to date, it is not clear about the mechanism of MC-LR-induced neurotoxicity. Amyloid-β (Aβ) deposits are hallmark of Alzheimer's disease (AD). In this study, we revealed that MC-LR exposure at environment-related doses (1, 7.5, 15 μg/L) could promote Aβ accumulation in mouse brain. Mechanismly, we firstly found that Aβ accumulation is closely associated with abnormal Aβ degradation due to autophagy flux blockade and lysosome dysfunctions in neurons after MC-LR exposure. Moreover, an adverse outcome pathway (AOP) framework oriented to neurotoxicity of MC-LR was conducted in this study. MC-LR inhibited the activity of protein phosphatase 2A (PP2A) in neurons, which is regarded as a molecular initiating event (MIE). In addition, the abnormalities in autophagy were observed after MC-LR exposure. The hindered autophagosome-lysosome fusion and disrupted lysosomal function were key events (KEs) after MC-LR exposure, which contributed to proteostasis dysregulation, ultimately leading to Aβ abnormal degradation and learning deficits as adverse outcomes (AO) of neurotoxicity. This study provided novel information about MC-LR neurotoxicity and new insights into understanding the mechanisms underlying the environmental chemicals-induced neurodegeneration diseases, which has deep implications for public health.