The outbreak of coronavirus disease 2019 (COVID-19) has led to an increase in infectious medical waste (IMW). Waste-to-energy (WtE) technologies are considered to manage IMW in the context of the COVID-19 situation and to reduce illegal dumping and landfill problems. This study focuses on managing IMW by using WtE technology. Energy, economic, and environmental (3E) impacts are considered as a single implication value of WtE technology. Combined cooling, heating, and power (CCHP) is a novel system for generating energy from a treated IMW by using a steam sterilization system. The moisture from sterilization waste is extracted by a drying process to create refuse-derived fuel type 3 (RDF-3). An RDF-3 of 81.98 kg/h at a low heating value of 26.29 MJ/kg is used for a combustion–incineration process of 236.56 kW. A net power from an organic Rankine cycle of 15.80 kWe, an absorption cooling capacity of 4.62 kW, and a drying room unit of 13.21 kW are found from the combined CCHP system. The energy index is calculated at an overall energy efficiency of approximately 13.40 %. The energy–environmental impact is summarized by a single score of 5.63E-04 Pt. The energy–economic impact is summarized by a levelized energy cost of 0.35 USD/kWh. The economic-environmental perspective is an energy costing per life cycle assessment of 0.73 USD/kg emission-eq. The 3E analysis reveals a single indicator of 1.95E-04 USD·Pt/kWh2, which is used in the decision to compare with other energy systems. The CCHP system shows advantages in terms of sustainability, quality, and efficiency. Consequently, a novel in this study promotes the sustainability of energy, avoiding environmental impact, and IMW management.
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