ABSTRACT The harsh indoor environment in winter in the hot-summer and cold-winter zones of China and the increasing demand for winter heating from residential consumers have prompted more and more researchers to address the energy-efficient heating problem in non-centralized heating areas. A computational fluid dynamics model of a typical building was developed to analyze the dynamic heat transfer characteristics and energy consumption of interior partitions under decentralized heating in this region, of which the accuracy of the established model was proved by the relative error of less than 5% compared with the experimental measurement. Then seven typical kinds of interior partition configurations with different wall thickness, wall material, and insulation layer locations were developed and evaluated through simulation analysis. Transient heat storage ratio and cumulative heat storage ratio were proposed to demonstrate the dynamic heat transfer characteristics of interior partitions. The simulation results showed that 180 mm and 220 mm solid clay bricks can reduce energy consumption by 17.56% and 30.23%, respectively, compared with 120 mm solid clay bricks. The energy consumption of fly ash aerated concrete and solid clay brick partitions were reduced by 10.18% and 19.02%, respectively, compared with porous concrete partitions. The dynamic heat transfer characteristics of internal partitions with internal insulation were similar to those with external insulation due to the reduction in unnecessary energy consumption transferred to adjacent unheated rooms by about 20% compared to that without insulation. And the heat consumption of interior partitions under convective heating was 17.3% higher than under radiant heating.