In this work, we investigate colloidal particle patterns as a possible noise source for random number generation. We systematically analyze the minimum entropy of the noise source over different particle concentrations of {1, 3, 5, 7, 10, 12, 15} mg/ml according to the recommendations of the National Institute of Standards and Technology Special Publication 800-90B. The estimated minimum entropy of the non-independent and identically distributed particle pattern noise source is Hmin = 0.5896/1 bit at a particle amount of 5 mg/ml. For further entropy extraction on the noise source data, the secure hash algorithm is used to construct an entropy source. The randomness of the derived entropy source is verified according to the National Institute of Standards and Technology Special Publication 800-22 Rev. 1a and the accompanying statistical test suite. The entropy source passes all randomness tests of the statistical test suite and shows an estimated minimum entropy of Hmin = 0.9992/1 bit.
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