Parenteral Nutrition Research Articles

THRIVE-1: A multi-center, cross-sectional, observational study to assess the prevalence of choline deficiency in patients dependent on parenteral nutrition

THRIVE-1: A multi-center, cross-sectional, observational study to assess the prevalence of choline deficiency in patients dependent on parenteral nutrition

Does parenteral nutrition with amino acids in fasting patients with aspiration pneumonia affect acute prognosis?

Does parenteral nutrition with amino acids in fasting patients with aspiration pneumonia affect acute prognosis?

Parenteral nutrition in advanced cancer: a qualitative study on decision-making and information needs of patients and carers

Parenteral nutrition in advanced cancer: a qualitative study on decision-making and information needs of patients and carers

Опыт лечения пораженных при аварии на Чернобыльской АЭС в условиях специализированного стационара

Summary. The purpose of the study is to analyze and summarize the experience of treating those affected by a radiation accident at the Chernobyl nuclear power plant (Chernobyl nuclear power plant) in a specialized hospital. Materials and research methods. The research materials are documented experience in organizing treatment and treating those injured in the Chernobyl accident with acute radiation injury. Research methods – analytical method and method of generalization. The results of the study and their analysis. 129 patients were sent to a specialized hospital in Moscow in the first two days, 84 of which were diagnosed with acute radiation disease (OLB) II-IV Art. severity. As the main diagnostic criteria for the early diagnosis of patients used: the timing and severity of the primary general and local (leather) reaction, the severity of lymphopenia and neutrophilic leukocytosis and other criteria. The main directions of early treatment of the affected were: – prevention and treatment of infectious complications; – detoxification therapy; – correction of water-electrolyte metabolism, parenteral nutrition in connection with common burns, oropharyngeal syndrome, intestinal syndrome, etc.; – pre-transplantation: HLA-typification of patients, the selection of donors, the actual transplantation of bone marrow from the donors of relatives and cells of the embryonic human liver (in the absence of donors) affected with irreversible damage to the bone marrow; – replacing therapy with blood cells. Based on the results of the study, the following conclusions were made: – the complex of medical measures was highly effective; – there were practically no fatal outcomes due only to infection in patients with bone marrow, even severe and extremely severe, form of OLB, not complicated by burns, radial enteritis or acute secondary disease due to bone marrow transplantation; – none of the patients died from hemorrhagic syndrome, most had no signs of bleeding even with deep and prolonged thrombocytopenia (> 2–4 weeks); – the successful treatment of those affected in the Chernobyl accident was prepared by many years of experience in the work of the Clinical Division of Radiation Medicine of the Institute of Biophysics of the USSR Ministry of Health – State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency for the treatment of those affected in other radiation accidents.

Percentage of patients using parenteral nutrition who have had a primary bloodstream infection – should this condition alert care teams?

Percentage of patients using parenteral nutrition who have had a primary bloodstream infection – should this condition alert care teams?

Nutritional status and cannula infections in pediatric patients on ventricular assist device support.

Ventricular assist devices (VADs) are used to bridge pediatric patients to heart transplantation. Paracorporeal VADs require the placement of cannulas, which can create an environment for infections. We examined cannula infections in pediatric VAD patients and the role of nutritional status. This retrospective study (2005-2021) included patients <20 years old on VAD support using Berlin Heart EXCOR® cannulas. Cannula infections were defined by a positive culture and need for antibiotic therapy. Malnutrition was defined using the American Society of Parenteral and Enteral Nutrition guidelines as well as the Michigan MTool. There were 76 patients with a median age at implant of 0.9 years (IQR 0.4, 3.6), 50% male, with 73.7% having non-congenital heart disease. More than one-quarter (26.3%) of patients developed a cannula infection. Higher pre-implant weight (OR = 1.93, p = 0.05), creatinine (OR = 1.02, p = 0.044), and pre-albumin (OR = 15.79, p = 0.025), as well as duration of VAD support (OR = 1.01; p = 0.003) were associated with increased odds of developing a cannula infection. There was no difference in the malnutrition parameters between those with and without an infection. Further exploration in a larger cohort is needed to see whether these associations remain and if the incorporation of objective measures of nutritional status at the time of infection are predictive.

Healthy sleep practices for consumers of home total parenteral nutrition: A mixed-methods community-based participatory study

Healthy sleep practices for consumers of home total parenteral nutrition: A mixed-methods community-based participatory study

S1117 Outcomes of Total Parental Nutrition in Inflammatory Bowel Disease: A Nationwide Inpatient Sample

S1117 Outcomes of Total Parental Nutrition in Inflammatory Bowel Disease: A Nationwide Inpatient Sample

S1937 Patterns and Predictors of Outcomes in Total Parenteral Nutrition Associated Liver Disease

S1937 Patterns and Predictors of Outcomes in Total Parenteral Nutrition Associated Liver Disease

The roll of glutamine and zinc additioned to total parenteral nutrition in the outcome of pacients with oral mucositis grade III and IV. Case report.

The roll of glutamine and zinc additioned to total parenteral nutrition in the outcome of pacients with oral mucositis grade III and IV. Case report.

Umbilical Catheter Extravasation Mimicking Necrotizing Enterocolitis in a Preterm Neonate: A Diagnostic Challenge.

Managing acute abdomen in very low birth weight (VLBW) and premature infants presents a diagnostic challenge, often necessitating a thorough assessment to discern underlying causes. Umbilical venous catheters (UVCs), commonly used in neonatal intensive care, are essential but not without risks. A 29-week premature male infant, born to a 23-year-old mother, was referred to our clinic on the 16th day of life with a suspected diagnosis of necrotizing enterocolitis (NEC). The infant had spent the first day intubated and received non-invasive respiratory support for 15 days. A 5 French UVC was inserted at the 2nd hour of life, and by the 3rd day of life, the infant transitioned to minimal enteral feeding. Between the 12th and 16th days of life, the infant initially diagnosed with NEC due to symptoms such as decreased stool passage and abdominal distension. The patient had been on a continuous course of antibiotic treatment throughout the entirety of his life, commencing on the very first day due to suspected early neonatal sepsis, followed by nosocomial sepsis during the hospitalization, and persisting with antibiotic therapy for suspected NEC. The case took a unique turn upon further evaluation after being referred to our unit. Despite a preliminary NEC diagnosis, further evaluation revealed umbilical catheter complications, leading to total parenteral nutrition extravasation. Removal of the catheter, drainage, and antibiotic adjustment resulted in improved clinical outcomes. In neonatal care, cautious management is vital when dealing with infants exhibiting abdominal symptoms. A nuanced approach, including differential diagnosis and careful antibiotic use, is essential.

Virtual reality for central catheter care training in patients on home parenteral nutrition: Description and preliminary data of the usefulness of the tool

Virtual reality for central catheter care training in patients on home parenteral nutrition: Description and preliminary data of the usefulness of the tool

Unveiling catheter related bloodstream infection rates in inpatient parenteral nutrition: A call for action

Unveiling catheter related bloodstream infection rates in inpatient parenteral nutrition: A call for action

Evaluation of parenteral nutrition treatment in hematological oncology patients in terms of appropriateness with ESPEN Guideline and pharmacoeconomics

Evaluation of parenteral nutrition treatment in hematological oncology patients in terms of appropriateness with ESPEN Guideline and pharmacoeconomics

Review of parenteral nutrition prescription in cancer patients in a comprehensive cancer centrE

Review of parenteral nutrition prescription in cancer patients in a comprehensive cancer centrE

Parenteral nutrition infusion has no clinical implications for bioelectrical impedance measurements in chronic intestinal failure patients.

Parenteral nutrition infusion has no clinical implications for bioelectrical impedance measurements in chronic intestinal failure patients.

The usefulness of intravenous lipid emulsion in postoperative nutritional management-proposal for the novel concept “intermediate parenteral nutrition”-

The usefulness of intravenous lipid emulsion in postoperative nutritional management-proposal for the novel concept “intermediate parenteral nutrition”-

Impact of Glutamine-Enhanced Parenteral Nutrition on Postoperative Outcomes in Colorectal Cancer Patients.

This study investigated the effects of parenteral glutamine (Gln) supplement immunonutrition versus conventional nutritional support on postoperative Clavien-Dindo classification complications and recovery, perioperative nutritional status, and immune, inflammation, and safety indicators in patients with colorectal cancer (CRC). Clinical data were collected for a retrospective cohort study of 178 patients (58 and 120 patients in the observation and control groups, respectively) who underwent radical resection of CRC from January 2019 to December 2021. The incidence of postoperative complications was calculated. Postoperative recovery, nutritional indicators, inflammatory factors indicator, and the safety indicators before operation and at 1, 3, and 7 days after operation were compared. SPSS 29.0 statistical software was used for statistical analysis. The incidence of postoperative overall complications in the control group and the observation group was 22.50% (27/120) and 17.24% (10/58), respectively, and there was no significant difference between the two groups (P=0.42). The incidence of postoperative complications of Clavien-Dindo grade ≥III in the control group and the observation group was 14.17% (17/120) and 3.45% (2/58), respectively, and the difference between the two groups was statistically significant (P=0.03). Secondary outcomes (first exhaust, defecation, and liquid diet intake times) were significantly recovered earlier in the observation group than those in the control group (P<0.05), while the postoperative hospital stay was significantly shorter(P=0.04). The perioperative nutritional status did not significantly differ between the groups before and after surgery(P>0.05), although significant differences were observed in several inflammatory and safety indicators(P<0.05). Unlike conventional nutritional support, postoperative parenteral Gln supplementation reduced the incidence of postoperative Clavien-Dindo complications grade ≥III in patients with CRC while increasing intestinal and immune functions, decreasing inflammation, and reducing the length of hospital stay.

Stability of lipids in parenteral nutrition products admixed with nano-iron medicinal drugs

Stability of lipids in parenteral nutrition products admixed with nano-iron medicinal drugs

Impact analysis ofhome parenteral nutrition program at Prince Sultan military medical city

Impact analysis ofhome parenteral nutrition program at Prince Sultan military medical city