Fire risk assessment is an important part of fire science and system safety engineering. “FRAME” means Fire Risk Assessment Method for Engineering. It is a widely used and comprehensive building fire risk assessment method based on a fixed index system, and compared with other methods, FRAME method can avoid artificial subjective influence, and it is more convincing. The paper discusses the advantages and calculation methods of FRAME, and takes a commercial building in Shijiazhuang as an example. By using the method, the fire risk of the building is evaluated and the strengthened fire protection measures are proposed based on the method.