Energy Expenditure In Individuals Research Articles

Absence of a sexual dimorphism in postprandial glucose metabolism after administration of a balanced mixed meal in healthy young volunteers

Background/ObjectivesA different ability to regulate glucose homeostasis between men and women may contribute to their difference in diabetes prevalence and in its predisposing conditions. Data on this issue are controversial because of heterogeneous protocols and insufficient control of confounders affecting glucose metabolism like age, body composition, and physical activity level. To clarify this issue, we compared among sexes the postprandial glucose metabolism after the administration of a balanced mixed meal normalized to daily energy expenditure.Subjects/MethodsThirty-six healthy young volunteers (18 men and 18 women; age, 23.9 ± 2.8 years; BMI, 21.9 ± 1.7 kg/m2) were recruited for the experiment. After overnight fast, subjects consumed a mixed meal providing 40% of daily energy expenditure (60% carbohydrates, 25% lipids, 15% proteins) estimated multiplying resting energy expenditure, obtained by Harris & Benedict equation, for the corresponding physical activity level. Blood was sampled at 0, 10, 20, 30, 45, 60, 90, 120, and 180 min and serum concentrations of glucose, insulin, and C-peptide were measured.ResultsFasting serum glucose concentrations were lower in women than in men, while fasting insulin and C-peptide concentrations did not differ between sexes. Linear mixed models did not show any significant effect of sex and sex # time interaction on postprandial serum glucose, insulin, and C-peptide concentrations. The comparison of areas under the curve between the sexes revealed similar glycemic, insulinemic, and C-peptide postprandial responses between men and women.ConclusionsOur results do not support the hypothesis of a sexual dimorphism in the regulation of carbohydrate metabolism in young when a mixed meal normalized on individual daily energy expenditure is ingested.

The Effect of Meal Timing and Caffeine Intake on Energy Expenditure, Substrate Use and Exercise Efficiency in Healthy Male Individuals

The Effect of Meal Timing and Caffeine Intake on Energy Expenditure, Substrate Use and Exercise Efficiency in Healthy Male Individuals

Carry‐over effects of larval food stress on adult energetics and life history in a nectar‐feeding butterfly

Abstract Stressful juvenile developmental conditions can affect performance and fitness later in life. In holometabolous insects such as butterflies, development under stressful conditions may lead to smaller adult size, lower reproductive output, and shorter lifespan. However, how larval developmental stress affects energy intake and expenditure in adult individuals is poorly understood. We subjected last‐instar larvae of Speyeria mormonia Edwards (Lepidoptera: Nymphalidae) to periodic dietary restriction (DR) to examine the allocation of energy and nutrients among different life history processes. We measured adult food intake, resting metabolic rate (RMR), metabolic flight capacity, lifespan, and reproductive output. Consistent with pressure to disperse from a poor environment while maintaining offspring number, we predicted that stressed individuals would have increased adult food intake and higher flight capacity. Adult body size was strongly reduced. Contrary to predictions, we found no compensatory adult feeding. Mass‐adjusted flight metabolic rate was reduced, suggesting poor dispersal capacity. Larval DR did not affect adult lifespan, nor did the rate of metabolic senescence change. Larval DR did affect RMR, as stressed females had a steeper slope between RMR and body mass, which may reflect differences in physiological activity due to condition. Fecundity decreased less than predicted based on body mass. Instead of investing in flight capacity, females increased relative allocation to reproduction, which may partly buffer against poor environmental conditions. Understanding the interplay of energy acquisition and allocation to life history traits across the life cycle is vital for predicting responses to environmental change.

Effect of Walking Speed on Gait Parameters and Energy Expenditure in Individuals with Unilateral Trans-tibial Amputatio

Background and Objectives: Analysis of gait parameters and energy expenditure in different walking speeds in trans-tibial amputees has been less investigated. This may provide an insight into how they respond to it. The main aim of this study was to investigate the effect of walking speed changes on gait parameters and metabolic energy consumption in unilateral trans-tibial amputees using the prosthesis. Methods: Thirty trans-tibial amputees fulfilling inclusion criteria were investigated for gait parameters using a ten-meter walk test while these subjects walked with three different walking speeds (comfortable, fast, and slow). Temporal-spatial gait parameters, such as step length, stride length, velocity and cadence, and Physiological Cost Index (PCI) for metabolic energy consumption were analyzed by repeated-measures ANOVA. Results: Step length of a prosthetic side in the fast walking speed (0.67±0.10 m) was higher than the normal comfortable speed (0.56±0.13 m) and least in slow walking (0.42±0.06 m). A similar trend was observed for all gait parameters. PCI (beats/m) was least in normal comfortable speed (0.08±0.09), followed by fast walking speed (0.11±0.08). It was highest when patients walked at a slow speed (0.18±0.12). There was a significant difference in all temporal-spatial gait parameters and PCI in three walking speed conditions (p<0.05). Conclusion: Walking speed significantly affected all temporal-spatial and energy parameters in unilateral trans-tibial amputees.

A comparison of accelerometer cut-points for measuring physical activity and sedentary time in adolescents with Down syndrome

BackgroundNo cut-points have been developed for youth with Down syndrome; there is concern that altered gait patterns, decreased energy expenditure and exercise capacity of individuals with Down syndrome may produce inaccurate physical activity data if accelerometer data are analyzed using cut-points from populations with typical development and other IDD diagnoses. AimTo compare physical activity and sedentary time across existing accelerometer cut-point methods in adolescents with Down syndrome. MethodsIn this cross-sectional analysis, participants diagnosed with Down syndrome (n = 37; 15.5 ± 1.9 years; 57 % female) wore an accelerometer on their non-dominant hip for seven-days. Data were analyzed and compared across four physical activity intensity cut-points: Evenson, Freedson 4-MET, McGarty, and Romanizi. Outcomes & resultsDifferences in time spent in each intensity across cut-point methods were evident for sedentary (448−615 min/day), light (72−303 min/day) and moderate-to-vigorous (12−77 min/day) activities. Between 0.0–67.6 % of the sample met the physical activity guidelines, depending on the cut-point method selected. Conclusions & implicationsThis study presents the wide variation of accumulated physical activity minutes when different cut-points are applied to individuals with Down syndrome. There is a critical need to establish Down syndrome-specific measures of physical activity assessment rather than applying methods developed for their peers with typical development. What this paper addsThis paper highlights concerns over the application of objective measurements of physical activity in youth with Down syndrome from measurement methods derived from populations with typical development. This is the first manuscript to examine this issue in a sample comprised solely of youth with Down syndrome. Results demonstrate the large variation in time spent in each activity intensity that arise due to the application of different cut-point methods.

Relationship Between Heart Rate, Oxygen Consumption, and Energy Expenditure in Futsal.

The primary aim of this study was to compare the measured oxygen consumption (Measured-VO2) in a simulated futsal game (S-Game) with the estimated oxygen consumption (Estimated-VO2) through a regression equation between heart rate (HR) and oxygen consumption (VO2) (HR-VO2) in treadmill running, and a secondary aim was to calculate the total energy expenditure (EE) in S-Game. Ten professional players (22.20 ± 3.22 years) were evaluated. HR-VO2 was determined individually in the continuous test on the treadmill (ContTest). The Measured-VO2 in S-Game was compared with the Estimated-VO2 in the ContTest. Alactic and lactic pathways were estimated by VO2. The Estimated-VO2 presented no statistically significant difference with the Measured-VO2, using the paired t-test (p = 0.38). However, the correlation between Estimated- and Measured-VO2 was very weak (r = −0.05), and it presented poor agreement (concordance correlation coefficient = −0.04). In addition, a Bland–Altman plot presented bias of −2.8 ml/kg/min and individual difference as large as 19 ml/kg/min. The HR-VO2 determined by the ContTest was not a good individual predictor of VO2. The high intensity and intermittent nature of the futsal game possibly caused dissociation in the HR-VO2 relationship. ContTest is not recommended for estimating VO2 and calculating individual EE in the futsal game. This is recommended only for the group mean. The total EE in S-Game was 13.10 ± 1.25 kcal.min−1 (10.81 ± 1.57 metabolic equivalents). The contributions from the metabolic pathways were as follows: aerobic (93%), alactic (5%), and lactic (2%).

Inferring Whole-Organism Metabolic Rate From Red Blood Cells in Birds.

Metabolic rate is a key ecological variable that quantifies the energy expenditure needed to fuel almost all biological processes in an organism. Metabolic rates are typically measured at the whole-organism level (woMR) with protocols that can elicit stress responses due to handling and confinement, potentially biasing resulting data. Improved, non-stressful methodology would be especially valuable for measures of field metabolic rate, which quantifies the energy expenditure of free-living individuals. Recently, techniques to measure cellular metabolic rate (cMR) in mitochondria of blood cells have become available, suggesting that blood-based cMR can be a proxy of organismal aerobic performance. Aerobic metabolism actually takes place in the mitochondria. Quantifying cMR from blood samples offers several advantages such as direct estimates of metabolism and minimized disturbance of individuals. To our knowledge, the hypothesis that blood-based cMR correlates with woMR has not yet been directly tested. We measured cMR in red blood cells of captive great tits (Parus major), first during their morning activity period and second after subjecting them to a 2.5 h day-time respirometry protocol to quantify woMR. We predicted cMR to decrease as individuals transitioned from an active to a resting state. In the two blood samples we also assessed circulating corticosterone concentrations to determine the perceived disturbance of individuals. From respirometry traces we extracted initial and final woMR measures to test for a predicted positive correlation with cMR measures, while accounting for corticosterone concentrations. Indeed, cMR declined from the first to the second measurement. Furthermore, woMR and cMR were positively related in individuals that had relatively low corticosterone concentrations and displayed little locomotor activity throughout respirometry. By contrast, woMR and cMR covaried negatively in birds that increased corticosterone concentrations and activity levels substantially. Our results show that red blood cell cMR represents a proxy for woMR when birds do not display signs of stress, i.e., either before increases in hormonal or behavioral parameters have occurred or after they have abated. This method represents a valuable tool for obtaining metabolic data repeatedly and in free-living individuals. Our findings also highlight the importance of accounting for individual stress responses when measuring metabolic rate at any level.

251-OR: Impact of Vegetarian and the Nordic Diet on Glucose Metabolism: A Human Intervention Study

Background: Recent epidemiological studies indicate that the so-called ‘Nordic’ diet (rich in berries, fish and nuts) as well as a vegetarian diet improve serum glucose kinetics and, thus, reduce the risk of diabetes development compared to the ‘Western’ diet. Evidence for these effects from controlled human intervention studies is limited. Methods: One hundred and twenty overweight adults with at least 1 metabolic syndrome trait (60±7 y, BMI 31.1±3.5 kg/m2, WC men 109±9 cm, women 104±9 cm) were randomized into 3 groups, adhering to Nordic diet [ND], lacto-ovo vegetarian diet [VD], or habitual control diet [HD] for 6 weeks, based on a recipe list, which was adapted to individual energy expenditure (RMR measured by QuarkRMR device, multiplied by a factor of 1.5 for physical activity). At baseline and after 6 weeks, OGTT and mixed meal tolerance test [MMTT] (180 min; postprandial measurements at 7 time points [tp]) were performed. Statistical data analysis was conducted using linear mixed-effect models (group-specific comparison: visit*diet*tp interaction). Results: As expected no changes in body weight (p=0.083) and body composition (p=0.354) were detected. Within groups, fasting glucose (p=0.760) and insulin levels (p=0.066), HbA1c (p=0.979) and HOMA index (p=0.150) did not change after 6 weeks compared to baseline. Insulin sensitivity (Matsuda index p=0.498, OGIS p=0.478, insulinogenic index p=0.203) and ß-cell function (disposition index p=0.997) showed no intergroup variations. In the group comparison, no effect was found after OGTT and MMTT on AUC of glucose (p=0.869/p=0.824) and insulin (p=0.850/p=0.999). However, compared to controls, VD improved kidney values and ND improved blood lipids, liver and kidney values. Conclusion: Our medium-term isoenergetic intervention study did not confirm earlier results. Improvements in glucose kinetics as observed in epidemiologic studies are possibly due to a loss of body weight (hypoenergetic nutrition) independent of diet composition. Disclosure H. Huber: None. B. Stoffel-wagner: None. M. Coenen: None. L. Weinhold: None. M. Schmid: None. P. Stehle: None. M. Simon: None. Funding German Federal Ministry of Education and Research (01EA1809A)

Prolonged Glucagon Infusion Does Not Affect Energy Expenditure in Individuals with Overweight/Obesity: A Randomized Trial.

The aim of this study was to determine the effects of prolonged (72 hours) glucagon administration at a low dose (LD) (12.5 ng/kg/min) and high dose (HD) (25 ng/kg/min) on energy expenditure (EE) in healthy individuals with overweight or obesity. Thirty-one healthy participants with overweight or obesity (BMI of 27-45 kg/m2 , 26-55 years old, 23 females) were randomized into LD, HD, or placebo groups and underwent 72-hour intravenous infusion of glucagon. Whole-room calorimetry was used to assess EE and substrate use during five overnight stays (2 days at baseline, 3 days of infusion) and during two 24-hour stays (baseline vs. day 3). Blood was sampled at regular intervals throughout the inpatient stay and analyzed for glucagon and biomarkers of metabolism. HD infusion elevated plasma glucagon levels compared with the placebo and LD infusion (P < 0.001). Sleeping, basal, and 24-hour EE was not significantly different among groups at any time point. Those receiving HD had significantly higher basal fat oxidation (Fat Ox) at days 2 and 3 than those receiving the placebo (P < 0.05); however, no differences in 24-hour Fat Ox were observed among groups (baseline vs. day 3). An HD plasma glucagon infusion over 72 hours does not increase any aspects of EE in healthy individuals with overweight or obesity.

Gum chewing while walking increases walking distance and energy expenditure: A randomized, single-blind, controlled, cross-over study

Background/objectiveGum chewing while walking increases walking distance and energy expenditure in middle-aged male and female individuals. This study aimed to examine the effects of gum chewing while walking on walking distance and energy metabolism in male and female individuals of various age groups. MethodsFifty participants (25 male and 25 female individuals) aged 22–69 years completed two trials in a random order. In the gum trial, participants walked at a natural pace for 15 min while chewing two gum pellets (1.5 g, 3 kcal per pellet) following a 50-min rest period. In the tablet trial, participants rested for 50 min before walking, and the participants then walked at a natural pace for 15 min after ingesting two pellets of tablet containing the same ingredients with the exception of the gum base. The walking distance, step count, walking speed, stride, heart rate, energy expenditure, and respiratory exchange ratio were measured. ResultsWalking distance, step count, walking speed, heart rate, and energy expenditure during walking were significantly higher in the gum trial than in the tablet trial. In participants aged ≥40 years, walking distance, walking speed, stride, heart rate, and energy expenditure during walking were significantly increased during the gum trial compared with those during the tablet trial. ConclusionThe study findings demonstrated that gum chewing while walking increased walking distance and energy expenditure in both male and female individuals.

Geomechanical analysis of location and conditions for mining-induced tremors in LGOM copper mines

This paper presents the results of the statistical analyses of rock mass seismicity associated with O/ZG Rudna exploitation and geomechanical analyses concerning the location and conditions of tremor occurrences in LGOM conditions, illustrated by the example of O/ZG Rudna. As part of the statistical analyses, the assessment of rock mass seismicity formation in O/ZG Rudna throughout the whole mine area in the years 2006–2015 is presented, the results of which were the basis for subsequent geo-mechanical analyses. Within the parameters of seismic activity, the analysis covered the number of recorded events, the total value of energy emission and the index of individual energy expenditure. The presented analyses also refer to the locations of tremor source epicentres in relation to the exploitation front, distinguished into low energy and high energy tremors located ahead of the exploitation front, in the area of opening-up works and gobs. These recent results were the starting point for research and calculations on geo-mechanical analyses. These numerical calculations using the finite element method (FEM) carried out the energy density distribution of elastic deformation in the vicinity of the exploitation front. FEM calculations were designed to establish the factors and conditions that determine the location of tremor sources and the mechanism of rock destruction. Both of these factors are directly related to the magnitude of the energy emitted during the tremor. Appropriate energy measurements of elastic deformation have been adopted to determine rock mass areas which are potentially threatened by tremor occurrences of varying energy. Measures of the energy density of shear and volumetric strain enable the determination of the nature of rock mass destruction in the vicinity of mine workings, which in turn gives the basis for linking these measurements with tremor energy and location relative to the exploitation front. The results of numerical computations were compared with the results of statistical analyses on the locations of tremor sources with different energies in relation to the exploitation front in O/ZG Rudna.

Weight change adjusted equations for assessing resting metabolic rate in overweight and obese adults

BackgroundAlthough over one hundred equations have been developed to predict the energy expenditure of individuals, none are sensitive to weight change in assessment of resting metabolic rate (RMR) before and after weight loss. ObjectiveTo formulate adjusted equations for overweight and obese individuals and to compare their accuracy with existing prediction RMR equations before and after weight loss. Subjects/materialsThis is historical prospective study. Participants included 39 overweight and obese men and women before and after losing 10–20% from baseline weight on a diet and physical activity regimen for at least three months. Pre and post weight loss measured RMR results were compared to estimated RMR using several existing prediction equations: Harris and Benedict, Ravussin and Bogardus, and Mifflin et al. To improve the accuracy of these prediction equations, we suggest new equations adjusted for weight loss, based on measured RMR and evaluated their accuracy. ResultsPre and post weight loss data indicated: significant fat reduction in both genders; reduction in free-fat mass only in men, and a significant decrease in measured RMR only in women. Our suggested equations were the most accurate and closest to measured RMR in both genders, in comparison to the Harris and Benedict, Ravussin and Bogardus, and Mifflin et al equation results. Estimated RMR using the latter equations was significantly lower than measured RMR in both genders at pre and post weight loss (P < 0.01). ConclusionsThis study highlights the need for adjusting RMR equations before and after weight loss in overweight and obese individuals. Further research is needed to validate our suggested equations.

Medical high-protein nutrition therapy and loss of muscle mass in adult ICU patients: A randomized controlled trial

BACKGROUND & AIMS The degradation of muscle mass and loss of functional proteins due to catabolism are associated with adverse outcomes in critically ill patients. While an adequate supply of protein within a medical nutrition concept is suggested to minimize proteolysis, the specificities on appropriate dosage and timing are still under debate. The current study aimed to evaluate the effect of two different quantities of protein as part of a standardized energetically controlled nutrition therapy for the preservation of muscle mass in the later phase of critical illness. METHODS A randomized controlled trial was conducted in 42 critically ill patients (age 65 ± 15; 12 females; SAPS 45 ± 11; TISS 20 ± 7; SOFA-score 7 ± 3). The subjects were randomly assigned to either the intervention (1.8 g protein/kg body weight [BW]/d) or standard (1.2 g protein/kg BW/d) group. Nutrient supply via enteral and/or parenteral nutrition was calculated based on the individual energy expenditure measured by indirect calorimetry and target protein content. Quadriceps muscle layer thickness (QMLT) was observed through sonography at inclusion, and during the follow-up period, two and four weeks after inclusion. The measurement points were fixed on two sides at the midpoint and two-thirds between the anterior superior iliac spine and top of the patella. The data were analyzed descriptively wherein chi-squared tests or unpaired two-samle t-tests checked group differences. Daily changes in muscle mass were estimated using a linear mixed model. All data are shown as the mean ± standard deviation (SD). RESULTS Actual protein intake reached 1.5 ± 0.5 g and 1.0 ± 0.5 g/kg BW/d in the intervention and standard group, respectively. Mean values of all measurements of QMLT at inclusion (day 13 ± 2 after ICU admission) were 13.5 ± 7.4 mm and 13.4 ± 7.1 mm in the intervention and standard group, respectively (P = 0.967). In both the groups, QMLT decreased over time (P < 0.001), while the estimated mean values of daily QMLT changes were -0.15 ± 0.08 mm (intervention) and -0.28 ± 0.08 mm (standard) without significant between-group differences (intervention effect, P = 0.368; time x intervention effect, P = 0.242). Illness scores and clinical outcomes showed no group differences. CONCLUSION In this single-center trial the increased amounts of protein (1.5 g vs. 1.0 g/kg BW/d) provided through medical nutrition therapy in the late phase of critical illness did not achieve a statistically significant impact on the loss of muscle mass in long-term immobilized ICU patients. Larger multi-center trials are needed to evaluate whether observed numerical differences in muscle mass could be a true finding, and will translate into improved clinical outcomes. TRIAL REGISTRATION German Clinical Trials Register (http://www.drks.de/), DRKS-ID: DRKS00013594.

Sex-specific growth is mirrored in feeding rate but not moulting frequency in a sexually dimorphic snake.

Sexual size dimorphism (SSD), commonly observed in snakes, may arise from a different growth rate between the sexes. This indicates a sex-specific resource intake that is in fact observable in free-living snakes. It is not so well known whether the sexes can express differential feeding rates under conditions unconstrained by spatial accessibility, competition, etc. Here, I studied sex-specific variation in growth, its correlate-moulting frequency, and feeding rate in a captive group of sexually dimorphic banded water snakes (Nerodia fasciata) with access to food unconstrained by predation, competition or space. I showed that the sexes did indeed differ in relative mass growth in that females grew faster than males (p = 0.02), but such differences were not apparent in the moulting rate (p = 0.19). Such differential growth was mirrored in the sex-specific feeding rate, with females ingesting a larger number of meals than males (p = 0.004). Such variation in feeding rate may be governed by an individual's energy expenditure and can be interpreted as a behavioural tendency that contributes to SSD development, independently of other behavioural characteristics. Sex-specific resource demands may drive the differential effects of increasing resource scarcity on both sexes.

Analysis of adequacy of actual nutrition for athletes at training camps

An increase in special performance in elite sports requires optimization of the metabolic parameters of the organism at all stages of the annual training cycle. In this regard, it is relevant to analyze the adequacy of the actual nutrition of athletes, taking into account the energy expenditures of training loads in different seasons of the year. The aim of this study was to analyze the integral adequacy and balance of the main and essential components of the diet of athletes in different seasonal periods of the annual training cycle. Material and methods. 20 highly qualified road cyclists (the average age 22.4± 0.7 years) have been examined. Individual energy expenditures of the subjects has been determined, the actual nutrition of athletes was studied by the method of 24-hour dietary recall. In different seasons of the year, in the conditions of training camps, 1540 dietary rations of athletes have been analyzed over 5 years. The study of the energy balance and the adequacy of the actual nutrition was carried out using the developed author's automated system "FP Diet". Results. The average daily energy consumption of cyclists at different stages of the annual training cycle ranged from 4503±69 to 4646±88 kcal, which indicates that athletes belong to one of the energy-intensive sports. The calorie intake practically satisfied the average daily energy expenditures, however, the low values of the integral indicator of adequacy (43.2% for the winter-spring season and 60.0% for the summerautumn season) indicated significant imbalances in the actual diet for the main and essential nutritients, especially noticeable in the groups of vitamins and fatty acids. Against the background of insufficient consumption of vegetable oils, which causes a lack of monounsaturated fatty acids in the diet, an excessive consumption of saturated fatty acids, a deficiency of vitamins B1 and B2, a lack of vitamin C in the winter-spring period, as well as calcium and magnesium deficit have been revealed. Conclusion. The qualitative characteristics of the diet of cyclists in different seasons of the annual training session does not meet the physiological needs of the organism. Optimization of athletes' nutrition in terms of calorie content and chemical composition must be carried out taking into account the nature and methods of the training cycle, which have significant differences in the energy orientation of the loads and daily energy expenditures.

Validity of Accelerometers for the Evaluation of Energy Expenditure in Obese and Overweight Individuals: A Systematic Review.

Objective Even though the validity of accelerometers for the measurement of energy expenditure (EE) has been demonstrated for normal-weight individuals, the applicability of this instrument in obese individuals remains controversial. This review aims to summarize the level of agreement between accelerometers and the gold standards (indirect calorimetry and doubly labelled water) for the measurement of energy expenditure (EE) in obese or overweight individuals. Methods The literature search was limited to comparison studies assessing agreement in EE determination between accelerometers and indirect calorimetry (IC) or doubly labelled water (DLW). We searched in PubMed and in Scopus until March 1, 2019. The analysis was restricted to obese or overweight adult individuals. The following descriptive information was extracted for each study: sample size, characteristics of participants (sex, age, BMI, fat mass percentage, any pathological conditions, modality of recruitment in the study, and exclusion criteria), accelerometer description (model, type and body position), and type of gold standard and validity protocol (duration, conditions, and requirements during and before the experiment). Three review authors independently screened the obtained results, and the quality of the selected articles was assessed by the QUADAS-2 tool. Results We obtained seventeen eligible articles, thirteen of which showed concerns for the applicability section, due to the patient selection. Regarding the accelerometers, nine devices were validated in the included studies with the BodyMedia SenseWear® (SWA) being the most frequently validated. Although correlations between accelerometers and the gold standard were high in some studies, agreement between the two methods was low, as shown by the Bland–Altman plots. Conclusions Most accelerometer estimations of EE were inaccurate for obese/overweight subjects, and authors advise to improve the accuracy of algorithms for SWA software, or the predicted equations for estimating EE from other accelerometers.

Dietary Factors and Eating Behaviors Affecting Diet-Induced Thermogenesis in Obese Individuals: A Systematic Review.

Obese individuals are considered to have lower energy expenditure (EE) rates than non-obese individuals. We aimed to investigate the effects of various factors related to food intake on diet-induced thermogenesis (DIT) in the EE of obese individuals. Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we reviewed relevant literature from PubMed, Embase, and Medline databases from study inception till the end of July 2019. Studies on dietary factors affecting DIT in obese individuals were included. Fifteen studies were included; these studies assessed macronutrient, single-nutrient, or supplement meal compositions, as well as dietary patterns and behaviors. The effect of obesity on DIT was not constant in each study. Differences in DIT pertained to the protein ratio being higher than the fat ratio or the carbohydrate ratio being higher than the fat ratio. High intake of calcium and vitamin D as well as high-oleic peanut supplements increased DIT in obese people. In addition, ascorbic acid intake, fatty acid saturation, and the chain length of various fatty acids had no effects on DIT. In conclusion, the findings suggest that in obese individuals, DIT is associated with various factors related to meal, nutrient, and dietary habits. However, because of the complexity of the relationship between DIT and obesity, it is difficult to determine the critical element underlying this association.

Effect of Aerobic Exercise Training on Energy Expenditure by Physiological Cost Index in Obese Individuals

Aim: To find the effect of aerobic exercise training on energy expenditure by physiological cost index in obese individuals. Background: Obese individual tend to expend more energy in any particular task as compared to normal weight individuals. Aerobic exercise has been the subject of investigation to improve energy expenditure. Methodology: This was an experimental pre/post study. 30 obese individuals between the age group of 18-28 years were included in the study. All the 30 individuals were divided in a group of 5 each. The difference of pre to post PCI week 1 of each subjects was calculated before the exercise programme. The individuals then underwent a group aerobic exercise training,training was imparted for 3 days for 4 consecutive weeks. The training program included warm up, training phase and cool down. The difference of pre to post PCI week 4 was then calculated. The data was statistically analyzed using student paired t test. Results: Aerobic exercise showed a significant decrease in the physiological coast index after 4 weeks. (p = &lt;0.0001*). Conclusion: A 4 week aerobic exercise training is effective in improving energy expenditure in obese individuals.

High-dose thiamine supplementation may reduce resting energy expenditure in individuals with hyperglycemia: a randomized, double - blind cross-over trial.

Despite the crucial role of thiamine in glucose and energy metabolism pathways, there has been no published study examining the impact of thiamine on energy metabolism in humans. To assess the effects of thiamine supplementation on resting energy expenditure (REE) in individuals with hyperglycemia. Twelve hyperglycemic patients completed this double-blind, randomized trial, where all participants received both thiamine (300mg/day) and matched placebo for 6weeks in a cross-over manner. REE was assessed by indirect calorimetry. Anthropometric measurements, fasting and 2-h plasma glucose, and glucose-induced thermogenesis were also assessed at the beginning and on the completion of each six-week phase. Participants consuming thiamine supplements experienced a significant decrease in the REE assessed at week six compared to the baseline [mean (SE): 1478.93 (73.62) vs.1526.40 (73.46) kcal/d, p = 0.02], and the placebo arm (p = 0.002). These results did not change significantly after adjusting for the participants' body weight and physical activity as potential confounders. Six-week intervention had no significant effect on the participants' body weight or waist circumference, in either supplement or placebo arms (all p values>0.05). However, correlation analysis highlighted significant positive relationships between the changes in REE, and those in fasting (rs = 0.497, p = 0.019) and 2-h plasma glucose (rs = 0.498, p = 0.018) during the six-week intervention period. Supplementation with high-dose thiamine may attenuate REE in patients with impaired glucose regulation. Our findings suggest that the impact of thiamine on REE may in part be explained by improved glycemic control. Australian New Zealand Clinical Trials Registry ACTRN12611000051943. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12611000051943.

Gone fishing: Adélie penguin site-specific foraging tactics and breeding performance

AbstractThe ecological drivers underlying breeding performance are expected to differ across the geographical range of seabird species, but few studies have compared trade-offs between colonies with different local conditions. During chick-rearing (2000–01), we compared the foraging trips, diet and breeding parameters of two Adélie penguin colonies in the Ross Sea, at Edmonson Point (EdPo; ~2000 breeding pairs) and Inexpressible Island (InIs; ~24 000 breeding pairs). Penguins from InIs travelled farther and performed longer feeding trips. The quantity of food brought to the nest was the same for the two colonies, but penguins from InIs brought more fish and less krill. Eggs hatched earlier at EdPo. Breeding success did not differ, but chick weight during hatching–fledging was greater at InIs. Despite worse weather conditions at InIs, the larger proportion of high-energy food brought by penguins from InIs (i.e. fish) may explain their offspring‘s better performance. In addition, the persistence of fast ice at EdPo may have led to greater energy expenditure of breeding individuals, possibly reducing chick growth. The greater intraspecific competition expected at InIs may have been reduced by longer foraging trips and/or counteracted by the more nutritious diet. Our findings reveal complex trade-offs between foraging effort and environmental constraints in determining the breeding performance of Adélie penguins.