Objectives: This study aims to explore the integration of big data and machine learning to enhance energy efficiency in manufacturing, focusing on the opportunities presented by Industry 4.0 and cyber-physical production systems. Theoretical Framework: The research leverages supervised learning techniques to analyze and predict machine-specific energy consumption patterns, utilizing energy disaggregation as a foundational concept. Method: Various machine learning algorithms, including Lasso regression, Linear regression, and Decision Tree, will be employed to develop predictive models for energy usage. Additionally, Explainable Machine Learning (XML) techniques will be utilized to ensure interpretability and clarity in the prediction outcomes. Results and Discussion: The proposed framework aims to elucidate the relationship between equipment utility and energy consumption, providing comprehensible explanations that enhance decision-making processes within intelligent industrial environments. Research Implications: This work highlights the significant potential of XML in transforming machine learning applications in manufacturing, paving the way for improved energy efficiency and operational effectiveness. Originality/Value: The introduction of an innovative framework that combines machine learning with explainability in the context of energy consumption marks a valuable contribution to the fields of manufacturing and sustainable industry practices.