The term uveitis is nonspecific and may be defined as intraocular inflammation. Because there are many uveitis entities, several classification schemes are clinically useful. The four commonly used classifications for describing uveitis entities are temporal, morphologic, anatomic, and causal. The temporal classification of uveitis divides uveitis entities by duration. Acute uveitis is less than 2 weeks in duration. Chronic uveitis is more than 4 to 6 weeks in duration. Recurrent uveitis and intermittent uveitis are also terms used within the temporal classification. The morphologic classification uses pathology terminology to describe a given entity. In this system, uveitis is either nongranulomatous or granulomatous, terms that are usually applied to clinical findings. The terms correlate to the size of keratic precipitates (small in nongranulomatous uveitis and large in granulomatous uveitis), the presence of iris nodules (granulomatous), or the presence of choroidal nodules (granulomatous). The anatomic classification uses the physical examination of the eye and the examiners' assessment of which part of the eye is primarily or solely involved. Hence, this classification scheme uses the terms iritis, iridocyclitis, vitritis, retinitis, retinochoroiditis, choroiditis, and panuveitis, depending on which part of the eye the examiner finds to be involved. The causal classification of uveitis groups entities according to cause. In this system, uveitis may be infectious or noninfectious, endogenous or exogenous, and benign or malignant. The most useful clinical scheme for describing uveitis entities is one that combines each of the four descriptive groupings, using all four of the common modifiers to describe an individual patient. This method of uveitis description is a logical way of helping a clinician who is examining an individual patient narrow the list of diagnostic possibilities and thus determine the most effective management. A specific uveitis diagnosis is the end result of a series of steps common throughout clinical medicine: (1) obtaining the history, (2) examination of the eye, (3) formulation of a differential diagnosis, and (4) obtaining diagnostic studies that may confirm the clinical diagnosis. Only with a specific diagnosis can the course of the condition be predicted for the patient, and specific therapeutic options presented. This article concentrates on infectious uveitis, or uveitis entities caused by identifiable microorganisms. The mechanism may be exogenous or endogenous. For the purpose of clarification, only endogenous infectious entities are discussed here. Infectious uveitis may be bacterial, viral, fungal, or parasitic. Appropriate pharmacologic management of infectious endogenous uveitis may involve anti-inflammatory agents and specific antimicrobial drugs. There are no easy generalizations that may help the clinician decide that a given patient has an infectious uveitis. The history may be quite variable, with duration of symptoms varying widely. The eye examination may yield little help to suggest an infectious cause or may be extremely helpful in pointing to a specific diagnosis. Even though infectious endogenous uveitis is being considered, the fact that all findings may be monocular, does not eliminate an infectious endogenous condition.