You have accessJournal of UrologyKidney Cancer: Surgical Therapy II1 Apr 2015MP57-15 EN BLOC LIGATION OF RENAL VESSELS DURING LAPAROSCOPIC NEPHRECTOMY AND NEPHROURETERECTOMY Mariam Hult, Mikkel Fode, Claus Dahl, and Nessn Azawi Mariam HultMariam Hult More articles by this author , Mikkel FodeMikkel Fode More articles by this author , Claus DahlClaus Dahl More articles by this author , and Nessn AzawiNessn Azawi More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.2003AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Conventionally individual ligation of the renal artery and vein with clips is performed during laparoscopic nephrectomy (LN). Concomitant ligation of the vessels (en bloc ligation) is not standard procedure, due to an expected risk of stapler dysfunction and arteriovenous fistulas (AVF). However, recent studies suggest that en bloc ligation may be a safe procedure offering a reduction in surgical time. The objective of this study was to compare en bloc ligation, using EndoGIA stapler 45/2.5 mm (Covidien Inc, Mansfield, MA), with conventional individual ligation, during LN and laparoscopic nephroureterectomy (LNU), regarding surgical time, blood transfusions and development of AVF. METHODS A retrospective chart review of all patients, undergoing LN or LNU at the Department of Urology, Roskilde Hospital, between January 2010 and April 2014, with a follow-up of minimum 6 months, was performed. Demographic data, indication for surgery, method of ligation, blood transfusions and development of CT-verified AVF were collected. Wilcoxon rank sum test, chi square test and Fisher's exact test were used for univariate analyses. Multivariate analyses were performed with linear and logistic regression. RESULTS 228 patients underwent LN and 56 patients underwent LNU. In the LN group, 77 patients (34%) underwent en bloc ligation. The surgical time was significantly reduced in the en bloc group, with a median of 90 minutes (range 30-180) compared to 110 minutes (range 40-240) in the conventional ligation group (p=0.0001). The difference remained significant after controlling for age, gender, indication for surgery, blood transfusions and robotic surgery (-26 min [95% CI; -17 to -36 min], p<0.0001). Three en bloc patients and one conventional ligation patient received blood transfusions. The difference neither reached statistical significance in the univariate analysis (p=0.11) nor after controlling for age, gender, indication for surgery and robotic surgery (p=0.068). In the LNU group, 7 patients (13%) underwent en bloc ligation. There was no significant difference between conventional ligation and en bloc ligation in surgical time on either univariate (p=0.8) or multivariate (p=0.07) analyses. None of the patients needed blood transfusions. With a mean follow-up of 13 months (range 6-50), no AVF were found in any of the 284 patients. CONCLUSIONS En bloc ligation appears to be safe and can reduce the surgical time during LN without increased risk of blood transfusions, or development of AVF. Further studies are needed to assess possible advantages using the method during LNU. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e695 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mariam Hult More articles by this author Mikkel Fode More articles by this author Claus Dahl More articles by this author Nessn Azawi More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...