End Of Fiber Research Articles

Fiber-optic temperature sensor based on glass Fabry–Perot interferometer

The paper presents a theoretical and experimental study of a fiber-optic all-glass microthermometer based on a Fabry–Perot interferometer. The interferometer is fabricated by applying borosilicate glass to the cleaved end of a standard telecom single-mode optical fiber using a microforge. According to the results of experimental studies, the spectral sensitivity of the fabricated interferometer was about 40 pm/°C. A mathematical model of the Fabry–Perot interferometer based on the method of scattering and transfer matrices is presented and verified, which makes it possible to calculate the spectral response of an interferometer with arbitrary structure parameters.

Polymer Microtip-Based Fabry-Perot Interferometer for Water Content Determination in the Gas and Liquid Phase.

In this work, we present a Fabry-Perot interferometer (FPI) based on a polymer microtip for water content determination in both the gas and liquid phase. The polymer tip of pentaerythritol triacrylate (PETA) is fabricated at the end of an optical fiber by self-guiding photopolymerization, forming at the same time a low-fineness Fabry-Perot interferometer and a sensing layer for water thanks to hydroxyl groups present in PETA. The PETA tip shows a clear interferometric signal, which is highly sensitive to the change of the water content in the environment. The FPI signal shifts with a constant sensitivity of 90 pm/%RH, which corresponds to a relative sensitivity of 104 ppm/% RH, in the range of relative humidity from 30 to 80%. In liquid, the FPI sensor shows a nonlinear sensitivity, up to 158 pm/wt % as the water content is below 40 wt % in water/glycerol mixtures. The cross effect of the temperature on the PETA tip is demonstrated to be negligible as the FPI signal is insensitive to temperature changes from 23 to 70 °C. More importantly, the interaction between the tip and the environment affecting the FPI signal is demonstrated experimentally. The proposed FPI sensor is therefore promising for the direct, sensitive, and reliable determination of the water content of products.

Microscopic failure characteristics and critical length of short glass fiber reinforced composites

Short glass fiber reinforced composites (SGFRC) are frequently used to manufacture parts with complex surfaces by injection or compression molding. It was found that the length of fibers is often reduced during the manufacturing processes. To understand the causes of the change in fiber length, ex-situ 3D CT images are taken from tensile experiments to extract the information of the microstructure of the SGFRC, including fiber length, orientation and breakage. In the calculation of the critical length, the Kelly model is modified to include the effect of the stresses at fiber ends and the mechanical effect of internal pore defects on the composites. It is found that the microscopic interaction of short fibers breaks longer fibers, until they are shorter than the critical length. Through comparisons, it is found that the modified Kelly model is more accurate in predicting critical length of short fibers. In this study, micro-failure modes, such as fiber pulling out, interface debonding, matrix damage and pore destruction, are all characterized by micro-CT and scanning electronic microscope to analyze the complex failure mechanisms. The micro failure modes are mainly attributed to the micro geometric features and mass fraction of short fibers.

Threshold design in fiber termination identification using local injection and OTDR

We study how to set a threshold for how to identify the end of an optical fiber by reflectance ratio between wavelengths calculated from measurements of a temporary optical coupler (TOC) and a two-wavelength Optical Time Domain Reflectometer (OTDR). The threshold is affected by the difference in propagation loss between the wavelengths from the OTDR to the end of the optical fiber. The effectiveness of the threshold is inferred from measurements of the reflectance ratio of an Optical Network Unit (ONU) used for a Passive Optical Network (PON) and the propagation loss difference between the wavelengths of the TOC. The threshold adaptation conditions are also explained. Our results show that even with the worst propagation loss of existing single-mode fiber standards, it is possible to identify fiber ends 3.8 km away. However, if large bending or connection losses occur between the OTDR and the fiber end, the propagation loss difference between the wavelengths of the TOC must be improved.

Scanning darkfield high-resolution microendoscope for label-free microvascular imaging.

Characterization of microvascular changes during neoplastic progression has the potential to assist in discriminating precancer and early cancer from benign lesions. Here, we introduce a novel high-resolution microendoscope that leverages scanning darkfield reflectance imaging to characterize angiogenesis without exogenous contrast agents. Scanning darkfield imaging is achieved by coupling programmable illumination with a complementary metal-oxide semiconductor (CMOS) camera rolling shutter, eliminating the need for complex optomechanical components and making the system portable, low-cost (<$5,500) and simple to use. Imaging depth is extended by placing a gradient-index (GRIN) lens at the distal end of the imaging fiber to resolve subepithelial microvasculature. We validated the capability of the scanning darkfield microendoscope to visualize microvasculature at different anatomic sites in vivo by imaging the oral cavity of healthy volunteers. Images of cervical specimens resected for suspected neoplasia reveal distinct microvascular patterns in columnar and squamous epithelium with different grades of precancer, indicating the potential of scanning darkfield microendoscopy to aid in efforts to prevent cervical cancer through early diagnosis.

Differences between migrasome, a 'new organelle', and exosome.

The migrasome is a new organelle discovered by Professor Yu Li in 2015. When cells migrate, the membranous organelles that appear at the end of the retraction fibres are migrasomes. With the migration of cells, the retraction fibres which connect migrasomes and cells finally break. The migrasomes detach from the cell and are released into the extracellular space or directly absorbed by the recipient cell. The cytoplasmic contents are first transported to the migrasome and then released from the cell through the migrasome. This release mechanism, which depends on cell migration, is named 'migracytosis'. The main components of the migrasome are extracellular vesicles after they leave the cell, which are easy to remind people of the current hot topic of exosomes. Exosomes are extracellular vesicles wrapped by the lipid bimolecular layer. With extensive research, exosomes have solved many disease problems. This review summarizes the differences between migrasomes and exosomes in size, composition, property and function, extraction method and regulation mechanism for generation and release. At the same time, it also prospects for the current hotspot of migrasomes, hoping to provide literature support for further research on the generation and release mechanism of migrasomes and their clinical application in the future.

Ultracompact Optical Fiber Sensor for Inner Diameter Measurement

ABSTRACT An ultracompact optical fiber Fabry–Perot interferometric sensor is proposed and demonstrated for inner diameter measurement of a capillary tube. The device is a section of single-mode fiber with an angle-polished end face of 45°. When the device is placed inside the capillary tube and in close contact with its inner wall surface, the reflected light from the angle-polished fiber end face is directed sequentially to the fiber core–cladding, cladding–air, and air–capillary interfaces, respectively, and reflected back, and finally returned to the fiber core after being reflected by the angle-polished fiber end face again. As a result, a cascaded Fabry–Perot interferometer system is constructed, which is well suitable for the inner diameter measurement of the capillary tube. Moreover, the wall thickness of the transparent capillary tube can also be conveniently measured by using the same device in slightly different configuration. The relative error of the measurement is small compared with the data provided by the manufacturer. Such a device is ultracompact, robust, flexible, and convenient in operation and is especially attractive for implementing the measurement in a tight or hard-to-reach spatial environment.

Optimization of WLS fiber readout for the HERD calorimeter

A novel 3-D calorimeter, composed of about 7500 LYSO cubes, is the key and crucial detector of the High Energy cosmic-Radiation Detection (HERD) facility to be installed onboard the China Space Station. Energy deposition from cosmic ray in each LYSO cube is translated by multiple wavelength shifting (WLS) fibers for multi-range data acquisition and real-time triggering.In this study, various methods of surface finish and encapsulation of the LYSO cube were investigated to optimize the amplitude from the WLS fiber end with the aim of improving the signal-to-noise ratio of Intensified scientific CMOS (IsCMOS) collection. The LYSO cube with five rough surfaces and a specular reflector achieves the maximum amplitude at the low-range fiber end, which is increased by roughly 44% compared to the polished cube with PTFE wrapping.The non-uniformity of amplitude at different positions on the LYSO cube surface was measured by X-ray and the positional correlation factor was derived for the entire cube. A simulation based on HERD CALO was conducted, which revealed that both the LYSO cube with five rough surfaces and the cube with rough bottom face exhibit superior energy resolution for electrons compared to the other two configurations.

A Mid-Infrared Multifunctional Optical Device Based on Fiber Integrated Metasurfaces.

A metasurface is a two-dimensional structure with a subwavelength thickness that can be used to control electromagnetic waves. The integration of optical fibers and metasurfaces has received much attention in recent years. This integrated device has high flexibility and versatility. We propose an optical device based on fiber-integrated metasurfaces in the mid-infrared, which uses a hollow core anti-resonant fiber (HC-ARF) to confine light transmission in an air core. The integrated bilayer metasurfaces at the fiber end face can achieve transmissive modulation of the optical field emitted from the HC-ARF, and the Fano resonance excited by the metasurface can also be used to achieve refractive index (RI) sensing with high sensitivity and high figure of merit (FOM) in the mid-infrared band. In addition, we introduce a polydimethylsiloxane (PDMS) layer between the two metasurfaces; thus, we can achieve tunable function through temperature. This provides an integrated fiber multifunctional optical device in the mid-infrared band, which is expected to play an important role in the fields of high-power mid-infrared lasers, mid-infrared laser biomedicine, and gas trace detection.

Comparison of brain functional response to mechanical prickling stimuli to the glabrous and hairy skin.

A kind of prickle sensation, which is a composite feeling of pain and itch, can be evoked by mechanical stimulation of fiber ends from fabric surface against to human hairy skin, rather than glabrous skin. Now, a functional magnetic resonance imaging (fMRI) study was conducted to investigate the cognitive differences in the brain for mechanical prickling stimuli to the two types of skin. A nylon filament with the diameter of 205μm and the length of 8mm was used to deliver mechanical prickling stimuli respectively to two skin sites, fingertip (glabrous skin) and volar forearm (hairy skin), of eight healthy male subjects. Simultaneously, the technology of fMRI was adopted to acquire BOLD (Blood Oxygen Level-Dependent) signals of brain functional response of the subjects. Somatosensory areas, emotional areas, and the posterior parietal cortex (especially the precuneus) are important brain regions that distinguish between the two conditions. The representation of mechanical prickling stimulation to glabrous skin in the brain favors much more the tactile information of the stimulation and contains no itch, while the key brain area, precuneus, involved in itch was activated by the same mechanical prickling stimulation to hairy skin, and brain response for the condition of hairy skin contains more emotional information, which plays an important role in pain processing. Therefore, it can be inferred that a kind of stronger prickle sensation, which contains both pain and itch, was evoked by mechanical stimulation to hairy skin than glabrous skin.

Toward single-cell epigenome analysis: A microfluidic device for isolating, stretching, and imaging individual chromosomes

We developed a microfluidic device with microstructures that can moor the ends of chromatin fibers obtained by unfolding single intact chromosomes. This mooring involves trapping both ends of the chromosome with antibody-conjugated microspheres and placing each microsphere on the microstructure. In principle, the device is structured in such a way that mooring of chromatin fibers, i.e., partially unfolded chromosomes, is achieved under uniform tension, which is necessary to obtain an accurate distribution of folded/unfolded regions and fluorescence probes on the chromatin fibers. In addition, changes in the distribution of chromatin folding structures were observed by controlling the solution conditions, and specific histone chemical modification regions were visualized by immunofluorescence staining of chromatin fibers in the elongated form with uniform tension. This method is advantageous for the epigenetic analysis of non-fragmented natural chromatin fibers.

The Effect of Fiber End on the Bonding Mechanical Properties between SMA Fibers and ECC Matrix

In order to investigate the effect of fiber end on the bonding mechanical properties between shape memory alloy (SMA) fibers and Engineered Cementitious Composites (ECC), this study designed and fabricated five groups of specimens with variations in SMA fiber end shape, diameter and depth-to-diameter ratio. Direct tensile tests were conducted on these specimens under displacement control. The failure modes, stress–strain curves and various performance indicators were analyzed to evaluate the bonding mechanical properties and the effects of different factors. The results revealed that for straight-end SMA fibers, increasing the diameter and depth-to-diameter ratio both led to a decrease in bonding strength. On the other hand, the N-shaped end provided sufficient anchorage force for SMA fibers, resulting in a maximum pull-out stress of 926.3 MPa and a fiber strength utilization of over 78%. Increasing the fiber diameter enhanced the maximum pull-out stress and maximum anchorage stress for N-shaped-end SMA fibers but reduced the fiber strength utilization. These research findings provide a solid theoretical basis and data support for achieving a synergistic effect between SMA fibers and the ECC matrix.

Simultaneous sensing of strain and temperature based on the inline-MZI embedded point-shaped taper structure with low crosstalk.

An embedded spherical dot taper structure (EDT) based on the MZI principle is proposed in this paper, which is mainly fabricated by using two special arc discharges in the preparation process. The proposed structure involves two specialized arc discharge techniques. First, an oversaturated discharge fusion process creates a micro-arc spherical area on the fiber end face to form the first link type. Second, an unsaturated discharge-pulling taper fusion joint creates a local micro-extrusion operation on this micro-arc fiber end face to form the second link. The thermal stress from instantaneous discharge causes a reverse spherical expansion zone to form in the end face structure, similar to the micromachining of long-period fiber gratings that use local CO2 laser etching to create modulated zones. The study involves a mathematical and theoretical analysis of how geometric parameters in the spherical modulation zone impact the structure's characteristic spectrum. The research demonstrates the potential for this structure to function as a light-intensity modulated strain sensor device through both theoretical and experimental means. As per the experimental findings, the optimized structure displays a high level of strain sensing sensitivity at 0.03 dB/µε and temperature sensing sensitivity of 73 pm/°C (20°C-75°C) and 169 pm/°C (75°C-120°C). Additionally, it possesses excellent cross-sensitivity at only ∼0.0015 µε/°C. Therefore, this sensor presents a favorable option for strain and temperature synchronization sensing and monitoring components, and exhibits notable application prospects in precision engineering, which encompasses mechanical manufacturing, the power and electrical industry, healthcare domain, and certain specialized areas of small-scale precision engineering.

Numerical analysis of graphene oxide modified glass fiber/epoxy resin composites

Graphene is extensively used as a functional material due to its superb heat transfer and electrical conductivity properties. In this paper, sample graphene oxide /glass fiber/epoxy resin composites were prepared by ultrasonic decentralization. The heat transfer and stress distribution of the graphene-doped fiber-reinforced resin matrix composites were simulated by mathematical modelling. The reliability of the numerical heat transfer model is illustrated by comparing the measured temperature field distribution of the graphene oxide/glass fiber/epoxy composite samples with the numerical simulation results. It is also shown that graphene particles can facilitate heat transfer and the epoxy resin in the composite expands significantly more than the fibers, so the compressive stress on the fibers at the interface strengthens the bond between resin and fibers. Still, the thermal stress can cause the glass fiber ends to detach from the resin material and affect the material life.

Raman Spectroscopy Fiber Probe Based on Metalens and Multimode Fiber for Malachite Green Determination

The limit of Raman spectroscopy probe based on the traditional objective lens, such as integration difficulties, is the primary motivation to find better alternatives. Due to the potential of vertical integration and significant flexible design, a Raman spectroscopy fiber probe based on metalens at the fiber end facet is demonstrated. Using the "contact and separate" method, we successfully transferred the metalens to the end face of multimode fiber (MMF) to construct the Raman fiber probe with an ultrahigh numerical aperture (NA) of up to 0.66@air. In the case of the surface-enhanced Raman scattering (SERS) substrate composed of Au-plated anodic aluminum oxide (AAO) membrane with the same dry malachite green (MG), compared with the commercial Raman scattering light acquisition system based on an objective lens, our Raman signal intensity increases by at least 2.7 times at the Raman characteristic peak for MG. In the MG aqueous solution, the measurement with a limit of detection (LOD) of 10-9 mol/L@1616 cm-1 is realized. The proposed SERS sensing configuration based on the proposed Raman fiber probe and Au-covered AAO membrane also shows a broad application potential of real-time monitoring for other markers in the fields of food safety and environment detection.

Glucose Sensor Using Sol-Gel Coating Layer Deposited on PMMA Optical Fiber: An Enzyme Activity Measurement System.

In the present work, a biocatalytic glucose optical sensor produced by immobilizing glucose oxidase (GOD) as a recognition molecule over a PMMA (polymethylmethacrylate) optical fiber is introduced. An enzymatic encapsulation process was carried out using the sol-gel method, depositing a TEOS-based coating by immersion at the end of an optical fiber; the biosensor was characterized using different glucose levels. Finally, the best way to encapsulate the enzyme and prevent it from degrading is to perform the process at room temperature, and later implement the deposition of the coating on the fiber. The drying process was optimal below 8 °C.

Efficient fluorescence coupling microlens integrated fiber magnetometer probe based on nitrogen vacancy centers.

The nitrogen vacancy (NV) centers in diamonds have gathered increasing interest as an emerging quantum sensing platform with high sensitivity and spatial resolution. Integration of micro-sized diamond and fiber is an essential method to build an NV center endoscope probe and enable NV center sensors for practical application. However, the low fluorescence collection efficiency of fibers due to their small numerical aperture (NA) has limited the sensitivity of the sensors. In this paper, a cone-shape microlens was fabricated using the photopolymerization process at the end of a multimode fiber to boost the laser excitation and fluorescence collection efficiency of NV centers. Experiments demonstrated that over 21 times fluorescence intensity enhancement and 12 times sensitivity improvement were achieved. This fiber-microlens magnetometer probe exhibited a 2.1-nT/Hz1/2 sensitivity over a bandwidth of 100 Hz with ∼80-µm diameter diamond. This research presented a robust and large NA diamond integrated fiber-microlens magnetometer probe, which can also be expanded to magnetic field scan and real-time monitoring.

The Rising of Fiber Constructed Piezo/Triboelectric Nanogenerators: From Material Selections, Fabrication Techniques to Emerging Applications

AbstractPiezo/triboelectric nanogenerators (PTNGs) have become the research frontier in many cutting‐edge applications, which open up promising possibilities for broad prospects. Fiber materials are the ideal candidate for constructing high‐performance PTNGs owing to the compelling features of lightweight, programmable structure, favorable softness, and brilliant breathability. To this end, working mechanisms, material selections, structural designs and fabrication methods of fiber constructed PTNGs are comprehensively presented. An in‐depth analysis of emerging applications ranging from intelligent clothing, smart home, and personalized medicine to artificial intelligence is thoughtfully demonstrated. Furthermore, the current problems and potential challenges that hinder their large‐scale commercial applications are systematically discussed, laying emphasis on the future development direction of fiber constructed PTNGs. It is expected that this review will supply the audience with some universal strategies and fresh ideas to conduct deep research on fiber constructed PTNGs toward better performance.

Effects and mechanisms of substance P on the proliferation and angiogenic differentiation of bone marrow mesenchymal stem cells: Bioinformatics and in vitro experiments

The slight release of substance P (SP) from the end of peripheral nerve fibers causes a neurogenic inflammatory reaction, promotes vascular dilation and increases vascular permeability. However, whether SP can promote the angiogenesis of bone marrow mesenchymal stem cells (BMSCs) under high glucose conditions has not been reported. This study analyzed the targets, biological processes and molecular mechanisms underlying the effects of SP on BMSCs. BMSCs cultured in vitro were divided into a normal control group, high glucose control group, high glucose SP group and high glucose Akt inhibitor group to verify the effects of SP on BMSCs proliferation, migration and angiogenic differentiation. SP was found to act on 28 targets of BMSCs and participate in angiogenesis. Thirty-six core proteins, including AKT1, APP, BRCA1, CREBBP and EGFR, were identified. In a high glucose environment, SP increased the BMSCs proliferation optical density value and cell migration number and reduced the BMSCs apoptosis rate. In addition, SP induced BMSCs to highly express the CD31 protein, maintain the wall structure integrity of the matrix glue mesh and promote increases in the number of matrix glue meshes. These experiments showed that in a high glucose environment, SP acts on 28 targets of BMSCs that encode core proteins, such as AKT1, APP and BRCA1, and improves BMSCs proliferation, migration and angiogenic differentiation through the Akt signaling pathway.

Computational model of integrin adhesion elongation under an actin fiber.

Cells create physical connections with the extracellular environment through adhesions. Nascent adhesions form at the leading edge of migrating cells and either undergo cycles of disassembly and reassembly, or elongate and stabilize at the end of actin fibers. How adhesions assemble has been addressed in several studies, but the exact role of actin fibers in the elongation and stabilization of nascent adhesions remains largely elusive. To address this question, here we extended our computational model of adhesion assembly by incorporating an actin fiber that locally promotes integrin activation. The model revealed that an actin fiber promotes adhesion stabilization and elongation. Actomyosin contractility from the fiber also promotes adhesion stabilization and elongation, by strengthening integrin-ligand interactions, but only up to a force threshold. Above this force threshold, most integrin-ligand bonds fail, and the adhesion disassembles. In the absence of contraction, actin fibers still support adhesions stabilization. Collectively, our results provide a picture in which myosin activity is dispensable for adhesion stabilization and elongation under an actin fiber, offering a framework for interpreting several previous experimental observations.