Enamel In Children Research Articles

Prevalence of hypomineralized second primary molars and association with socioeconomic characteristics and dental caries in a Brazilian population of preschoolers: a cross-sectional study.

To analyze the prevalence of hypomineralized second primary molar (HSPM) and its association with socioeconomic characteristics and dental caries in a Brazilian population of preschoolers. 603 preschoolers, enrolled in public preschools in Itajaí (state of Santa Catarina, Brazil), took part in the study. To assess the participants' socio-economic characteristics, an original questionnaire was formulated and sent to the children's parents. The clinical evaluation was carried out by a calibrated examiner using the deft/DMFT index for dental caries and Ghanim et al. (Ghanim et al., Eur Arch Paediatr Dent, 2015) criteria for HSPM. The data were analyzed through Poisson regression, using STATA statistical software, and the association analyses were presented by prevalence ratios (PR). The prevalence of at least one HSPM-affected second molar was 24.5%. The prevalence of HSPM was associated to the city's geographical regions of the Educational hubs (p < 0.001). A significant association was found between dental caries and HSPM (p = 0.003; PR: 1.31; 95% CI 1.09-1.56). Children with HSPM were 31% more likely to experience dental caries than children without HSPM. Geographical regions of educational hubs were also significantly associated with HSPM (p < 0.001). None of the socioeconomic characteristics was associated with HSPM (p > 0.05). HSPM is a common developmental defect of enamel in children in our study. The HSPM distribution was associated with the city's geographic regions. Children with HSPM are more likely to experience dental caries. Socioeconomic characteristics were not associated with HSPM.

Prenatal exposure to environmental toxins and comprehensive dental findings in a population cohort of children.

Environmental toxins are known to have many impacts on growth and development in humans, starting in utero. Alterations in amelogenesis, caused by chemical and physical trauma that occur during the antenatal, perinatal and postnatal time periods, may result in developmental defects in deciduous and permanent tooth enamel, as demonstrated in animal studies. These defects can be clinically visible and result in a variety of morphological and functional problems in the dentition. Since enamel does not remodel after formation, it may serve as a permanent record of insults during organ development.Our primary purpose was to investigate any possible relationship between intrauterine exposure to endocrine disrupting chemicals (phenols and phthalates) and developmental defects in enamel in children, while also accounting for fluoride exposure. Our secondary purpose was to report descriptively on findings from comprehensive dental examinations performed on 356 children that were drawn from the general paediatric population. A cohort of children from the Utah Children's Project (N = 356) that had full medical exams, comprehensive medical and family histories and available biospecimens were given extraoral and intraoral examinations. They also completed an oral health questionnaire. Standardized intraoral photographs were taken of the teeth and viewed by standardised examiners and the dental observations were recorded for a full inventory of findings, including: tooth morphology, caries, restorations, colorations, attrition, erosion, fractures and hypomineralization. Perinatal maternal urine samples were assessed for the concentration of fluoride, phenols and phthalates, including bisphenol A (BPA).Pairwise statistical analyses were done to correlate the dental findings with one another and with the presence of environment chemicals found in the urine samples. Hypomineralization was the most common finding (96% of children; 37% of deciduous teeth, 42% of permanent teeth), consistent with molar incisor hypomineralization (MIH) described in other human populations. No consistent correlations were seen between dental findings and the presence of phenols and phthalates in prenatal urine, but the number of samples available for the assessment was limited (n = 35).In conclusion, we found a high proportion of dental hypomineralization in a population based paediatric cohort, but did not find an association with prenatal exposure to phenols and phthalates.

Stunting dan Malnutrisi Penyebab Kelainan Email Gigi Anak dan Early Childhood Caries (ECC): Komprehensif Review

Background: Childhood dental health is a vital component of overall well-being, with Early Childhood Caries (ECC) and defect enamel being major concerns. This article explores the intricate connection between stunting, malnutrition, and the development of defect enamel and ECC in children. Methods: Narrative review use Pubmed and Google Scholar databases with article inclusion criteria, namely research articles and reviews that discuss the relationship between enamel defects and malnutrition and ECC with malnutrition Results: Childhood malnutrition, characterized by inadequate intake of essential nutrients, poses a significant global health challenge. Stunting, a manifestation of chronic malnutrition, adversely affects physical growth and cognitive development in children. However, the link between malnutrition and dental health has not received adequate attention. This article examines the mechanisms through which malnutrition, specifically stunting, can contribute to the development of defective enamel in children. Nutritional deficiencies, particularly in calcium, vitamin D, and fluoride, are identified as key culprits in compromising enamel formation and strength. Weakening of the enamel leaves teeth vulnerable to dental caries, including ECC, which can lead to pain and long-term oral health problems. The complex relationship between malnutrition, stunting, defect enamel, and ECC calls for multifaceted solutions. Conclusion: This article highlights the importance of holistic public health initiatives, which encompass nutritional education for caregivers and improved access to dental care services for at-risk children. Interdisciplinary collaboration among healthcare professionals is emphasized to address the synergistic nature of these interconnected health challenges.

Could sleep quality in pregnant women be related to developmental defects of enamel in children?

Anatomical, physiological and hormonal changes occur in women during pregnancy. These phenomena can affect sleep quality, exerting a negative impact on health. Studies suggest that sleep disorders in this period can also affect the health of the fetus. Sleep disorders may interfere with the expression of genes associated with amelogenesis in the fetus. Clock genes are the basis of internal time keeping (circadian rhythm) and are involved in the formation of mineralized dental tissues. Fetal tooth formation is a complex physiological process that begins during intrauterine life, extending to around eight years of age, and can be affected by numerous internal, external, natal and postnatal events. Abnormalities in any stage of development of the dental enamel may have repercussions in the form of permanent defects and marks clinically represented by the presence of grooves, depressions and diffuse or demarcated opacities, which can compromise function and esthetics. Thus, changes in the awake/sleep pattern can affect the tooth formation process. The hypothesis proposed in this paper is that changes in sleep and the circadian rhythm can affect the molecular bases involved in enamel formation either during the intrauterine period or in the first years of life, causing enamel anomalies. This is because the maternal circadian rhythm has a relationship with the circadian clock of their offspring, demonstrating numerous consequences of the imbalance in this relationship on the child's systemic and oral health. New perspectives with regards to oral outcomes may arise from this discussion, such as a greater importance placed on sleep quality in pregnant women and infants.

RANTES and developmental defects of enamel in children: A Brazilian prenatal cohort (BRISA).

Little is known about the effect of maternal immunological factors on the etiology of developmental defects of enamel (DDE). RANTES (Regulated on Activation Normal T Cell Expressed and Secreted) is a chemokine produced by fibroblasts, lymphoid and epithelial mucosa cells in response to various external stimuli. Despite its importance for embryogenesis, RANTES expression has been demonstrated in multiple diseases characterized by inflammation, tumor and immune response, and wound healing. We hypothesized that altered levels of RANTES during pregnancy are associated with the immune and inflammatory response in women, which could lead to the occurrence of DDE in utero (DDE-iu), directly or mediated by preterm birth. Therefore, this study aimed to evaluate the direct and indirect effects of serum levels of RANTES in pregnant women in the occurrence of DDE-iu in children. This is a longitudinal case-control study. The mothers and their children (327) were evaluated in three moments: prenatal care, post childbirth, and when the child was between 12.3 and 36 months of age. The analysis was performed with structural equation modeling, estimating the standardized coefficient (SC), adopting α = 5%. There was a direct and negative effect of RANTES on the outcome (SC = -0.137; p = 0.022). This association was not mediated by preterm birth (SC = 0.007; P = 0.551). When considering the specific types of DDE-iu, RANTES had a direct effect on hypoplasia (SC = -0.190; p = 0.007), but not on opacity (SC = 0.343; p = 0.074). Lower serum levels of RANTES may contribute to a higher number of teeth with DDE-iu, specifically hypoplasia. However, more evidence supported by clinical, laboratory and epidemiological studies is still needed.

Assessment of the developmental defects of the enamel in children and adolescents with sickle cell disease: a comparative study.

Sickle cell disease (SCD) is the most important hemoglobinopathy in terms of frequency and social impact and can affect the stomatognathic system. To assess and compare the developmental defects of the enamel (DDE) in children and adolescents with and without SCD DESIGN: This was a cross-sectional, analytical, and comparative study of 210 children and adolescents aged 5-18 years, who visited the Hematology and Hemotherapy Hospital of Pernambuco. DDE was observed in 55.2% of the SCD patients and 35.2% of the non-SCD patients (healthy group) (p < 0.05). In the SCD group, DDE was more common in females than in males (69.1% vs. 40.0%; p < 0.05). The incidence of DDE in the permanent teeth was higher in the upper arch than in the lower arch (SCD group, 13.1% vs. 4.6%; healthy group, 8.9% vs. 3.6%; p < 0.05). Compared to the healthy group, the SCD patients were almost twice as likely to develop DDE, mostly affecting females and the permanent teeth. These findings suggest that individuals with SCD need early dental care to avoid future oral problems.

Effectiveness and Color Stability of Resin Infiltration on Demineralized and Hypomineralized (MIH) Enamel in Children: Six-month Results of a Prospective Trial.

To evaluate the masking effect and color stability of resin infiltration treatment in demineralized (white spot lesion) and hypomineralized (molar incisor hypomineralization) enamel lesions of young permanent anterior teeth. Eighty-four (84) anterior teeth with molar incisor hypomineralization or white spot lesions were treated with resin infiltration. The CIE L*a*b* values of sound enamel and enamel lesions were assessed with spectrophotometer and digital image analysis at baseline, immediate postop, 1 week and 6 months. The difference in ΔL, Δa, Δb, and ΔE measurements between sound enamel and the enamel lesions was compared using the repeated analysis of variance (ANOVA) test at p < 0.05. The enamel lesions were clearly discernible from the sound adjacent enamel at baseline. After resin infiltration, there was a significant drop in ΔE values of sound enamel and enamel lesions compared to baseline, and this difference did not change for 6 months, indicating a durable masking effect. At baseline and after 6 months, there was no significant difference in the ΔE values of the test groups. The demineralized and hypomineralized enamel defects were effectively masked by resin infiltration, which remained clinically stable for 6 months.

Інтенсивність карієсу та структурно-функціональна кислотостійкість емалі зубів у дітей з ортодонтичною патологією

The purpose of the study was to analyze the indices of caries intensity and the structural-functional acid resistance of tooth enamel in children with orthodontic pathology during its treatment with fixed equipment. Materials and methods. 53 children aged 14 to 17 years old with orthodontic pathology were examined. The state of oral hygiene was assessed by the OHI-S index, the intensity of carious lesions of the teeth – by the index of carious, filled and removed teeth, and the structural-functional acid resistance of tooth enamel – according to the enamel resistance test with an assessment by a computer program. The children were given measures for sanitation and professional oral hygiene. Orthodontic pathology was treated using the vestibular bracket systems. A year later, the indices and the increase in the intensity of caries were determined again. Results and discussion. The average index of the structural-functional acid resistance of tooth enamel was 4.40 ± 0.26 points, while 15 children (28.3%) had a high level (the enamel resistance test index 1.92 ± 0.24 points), in 26 children (49.1%) the level was average (the enamel resistance test value 4.35 ± 0.10 points), 9 children (17.0%) and 3 children (5.7%) had low (6.36 ± 0.15 points) and very low (8.33 ± 0.33 points) levels. The index of carious, filled and removed teeth in all children was 3.87 ± 0.29. In children with a high level of the structural-functional acid resistance of enamel, the initial index of carious, filled and removed teeth was significantly (p&lt;0.05) the lowest and amounted to 2.23 ± 0.47, in children with an average level – 4.04 ± 0.39, with a low level – 4.7 ± 0.54, with very low – 6.33 ± 1.45. A year later, the overall rate of caries intensity significantly (p&lt;0.05) increased to 5.55 ± 0.43. In children with a high level of the structural-functional acid resistance of enamel, the index of carious, filled and removed teeth was again significantly (p&lt;0.05) the lowest and amounted to 2.93 ± 0.43, with an average level of structural-functional acid resistance it was 5.15 ± 0.38, with a low and very low level – 9.22 ± 0.52 and 11.00 ± 1.53. The indices of the increase in the intensity of the carious lesion was respectively 0.47; 1.12; 4.33 and 4.67. Only 4 children (7.5%) had a high level of the structural-functional acid resistance, that is, the number of children with such level decreased by 3.8 times, 23 children (43.4%) had an average level of the structural-functional acid resistance, at the same time low and very low level of structural-functional acid resistance was established in 20 (37.7%) and 6 children (11.3%), which, respectively, is by 2.2 and 2 times higher than the primary values. According to the repeated enamel resistance test in children with a high level of the structural-functional acid resistance, this index was 1.75 ± 0.48 points, with an average level – 4.17 ± 0.08 points, with low and very low – 6.35 ± 0.11 and 8.50 ± 0.22 points. Conclusion. The results of the study indicate a high risk of developing dental caries in children under the conditions of treatment of orthodontic pathology with fixed equipment and the need to search for caries prevention measures depending on the level of the structural-functional acid resistance of tooth enamel

Developmental defects of enamel in children born preterm.

IntroductionTo investigate manifestations of developmental defects of enamel (DDE) in children born preterm (PT), and to explore possible neonatal morbidities related to DDE manifestation and severity.MethodsA cohort study of 52 children born before gestational week 32 and treated in the neonatal intensive care unit; and 55 children born at full term (FT) as a control group. All the children had a dental examination at age 1–4 years by a professional pediatric dentist. DDE was defined as an alteration in the enamel surface.ResultsDDE were observed in 23 (44%) and 6 (11%) children, in the PT and FT groups, respectively, odds ratio (OR) = 6.47. The OR for damaged anterior teeth was 12.87 times higher in the PT group. DDE of molars was diagnosed in 19% and 11% of the respective groups. In the PT group, the OR of DDE was 4.1 higher among those with than without respiratory distress. The risk for DDE was 5.7 higher in those who received surfactant than in those who did not. Ventilation length, both invasive and non-invasive, was significantly related to DEE.ConclusionsDDE was higher in children born PT than FT. The DDE rate was lower than expected based on current literature, and considering the overall increase in survival; this suggests improvement in treatments affecting DEE. Respiratory distress syndrome, surfactant administration reflecting the need for intubation, longer ventilation and local oral trauma were risk factors for DDE. We recommend routine dental examinations in follow up of children born PT, particularly those exposed to assisted ventilation.

ENAMEL ACIDITY RESISTANCE IN CHILDREN 7-12 YEARS OLD WITH CARIES OF TEMPORARY AND PERMANENT TEETH AND WITH INACTIVE TEETH

Caries remains an important dental problem in childhood. The resistance of teeth to caries is due to the resistance of the enamel, the formation of which depends on a signifi cant number of general and local factors.The aim of the research. Study of acid resistance of enamel in children of diff erent ages and with diff erent dental status.Material and methods. We surveyed 134 children aged 7-9 years and 89 children aged 10-12 years who study in schools in Poltava. Dental examination was performed according to the generally accepted method. In all children, the intensity of caries. To determine the resistance of tooth enamel to caries used the test of enamel resistance according to Okushko VR, Kosareva LI.Results. The average enamel resistance test in children 7-9 years is 4.07±0.11 points. During the division of children into groups with and without caries, signifi cant diff erences were found (4.67±0.10 points and 2.59±0.09 points, respectively).In children aged 10-12 years, the average enamel resistance test is 4.29 ± 0.12 points, which corresponds to moderate enamel resistance. In children with caries of temporary and permanent teeth, it is also moderate (4.67±0.09 points), but the numerical values are slightly worse than average. In children 10-11 years with caries of temporary teeth, the enamel resistance test index is almost no diff erent from that of children with intact temporary teeth. We found that the rate of caries of temporary and permanent teeth has a direct correlation with the test of enamel resistance (R=0.76; p&lt;0.001).Conclusions. The course of caries in children 7-12 years is due to reduced resistance of teeth to caries, as evidenced by the results of the study of acid resistance of enamel on the test of enamel resistance.

Developmental defects of enamel and dental anomalies in five-year-old cleft patients

INTRODUCTION Children born with cleft lip and/or palate (CLP) have a higher prevalence of developmental defects of enamel and dental anomalies, and are at an increased risk of developing dental caries. The aim of this study was to establish the prevalence of dental anomalies and developmental defects of enamel in children born with CLP, and to assess compliance with dental prevention. METHODS Data were collected retrospectively for children who attended the five-year-old dental review clinic at the South Thames cleft service over a four-year period. Records of 162 children were analysed. RESULTS Unilateral CLP was the most common type of cleft. Two-thirds (65%) of the children in this service evaluation had developmental defects of enamel affecting the upper incisors. A third (32%) had enamel hypomineralisation. Between 90% and 100% of children over the four-year study period were registered with a dentist. Regular fluoride varnish application was received by 64% to 81% of children and toothpaste with an appropriate concentration of fluoride was used by 72% to 91% of children. CONCLUSIONS Improvements in shared care arrangements between primary dental care clinicians and specialist paediatric dentists are needed to ensure that caries risk is reduced in children born with CLP. This allows the specialist dental services to focus on the complex dental issues that are seen more frequently in CLP and often require a multidisciplinary approach.

The structure and prevalence of superficial carious and non-carious lesions of permanent and deciduous enamel in children who presented for routine dental care in various districts of St. Petersburg

Relevance. To increase the effectiveness of prevention and treatment protocols, it is above all necessary to consider the activity of caries, especially at the early enamel lesion stage, in the form of a white spot, to make the correct diagnosis based on a clinical examination, which assesses the location, change in surface hardness, symmetry, contour shape, depth, color and opacity of the lesion. Different causes of superficial enamel discoloration, in the form of white spots, are paramount for the restorative treatment as the quality of the enamel preparation affects the marginal fit and the durability of the restoration. However, poor oral hygiene, disturbance in eating behavior affect the course of non-carious hard-tissue diseases, which caries may complicate. Purpose – to optimize the diagnosis of initial dental enamel lesions to improve the caries prevention quality.Materials and methods. The study examined 460 children living in the Central and Krasnoselsky districts of St. Petersburg. The following indices assessed hard tissue condition: OHI-S, Greene and Vermillion; OHI by O'Leary T., Drake R., Naylor; White spot lesions index, Gorelick L, Geiger A. M, Gwinnett A. J., DMFT and df; caries activity.Results. The total prevalence of superficial (initial) lesions of hard tissues was 37.82%, i.e. 174 people out of 460 examined patients had superficial enamel lesions according to the criteria of I and II categories. The study found enamel changes in the age groups: 5-6 years (130) – 36 people (27.69%); 12 years old (175) – 62 people (35.42%); 15 years old (155) – 76 people (49.03%).Conclusions. Focusing on the caries activity signs rather than a precise differential diagnosis of the lesion nature is necessary to provide well-timed treatment and prevention upon detecting initial enamel lesion at a dental check-up.

Risk factors for developmental defects of enamel in children from southeastern Brazil.

Developmental Defects of Enamel (DDEs) comprise qualitative and/or quantitative changes to the enamel during amelogenesis. The aetiology of DDE remains inconclusive. To determine the association of pre, peri, and postnatal factors with the presence of DDE. Cross-sectional study with 353 children (8 to 11 years-old) in a Brazilian town. One calibrated dentist assessed DDE using the Developmental Defects of Enamel Index and a questionnaire collected medical and sociodemographic data. Children with at least one type of DDE were categorized into the DDE group. Subtypes of DDE were also recorded. 63.1% of children had at least one type of DDE. Diffuse opacity was present in 36.7%, demarcated opacity in 14.8%, and hypoplasia in 5.83% of the children. In multivariate analysis, demarcated opacities and hypoplasia were associated with birth weight ⟨ 2500g (OR = 4.82; 95% CI 1.23-1.95). Low birth weight predicted DDE.

Prevalence of developmental defects of enamel in children visiting a university hospital in Chennai - a retrospective study

Prevalence of developmental defects of enamel in children visiting a university hospital in Chennai - a retrospective study

Comprehensive approach to treatment of malocclusion in children with different degree of caries resistance

Relevance.Skeletal malocclusion stands at the head of all oral diseases and is encountered in 32-35% of children and adolescents in Russia [7;12;15]. The number of malocclusions has increase due to various reasons, one of which is early extraction of deciduous carious teeth resulting in impaired vertical dimension and occlusion of teeth [1;14]. Diagnosis with due regard to caries resistance degree and planning of respective operative and orthodontic treatment are indispensable in children with skeletal malocclusion. Purpose– to increase effectiveness of functional treatment of malocclusion in children with various degree of caries resistance.Materials and methods.There were examined 108 patients aged between 6 and 16 with Class I malocclusion according to Angle, abnormal arch-to-arch relationship and tooth position and various degree of caries resistance. 4 groups were formed: high, sufficient mean, decreased mean and low caries resistance of dental enamel. Intensity of carious process was detected in all patients before and after orthodontic treatment. The effectiveness of reminerlization administered by removable orthodontic appliances was evaluated by electrometrical testing of hard dental tissue. Surface EMG was used to assess normalization of tone of maxillofacial muscles in children by average amplitude of biopotentials of superficial masseter and temporalis muscles.Results.Сhanges in caries intensity in children after treatment with removable orthodontic aligners indicate the necessity for remineralization of hard dental tissues during orthodontic treatment and it is confirmed by decrease of electroconductivity of enamel in children with sufficient mean, decreased mean and low degree of dental enamel caries resistance. Increase of biopotential mean amplitude during «total mastication» for masseter and temporal muscles confirms effectiveness of preformed elastic positioner along with myodynamic exercises.Conclusions.The conducted study proves the necessity of comprehensive approach with procedures increasing the degree of caries resistance of hard dental tissues during orthodontic treatment of skeletal malocclusion in children.

Prevalence of Dental Caries and Dental Defects of Enamel in Children Aged 3 to 5 Years-Old from Salvador- BA, Brazil, 2018

Prevalence of Dental Caries and Dental Defects of Enamel in Children Aged 3 to 5 Years-Old from Salvador- BA, Brazil, 2018

Compositional and micromorphological features of hypoplastic enamel in children’s permanent teeth

Enamel hypoplasia is the most common disease of hard tooth tissues of non-carious origin emerging before their eruption. It develops as a result of a delayed and perverse function of ameloblasts leading to the violation of the processes of formation and mineralization of tooth protein structures. The clinical manifestations of enamel hypoplasia are spots, defects in the form of pits, cup-shaped depressions, grooves on various surfaces of child’s teeth. The work is devoted to a comparative investigation of microstructural and compositional features of intact and hypoplastic enamel in children’s permanent teeth using analytical scanning electron microscopy with energy-dispersive X-ray spectroscopy. The hypoplastic enamel is enriched in organic substance and has an irregular structure without keyhole-shaped prismatic structure. Mineral deposition is indicated for hypoplastic enamel including hydroxyapatite with globular structure and calcite and halite, which might have been caused by the violation of extracellular local environment probably due to the enamel hypoplasia development.

The Importance of Preserving the Primary Teeth before the Permanent Teeth Eruption

One of the important factors of referring children to dentistry is dental caries in the primary teeth. It is commonplace to see moments of anxiety for both the child and their parents when a tooth decays happen. It should be noted that the thickness of enamel in children is little, which is one of the factors that affect dental caries to develop more easily. In order to prevent the dental decay of primary teeth, there are several ways in which a dentist can present in order to guide the child and their parents into the right preventive path.

Erosive Effect of Aspirin on Primary Teeth Enamel in Children with Heart Disease (An In vivo study)

Erosive Effect of Aspirin on Primary Teeth Enamel in Children with Heart Disease (An In vivo study)

THE ROLE OF COMPLEX OF PROPHYLACTIC ARRANGEMENTS WITH THE USE OF REMINERALIZING PREPARATION AS TO ENAMEL RESISTANCE IN CHILDREN WITH DISORDERS OF TEETH FORMATION

Aim of research: To increase the resistance of teeth enamel in children with disorders of their formation by introduction of the complex of prophylactic arrangements using remineralizing preparation. Materials and methods. The object of research is the zones of injured enamel (on the background of hypoplasia) of permanent teeth. The subject is the level of general calcium and orthophosphates in acid biopsy materials of injured teeth enamel. Methods of research: the vital coloration of enamel, transillumination, acid biopsy of enamel, photometric, statistic. There was carried out the determination of level of calcium and orthophosphates in acid biopsy materials of injured enamel in 45 children, 6–12 years old with enamel hypoplasia. The group № 1 (21 persons) – children who underwent the complex of prophylactic arrangements that included recommendations as to the choice of means and subjects for oral cavity care and teaching the standard method of teeth brushing. The group № 2 (24 persons) – children, who additionally used remineralyzing cream on the water base with casein phosphopeptide – amorphous calcium phosphate (СРР-АСР) (Certificate on the state registration №10014/2010 of 03.12.2010). Results. In children with chronologic enamel hypoplasia was established the low level of calcium and orthophosphates in acid biopsy materials of injured enamel. Calcium/phosphorus (Са/Р) coefficient in examined groups № 1 and № 2 was 1,26±1,14 and 1,19±0,56, respectively. The high effectiveness of the offered complex of prophylactic arrangements (teaching the hygienic habits – group №1, additional use of remineralizing cream – group № 2) is proved by the growth of macroelements content in acid biopsy materials of injured enamel in examined children. The holding of prophylactic arrangements in children of the group № 2 using remineralizing cream, favored the more essential growth of level of calcium and orthophosphates in biopsy materials comparing with group of children № 1 (р=0,002 and р=0,03, respectively), and also reliably increased Са/Р coefficient (р=0,0005). Conclusions. Introduction of complex of prophylactic arrangements using remineralizing preparation in children with disorders of teeth formation favored the rise of enamel resistance as a result of growth of the level of calcium and orthophosphates in its mineral component.