The present paper presents experimental evidence confirming that contextually mismatching scalar implicatures can be generated even when quantifiers range over empty domains. In the literature, this possibility has been interpreted as providing further evidence for a grammatical approach to scalar implicatures. The main result presented here is that scalar sentences with empty domains are judged as more infelicitous when associated with a mismatching implicature than variants with the same empty domains but associated with a non-mismatching implicature. We interpret this result as suggesting that the infelicity judgment associated with the first kind of sentence stems from the cumulative effect of the mismatching implicature and the contextual domain emptiness. Compared to previous literature on blind implicatures, our results indicate that the body of knowledge involved in relevance assignments is restricted to ignoring existential determination while still considering the properties attributed to nonexistent entities. They also show that, while not blocking implicature generation, contextual domain emptiness plays a role in speakers’ evaluation of scalar sentences, reflecting the unconscious nature of scalar implicature generation.