Pediatric Emergency Research Articles

X-ray Utilization Patterns in Pediatric Musculoskeletal Trauma: Assessing Potential Overprescription

Background: Traumatic injuries are among the leading causes of visits to the pediatric emergency department (PED). Objectives: This study aims to evaluate the pediatric approach to musculoskeletal trauma in children to determine whether the routine use of X-rays can be reduced by encouraging the use of ultrasound. Methods: This retrospective observational study included children aged 0 - 18 years admitted to the PED of the Policlinico A. Gemelli with a diagnosis of musculoskeletal trauma from January 2017 to December 2021. Patients were divided into two groups based on the presence of fractures identified through radiological examinations: "Fracture Yes" and "Fracture No." Data on X-rays performed were categorized according to the site of trauma. Results: A total of 5972 children were enrolled. The most notable findings concern the regions of trauma. Among 1273 patients who underwent X-rays of the hand region, 617 (48%) showed fractures, and 656 (51%) did not. Of the 744 X-rays performed for the foot region, 235 (31%) revealed fractures, while 509 (68%) were negative for fractures. In the upper limbs region, 1334 X-rays were performed, with 1079 (80%) identifying fractures and 255 (20%) showing no fractures. For the lower limbs region, 479 X-rays were conducted, 204 (42%) of which revealed fractures, while 275 (58%) were negative for fractures. All these results demonstrated statistically significant differences (P < 0.05). Conclusions: Despite the limitations of the study's retrospective design and its single-center setting, the findings highlight a high prevalence of X-rays in the hand and upper limb regions, often with positive results. In contrast, radiography of the lower limbs and feet frequently yielded negative findings, suggesting potential overuse. Future research should investigate the clinical utility of musculoskeletal ultrasound as an alternative imaging modality to minimize unnecessary radiation exposure in pediatric patients.

Hiperplasia sebácea ectópica en el labio inferior

Ectopic sebaceous hyperplasia is a very rare condition that may be encountered in paediatric care or emergency care settings. It may be confused with more common clinical conditions, possibly resulting in misdiagnosis, performance of unnecessary tests or inadequate treatment. We present a case that demonstrates that the correct identification of the lesions and a watchful waiting approach allowed their spontaneous resolution without sequelae of any kind.

Pulmonary tuberculosis presenting with tubercular myocarditis and shock in an adolescent child

ABSTRACT Involvement of the heart in children with tuberculosis (TB) generally affects the pericardium; however, the myocardium of a child being affected alone and leading to systolic heart dysfunction has rarely ever been reported. We report a case of a 12-year-old child who presented to Pediatric Emergency Services with severe hypotension (BP <5th percentile for the age) and was subsequently diagnosed with severe left ventricular (LV) dysfunction, with an ejection fraction of less than 15%. During the hospital stay, after an exhaustive workup, the child was diagnosed with pulmonary TB with tubercular myocarditis. The child was managed with anti-tubercular treatment (ATT) and was followed up regularly for monitoring of ejection fraction with echocardiography. The LV systolic function improved, with the ejection fraction increasing to 55%-60% at 3 months. The child is still on regular follow-up, has completed 6-month course of ATT, and is doing well.

A Pilot Study of a Simulation-Based Mastery Learning Procedural Curriculum for Pediatric Emergency Medicine Fellows.

Pediatric emergency medicine (PEM) fellows are expected to perform high-risk procedures across a wide range of patient age, size, and physiology including procedures that are no longer required during pediatric residency training. Examples include central venous catheter (CVC) placement, endotracheal intubation of children and adolescents, and tube thoracostomy placement. Simulation-based mastery learning has demonstrated decreased patient morbidity. In this study, we describe implementation of a simulation-based mastery learning (SBML) procedural curriculum for PEM fellows. Our PEM fellows underwent an SBML procedural curriculum for lumbar puncture (LP), CVC placement, endotracheal intubation, and tube thoracostomy placement. These procedures are mandatory for fellows to learn, have known association with potential iatrogenic injury, and are widely available commercial task trainers. Fellows underwent baseline assessments, group demonstration, deliberate practice, and then postassessments. For both pre- and postassessments, we used internally developed checklists with minimum passing scores (MPSs) calculated by the Mastery-Angoff technique. Nineteen pediatrics residency-trained PEM fellows underwent this curriculum over a 2-year period. Six fellows (31.58%) achieved the MPS on all four procedures during their first posttest attempt. All fellows achieved the MPS on all four procedures by the second posttest attempt. Most fellows (17/19 or 89.47%) did not achieve the MPS on baseline LP assessments, despite inclusion of this procedure as an Accreditation Council of Graduate Medical Education (ACGME) requirement during their pediatric residency training. All participating PEM fellows demonstrated competency after training on four procedures associated with iatrogenic injuries. Using an SBML framework is a feasible method to teach procedural skills to PEM fellows, allowing them to demonstrate objective measures of competency in the simulation laboratory.

Guideline on the Use of Intravenous Ketamine for Procedural Sedation in the Children's Emergency Department: A Quality Improvement Project.

In pediatric emergency medicine, sedation is crucial for performing some therapeutic procedures in children. Ketamine is still not widely used, despite being the preferred agent due to its effectiveness and safety profile. Implementing a guideline for intravenous ketamine in emergencies requiring procedural sedation in children, as well as training and evaluating staff competencies in performing this procedure, are the aims of this study. Senior and mid-level physicians, including pediatric nurses working in the children's emergency department (ED), have easy access to this concise repository for carrying out this procedure safely and effectively. The main objective was to implement a policy (guideline) for sedation in the children's ED. The secondary objectives were to determine whether the introduction of this policy increased the overall satisfaction rating of procedural sedation as a service offered in the Trust, to close skillgaps among staff through targeted training, and to assess the degree of recommendation for this ongoing standard of practice, in line with the current best evidence. A retrospective review of pediatric sedation cases with fractures in the children's ED of Buckinghamshire Healthcare National Health Service (NHS) Trust was conducted between June 2022 and August 2023. Surveys were sent out to assess attitudes, sedation skills, and compliance with the Royal College of Emergency Medicine (RCEM) guidelines. A policy for pediatric sedation with intravenous ketamine was later created and put into effect. Pre- and post-intervention data were compared to assess changes in sedation competency, compliance, and confidence. Out of the 103 pediatric fracture cases reviewed, 16 were identified as needing reduction upon initial evaluation, based on the child's condition at presentation. However, only one (6%) was treated with ketamine sedation in the children's ED, whereas nine cases (56%) were reduced under general anesthesia. The remainder was treated with varying use of nitrous oxide gas (Entonox) and diamorphine. Significant progress had been made after a clinical guideline for intravenous ketamine-assisted sedation in children was put into practice. Physicians reported improved knowledge of sedation techniques, knowledge of airway control, and safety in administering ketamine sedation. The percentage of respondents supporting the guidelines increased from 61% before the intervention (nValue=11) to 94% after (nValue​=17), using various metrics. These results demonstrated how well evidence-based policies and training can improve performance, competence, and safety. The use of procedural sedation in the children's EDincreased and the need for general anesthesia was significantly reduced after a uniform pediatric ketamine sedation policy was implemented. Targeted training to address skillgaps increased employee confidence and adherence to best practices.

KNOWLEDGE AND SKILLS IN MANAGEMENT OF COMMON PAEDIATRIC EMERGENCIES AMONG HEALTH WORKERS IN PRIMARY HEALTH CARE CENTRES IN ZARIA

Every day, Nigeria witnesses the loss of approximately 2,300 children under the age of five, primarily due to preventable and treatable conditions such as pneumonia, malaria, and diarrhoea. These high mortality rates are disproportionately higher in rural areas compared to urban regions, where primary health care (PHC) centres often represent the only accessible medical services. Given that PHC centres serve as the first point of contact with the healthcare system for most Nigerians, it is imperative to assess the capabilities of health workers in these facilities, particularly in the management of paediatric emergencies. This study aimed to evaluate the knowledge and skills of health workers in PHC centres in Zaria concerning the management of common paediatric emergencies. A cross-sectional descriptive study was conducted among 139 health workers in PHC centres, randomly selected through a multi-stage sampling technique from both Sabon Gari and Zaria Local Government Areas. Data collection was performed using a pre-tested, semi-structured, self-administered questionnaire. The collected data were analysed using SPSS version 21, with the chi-square test applied to assess associations, and results presented in tables and charts. The findings revealed a generally low level of knowledge and skills in managing common paediatric emergencies among the health workers surveyed. Specifically, 66 (48.5%) of the respondents exhibited very poor knowledge of the causes of common paediatric emergencies, 32 (23.5%) had poor knowledge, 34 (25.0%) demonstrated good knowledge, and only 4 (2.9%) had excellent knowledge. In terms of treatment knowledge, 46.7% of respondents had very poor knowledge, 34.1% had poor knowledge, 16.3% had good knowledge, and only 3.0% had excellent knowledge. Diagnostic skills were similarly deficient, with 41 (37.3%) of respondents displaying very poor skills, 39 (35.5%) poor skills, 26 (23.6%) good skills, and only 4 (3.6%) exhibiting excellent skills. Additionally, 24.8% of respondents had very poor skills in the treatment of paediatric emergencies, 42.3% had poor skills, and 32.8% had good skills, with none achieving excellent skills. A statistically significant relationship was observed between academic qualification and knowledge of causes (p=0.004) and treatment (p=0.000), as well as between academic qualification and diagnostic skills (p=0.006). The pervasive low level of knowledge and skills among PHC health workers is alarming, particularly given Nigeria's already dire childhood mortality statistics. These findings underscore the urgent need for a strategic partnership between the Department of Paediatrics at Ahmadu Bello University Teaching Hospital and the Department of Primary Health Care in Zaria and Sabon Gari Local Governments. Such collaborations could facilitate quarterly training sessions and workshops aimed at enhancing the management of paediatric emergencies in these critical frontline health centers.

Measurement Properties of the Pediatric Anesthesia Emergence Delirium Scale: A Confirmatory Factor Analysis-Based Study.

Emergence delirium is a well-known and common problem in children recovering from anesthesia. The five-item Pediatric Anesthesia Emergence Delirium scale is one of the most commonly used instruments for assessing this condition, but the scale has been questioned regarding its latent structure, i.e., whether its items cover just one underlying construct. It has been suggested that the scale's first three items might identify emergence delirium better than the last two. The aim of this study was to evaluate the measurement properties of the Pediatric Anesthesia Emergence Delirium scale with a focus on its latent structure and cutoff scores, using appropriate statistical methods for ordinal data. A total of 350 children under 7 years of age, undergoing adenoidectomy, with or without additional tonsillotomy or minor procedures like paracentesis, tongue-tie release, or cerumen removal, were enrolled in the study. At the recovery unit, emergence delirium and pain were registered. The confirmatory factor analyses demonstrated that the two-factor model, including emergence delirium-specific behaviors (first three items) and emergence delirium-nonspecific behaviors (last two items), established an excellent model fit according to the χ2 goodness-of-fit statistics, Root Mean Square Error of Approximation, Comparative Fit Index, Tucker-Lewis Index, and Standardized Root Mean Square Residual. The ordinal alpha of 0.98 and the ordinal omega of 0.96 supported the internal consistency reliability of the emergence delirium-specific behaviors. The convergent validity was supported due to a strong correlation between emergence delirium-nonspecific behaviors and the Face, Legs, Activity, Cry, and Consolability scale. The receiver-operating characteristic curve analyses resulted in two tentative cutoff scores for emergence delirium-specific behaviors¸ ≥ 6 and ≥ 8. The Pediatric Anesthesia Emergence Delirium scale's first three items are a more valid and reliable measure of emergence delirium than its original five items.

A novel blended and interprofessional approach to pediatric emergency training: self-assessment, perception, and perceived long-term effects

BackgroundWe developed a blended training program at a tertiary pediatric center based on hospital-specific emergency guidelines, profession-specific Virtual Patients (VPs), and interprofessional team training. Using this novel approach, we addressed differing educational needs of medical and nursing staff and intrinsic cognitive overload among participants, aiming for harmonization of in-house emergency proceedings.MethodsSelf-assessments of pediatric emergency knowledge and skills were conducted before (T1) and after (T2) preparation using VPs, as well as after the team training day (T3). At T3, participants completed questionnaires on the training approach, its components, and learning impact. Ten months after the training, a follow-up survey (T4) queried perceived benefits within and beyond emergency situations.ResultsA total of 56 medical staff and 56 nursing staff members participated in the pilot phase. Of these, N = 55 (98%) and N = 48 (85%), respectively, returned self-assessments; questionnaires were completed by N = 55 (98%) and N = 51 (91%), respectively. In both groups, 57 participants (50.9%) completed the follow-up survey. After team training (T3), both groups had statistically significant increased knowledge and skill scores compared with those at T1. Regarding the blended approach and its components, medical and nursing staff alike rated the entire course and its guidelines, the preparatory VPs, and the team training very highly. Participants felt being better prepared for pediatric emergencies. Perceived strengths of the training approach were in the triangulation of teaching methods and its interprofessionalism. More training scenarios were requested, as well as recurrent training. In the follow-up, participants reported improved confidence and calmness, as well as improved communication and collaboration when involved in an emergency. Beyond emergencies, benefits were reported in daily routines.ConclusionsOur blended approach was perceived as being effective in improving preparedness among medical and nursing house staff. This approach permits customization of content and deliberate practice to improve pediatric critical care.

Single centre implementation of the Paediatric Anaesthesia Emergence Delirium scale.

Early recognition of paediatric emergence delirium (ED) by post-anaesthesia care unit (PACU) nurses is critical for the effective management and prevention of complications. This project aimed to enhance nursing education and standardise the use of the Paediatric Anaesthesia Emergence Delirium (PAED) scale as a reliable tool for assessing ED. This project involved an educational intervention for PACU nurses to train them in using the PAED scale for ED evaluation. The effectiveness of the PAED scale was compared with the more commonly used Face, Legs, Activity, Cry, Consolability (FLACC) scale in the evaluation of postoperative paediatric patients. An educational programme was designed for PACU nurses, with pre-and post-surveys administered to assess the impact of the educational intervention on their knowledge, confidence, and familiarity with ED and the PAED scale. This project included time trials comparing the use of the PAED and FLACC scales during patient simulations after the educational intervention. Following the educational programe, nurses demonstrated increased confidence and familiarity with ED and the PAED scale. Furthermore, the use of the PAED scale following the educational intervention significantly reduced the time required to evaluate patients and initiate treatment for ED compared with the FLACC scale. Equipping nurses with the knowledge and skills to effectively implement the PAED scale improves ED's timely recognition and treatment, leading to safer, more efficient care for postoperative paediatric patients. This project demonstrates the importance of evidence-based tools and targeted nursing education.

Variability in choosing to report child maltreatment cases by pediatric emergency medicine physicians

BackgroundChild maltreatment is a significant public health problem. Emergency departments are often the first contact points for suspected child maltreatment. Variability in the decision of whether or not to report maltreatment cases to Child Protective Services (CPS) may lead to missed opportunities for diagnosis and intervention or unnecessary medical and social interventions. ObjectiveTo evaluate the variability in choosing to report child maltreatment cases among emergency department physicians. Participantsand Setting: Our survey was conducted on Emergency physicians through the PED-EM-L@LISTSERV.BROWN.EDU listserv MethodsWe queried emergency physicians with a 19-question survey. Seven clinical scenarios were designed by our Pediatric Emergency division in consultation with a child abuse specialist. Scenarios were created with varying degrees of suspicion for child maltreatment. Our survey asked physicians if they would report each case to CPS. We collected demographic information regarding the physician, their work setting, and their patient population. The responses for individual scenarios were analyzed as percentages and compared with demographic data by Fisher's exact test. Our survey received 307 responses. ResultsMost of our 307 respondents are specialized in pediatric emergency medicine (95.6%). Of the seven scenarios, physicians near-unanimously (99.3%, 95% CI 97.9–99.9%) agreed in only one scenario. For the other six scenarios, agreement ranged from 54.4% (95%CI: 48.8–59.9%) to 80.1% (95%CI: 75.4–84.3%). Demographics, including physician age, gender, ethnicity, years of experience, population ethnicity, and hospital location, did not explain variability in choosing to report to CPS. ConclusionOur study shows significant variability in reporting child maltreatment cases, not explained by hospital or physician demographics.

Use of Intraosseous Access in the Pediatric Emergency Department: A Single Center Experience

Use of Intraosseous Access in the Pediatric Emergency Department: A Single Center Experience

Outbreak of Acute Fulminant Myocarditis in Children in Campania Region, Italy: A Case Series

Acute fulminant myocarditis is a rare event in children, accounting for about 10% of all cases of acute myocarditis. Its lack of specific onset patterns and unpredictable evolution make diagnosis and prompt treatment challenging. We observed six cases of fulminant myocarditis admitted to our Pediatric Emergency Unit (Campania region, Sothern Italy) within a very short timeframe (50 days, from July to September 2024). Three of them died, and two are still under treatment in a Pediatric Cardiologic Intensive Care Unit in critical condition. In only one case, cardiac function improved. The described cases were not geographically linked, belonging to different areas of Southern Italy. No common etiological agent was found. Given the relatively low incidence of the condition, the occurrence of six pediatric myocarditis within approximately two months should be considered exceptional. Careful monitoring of further cases in the next few months should be warranted.

Prescription practice and yield of chest radiography in the management of children presenting to the French pediatric emergency department with non-traumatic chest pain

ObjectivesChest pain is a common symptom in pediatric emergency department. The causes are mostly benign without any sign on chest x-ray (CXR). However, CXR is one of the most ordered tests in this situation. Our main objective was to assess the current management of CXR by physicians in this context, according to the algorithm proposed by the French Society of Pediatrics (FSP). Materials and methodsWe conducted a retrospective study in two French pediatric emergency departments. We reviewed the medical records of children who presented with chest pain between 2018, July 1rst to 2021, July 31th. We collected data from history and clinical examination. The prescription of CXR and its interpretation were collected. ResultsOverall, 599 children were enrolled. The algorithm was followed in 57,1 % of cases, and 8,2 % of abnormal CXR were noted. On univariate analysis, medical history with a significant OR greater than 2 included cardiological history (as defined by FSP), neoplasia, pneumonia and sickle cell disease. Right lateralized pain, pain that worsens with respiration, fever and cough were also symptoms significantly associated with an abnormal CXR result. On physical finding, tachycardia, tachypnea, abnormal cardiac and pulmonary clinical examination (as defined by the FSP) were significantly associated with pathological CXR. However, the multivariate logistic regression model could not be carried out due to too many significant variables in univariate analysis, and too few number of abnormal CXR reported. ConclusionCXR remains the cornerstone of chest pain management in pediatric emergencies, even though the rate of abnormal CXR appears low. The appropriateness of CXR prescribing can be improved by guidelines focusing on the clinical etiologies of chest pain visible on CXR. A similar prospective study may identify risk factors for pathological CXR and clarify the decision tree for the indication of CXR in chest pain.

Pediatric Emergency Department-based Food Insecurity Screening During the COVID-19 Pandemic

Pediatric Emergency Department-based Food Insecurity Screening During the COVID-19 Pandemic

Assessment of Continuous Pulse Oximetry Monitoring in Infants With Bronchiolitis in the Pediatric Emergency Department: A Cross-Sectional Study

Assessment of Continuous Pulse Oximetry Monitoring in Infants With Bronchiolitis in the Pediatric Emergency Department: A Cross-Sectional Study

Lung Ultrasound Findings in Children With Asthma Exacerbations.

We sought to assess whether the presence and extent of lung ultrasound (LUS) findings were associated with asthma exacerbation severity in children. We enrolled a convenience sample of patients aged 5-18 years presenting with acute asthma exacerbation to a tertiary care pediatric emergency department. Severity of an asthma exacerbation (mild, moderate, severe) was assessed within 1 hour of the LUS using the Hospital Asthma Severity Score, a validated asthma assessment tool. LUS was performed by trained pediatric emergency providers. The presence of LUS findings (B-lines, consolidations, pleural effusion, and pleural line abnormalities) was assessed using a standardized criterion based on consensus guidelines. A total of 111 patients with a median age of 8 years (interquartile range 6-12) were enrolled. LUS was positive in 57% of patients. Pleural line abnormalities were observed in 34%, B-lines in 29%, consolidations <1 cm in 24%, and consolidations ≥1 cm in 7%. Patients with moderate and severe asthma exacerbations were more likely to have any B-lines (31% and 43%, respectively) than patients with mild exacerbations (12%; P = .021); however, the presence of ≥3 B-lines or confluent B-lines did not differ across severity groups. The presence of other findings did not differ based on asthma severity. LUS findings are observed in a substantial portion of children presenting with asthma exacerbations. B-lines were the only LUS finding significantly associated with asthma severity, while lung consolidations <1 cm and >1 cm were not correlated with severity. These findings provide valuable information for the diagnostic use of LUS in pediatric patients with asthma exacerbation.

A randomized clinical trial of intranasal dexmedetomidine versus inhaled nitrous oxide for procedural sedation and analgesia in children

BackgroundProcedural sedation and analgesia is an important part of pediatric emergency care, safe and clinically useful alternatives for adequate management are necessary. The objective of this clinical trial was to evaluate the non-inferiority of intranasal dexmedetomidine to nitrous oxide with respect to analgesia for a painful procedure in children 3–15 years of age.MethodsThis prospective, equally randomized, open-label, non-inferiority trial was conducted at a Pediatric Emergency Department. Previously healthy children 3–15 years of age, with an extremity fracture or luxation or a burn and requiring procedural sedation and analgesia were eligible. Patients were randomized to receive either intranasal dexmedetomidine or inhaled nitrous oxide. The primary outcome measure was highest pain level during the procedure, assessed with Face, Legs, Activity, Cry, Consolability scale (FLACC). Mann-Whitney U test (continuous variables) and Fisher’s test (categorical variables) were used for statistical analysis.ResultsThe highest FLACC was median 4 (IQR 3–6) with intranasal dexmedetomidine and median 4 (IQR 2–6) with nitrous oxide. The median of the difference between samples from each group for FLACC was 0 with 95%CI (0–1), thus intranasal dexmedetomidine was not inferior to nitrous oxide with respect to the level of pain during the procedure. The same method for procedural sedation and analgesia would be accepted by 52/74 (82.5%) children and 65/74 (91.5%) parents in the intranasal dexmedetomidine group respectively 59/74 (88.1%) versus 70/74 (94.6%) with nitrous oxide. No serious adverse events were reported.ConclusionsThe results of this trial support that intranasal dexmedetomidine is not inferior to 50% nitrous oxide in providing analgesia for a painful procedure in children 3–15 years of age and can be considered as an alternative to 50% nitrous oxide for procedural sedation and analgesia.Trial registrationEudraCT 201,600,377,317, April 20, 2017. https://eudract.ema.europa.eu/.

Caregiver Perspectives and Preferences Regarding Timely Access to Unscheduled Acute Care in Paediatric Urgent Care Centers: A Qualitative Evaluation of Save My Spot Tool.

Explore caregiver (i.e., person who provides direct care for a child and was present at the time of their medical visit) perspectives and preferences regarding timely access to unscheduled acute care as well as barriers and facilitators of the use of an online appointment tool (i.e., Save My Spot) in a satellite children's hospital five urgent care centers in the United States. A descriptive qualitative interview study. We conducted semi-structured interviews with 49 caregivers in a private room, in person and in conjunction with medical visits from June 2023 to the end of August 2023 after obtaining institutional ethical approvals. We employed deductive and inductive content analysis and used the MAXQDA data analysis tool. Average caregiver age was 37 years. Most of the caregivers were female, white, and non-Hispanic and had low income. We identified three categories: (a) Caregiver preferences for using the Save My Spot online appointment tool and their reasons for buy-in, (b) ways of promoting the Save My Spot tool and (c) enhancing the accessibility of the Save My Spot tool. The findings of this study suggest that when introduced successfully, caregivers adopt an online appointment tool and find it efficient in minimising wait times. Various approaches (e.g., social media, billboards) can be used to promote the tool to increase timely access to care. This study provides valuable insights into the utilisation of an online appointment tool in the two hospital-based and three stand-alone neighbourhood urgent care centers of a large urban children's hospital. Future studies capturing different tools and populations are recommended to gain diverse understanding. The study was reported following the Standards for Reporting Qualitative Research. Caregivers provided their perspectives and the Paediatric Emergency Medicine Disparities Working Group contributed to the interpretation of the study findings.

Testing and Treatment Thresholds for Pediatric Pneumonia in the Emergency Department.

Clinical prediction models for pediatric community-acquired pneumonia (CAP) may standardize management. Understanding physician risk thresholds is important for model implementation. We aimed to elucidate physician-derived thresholds for chest radiograph performance and empirical antibiotic treatment of CAP among children presenting to the emergency department with respiratory illness before and after knowledge of results of a validated clinical prediction model. Pediatric emergency physicians were surveyed through the American Academy of Pediatrics Pediatric Emergency Medicine Collaborative Research Committee and provided 8 clinical vignettes for children with respiratory symptoms. Respondents were asked to indicate their probability of radiographic CAP and choose whether they would obtain a chest radiograph or give empirical antibiotics before and after being provided with the probability of radiographic CAP based on a validated prediction model. We used logistic regression to establish testing and treatment thresholds, defined as the disease probability at which half of physicians acted. Two-hundred and eight (44.3%) of 469 physicians completed the survey. Most were attending physicians (96.0%) practicing in a freestanding children's hospital (76.8%). Testing and treatment thresholds for CAP were 17.6% (95% confidence interval [CI] 16.4% to 18.8%) and 66.1% (95% CI 60.1% to 72.5%), respectively, before knowledge of the model-estimated probability. With knowledge of the prediction model, testing and treatment thresholds were 13.5% (95% CI 12.3% to 14.7%) and 58.0% (95% CI 53.2-62.8). We elucidated physician thresholds for testing and treatment of CAP, which may be integrated into future pneumonia risk models to improve acceptability and incorporation into practice.

Oral Ketamine and Midazolam for Procedural Sedation in the Pediatric Emergency Department: A Retrospective Study.

Needle-free procedural sedation (PS) is an attractive option for children presenting to the emergency department (ED) who require a painful procedure, as it avoids inflicting additional pain either with intravenous line placement or intramuscular injection. While use of oral (PO) ketamine has been reported in the literature, limited information is available to guide ED-based use in children. This is a descriptive study of the patient experience receiving PS with the following regimen: PO ketamine 6 mg/kg (max of 200 mg) with or without PO midazolam 0.5 mg/kg (max 15 mg) approximately 30 minutes before a procedure. We performed a retrospective chart review of children younger than 18 years receiving this PS regimen at a tertiary care children's hospital ED and an affiliated community hospital ED from January 1 through September 30, 2023. Fifty-eight children were sedated with PO ketamine during the study period. The most common procedure performed was laceration repair (46.5%), followed by incision and drainage (17.3%). All but 2 children received PO midazolam along with PO ketamine. Eight patients received additional medications due to inadequate sedation. Sedation depth was clinician-reported as moderate in 74.1% (43), mild in 15.5% (9), and deep in 10.3% (6). Procedures were completed in 98.3% (57) cases. 93.1% (54) of patients had no adverse event (AE) of any kind and no patient had a significant adverse event (SAE). PO ketamine with or without midazolam resulted in procedure completion of a variety of procedures in the pediatric ED with minimal AE, no SAE, and without need for additional sedative medications in 86.2% (50). This regimen is an option for needle-free moderate PS in this setting. Further study is needed to clarify the benefit of the addition of midazolam to PO ketamine, rates of AE and SAE, sedation duration, and recovery times.