1. Jeffrey Lancaster, MD* 2. Jessica Lear, MD* 3. Richard Brant, MD* 4. Brian Riedel, MD* 5. Joseph Minardi, MD† 1. *Department of Pediatrics, West Virginia University School of Medicine, Morgantown, WV 2. †Departments of Emergency Medicine and Medical Education, West Virginia University School of Medicine, Morgantown, WV A 70-day-old female infant presents to the emergency department (ED) with a 1-month history of abdominal distention and constipation. The patient was born at term via vaginal delivery. She is formula fed with a cow milk protein formula and routinely consumes 4 oz every 4 hours. She passed meconium within 24 hours after birth. However, since that time she has not stooled regularly, and her parents have administered daily diluted fruit juices and enemas every other day to promote defecation. Despite these interventions, her abdomen has become more distended, and the parents report that her constipation continues. In the ED her vital signs are temperature 98.6°F (37.0°C), blood pressure 111/62 mm Hg, pulse 137 beats/min, respiratory rate 22 breaths/min, and oxygen saturation 100% on room air. Her examination shows a well-appearing baby in no apparent distress. Her cardiopulmonary examination findings are normal. Extremity examination shows capillary refill within 2 seconds, and there is no appreciable edema. Peripheral pulses are strong. The patient’s abdomen is distended but nontender and without any cutaneous findings suggesting portal hypertension. Bedside abdominal ultrasonography performed by the ED physician demonstrates ascites without any organomegaly (Fig 1). She is admitted to the pediatric service at that time. Figure 1. Ascites is seen in the pelvis surrounding multiple intestinal loops. Results of laboratory studies are largely normal (aspartate aminotransferase, alanine aminotransferase, albumin, electrolyte panel, and lipase) except for peripheral eosinophilia noted on the complete blood cell count (white blood cell count, 10,500/μL [10.5 × 109/L]; eosinophils, 15%; absolute eosinophil count, 1.5 × 109/L). The total serum immunoglobulin E (IgE) level is normal at …
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