ABSTRACT The emergence of the COVID-19 pandemic in Canada and the US significantly impacted the myriad relationships that exist amongst human and non-human animals. This article highlights the tolls that the virus and lockdown measures took (and continue to take) on companion animals and the veterinary professionals who care for them. Veterinary medicine scrambled quickly to adapt to new parameters of care using pandemic protocols, radically transforming the amount and quality of care for companion animals, and the work lives of those who provide it. Changes in clinic protocols, patient admissions and discharges, deliveries, shipments, appointment scheduling and duration, and the availability of food, pharmaceuticals and medical equipment all impacted the lives of non-human animals, and the work lives of those providing veterinary care . The authors employed mixed methods research, combining ethnographic data with secondary source data analysis to illuminate the new realities of labor and interspecies care work in the lockdown-induced anthropause. The findings are relevant to veterinary professionals, researchers, companion animal guardians, animal welfare advocates, and possibly emergency management organizations in prepareding for future catastrophic events.