Background: Unwanted teenage pregnancies have a notable detrimental impact on the learners’ trajectory and have been associated with jeopardizing the students’ educational progress and future career prospects. These pregnancies are mostly unplanned and unintended and many are terminated, either legally or illegally. Each year, about 210 million women around the world become pregnant. Among them, about 75 million pregnancies (36%) are unplanned and/or unwanted. Globally, more than 20 million women experience ill health as a result of pregnancy each year. Objective: To assess knowledge, attitude and practice towards emergency contraceptive methods among female students in Unity University, Adama, Oromia, Ethiopia, 2019. Methods: A Cross-sectional quantitative study was conducted among 276 Unity University undergraduate students. Self-administered questionnaire was used to collect the desired sample size. Study participants were selected by stratified random sampling, stratify based on year and department in the study. Data entry was done by using Epi Info and analysis was done by using SPSS version 21. Data was presented by tables, figures, diagrams. Result: The response rate was 100% (n=276), out of which 259 (93.8) where within the age category of 15-24 and 17 (6.2) of them are within the age category of 25-29. 159 (72.4%) of the respondents had good knowledge on Emergency contraceptive (EC). More than half (69.7%) of them had positive attitude towards Emergency contraceptive. Of the Respondents 75 (27.5%) were experienced sexual intercourse out of them 55 (20.4%) were used Emergency contraceptive. Conclusion: overall awareness of EC was very high among female students at the Unity University, more than half had good knowledge of EC and majority of them had a positive attitude towards using EC. Use of EC was low and half of those who were pregnant reported that the pregnancy was unintended.