Emergency Abdominal Surgery Research Articles

Understanding early deaths after major emergency abdominal surgery: An observational study of 754 patients.

Major emergency abdominal surgery is associated with severe postoperative complications and high short- and long-term mortality. Despite recent advancements in standardizing multidisciplinary care bundles, a subgroup of patients continues to face a heightened risk of short-term mortality. This study aimed to identify and describe the high-risk surgical patients and risk factors for short-term postoperative mortality. In this study, we included all patients undergoing major emergency abdominal surgery over 2years and collected data on demographics, intraoperative variables, and short-term outcomes. The primary outcome measure was short-term mortality and secondary outcome measures were pre, intra, and postoperative risk factors for premature death. Multivariable binary regression analysis was performed to determine possible risk factors for short-term mortality. Short-term mortality within 14days of surgery in this cohort of 754 consecutive patients was 8%. Multivariable analysis identified various independent risk factors for short-term mortality throughout different phases of patient care. These factors included advanced age, preoperative history of myocardial infarction or ischemic heart disease, chronic obstructive pulmonary disease, liver cirrhosis, chronic kidney disease, and vascular bowel ischemia or perforation of the stomach or duodenum during the primary surgery. Patients at high risk of early mortality following major emergency abdominal surgery exhibited distinct perioperative risk factors. This study underscores the importance of clinicians identifying and managing these factors in high-risk patients to ensure optimal care.

The importance of predictive markers in incarcerated abdominal wall hernia.

Emergency abdominal wall hernia repairs play a significant role in general surgical emergencies. In such cases, the time taken to decide on surgery is crucial, as the situation may progress to necrosis, perforation, and organ resection due to strangulation following incarceration. To facilitate the early detection of this condition, studies have been conducted on various predictive markers, most of which are related to similar markers used in acute mesenteric ischemia. This study aims to assess the predictive significance of preoperative laboratory and imaging findings in incarcerated abdominal wall hernia with strangulation. Retrospectively, 122 patients who underwent emergency surgery for incarcerated abdominal wall hernias with a preoperative diagnosis between January 1, 2018, and September 1, 2023, at the General Surgery Clinic of Samsun University Education and Research Hospital were included in the study. According to the examination of the operation notes, Group I was designated for patients who underwent bowel resection, Group II for those who underwent omental resection, and Group III for those without resection. The study investigated the association between patients 'age, gender, hernia type and side, preoperative laboratory parameters (pH, Base Excess (BE), Lactate, White Blood Cell Count (WBC), Neutrophil (N), Lymphocyte (L), Monocyte (M), Platelet (P), C-Reactive Protein (CRP), and pH/BE, pH/Lactate, Lactate/BE, N/L, N/M, L/M, N/CRP, M/P, P/CRP ratios), physical examination (PE), and imaging findings among the resection groups. Out of the 122 patients operated with a preliminary diagnosis of acute incarcerated abdominal wall hernia, 68 were female, 34 were male, and the median age was found to be 67.16 (30-99). In the conducted statistical analysis, mean values of Lactate (p = 0.007), WBC (White Blood Cell) (p = 0.001), Neutrophil (p < 0.001), and NLR (Neutrophil-to-Lymphocyte Ratio) (p = 0.003) were significantly different based on resection groups. Subsequent pairwise comparisons indicated that these differences were attributed to variations in mean values of Lactate, WBC, Neutrophil, and NLR between the Bowel Resection and Resectionless groups. Mean values of Monocytes were also significantly different among resection groups (p = 0.049), and pairwise comparisons revealed that this difference was due to variations in mean values of Monocytes between the Omental Resection and Resectionless groups. The cut-off values were determined as follows in the ROC analysis: 1.2 mmol/L for Lactate, 18.5 (10^9/L) for WBC, 8.1 (10^9/L) for Neutrophil and 10mg/L for CRP concerning bowel resection. In cases of abdominal wall hernia operations due to incarceration, bowel and/or intra-abdominal organ resections related to strangulation can lead to significant morbidity and mortality. Beyond the imaging methods available for preoperative assessment, high levels of laboratory parameters, including Lactate, WBC, Neutrophil, and NLR ratio, may primarily indicate the need for bowel resection, considering that omental resection is associated with lower morbidity and mortality compared to bowel resection, elevated levels of monocytes may primarily indicate the requirement for omental resection in emergency abdominal wall hernia surgery. We recommend that this be prioritized in emergency surgery to prevent complications such as bowel perforation and sepsis and improve clinical outcomes. The surgeon is advised to keep this in mind.

Diagnostic accuracy of laparoscopy in non-traumatic emergency abdominal surgery

Introduction: Laparoscopy with high diagnostic accuracy allows for complete and direct visualization of the intraperitoneal viscera, significantly reducing therapeutic errors. The objective of our study was to evaluate the diagnostic accuracy of laparoscopy in the management of non-specific acute abdomen. Material and Methods: Descriptive and prospective, evaluative study conducted between February 2018 and October 2021, focusing on the role of emergency abdominal laparoscopy. Results: Specificity, sensitivity, positive predictive value, and negative predictive value of laparoscopy in our patients were 100%. Intraoperatively, laparoscopy corrected the preoperative diagnosis in 15.73% of cases. It prevented unnecessary laparotomies in 05 cases. Conclusion: Laparoscopy has a very high diagnostic accuracy. It can be safely used in emergency abdominal surgery, as a substitute for laparotomy.

Abdominal emergency laparoscopy: Addressing anesthetic concerns for abdominal emergency surgery

Introduction: CO2 insufflation during laparoscopic procedures leads to respiratory changes, making general anesthesia during laparoscopy considered high-risk anesthesia. In an emergency context, this risk is likely heightened. The objective of our study is to evaluate the role of anesthesia during laparoscopy in non-traumatic emergency abdominal surgery. Materials and Methods: Descriptive and prospective study conducted between February 2018 and October 2021, involving 337 patients undergoing laparoscopic surgery for non-traumatic acute abdominal emergencies. Results: Of the 337 patients operated on, 190 were female (56.4%) and 147 were male (43.6%), with a mean age of 38 years ± 15 years (range 15-82 years). Comorbidities were noted in 109 patients (32.3%), with 39 patients (11.6%) having multiple concomitant comorbidities. Our patients were classified as ASA I in 74.8% (252 patients), ASA II in 22% (74 patients), and ASA III in 3.3% (11 patients). Perioperative morbidity and mortality related to anesthesia were nil. During the analytical study, we found no correlation between anesthesia duration and perioperative and postoperative morbidity and mortality (p value: 0.082) and no relationship between ASA stage and postoperative morbidity (p value = 0.392, chi-square test). Conclusion: Emergency abdominal surgery via laparoscopy is feasible and safe from an anesthetic standpoint.

Should an appendicectomy be performed in the presence of a macroscopically healthy appendix, during laparoscopic exploration?

Introduction: In contrast to the conventional laparotomy approach, the decision to perform an appendicectomy or not in the presence of a macroscopically normal appendix remains contentious during laparoscopic procedures. Our objective is to assess the rate of appendix conservation and conduct a literature review on the management of a macroscopically normal appendix intraoperatively. Materials and Methods: This was a descriptive, prospective, evaluative study involving 337 patients undergoing laparoscopic surgery for non-traumatic acute abdominal emergencies. Results: Of the 337 patients operated on, 190 were females (56.4%), with a mean age of 38 years ± 15 years (range 15 to 82 years). In 7 patients (2.1%), the appendix appeared macroscopically normal intraoperatively, despite preoperative diagnosis favoring acute appendicitis. These 7 patients (6 females and 1 male) all underwent thorough clinical examination and preoperative ultrasound, although CT scans were performed in only 3 patients. Among these 7 patients, 2 had ovarian cyst torsions, 2 had ruptured hemorrhagic ovarian cysts, 1 case was diagnosed as retrocaecal internal hernia, and in 2 patients, no etiology was identified. The appendix was preserved in all 7 cases. All patients received postoperative antibiotic therapy. No postoperative complications or surgical reinterventions were recorded. Conclusion: Our study demonstrates that a macroscopically normal appendix can be left in situ without postoperative complications or need for surgical reintervention.

Is night emergency laparoscopy a high-risk surgery?

Introduction: Although laparoscopy has become the gold standard for many abdominal emergency pathologies, emergency nighttime laparoscopic surgery is considered high-risk for several reasons, particularly due to limited resources in the operating room during nighttime hours. The primary objective of our study is to evaluate the feasibility and safety of nighttime laparoscopy in the management of non-traumatic acute abdomen. Materials and Methods: Descriptive and prospective, evaluative study conducted between February 2018 and October 2021. Our study included 337 patients undergoing laparoscopic surgery for non-traumatic acute abdominal emergencies. Results: Among the 337 patients, we operated on 211 patients (62.6%) outside of regular working hours (between 4:00 PM and 8:00 AM), of which 189 patients (56.10%) were operated on from 4:00 PM to 12:00 AM, and 22 patients (6.2%) from 12:00 AM to 8:00 AM. The mean operative time was 52.09 ± 24.14 minutes. Perioperative difficulties related to the operated pathology were encountered in 21 cases (9.95%). The overall mean hospital stay was 1 day (range: 7 hours - 4 days). We compared nighttime laparoscopy with daytime laparoscopy and found an advantage in favor of nighttime laparoscopy in reducing hospitalization duration (p value 0.003). Conclusion: Nighttime laparoscopy is feasible and safe.

Emergency laparoscopic surgery in pregnancy

Introduction: The decision to proceed with surgical intervention is often difficult in pregnant women, particularly in emergency contexts. Opting for laparoscopic surgery in pregnant women is even more challenging. Concerns during laparoscopic procedures include potential fetal injury, reduced uterine blood flow due to pneumoperitoneum, and fetal acidosis. The objective of our study is to evaluate the feasibility and morbidity-mortality of emergency laparoscopy in pregnant women. Materials and Methods: This is a descriptive and prospective study conducted between February 2018 and October 2021, involving 337 patients who underwent laparoscopic surgery for acute non-traumatic abdominal emergencies. Results: Among the 190 female patients operated on, 18 patients (9.47%) were pregnant: 8 (44.5%) had acute appendicitis, 7 (38.9%) had acute lithiasic cholecystitis, 2 (11.2%) had ovarian cyst torsion, and 1 (5.6%) had an appendiceal abscess. This laparoscopic management was performed across different gestational ages. The mean gestational age of our patients was 15 ± 14 weeks of amenorrhea (minimum 7 weeks, maximum 29 weeks). The mean operative time for the surgical interventions in these pregnant women was 61.2 minutes ± 20.16 minutes. No intraoperative complications or incidents, no conversions, and no abortions were recorded. Conclusion: Laparoscopy can be safely used to manage acute non-traumatic abdominal emergencies during pregnancy.

Time-to-surgery paradigms: wait time and surgical outcomes in critically Ill patients who underwent emergency surgery for gastrointestinal perforation

BackgroundWaiting time for emergency abdominal surgery have been known to be linked to mortality. However, there is no clear consensus on the appropriated timing of surgery for gastrointestinal perforation. We investigated association between wait time and surgical outcomes in emergency abdominal surgery.MethodsThis single-center retrospective cohort study evaluated adult patients who underwent emergency surgery for gastrointestinal perforations between January 2003 and September 2021. Risk-adjusted restricted cubic splines modeled the probability of each mortality according to wait time. The inflection point when mortality began to increase was used to define early and late surgery. Outcomes among propensity-score matched early and late surgical patients were compared using percent absolute risk differences (RDs, with 95% CIs).ResultsMortality rates began to rise after 16 h of waiting. However, early and late surgery groups showed no significant differences in 30-day mortality (11.4% vs. 5.7%), ICU stay duration (4.3 ± 7.5 vs. 4.3 ± 5.2 days), or total hospital stay (17.4 ± 17.0 vs. 24.7 ± 23.4 days). Notably, patients waiting over 16 h had a significantly higher ICU readmission rate (8.6% vs. 31.4%). The APACHE II score was a significant predictor of 30-day mortality.ConclusionsAlthough we were unable to reveal significant differences in mortality in the subgroup analysis, we were able to find an inflection point of 16 h through the RCS curve technique.Trial registrationFormal consent was waived due to the retrospective nature of the study, and ethical approval was obtained from the institutional research committee of our institution (B-2110–714-107) on 6 October 2021.

Associated factors of mortality and morbidity in emergency and elective abdominal surgery: a two-year prospective cohort study at lacor hospital, Uganda

BackgroundThe mortality rate associated with open abdominal surgery is a significant concern for patients and healthcare providers. This is particularly worrisome in Africa due to scarce workforce resources and poor early warning systems for detecting physiological deterioration in patients who develop complications.MethodsThis prospective cohort study aimed to follow patients who underwent emergency or elective abdominal surgery at Lacor Hospital in Uganda. The participants were patients who underwent abdominal surgery at the hospital between April 27th, 2019 and July 07th, 2021. Trained research staff collected data using standardized forms, which included demographic information (age, gender, telephone contact, and location), surgical indications, surgical procedures, preoperative health status, postoperative morbidity and mortality, and length of hospital stay.ResultsThe present study involved 124 patients, mostly male, with an average age of 35 years, who presented with abdominal pain and varying underlying comorbidities. Elective cases constituted 60.2% of the total. The common reasons for emergency and elective surgery were gastroduodenal perforation and cholelithiasis respectively. The complication rate was 17.7%, with surgical site infections being the most frequent. The mortality rate was 7.3%, and several factors such as preoperative hypotension, deranged renal function, postoperative use of vasopressors, and postoperative assisted ventilation were associated with it. Elective and emergency-operated patients showed no significant difference in survival (P-value = 0.41) or length of hospital stay (P-value = 0.17). However, there was a significant difference in morbidity (p < 0.001).ConclusionCholelithiasis and gastroduodenal perforation were key surgical indications, with factors like postoperative ventilation and adrenaline infusion linked to mortality. Emergency surgeries had higher complication rates, particularly surgical site infections, despite similar hospital stay and mortality rates compared to elective surgeries.

Dishomeostatic phenomena in acute pancreatitis of variable severity

Acute pancreatitis remains one of the most dangerous pathologies in the structure of emergency abdominal surgery. This is due to many reasons, including an increase in the frequency of destructive forms of the disease, high mortality, and frequent unfavorable outcomes. The aim of this study was to investigate a number of leading components of homeostasis in patients with acute pancreatitis of varying severity. A retrospective study was conducted on 50 patients with acute pancreatitis of diff erent severity levels who were hospitalized at the Republican Clinical Hospital named after S.V. Katkovа (Saransk, Russia). The patients were divided into groups: the fi rst group (control, n = 30) consisted of patients with mild acute pancreatitis, and the second group (main, n = 20) consisted of patients with severe acute pancreatitis. The study evaluated the endogenous intoxication syndrome, the activity of lipid peroxidation and phospholipase systems, microcirculation status, liver function, and the activity of the coagulation-lytic blood system. The results showed that in the early stages of acute pancreatitis, several pathological processes were observed: the development of endotoxemia syndrome, activation of lipid peroxidation and phospholipase systems, microcirculation disorders, changes in the coagulation and fibrinolytic links of the hemostasis system, and liver function suppression. The severity of these disorders was associated with the severity of the pathology. In cases of mild severity, the changes in the parameters studied were reversible, while in severe cases they were stable and oftenirreversible. The presence of toxemia, oxidative stress, dysmicrocirculation, and hemostatic disorders should be considered as risk factors for disease progression and complications.

Impact of clinical frailty on surgical and non-surgical complications after major emergency abdominal surgery.

Major emergency abdominal surgery is associated with a high risk of morbidity and mortality. Given the ageing and increasingly frail population, understanding the impact of frailty on complication patterns after surgery is crucial. The aim of this study was to evaluate the association between clinical frailty and organ-specific postoperative complications after major emergency abdominal surgery. A prospective cohort study including all patients undergoing major emergency abdominal surgery at Copenhagen University Hospital Herlev, Denmark, from 1 October 2020 to 1 August 2022, was performed. Clinical frailty scale scores were determined for all patients upon admission and patients were then analysed according to clinical frailty scale groups (scores of 1-3, 4-6, or 7-9). Postoperative complications were registered until discharge. A total of 520 patients were identified. Patients with a low clinical frailty scale score (1-3) experienced fewer total complications (120 complications per 100 patients) compared with patients with clinical frailty scale scores of 4-6 (250 complications per 100 patients) and 7-9 (277 complications per 100 patients) (P < 0.001). A high clinical frailty scale score was associated with a high risk of pneumonia (P = 0.009), delirium (P < 0.001), atrial fibrillation (P = 0.020), and infectious complications in general (P < 0.001). Patients with severe frailty (clinical frailty scale score of 7-9) suffered from more surgical complications (P = 0.001) compared with the rest of the cohort. Severe frailty was associated with a high risk of 30-day mortality (33% for patients with a clinical frailty scale score of 7-9 versus 3.6% for patients with a clinical frailty scale score of 1-3, P < 0.001). In a multivariate analysis, an increasing degree of clinical frailty was found to be significantly associated with developing at least one complication. Patients with frailty have a significantly increased risk of postoperative complications after major emergency abdominal surgery, especially atrial fibrillation, delirium, and pneumonia. Likewise, patients with frailty have an increased risk of mortality within 90 days. Thus, frailty is a significant predictor for adverse events after major emergency abdominal surgery and should be considered in all patients undergoing major emergency abdominal surgery.

Perioperative serum lactate as a predictor of post-operative length of hospital stay and in-hospital mortality in patients undergoing major emergency abdominal surgeries

Perioperative serum lactate as a predictor of post-operative length of hospital stay and in-hospital mortality in patients undergoing major emergency abdominal surgeries

The impact of laparoscopic surgery on postoperative pain: A prospective study

Introduction: The reduction of postoperative pain intensity is recognized as one of the major advantages of laparoscopic surgery. However, even though this pain is of low intensity, it is not completely abolished after laparoscopic surgery, and may even be multifactorial in origin. The objective of our study is to evaluate pain after laparoscopic surgery and to highlight the various causes of pain. Materials and Methods: This is a descriptive and prospective study involving 337 patients undergoing laparoscopic surgery for non-traumatic acute abdominal emergencies between February 2018 and October 2021. Pain was assessed using the visual analog scale (VAS). Results: Postoperative pain was present in 335 patients (99.4%) on postoperative day 0 and in 283 patients (83.98%) on postoperative day 1. This pain was of low intensity in the majority of cases (73%, n=246 patients) on postoperative day 0 and (68.5%, n=231 patients) on postoperative day 1. Surgical site pain was present in 134 cases (39.77%), pain related to delayed intestinal transit in 52 cases (15.43%), shoulder pain related to CO2 in 40 cases (11.87%), and a combination of different types of pain was found in 16.7% of patients. Conclusion: Post-laparoscopic surgery pain is multifactorial, of low intensity, and easily managed with first-tier analgesics.

Rationale and study design for an Individualized PeriopeRative Open lung VEntilatory approach in Emergency Abdominal Laparotomy/scopy: study protocol for a prospective international randomized controlled trial

BackgroundPostoperative pulmonary complications (PPC) are the most frequent postoperative complications, with an estimated prevalence in elective surgery ranging from 20% in observational cohort studies to 40% in randomized clinical trials. However, the prevalence of PPCs in patients undergoing emergency abdominal surgery is not well defined. Lung-protective ventilation aims to minimize ventilator-induced lung injury and reduce PPCs. The open lung approach (OLA), which combines recruitment manoeuvres (RM) and positive end-expiratory pressure (PEEP) titration, aims to minimize areas of atelectasis and the development of PPCs; however, there is no conclusive evidence in the literature that OLA can prevent PPCs. The purpose of this study is to compare an individualized perioperative OLA with conventional standardized lung-protective ventilation in patients undergoing emergency abdominal surgery with clinical signs of intraoperative lung collapse. MethodsRandomized international clinical trial to compare an individualized perioperative OLA (RM plus individualized PEEP and individualized postoperative respiratory support) with conventional lung-protective ventilation (standard PEEP of 5 cmH2O and conventional postoperative oxygen therapy) in patients undergoing emergency abdominal surgery with clinical signs of lung collapse. Patients will be randomised to open-label parallel groups. The primary outcome is any severe PPC during the first 7 postoperative days, including: acute respiratory failure, pneumothorax, weaning failure, acute respiratory distress syndrome, and pulmonary infection. The estimated sample size is 732 patients (366 per group). The final sample size will be readjusted during the interim analysis. DiscussionThe Individualized Perioperative Open-lung Ventilatory Strategy in emergency abdominal laparotomy (iPROVE-EAL) is the first multicentre, randomized, controlled trial to investigate whether an individualized perioperative approach prevents PPCs in patients undergoing emergency surgery.

Laparoscopic Appendectomy in the Treatment of Patients with Complicated Acute Appendicitis

Relevance Treatment of complicated forms of acute destructive appendicitis continues to be an urgent problem in emergency abdominal surgery. Aim of study Improving the results of surgical treatment of patients with appendiceal peritonitis with laparoscopic appendectomy.Material and methods A retrospective analysis of the treatment of 150 patients with acute appendicitis complicated by local and diffuse peritonitis aged from 17 to 69 years was carried out. There were 77 (51.3%) women and 73 (48.7%) men. Depending on the treatment tactics used, two groups of patients were divided. In the main group (64 patients), the leading treatment method was laparoscopic appendectomy. In the comparison group (86 patients), traditional approaches were used, including open appendectomy with the McBurney approach in 72 patients (83.7%) and laparotomy for diffuse peritonitis in 14 (16.4%).Results The analysis of the surgical techniques used showed that in the main group, wound postoperative complications developed in 9 patients (14.1%). In the comparison group, postoperative complications developed in 32 patients (37.2%). For local non­limited peritonitis, the total duration of hospitalization after laparoscopic appendectomy performed in 49 patients was 6.7±1.4 days, and 8.6±2.1 days (p&lt;0.05) in 72 patients who underwent open appendectomy. The duration of hospitalization was 8.2±2.7 days in case of diffuse peritonitis after laparoscopic appendectomy, sanitation and drainage of the abdominal cavity (15 cases), and 12.4±1.3 days (p&lt;0.05) in 14 patients after laparotomy, appendectomy, sanitation and drainage of the abdominal cavity, intubation of the small intestine.Conclusion Laparoscopic appendectomy may be the operation of choice for complicated forms of acute appendicitis according to developed indications. It should be performed by a surgeon experienced in endosurgical operations. To increase the efficiency of washing the abdominal cavity in case of diffuse peritonitis, it is recommended to use hardware sanitation. The capabilities of laparoscopic appendectomy make it possible to adequately perform the required amount of surgical treatment, minimize surgical trauma, and significantly reduce the rate of postoperative complications and the duration of hospital treatment compared to open appendectomy.

Surgical Abdominal Emergencies among Patients with Cerebral Palsy: A Case Report and Review Article

Abstract Surgical abdominal emergencies among patients with cerebral palsy (CP) are infrequently reported. The most commonly reported reason for urgent and emergent abdominal surgery among patients with CP is intestinal volvulus. Intestinal volvulus leads to obstruction and vascular compromise, potentially resulting in life-threatening ischemia and necrosis. Volvulus typically presents with abdominal pain and decreased bowel function. When patients are nonverbal and have baseline bowel dysfunction, symptoms of volvulus can be difficult to diagnose. Here, we present a case of an adult female patient with CP who presented with ischemic colitis with perforation and underwent emergency total colectomy and end-ileostomy. Her postoperative course was complicated by two episodes of intestinal volvulus that occurred one and three months after the initial operation. At the second presentation, she had global bowel ischemia due to the volvulus, which led to her death. We have reviewed and summarized the current literature regarding abdominal emergencies among patients with CP.

Acil Abdominal Cerrahi Yapılan COVID-19 Hastalarında Postoperatif Komplikasyonların Öngördürücüleri

Amaç: COVID-19 dünya çapında hızla yayılması ve pandemi haline gelmesi, cerrahi hastalarda postoperatif komplikasyonların insidansında da artışa neden oldu. Acil ameliyata alınan hastalarda COVID-19 pozitifliğinin ameliyat sonrası komplikasyonları etkileyebileceği açıktır. Bu çalışmada acil abdominal cerrahi uygulanan COVID-19 hastalarında postoperatif komplikasyonlar için öngördürücü faktörlerin değerlendirilmesi amaçlanmıştır.&#x0D; Gereç ve Yöntemler: Bu çalışmada acil abdominal cerrahi uygulanan ve perioperatif 72 saat içerisinde COVID-19 Polimeraz Zincir Reaksiyonu (PCR) testi pozitif sonuçlanan 52 hasta retrospektif olarak değerlendirildi.&#x0D; Bulgular: Çalışmaya dahil edilen hastaların medyan yaşı 50.5’di (aralık: 18-83). 30 günlük mortalite oranı %15.4 olarak saptandı. Postoperatif komplikasyon oranı %23.1’di. Postoperatif komplikasyon durumu ile yaş (p=0.003) ve preoperatif hemoglobin değeri (p=0.001) arasında anlamlı bir ilişki saptandı. Yaş ve hemoglobinin birlikte değerlendirilmesinin postoperatif komplikasyonlar için sensivitesinin %91.7, spesifitesinin %87.5 olduğu görüldü (p

Risk Factors of Wound Dehiscence in Abdominal Surgery

Background: Wound dehiscence, a significant postoperative complication characterized by the partial or complete separation of a surgical wound, remains a challenge despite advances in surgical techniques and perioperative care. It is associated with increased morbidity, mortality, prolonged hospital stays, and higher healthcare costs. Understanding the risk factors that predispose patients to wound dehiscence is crucial for improving surgical outcomes. Objective: The aim of this study was to identify the patient-related and surgical factors that contribute to the risk of wound dehiscence in individuals undergoing abdominal surgery, in order to inform strategies for risk reduction and management. Methods: This prospective cohort study was conducted at the General Surgery Department of Hayatabad Medical Complex, Peshawar, Pakistan, from January 2021 to January 2023. A total of 150 patients who underwent elective or emergency abdominal surgery were included. Exclusion criteria encompassed individuals undergoing obstetric or gynecological procedures and those with a prior history of wound infection or dehiscence. Data on demographic characteristics, comorbidities, type of surgery, surgical approach, and postoperative outcomes were collected. Wound dehiscence was the primary outcome, identified clinically and confirmed by surgical review. Statistical analysis involved descriptive statistics, bivariate analyses using chi-square tests, with significance set at p ≤ 0.05. Results: The mean age of the study population was 45.6 ± 12.3 years, with 60% male and 40% female participants. Comorbidities included obesity (30%), diabetes mellitus (23.3%), hypertension (16.7%), cardiovascular disease (13.3%), and smoking (20%). Elective surgeries constituted 66.7% of cases, with gastrointestinal disorders being the most common indication (46.7%). The open surgical approach was utilized in 80% of procedures. Wound dehiscence occurred in 23.4% of patients with obesity, 18.2% with diabetes mellitus, 15.6% who were smokers, 13% with hypertension, and 18.2% of advanced age. Conclusion: The study highlights obesity, diabetes mellitus, smoking, hypertension, and advanced age as significant risk factors for wound dehiscence following abdominal surgery. Addressing these modifiable factors through tailored preoperative assessment and postoperative care is essential for reducing the incidence of wound dehiscence.

Combination of neuromuscular block monitoring and hand grip strength assessment for patients undergoing emergency abdominal surgery

Relevance. The hand grip strength measurement together with neuromuscular block monitoring played an important role during surgery. They both helped in losing less time during surgery and also facilitate the task of the surgeon. The aim of this study was to reduce time on intubation, facilitate the task of the surgeon and to limit post-surgical pain. In rehabilitation, hand grip strength helps in determining further recuperation measures after asurgery. There are three fundamental principles for an anesthesiologist to ensure that the patient after combined endotracheal anesthesia can be extubated, the first one is to ask the patient to move his head forward, the second one is to ask the patient whether the intubation tube is disturbing him in his mouth and the third most important one is to make the patient hold his wrist very firmly. Materials and Methods. Monitoring of muscle relaxant on induction, intra and post-surgery is carried out using aTOF Watch SX in coordination with handgrip strength measurement on 46 patients aged from 18 to 60 years of BMI of 18-30 kg/m² 15min before endotracheal intubation and 15min, 45min and 210min post extubation by using adynamometer “MEGEON 34090” to help us understand whether after extubation muscle strength changes and to what extent. Also, pre-anesthesiology protocol, combined endotracheal protocol, Microsoft excel advanced, monitoring of hemodynamics, ECG, PEEP, PCO2, PO2, respiratory volume using Drager Fabius. Results and Discussion. The results showed that to reach deep muscle relaxation both atracurium benzilate (FKP Kursk Biofabric company, Kursk, Russia) at TOF 0 took 258.5± 83.5 secs and Cisatracurium benzilate (ZAO Obninsk Chemical pharmaceutical company, Obninsk, Russia) at TOF0-252.4±100.1 secs in emergency patients and basically hand grip strength also was lesser as compared to planned cholecystectomy patients. Conclusion. Rehabilitation was necessary for patients undergoing massive abdominal emergency surgeries underlying the fact that on apain scale 10/10 post surgery, further treatments should be implemented to reduce pain, reduce residual neuromuscular block and muscle weakness after extubation at TOF 90-95%.

Laparoscopy for emergency abdominal surgery is associated with reduced physical functional decline in older patients: a cohort study

BackgroundAn increasing number of older patients require emergency abdominal surgery for acute abdomen. They are susceptible to surgical stress and lose their independence in performing daily activities. Laparoscopic surgery is associated with faster recovery, less postoperative pain, and shorter hospital stay. However, few studies have examined the relationship between laparoscopic surgery and physical functional decline. Thus, we aimed to examine the relationship between changes in physical function and the surgical procedure.MethodsIn this was a single-center, retrospective cohort study, we enrolled patients who were aged ≥ 65 years and underwent emergency abdominal surgery for acute abdomen between January 1, 2019, and December 31, 2021. We assessed their activities of daily living using the Barthel Index. Functional decline was defined as a decrease of ≥ 20 points in Barthel Index at 28 days postoperatively, compared with the preoperative value. We evaluated an association between functional decline and surgical procedures among older patients, using multiple logistic regression analysis.ResultsDuring the study period, 852 patients underwent emergency abdominal surgery. Among these, 280 patients were eligible for the analysis. Among them, 94 underwent laparoscopic surgery, while 186 underwent open surgery. Patients who underwent laparoscopic surgery showed a less functional decline at 28 days postoperatively (6 vs. 49, p < 0.001). After adjustments for other covariates, laparoscopic surgery was an independent preventive factor for postoperative functional decline (OR, 0.22; 95% CI, 0.05–0.83; p < 0.05).ConclusionsIn emergency abdominal surgery, laparoscopic surgery reduces postoperative physical functional decline in older patients. Widespread use of laparoscopic surgery can potentially preserve patient quality of life and may be important for the better development of emergency abdominal surgery.