Emergence Of New Activities Research Articles

The contribution of entrepreneurship centers and business incubators to the Ecuadorian entrepreneurial ecosystem

Introduction: Entrepreneurship centers and business incubators play a crucial role in fostering competitiveness, the emergence of new activities, and self-employment, thereby promoting social cohesion within countries. This research aims to identify the main business incubators and entrepreneurship centers in Ecuador and to assess their key contributions to the entrepreneurial ecosystem. Methodology: This study adopts a qualitative research approach, employing an exploratory-descriptive methodology. Through the collection of data from secondary sources, the study identifies Ecuadorian business incubators, their affiliations with public and private organizations, their primary activities, impacts, and capacities. Results: Nationwide, 28 entrepreneurship centers, both public and private, were identified. The majority are dedicated to guiding entrepreneurs in developing their business models, whether in the initial stages or during expansion, through advisory services, training in various fields, and even financing. Conclusions: While there is evident close collaboration between academia and the private sector, current efforts prioritize promoting the entrepreneurial spirit over the practical implementation of ideas, project capitalization, or addressing specific industrial or social challenges. Therefore, it is necessary to balance these efforts to ensure that entrepreneurial initiatives are not only encouraged but also realized and generate a tangible impact.

Innovation versus novelty in microbial systems.

Innovation versus novelty in microbial systems.

Research of infrastructure of investment and construction process

The article considers the most important factors that led to the emergence of new activities that ensure the creation of high quality consumer value of construction projects, for financing, design, construction and management of which requires expert intervention. The study of investment and construction activities suggests that a group of professionals – functional participants – "promotes the investment process", and this, in turn, allows, according to the author, to distinguish them and combine them with the concept of infrastructure of investment and construction process. Much attention in the article is paid to the study of the essence of the concept of infrastructure as a set of institutions, organizations, government and commercial enterprises that ensure optimal functioning of the process, interaction and effective cooperation of its participants. In the context of the investment and construction process, as an independent subsystem, infrastructure is a set of organizational and legal forms that mediate the movement of the construction project to implementation, or a set of institutions, systems, enterprises serving the process and performing certain functions to ensure effective operation. The infrastructure of the investment and construction process is created by its functional participants, whose activities are commercial in nature and related to the organization of the investment process, increase investment efficiency, reduce costs of institutional investors, solve the problem of optimizing all resources. Therefore, the article considers and analyzes the development, consulting, engineering, auditing, acquiring activities, the emergence of which in the investment and construction process determined the demand for quality real estate, to finance, design, build and manage which requires expert intervention. It is noted that the emergence and development of infrastructure for investment and construction activities. focused on project management and implementation – ie coordination of all actions of the participants, reflects the process of intensive internal restructuring of the construction industry in order to improve economic conditions.

PENGARUH REVITALISASI TERHADAP POLA RUANG KOTA LAMA SEMARANG

The revitalization of the Old City of Semarang has had a significant impact on the physical condition of the area. Initially, the image of the Old City of Semarang as a historical tourist destination is an ancient area with poorly maintained conditions, experiencing flooding every year, and socio-economic problems. Revitalization is one of the efforts undertaken by the government to revive the Kota Lama Semarang area which is experiencing environmental degradation or degradation. Improvement of infrastructure conditions, widening pedestrian paths, and procurement of street furniture are the main focus of the revitalization program. The purpose of this study is to analyze the effect of revitalization on changes in spatial patterns that occur in the Kota Lama Semarang area. In order to achieve these objectives, research objectives are set, namely the identification of the revitalization process, analysis of changes in spatial patterns, and analysis of the impact of revitalization on changes in regional spatial patterns in the Old City of Semarang. In this study using quantitative methods through temporal spatial analysis, descriptive analysis and comparative descriptive analysis which aims to determine the relationship between the revitalization process and changes in spatial patterns in the Kota Lama Semarang area. The results showed that revitalization affects the changes in the spatial pattern of the Kota Lama Semarang in terms of spatial use, building characteristics, accessibility, land prices and settlement characteristics. Many things have happened due to revitalization, such as the emergence of new activities in the form of commercial areas, trade areas and changes in community activities in the Kota Lama Semarang area. Spatial use control is carried out to control changes in spatial patterns that occur so that it remains in accordance with the designation of the area of the Old City of Semarang

Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications

The tautomerase superfamily (TSF) is a collection of enzymes and proteins that share a simple β-α-β structural scaffold. Most members are constructed from a single-core β-α-β motif or two consecutively fused β-α-β motifs in which the N-terminal proline (Pro-1) plays a key and unusual role as a catalytic residue. The cumulative evidence suggests that a gene fusion event took place in the evolution of the TSF followed by duplication (of the newly fused gene) to result in the diversification of activity that is seen today. Analysis of the sequence similarity network (SSN) for the TSF identified several linking proteins ("linkers") whose similarity links subgroups of these contemporary proteins that might hold clues about structure-function relationship changes accompanying the emergence of new activities. A previously uncharacterized pair of linkers (designated N1 and N2) was identified in the SSN that connected the 4-oxalocrotonate tautomerase (4-OT) and cis-3-chloroacrylic acid dehalogenase (cis-CaaD) subgroups. N1, in the cis-CaaD subgroup, has the full complement of active site residues for cis-CaaD activity, whereas N2, in the 4-OT subgroup, lacks a key arginine (Arg-39) for canonical 4-OT activity. Kinetic characterization and nuclear magnetic resonance analysis show that N1 has activities observed for other characterized members of the cis-CaaD subgroup with varying degrees of efficiencies. N2 is a modest 4-OT but shows enhanced hydratase activity using allene and acetylene compounds, which might be due to the presence of Arg-8 along with Arg-11. Crystallographic analysis provides a structural context for these observations.

Spatial development planning in peri-urban space of Burdwan City, West Bengal, India: statutory infrastructure as mediating factors

Population growth, economic development, and rural–urban migration have contributed to the rapid growth of peripheral areas in Indian cities. The immigration of population and emergence of new activities are changing these areas, as seen in changes in land use and occupational structures, reduced agricultural activities, and built-up structural development. The city of Burdwan is no exception to this phenomenon of accelerated population growth. With the passage of time, this city is expanding towards peri-urban villages, thereby strongly influencing the peripheral rural settlements in the dimensions of both natural and social resource. Thus, advance spatial development planning of land use and infrastructure for a speedily growing population that is projected is highly important. In the current decade, the use of an environmental approach in the planning of peri-urban areas has gained significant recognition. However, desegregation of socio-economic sectors has been mentioned very loosely. This paper seeks to achieve spatial development in peri-urban areas by taking into account socio-economic and demographic factors along with environmental principles. Hence, the objective for the study is based on a mixed-method approach to assess major problems of a peri-urban space. We applied an interdisciplinary approach which merged household survey and temporal change analysis over three time periods (1991, 2001, and 2011) based on geographical information systems. Results show substantial built-up growth and that agricultural workers drastically decreased in the last twenty years. Finally, considering the structural and functional potential of peri-urban areas, land use zoning plan was prepared. Further, zone-wise development plan was designed for sustainable and intensive development of the city. This study has explicitly focused on quantifying physical and social infrastructure at various spatial scales, which can be implemented in other cities for balanced regional development and in identifying and mitigating disparities for balanced regional development.

Есть ли шанс возродить французскую промышленность?

Deindustrialization in advanced economies has become one of the consequences of economic globalization. This process has been developing over the past four decades, however, the destruction of industrial potential has been seriously discussed recently. The article analyzes the process of France’s entry into the global economy and the subsequent partial destruction of the national industry. The French model of entry into the open economy was distinguished by its own characteristics: the speed and scale of the transformation, accompanied by rising unemployment and curbing income inequality. French society was not ready for globalization and perceived it as a threat. Deindustrialization, which took place against the background of structural and technological restructuring of production, changed the social structure. The first social victims were workers. In contrast to a reduction in the number of workers in France, the representation of top and middle managers increased. At the same time, fragmentation of the middle class took place; its lower strata were threatened by unemployment and lumpenization. In French society, new social divisions appeared, and socio-spatial imbalances grew. At the end of the global financial and economic crisis of 2008–2009, the European countries recalled the industrial policy. France is currently endorsing a new program for development of an innovative economy. In the case of its implementation or non-implementation, three scenarios are possible. The “Step into the Future” scenario involves the implementation of a program for development of an innovative economy and modernization of society. New industries will create new jobs, contribute to the emergence of new activities and new professions related to the assimilation and processing of information. The “French Desert” is possible if the first scenario cannot be implemented. The “Back to Etatism!” scenario implies a technocratic version of modernization and strengthening state influence on society.

Analysis of ICT education in Azerbaijan: current state, foreign experience, problems and prospects

Purpose of the study. The aim of the study is to develop recommendations for improving educational curricula for ICT specialties taught to students in universities of the Azerbaijan Republic.The urgency of the problems outlined in this article is determined by the urgency of the transition to the modernization of the national education system and its integration into the global and world educational space, the requirements of creating an information society in Azerbaijan.Modern society needs qualified personnel who own new information technologies and are able to apply them in various fields of activity. Therefore, the process of modernization of the ICT education system is necessary; curricula should comply with international standards and specialization profile.Materials and research methods. The article provides a comparative analysis of higher professional ICT education in the developed countries of the world, shows the similarities and differences of the educational systems of the United States, European countries, Russia and Azerbaijan, analyzes the trends and features of the educational systems of developed countries, provides a list of IT specialties in demand today and in the near future. . The article also outlines the problems facing higher education institutions that train IT profile specialists.As research materials are used:policy documents of the governing bodies of the Republic of Azerbaijan in the field of higher vocational education;training programs of ICT specialties of universities of the Azerbaijan Republic;study programs of ICT specialties of leading foreign universities;scientific works of domestic and foreign authors in the field of ICT education;recommendations of international organizations ACM (The Association for Computing Machinery) and IEEE (The Institute of Electrical and Electronics Engineers) on the development of curricula for various areas of IT profile.Results. Taking into account the analysis of the curriculum of the IT profile of foreign universities, recommendations of international organizations of standardization, monitoring of the labor market, methodical recommendations were developed to improve ICT education in Azerbaijan. The necessity of modernization of the education system and bringing it into line with modern requirements is shown.Conclusion. In modern conditions of the formation of the information society in Azerbaijan, the educational program of the university should take into account the results of monitoring the labor market and the dynamics of macroeconomic changes, the disappearance of old and the emergence of new activities related to the use of ICT. Therefore, an important task is to prepare highly professional specialists in the country who are able to use and implement the advanced development of information technologies in practice.The recommendations outlined in the article can be used by university professors to improve the educational programs of ICT specialties in Azerbaijan.

Evaluating the efficiency of higher education institutions in Tunisia

Due to the increase in students' number and the emergence of new activities, the efficiency of higher education institutions (HEIs) in Tunisia is receiving increasing attention in the academic as well as in the public discourse. In this paper, data envelopment analysis (DEA) was used to analyse the relative efficiency of 62 Tunisian HEIs for the academic year 2010-2011. The total number of HEIs was divided into two subsets - experimental group composed of 30 institutions and non-experimental group containing 32 - in order to minimise heterogeneity in the sample. The findings show that the technical and scale efficiency in the HEIs sample appear to be high on average. There were also small slacks in input utilisation. Also, more HEIs were operating at decreasing returns to scale, indicating a potential to downsize. DEA identifies the reference groups for inefficient institutions and indicates the direction of desirable productivity improvements. As such, the results obtained by DEA can serve as a benchmarking instrument for the leaders of the university system and contribute in more efficient allocation of scarce resources. Policy makers could distribute a share of budget according to institution performance and creating an atmosphere of competition in the Tunisian higher education system.

ВЛИЯНИЕ ИНФОРМАЦИОННО-КОММУНИКАЦИОННОГО СЕКТОРА НА ПРОИЗВОДИТЕЛЬНОСТЬ ТРУДА В ЭКОНОМИКЕ РФ

The widespread introduction of information and communication technologies (ICT) is an immanent factor of labor productivity enhancement not only in the ICT sector, but also in related and traditional industries, contributing to the emergence of new activities. The authors analyzed the factors that are important for the growth of labor productivity, both in the ICT sector, and from the position of the impact of functional results of the sector on the growth of labor productivity in the Russian economy. Methodological platform of the analysis is considered to be the concept of duality of effects created by the ICT sector: the presence of direct effects (localized directly in the sector) and the effects induced on labor productivity of the economy as a whole. The role of the sector as a generator of development of other industries related and unrelated with a process link to the ICT sector is shown, which allows to determine the most important factors of economic development, to position the Russian Federation in the global process of technological changes.

Evaluating the efficiency of higher education institutions in Tunisia

Due to the increase in students' number and the emergence of new activities, the efficiency of higher education institutions (HEIs) in Tunisia is receiving increasing attention in the academic as well as in the public discourse. In this paper, data envelopment analysis (DEA) was used to analyse the relative efficiency of 62 Tunisian HEIs for the academic year 2010-2011. The total number of HEIs was divided into two subsets - experimental group composed of 30 institutions and non-experimental group containing 32 - in order to minimise heterogeneity in the sample. The findings show that the technical and scale efficiency in the HEIs sample appear to be high on average. There were also small slacks in input utilisation. Also, more HEIs were operating at decreasing returns to scale, indicating a potential to downsize. DEA identifies the reference groups for inefficient institutions and indicates the direction of desirable productivity improvements. As such, the results obtained by DEA can serve as a benchmarking instrument for the leaders of the university system and contribute in more efficient allocation of scarce resources. Policy makers could distribute a share of budget according to institution performance and creating an atmosphere of competition in the Tunisian higher education system.

Computer prediction of biological activity of 2-methyl(phenyl)-6,9-epoksybenzo[g]quinoline-4,5,10-Trion and 5-methyl-(1,2,4-triazolo[4,3-a] quinoline)

One of the priority measures, which are evaluated in the creation of new effective medicines, is their high selective effect and lack of side effects. A considerable interest is the possibility of combining several structures of heterocycles in one molecule, such as quinoline and furan, which may cause an increase in biological activity of these combined compounds or an emergence of new properties. It is known that derivatives of 1,2,4-triazolo[4,3-a]quinoline have anticonvulsant effect and treat the syndrome of disorders with the nervous system.The aim of research. The main purpose of this work was an establishment of combinatorial library of bioregulators, which combines structures 5,8-dioksoquinoline and furan (1-8), quinoline and triazole (9-12), using computer program PASS (Prediction Activitity Spectra for Substances). Virtual screening of heterocycles derivatives was conducted to determine the direction of their bioactivity researches.Materials and methods. The virtual screening of compounds was performed by using the computer program PASS (Prediction Activity Spectra for Substances). For the specific activity the increase of Pa quantity and the decrease of the Pi quantity, helps to get the greater chance to detect this activity in the experiment.Predicting the probability of substance manifestation of specific types of biological activity determines which tests are the most appropriate for studying the biological activity of specific chemical substances and which substances of those that are available to the researcher likely will show the desired effect. With theoretical prediction the most likely basic structures of new compounds with desired biological effect, which best suits the task will be selected.Results. Analysis of computer prediction demonstrates the promising search of antineoplastic, antibiotic, analgesic and other types of activity in some of these compounds. An important instant of prediction of these substances is their lack of high toxicity terato-, kantsero-, embryo- and mutagenicity.The computer prediction of derivatives of triazole[4,3-a]quinolone had shown that the substitution of hydrogen on the carboxylic acid residue decreases the expected activity, but significantly expands its range and appears new types of biological activity. Injecting the propionic acid residue, you can observe an antieczematic activity, but injecting propylene - antiviral and antiinflammatory activities. Amidation of carboxylic acids leads to a decrease in the activity of structure-leader and the emergence of new activities, such as antineurotic, antinociceptive and muscle relaxant.Conclusion. Data of the computer prediction shows us the promising search of the following two directions of bioregulators that can exhibit antineoplastic, antiradical, analgesic, antiinflammatory, diuretic and other biological activities.

Movilización y modernidad en el Medio Oriente

Las movilizaciones actuales en el Medio Oriente están ancladas en las transformaciones que resultaron de la participación de la región en la construcción de una modernidad global institucional, productiva e ideológica. En este artículo se explora el surgimiento de nuevos actores sociales en la región y los movimientos sociales que han propiciado, proponiendo o resistiendo reformas al Estado y al orden público desde las últimas décadas del momento otomano, durante el periodo de los mandatos y más allá del pacto social poscolonial. La modernidad otomana se caracterizó por intensos debates y el surgimiento de nuevas actividades y espacios públicos, que permitieron la movilización de actores nuevos y establecidos; debates que fueron suspendidos, por la fuerza, por las administraciones mandatarias y sus colaboradores. El proceso de descolonización, a mediados del siglo xx, y la ola de revoluciones que se desencadenó, llevaron al poder en gran parte de la región a sectores históricamente marginales. Ellos, a su vez, institucionalizaron sus propias visiones del bien común, e instauraron un pacto social poscolonial que defendía la construcción de aparatos de Estado autoritarios y militarizados. Se hace un repaso crítico de las formas que ha tomado la movilización en la región en las últimas décadas: el paisaje social y las dinámicas de organización que han dado pie a las revueltas y las revoluciones que observamos hoy día. Finalmente, se presenta una discusión de la cobertura mediática de los levantamientos en la prensa árabe e internacional en línea, y se señalan sinergias y discontinuidades, evidenciadas en la interpretación de la participación de las mujeres en las revueltas y la presencia islamista en los procesos de consolidación posrevolucionaria.

High frequency oscillations in the somatosensory evoked potentials (SSEP's) are mainly due to phase-resetting phenomena

A small series of high frequency oscillations (HFOs) overlapping the earliest part of the N20 wave can be observed in the somatosensory evoked potentials (SSEPs) of normal subjects. We tried to elucidate whether these high frequency components are mainly due to phase-resetting phenomena, to the emergence of new oscillations related to the stimuli, or to a combination of both. Averaged median-nerve SSEPs from seven healthy subjects were studied by means of time–frequency analysis. The presence of new oscillatory activities was evaluated by averaging the energy of the single-trial time–frequency transforms in the HFOs range (400–1000 Hz). To study phase-resetting phenomena, we measured inter-trial coherence (ITC) in the same frequency range. A marked inter-trial coherence related to the HFOs was found, whereas energy changes (related to the emergence of new oscillations) were minimal. The combination of these three different approaches suggests that the HFOs are mainly due to resettings of the ongoing EEG activity originated in response to the stimuli. The emergence of new activities does not seem to be a relevant mechanism in the formation of these components.

Logiques d'une mise en valeur. L'estran de la baie du Mont-Saint-Michel

The Mentality Underlying Development : The Foreshore of the Mont-Saint-Michel Bay From being a natural site for shellfishery since ancient times, the foreshore of the Mont-Saint-Michel Bay became a productive and cultural center as of the 19th century. From being a natural resource, shellfish became a grown product. This change, which corresponded to the emergence of new activities on the national level, upset the symbolic bonds between men and places of production. Developing this bay, which belongs to the maritime public domain, fits into a productivistic mentality that makes objects and activities, past and present, patrimonial.

Biotechnologies, bioindustries et IAA

Biotechnologies are transversal technologies with high scientific content. Their development promotes the emergence of new activities , the «bioindustries», which conceive and produce production goods and services. This greatly explains the strategies of firms concerned with biotechnologies. Moreover ; some barriers to entry are resulting from specific bioindustries conditions of production. In this regard, the technical and economic capacities of food industries firms may limit their access to this kind of activities.