ABSTRACT Power amplifiers (PA) are used to boost the power of signals. Recently, harmonically tuned power amplifiers (HTPA) offer high efficiency and wider bandwidth than conventional PA. HTPA achieves by shaping waveforms using varying drain terminal impedance conditions (open and short-circuited etc.), but this impedance creates reflected waves at the drain. Existing HTPA methods lack a foundation in Electromagnetic Theory (EM), leading them to miss reflected waves. As a result, the existing equations show problems Type I: generate unwanted and non-required higher-order harmonics (n > 3); and Type II: they cannot link with simulated/measured results properly. This paper proposes an alternative approach by applying EM theory to develop a general HTPA equation. This equation works for any HTPA class and overcomes problems (Type I & II). To validate the proposed theory and equation, continuous mode Class F PA is designed and fabricated. Theoretical, simulation and experimental results all showed good agreement.