Elixir Of Life Research Articles

An elixir of life? Emotional labour in cultural journalism

Recent technological and institutional changes in journalism are believed to have dragged cultural journalism into a crisis. This article looks closely at one thing that makes the job of cultural journalists, in particular critics, distinct from other journalistic beats – the openly acknowledged importance of emotionality and subjectivity in these media workers’ professional practices – and explores the role of emotions in dealing with the crisis in the profession. Based on 14 semi-structured interviews with film and food critics, this article addresses the following questions: What emotional labour do the cultural critics perform? How does professional cultural criticism legitimize itself in the digital era? I suggest that both the film and food critics cherish the fact that their work processes draw heavily on their subjectivity: emotional experiences, political opinions and personal memories. However, to be able do their job, the critics cannot allow such elements of subjectivity to take the reins, and therefore, they perform emotional labour for the successful objectivization of their emotionality: making use of their emotions to better recognize what moments or aspects are significant for the assessment of the quality of the cultural object being reviewed. Furthermore, I suggest that in the context where digitalization has threatened the exceptional position of the professional cultural critic, emotional labour together with some other strategies of handling one’s subjectivity can help them to construct boundaries of professional cultural criticism and thus to reclaim professional legitimacy.

Ganoderma: The wild mushroom with wonderful health benefits

Mushrooms are used as a nutritional rich food and used as traditional medicine to cure many life-threatening diseases since long ago. It is regarded as “Food of gods” by the Romans and a “wonder herb for the warriors” by the Greek and an “elixir of life by the Chinese”. Among all major mushrooms, Ganoderma lucidum is the utmost important one with various therapeutic and pharmaceutical properties. The mycelium, spores and the fruiting bodies carry the medicinal properties. It is more popular in Asian countries but the amazing attributes have widespread throughout the world. It is the new focus of interest in modern pharmacological and biochemical research in recent years. The antimicrobial, anti-diabetic, anti-aging, antioxidant, anti-allergic, anti-inflammatory, immunomodulating functions of mushroom made it more popular among the drug industries. The existence of potential bioactive compounds such as polysaccharides, triterpenoids, proteins, peptides etc have amazing health benefits against hepatitis, hypertensions, asthma, gastric, insomnia etc. Ganoderma lucidum is proved as one of the best anti-cancer agents from decades due to its inhibitory effect on cancerous and tumour cells, protects from cell proliferation etc. This review describes about all the amazing health benefits of G. lucidum. But more research is required in near future to discover novel bioactive compounds and mass production of this medicine which will help the mankind.

嫦娥 (The Butterfly Lovers), and: 嫦娥 (The Moon Lady)

嫦娥 (The Butterfly Lovers), and: 嫦娥 (The Moon Lady) Diana Cao (bio) 嫦娥 (The Butterfly Lovers) they spent the summer spinning silk buttons fastened in air. he found her humming to swaying leaves. a current across persuasions blew until the world quaked,and split form— and the bodies at stake, the interior paramour, the pupae inside the chrysalides, evolved, became exterior: extended wings studded with the Pleiades. a pulse quickens before it slows. from one death in the dark, they eclose. [End Page 48] 嫦娥 (The Moon Lady) My shadow stains the moon. Will I return to Earth?Everything looks brighter here, but not as clear. Everything looks brighter here, but not as clear:A million compromises crowd our Earth. I’ve made a million compromises since birth:When I was a girl, I was the last to eat. I was still just a girl—I longed to eatTreats baked at dawn with egg yolk, lotus, red bean, Your mooncakes split at dusk with lotus filling.The elixir of life wasn’t nearly so sweet. The elixir of life went quickly, my sweet—I betrayed you, drank it all, I drank it all down. My betrayalStains the moon. Will I return to Earth? [End Page 49] Diana Cao diana cao is a data analyst and JD candidate at Harvard Law School. She has received scholarships from Summer Literary Seminars and the Bread Loaf Writers’ Conference, and was a poetry finalist in Matrix Magazine’s LitPOP contest. Her work is forthcoming in Gulf Coast and Crazyhorse. * Copyright © 2021 University of North Carolina Wilmington

Harnessing Technologies for Mitigating the Water Woes in the City of Bengaluru

Industrialization has caused most of the world's environmental problems like climate change, water security issues, biodiversity issues among others. Water-related issues like water scarcity, lack of water quality, water sanitation issues, lack of proper water resources management are some of them. Urbanization, population increase, pollution has led to an increase in water demand. Water being the elixir of life, is essential for the day-to-day living of an individual. The Fourth Industrial Revolution technologies like AI, IoT, Blockchain, Machine Learning have the capability of bringing solutions to these issues. The current study focuses on the water woes of Bengaluru, a fast-growing urban city, due to its migrating population. The woes are also due to the irresponsible behaviour of builders converting lakes into real estate infrastructure leading to clogged drains, excess sewage creation and flooding. A huge mismatch between demand and supply of water is created due to these issues. Before the city hits the Day Zero – no water day, it is significant to set up water infrastructure along with technology implementation which will help resolve this burning issue at the earliest.

“Elixir of life:” Palliative care

“Elixir of life:” Palliative care

Water for Health: An overview of principles and practices of Water consumption in Ayurveda

Water is the most essential element of human life next to air. Ayurveda considers water as the elixir of life. Modern day lifestyle undermines the importance of water with various inappropriate practices prevailing among individuals. People are confronted with a flood of advice regarding drinking of water. Present day research data indicating effect of water consumption on health is very minimal & basic. Ayurveda has elucidated in detail about the principles of water consumption for maintenance of Health, Prevention of illness and alleviation of disease. At the moment resurfacing of such Ayurvedic principles are very important. In this study, Ayurveda Classics were reviewed in terms of various aspects of water viz. importance of water, relation of water intake to food, water consumption according to season, therapeutic uses of water and indications-contraindications of water. The electronic databases Google Scholar and PubMed were searched for relevant contemporary literature. Classical Ayurveda methods of water purification can be economical, green and environment friendly. Ayurveda advocates the optimal & judicious use of water for the maintenance of health. Due to the ritu (season) specific state of dosha, specific water is indicated in different season. Medicated water, administered as per the disease condition, helps in balancing the vitiated doshas. This review has attempted to compile and analyse the significance of water in maintenance of health and alleviation of disease of an individual. Scope: This exploratory work may be considered as a potential source for generating newer hypothesis in the field of ‘Water and Health research’.

Comparative Review on Pharmacognostical and Pharmacological activities of Ocimum Species

Tulsi, also known as holy basil, is indigenous to the Indian continent and highly revered for its medicinal uses within the Ayurvedic and Siddha medical systems. In the Ayurveda system tulsi is often referred to as an “Elixir of Life” for its healing powers and has been known to treat many different common health conditions. In the Indian Materia Medica tulsi leaf extracts are described for treatment of bronchitis, rheumatism, and pyrexia. Bioactive compounds of Tulsi responsible for its various medicinal properties and their effects at the molecular level need to be investigated in more detail for pharmaceutical therapeutic applications. Reported therapeutic uses include treatment of epilepsy, asthma or dyspnea, hiccups, cough, skin and haematological diseases, parasitic infections, neuralgia, headache, wounds, and inflammation and oral condition. The juice of the leaves has been applied as a drop for ear ache, while the tea infusion has been used for treatment of gastric and hepatic disorders. The roots and stems were also traditionally used to treat mosquito and snake bites and for malaria. The present review summarizes the comprehensive information regarding Pharmacognostical and Pharmacological activities of different varieties of tulsi.

Harnessing technology for mitigating water woes in the city of Bengaluru

Industrialization has caused most of the world’s environmental problems like climate change, water security issues, biodiversity issues among others. Water-related issues like water scarcity, lack of water quality, water sanitation issues, lack of proper water resources management are some of them. Urbanization, population increase, pollution has led to an increase in water demand. Water being the elixir of life, is essential for the day-to-day living of an individual. The Fourth Industrial Revolution technologies like AI, IoT, Blockchain, Machine Learning have the capability of bringing solutions to these issues. The current study focuses on the water woes of Bengaluru, a fast-growing urban city, due to its migrating population. The woes are also due to the irresponsible behaviour of builders converting lakes into real estate infrastructure leading to clogged drains, excess sewage creation and flooding. A huge mismatch between demand and supply of water is created due to these issues. Before the city hits the Day Zero – no water day, it is significant to set up water infrastructure along with technology implementation which will help resolve this burning issue at the earliest.

Analysis and Optimization of Groundwater Distribution Using SVM and Neural Networks

Water is the elixir of life. Gradual increase in demand for water, whether for agricultural, personal or industrial use has led to the depletion of clean water resources. Hence, to battle this water crisis, we propose to build a model using machine learning. The goal of the model is to predict the groundwater levels of different areas in Delhi with respect to various parameters that affect the groundwater levels in the environment. To find the best machine learning technique to perform the prediction of groundwater, we initially perform a comparative analysis of four machine learning techniques: Support vector machine, Artificial neural networks, Random forests and Linear regression models. We proceed with the models that give satisfactory results. We perform forecasting using the ARIMA model to predict the parameters that affect groundwater levels across the next ten years. The forecasting of parameters resulted in increasing the database by two times, hence we performed the prediction of the water table using the models Support vector machine, Artificial neural networks and Linear regression models. Thus, concluded that the Artificial neural networks model performs better than the Support vector machine and Linear regression models. It presented with a mean absolute error of 85.26 as opposed to linear regression model that presented with a mean absolute error of 94.95 and Support vector machine with a mean absolute error of 127.74. Further these predictions are used to build optimized groundwater distribution routes using the optimization algorithm vehicle routing problem. If these routes are implemented using proper infrastructure, we can provide the resource of groundwater to the areas that are experiencing scarcity of water.

A Systematic Review on Neuro-Psychopharmacological effects of Celastrus paniculatus (Malkangani) Oil

Herbal drugs are conventionally employed to treat various human ailments. Mental and nervous disorders are the serious public health challenge globally, particularly in developing countries. Psychotherapy does not meet proper therapeutic possibilities for most of the patients with neurological and psychological disorders but natural remedies are ultimate relief and therapeutic hope for such patients. Many synthetic medications for nervous disorders although helpful lead to poor patient compliance because of many unpleasant but unavoidable side effects. Therefore herbal therapy is being preferred over modern medical treatments. Much contemplation and so scope is drawn towards herbal panacea of many mental disorders. This session deals with a herbal drug, Malkangani whose seeds and seed oil are being used traditionally as a therapeutic regimen for various nervous disorders like anxiety, depression and as neuroprotective agent and memory enhancer. This topic also discusses about the pharmacognostic characters, phytochemistry and neuro-psychopharmacological effects of Malkangani oil. Malkangani oil or Jyothishmati oil obtained from Celastrus paniculatus, mentioned in Ayurveda as Tree of Life or Elixir of Life is one such drug which has been extensively used to treat various central nervous system disorders. The current review is an endeavor to summarize the information based on the utility of malkangani oil to treat various neurological and psychological disorders. Malkangani oil obtained from the dried seeds of Celastrus paniculatus belonging to Celastraceae family possess neuromodulating, anti-oxidant and neuroprotective, sedative, tranquilizing effect, anti-convulsant, anti-amnesic effect, anti-aging, antianxiety, antidepressant, learning and memory enhancing, nootropic, anti-nociceptive and anti-inflammatory effects. The studies on various laboratory animals like mice, rats, rabbits, monkeys revealed the excellent effects of malkangani oil on the brain. Malkangani oil contain sesquiterpene alkaloids, evoninoate sesquiterpene alkaloids, polyalcohols and fatty acids as the major phytoconstituents including some mineral elements. The exact constituent responsible for CNS effects of malkangani oil is not yet found which can be explored in future researches.

Wired Sensor Systems for Water Quality Monitoring

Water is an essential need and elixir of life. People all the world are fighting for their drinking water in order to keep it clean. No matter in what form it is rivers, lakes etc people have taken extreme measures to keep their water drinkable and useable for both humans and animals. Water is a significant characteristic asset without which no life can be envisioned. In any case, individuals misuse this real asset and cause wastage of water. We provide energy saving solution for monitoring the water quality. The proposed idea will build an IOT based sensor which monitors the pH, temperature, conductivity, dissolved oxygen, turbidity, bacteria, etc. present in the water collected. The sensors collect data and send it through a network. Then server will upload the data to the cloud. The remote water station will read the collected data and determine the quality of water. Henceforth, this application can be used on bigger scales, saves time and man-power.

A Chalcone from Ashitaba (Angelica keiskei) Stimulates Myoblast Differentiation and Inhibits Dexamethasone-Induced Muscle Atrophy.

Ashitaba, Angelica keiskei Koidzumi (AK), as a traditional medicine in Korea, Japan, and China, has been known as an elixir of life having therapeutic potential. However, there is no scientific evidence to support that Ashitaba can enhance or maintain muscle strength. To find a new therapeutic agent from the medicinal plant, we evaluated the anti-myopathy effect of chalcones from ethanol extract of AK (EAK) in cellular and animal models of muscle atrophy. To examine anti-myopathy activity, EAK was treated into dexamethasone injected rats and muscle thickness and histopathological images were analyzed. Oral administration of EAK (250 or 500 mg/kg) alleviated muscle atrophic damages and down-regulated the mRNA levels of muscle-specific ubiquitin-E3 ligases. Among ten compounds isolated from EAK, 4-hydroxyderricin was the most effective principle in stimulating myogenesis of C2C12 myoblasts via activation of p38 mitogen-activated protein kinase (MAPK). In three cellular muscle atrophy models with C2C12 myoblasts damaged by dexamethasone or cancer cell-conditioned medium, 4-hydroxyderricin protected the myosin heavy chain (MHC) degradation through suppressing expressions of MAFbx, MuRF-1 and myostatin. These results suggest that the ethanol extract and its active principle, 4-hydroxyderricin from AK, can overcome the muscle atrophy through double mechanisms of decreasing muscle protein degradation and activating myoblast differentiation.

Evaluate the Irrigation Water Quality in Salem District, Tamil Nadu, India

Water is one in all the foremost indispensable renewable assets and is that the elixir of life. In this present world population is increasing tremendously. Rate of technological development in industry and agriculture is also high. The mentioned top of the reason has enlarged the demand for water which is going to be a major crisis in next to the upcoming future. Quality of groundwater was assessed by collecting sixty-six sampling spots in January 2017(Post monsoon) and May 2017(pre monsoon) Irrigation water quality interpretation was done by using Sodium Adsorption Ratio (SAR), USSL classification, Doneen’s classification and Wilcox’s classification. The influence of anions and cations was done by Piper’s trilinear diagram. Groundwater quality for irrigation purpose during premonsoon season is in doubtful category in almost all parts of the study area.

Women, Water & Well-Being: A Case Study of ‘Kuttadampadam’ in Palakkad, Kerala

The natural resources are repository for the survival of all of us, so they must be used efficiently to meet the present needs while conserving them for future generations. An action to develop capacities from global to household levels for their sustainable management and regulation is required henceforth. Of these natural resources, water resources are most precious. If there is no water; there would be no life on earth. Since ‘water is the elixir of life’, water resource management has been considered as one of the most relevant areas of intervention. Understanding the gender dimensions of water resource management is a starting point for reversing the degradation of water resources. Women play an important role here since they have to access the water resources for almost all the activities on a daily basis. As the women are the strong social agents, effective and improved water preservation techniques could be achieved through their empowerment that may eventually lead to the well-being of the households in particular and of the community in general. Therefore, the major research question posed in this study is to analyze the role of women in the preservation and management of water, an inevitable, precious but diminishing natural resource. The study also intends to describe the relationship between the three ‘W's-Women, Water & Well-being. Both qualitative and quantitative approaches are essential here as it is a contingent issue in the present scenario. Psychological dimensions were also explored since the issue is affecting the routine life of the community. The case study of women belonging to the Kuttadampadam region was done to explain the role of women in preserving water resources in the areas affecting severe water scarcity.

Deciphering the 'Elixir of Life': Dynamic Perspectives into the Allosteric Modulation of Mitochondrial ATP Synthase by J147, a Novel Drug in the Treatment of Alzheimer's Disease.

The discovery of J147 represented a significant milestone in the treatment of age-related disorders, which was further augmented by the recent identification of mitochondrial ATP synthase as the therapeutic target. However, the underlying molecular events associated with the modulatory activity of J147 have remained unresolved till date. Herein, we present, for the first time, a dynamical approach to investigate the allosteric regulation of mATP synthase by J147, using a reliable human αγβ protein model. The highlight of our findings is the existence of the J147-bound protein in distinct structural associations at different MD simulation periods coupled with concurrent open↔close transitions of the β catalytic and α allosteric (ATP5A) sites as defined by Cα distances (d), TriCα (Θ) and dihedral (φ) angular parameters. Firstly, there was an initial pairing of the αγ subunits away from the β subunit followed by the formation of the 'non-catalytic' αβ pair at a distance from the γ subunit. Interestingly, J147-induced structural arrangements were accompanied by the systematic transition of the β catalytic site from a closed to an open state, while there was a concurrent transition of the allosteric site from an open αE conformation to a closed state. Consequentially, J147 reduced the structural activity of the whole αγβ complex, while the unbound system exhibited high atomistic deviations and structural flexibility. Furthermore, J147 exhibited favorable binding at the allosteric site of mATP synthase with considerable electrostatic energy contributions from Gln215, Gly217, Thr219, Asp312, Asp313, Glu371 and Arg406. These findings provide details on the possible effects of J147 on mitochondrial bioenergetics, which could facilitate the structure-based design of novel small-molecule modulators of mATP synthase in the management of Alzheimer's disease and other neurodegenerative disorders.

Zachary A. Matus. Franciscans and the Elixir of Life: Religion and Science in the Later Middle Ages.

Z<scp>achary</scp> A. M<scp>atus</scp>. <i>Franciscans and the Elixir of Life: Religion and Science in the Later Middle Ages</i>.

Extinction of the Elixir of Life: Depletion of Groundwater Level In Chennai

Extinction of the Elixir of Life: Depletion of Groundwater Level In Chennai

Design and Experimentation on Mixed Mode Natural Convection Solar Dehydrator for Ocimum Sanctum

Tulsi (Ocimum Sanctum) is also known as “the elixir of life” since it promotes longevity. Different parts of plant are used in Ayurveda and Siddha Systems of Medicine for prevention and cure of many illnesses and everyday ailments like common cold, headache, cough, flu, earache, fever, colic pain, sore throat, bronchitis, asthma, hepatic diseases, malaria fever, as an antidote for snake bite and scorpion sting, flatulence, migraine headaches, fatigue, skin diseases, wound, insomnia, arthritis, digestive disorders, night blindness, diarrhea and influenza. We can use Tulsi in Powder form, Oil extract, etc. Drying of such kind of Ayurvedic leaves is essential for their further use. Drying is the technique in which moisture of that product removed under standard condition. Conventionally drying is done in open area but there are so many disadvantages of it viz, infection by dust and durt, the product may be contacted with bird’s excreta, dead insects, etc. In order to prevent such product, solar drying is the best technique. In solar drying method we are not only dry the product but also we can reduce the drying time and produce the hygienic product. Solar dryer have shown a very good result in the preservation of the ginger from wastage, poisoning and other contaminants. The solar dryer is solely depending on the renewable energy of the sun. It does not use any fossil fuel for burning.

Oxygen, evolution and redox signalling in the human brain; quantum in the quotidian.

Rising atmospheric oxygen (O2 ) levels provided a selective pressure for the evolution of O2 -dependent micro-organisms that began with the autotrophic eukaryotes. Since these primordial times, the respiring mammalian cell has become entirely dependent on the constancy of electron flow, with molecular O2 serving as the terminal electron acceptor in mitochondrial oxidative phosphorylation. Indeed, the ability to 'sense' O2 and maintain homeostasis is considered one of the most important roles of the central nervous system (CNS) and probably represented a major driving force in the evolution of the human brain. Today, modern humans have evolved with an oversized brain committed to a continually active state and, as a consequence, paradoxically vulnerable to failure if the O2 supply is interrupted. However, our pre-occupation with O2 , the elixir of life, obscures the fact that it is a gas with a Janus face, capable of sustaining life in physiologically controlled amounts yet paradoxically deadly to the CNS when in excess. A closer look at its quantum structure reveals precisely why; the triplet ground state diatomic O2 molecule is paramagnetic and exists in air as a free radical, constrained from reacting aggressively with the brain's organic molecules due to its 'spin restriction', a thermodynamic quirk of evolutionary fate. By further exploring O2 's free radical 'quantum quirkiness', including emergent (quantum) physiological phenomena, our understanding of precisely how the human brain senses O2 deprivation (hypoxia) and the elaborate redox-signalling defence mechanisms that defend O2 homeostasis has the potential to offer unique insights into the pathophysiology and treatment of human brain disease.

The Trademarked Red “Elixir of Life,” Hall’s Coca Wine

The Trademarked Red “Elixir of Life,” Hall’s Coca Wine