Tidal flats are important ecological and terrestrial resources. With the increasing development of coastal engineering projects, it is important to understand the dynamic response of tidal flats to human activities. Hence, the time series of wave, current, and suspended sediment during the spring tide from April 30, 2013 to May 1, 2013 were recorded by three tripod observation systems placed on the upper, middle, and lower parts of the tidal flats south of a constructed harbor in Wanggang, Jiangsu, China. The results showed that eddies formed south of the reclamations during flood tides. The directions of local tidal currents changed from their original southwest to the present northwest, and the ebb tides also changed but continued to flow northeast. The sediment transport process was basically consistent with the currents. The total net sediment fluxes during the tidal cycle (mean values of two tides) on the mudflat were two orders of magnitude larger than those on the salt marsh. Most of the sediments on both the mudflat and the salt marsh were transported northward alongshore, and a small portion of the sediments was transported seaward on the mudflat but shoreward on the salt marsh. The portion of the tidal flat with an elevation >1 m was wide in the north but narrow in the south, as determined by analysis of LiDAR elevation data, which coincided with the local sediment dynamics. The sediments were transported northward from southern deep waters during flood tides, which assisted in the expansion of the tidal flats in the north. This phenomenon reflected unique local sediment dynamics that were highly constrained by reclamations and Dafeng Harbor in the north as well as seawalls in the west. The tidal flat influenced by eddies can extend up to approximately 10 km south of the Dafeng Harbor. This case study has significant implications for the protection of tidal flats and the construction of coastal artificial engineering projects.