The purpose of this article is to study the essence and practice of applying the Supply Chain 4.0 concept at logistics enterprises. The relevance of the research topic is that the issue of digital technologies in supply chains requires in-depth analysis, research and improvement. The research methodology used in this article is a combination of general and special scientific methods: statistical analysis - for grouping and diagnosing data for the study of dynamic trends, graphic method - for visual perception of research results, systematic approach - for systematization of developed studies and substantiating the feasibility of application . concepts of Supply Chain 4.0 at logistics enterprises. The growing role and importance of the digital supply chain in the practices of leading companies to meet customer needs and create value is substantiated. Today, digital technologies have been proven to provide intelligent management of the supply chain, transforming it from a linear model to a model in which information flows from one centralized, multi-directional source. The key elements of Supply Chain 4.0 are considered and its main advantages and disadvantages in practice are characterized. The results of the study of the influence of the digital supply chain on the activities of logistics enterprises at the expense of minimal costs and time are characterized. The main disruptive forces affecting the current supply chain model are considered, among which the following stand out: innovative digital technologies, business ecosystems, the global nature of work, fluctuations in demand and supply. The experience of the world's logistics companies (DHL, Nippon, Express, Maersk) regarding the use of the digital supply chain in practice is highlighted. The results of the implementation of the digital supply chain at logistics enterprises are characterized by the following indicators: the number of perfect orders increases by 40%, customer satisfaction increases by 30%, inventory turnover increases by 10-40% with minimal time and costs.