In this paper, we employ group rings and some known results on group codes to study reversible group DNA codes. We define and study reversible cyclic DNA codes from a group ring point of view and we also introduce the notion for self-reciprocal group ring elements. Moreover, we search for reversible group DNA codes with the use of a virus optimisation algorithm. We obtain many good DNA codes that satisfy the Hamming distance, the reverse, the reverse-complement and the fixed GC-content constraints.