The purpose of the study was to determine the interaction in the systems based on the compounds AgSbP 2 Se 6 and AgSbSe 2 (Sb 4 (P 2 Se 6 ) 3 ). To achieve the goal, 13 samples were synthesized in the AgSbP 2 Se 6 – AgSbSe 2 (Sb 4 (P 2 Se 6 ) 3 ) systems. Synthesis was carried out in evacuated up to 0.13 Pa quartz ampoules. The initial materials were pre-synthesized AgSbP 2 Se6, AgSbSe 2 and Sb 4 (P 2 Se 6 ) 3 . Their synthesis was carried out from high purity elementary components taken in a stoichiometric ratio. The maximum temperature of synthesis was 40-50 K above the melting point of components, including the products of interaction. Homogenizing annealing was conducting at the temperature 573 K for 120 hours. The identification was carried out by differential thermal analysis (DTA) and X-ray powder diffraction (XRD) (DRON 4.07, Cu Kα radiation). Synthesis of alloys was carried out in a similar way. The maximum temperature of the synthesis was 900 K. Annealing was carried out at 573 K for 240 hours. The obtained samples were investigated by DTA and XRD methods. The AgSbP 2 Se 6 – AgSbSe 2 system belongs to the eutectic type with boundary solid solutions based on the starting components. The solubility on the AgSbP 2 Se 6 side is about 5 mol.%, and on AgSbSe 2 – about 8 mol.%. The primary crystallization lines in the system intersect at the eutectic point with coordinates 724 K, ~ 33 mol.% AgSbSe 2 . The homogeneity region of AgSbSe 2 with increasing temperature is strongly expanding and at an eutectic temperature up to 30 mol.%, whereas this is not observed for AgSbP 2 Se 6 . The synthesized samples in AgSbP 2 Se 6 – Sb 4 (P 2 Se 6 ) 3 system were compact ingots with a rather dim metallic shine. The indexing of the X-ray powder diffractograms show that two phases AgSbP 2 Se 6 and Sb 4 (P 2 Se 6 ) 3 are exist in the system. On the thermograms of samples two endothermic effects were observed. The temperature of the low-temperature endothermic effect practically did not change in the whole concentration range (5 – 95 mol.%), which indicated the eutectic interaction. Invariant eutectic point is located on the side of Sb 4 (P 2 Se 6 ) 3 , its coordinates are 646 K, ~ 96 mol.% Sb 4 (P 2 Se 6 ) 3 . The solubility areas based on the initial components at annealing temperature do not exceed 5 mol%.