Prominent new peaks in the spectra of O2, CO, NO, CO2, and N2O at energy losses from 18 to 40 eV have been observed by high energy (25 keV) low resolution (2.5 eV) electron impact spectroscopy at squared momentum transfer (K2) values larger than 2 a.u. However, no such isolated features were observed in CS2, C2H2, H2O, SO2, CH4, C2H6, C2H4, benzene, isobutane, methanol, acetone, and trichloroethylene in spite of the presence of significant background oscillator strength. For those molecules in which isolated peaks were observed possible electronic transitions have been suggested.