Plasma Electrolytes Research Articles

Research on electrolytic plasma polishing process for internal flow channel of superalloys alloy additive manufacturing parts

To solve the problem of poor surface quality of internal channel parts in additive manufacturing, the internal electrode electrolyte plasma polishing technology was used to improve the surface quality of the workpiece. The influence of different process parameters on the surface roughness of the internal channel was studied by orthogonal test. The experimental results show that for small caliber channels, polishing is more suitable for low voltage conditions. Under the conditions of polishing voltage 40 V, electrolyte temperature 80°C, moving speed of cathode wire 3 mm/min, and peristaltic pump speed 100 rpm, the roughness of the GH3536 inner channel sample is reduced from 15.1 to 2.793 μm. The order of influence of each factor is as follows: firstly voltage, secondly electrolyte temperature, then cathode wire traveling speed, and finally peristaltic pump speed. The roughness of GH4169 was reduced from 6.724 to 0.47 μm by polishing experiment. The results of the internal surface performance test show that the spherical powder on the surface of the workpiece disappears after polishing through the internal flow channel, the electrolyte component residue is not detected on the surface of the internal flow channel, and the corrosion resistance is significantly improved.

Enhanced wear resistance, hydrophobic properties and corrosion resistance of plasma electrolyte oxidation coatings on Ti6Al4V alloys via addition of ZrO2 nanoparticles

Enhanced wear resistance, hydrophobic properties and corrosion resistance of plasma electrolyte oxidation coatings on Ti6Al4V alloys via addition of ZrO2 nanoparticles

A precise machining surface obtained electrolyte plasma polishing on Ti–6Al–4V alloy: Microstructure and in-situ mechanical behaviors

A precise machining surface obtained electrolyte plasma polishing on Ti–6Al–4V alloy: Microstructure and in-situ mechanical behaviors

Fractional hyper-ballistic transport under external oscillating electric fields.

The generalized Langevin equation (GLE) for a tagged particle in a liquid of charged particles under the influence of external AC electric fields is studied. For the fractional memory kernel in the GLE, the mean square displacement (MSD) of the particle is studied analytically in both the underdamped and overdamped regimes. The MSD consists of a part corresponding to the absence of the external field and a part affected by the external field, which is expressed through the mean velocity of the particle. We have identified the time windows when the particle shows unusual behaviors in the oscillating fields including hyper-ballistic diffusion, thus generalizing the results for the memoryless Brownian motion. The theory of Brownian motion, since the time of Einstein and Langevin, has overcome a stormy development and the methods of the description of the irregular movement of small particles in solutions have found use in several areas of science. The time dependence of the key quantities in this theory, such as the particle's MSD in condensed matter physics, has been shown to be anomalous, that is, different from linear, in many experimental observations. The movement of the observed particle shows correlation properties of the thermal noise of the surrounding environment, which can be very different in different systems and are associated with memory effects in the dynamics of the particle. One option, effective in describing complex systems by the method of the GLE, is the use of the fractional kernel of its frictional memory integral that replaces the Stokes friction force in the original Langevin equation of motion. In our work, for the first time, we solve such a GLE with a fractional memory for a particle-in-bath system (the particle can be identical with the surrounding particles) in an external oscillating electric field. All particles are charged, as is the case, for example, in plasma or liquid electrolytes, so both the monitored particle and its surroundings are affected by the external field. The GLE is solved analytically for the entire time scale. The results include solutions to the classical memoryless Langevin equation and new features in the time dependence of the MSD, including unusual near-ballistic or hyper-ballistic particle transport, depending on the way the external AC field is applied.

Impact of voltage variation on topography, hydrophobicity, and corrosion behavior of the CeO2-TiO2 nanocomposite coating on AM60B Mg alloy prepared by plasma electrolyte oxidation

Abstract A superhydrophobic oxide layer on AM60B magnesium alloy was created by using a plasma electrolytic oxidation (PEO) technique and subsequent surface modification. PEO was applied in an electrolyte with/without CeO2-TiO2 nanoparticles (NPs) by two different voltages of 350 and 450 V. Atomic force microscopy (AFM) and field emission scanning electron microscopy (FE-SEM) were used to evaluate the roughness and morphology of the surface. Water contact angles on the surface were measured to investigate the surface wettability. Potentiodynamic polarization tests in a 3.5 wt% NaCl solution were used to assess the corrosion resistance of the coating. Also, the FE-SEM images showed that increasing applied voltage, decreases the numbers and size of the pores on the surface. Results showed that applying PEO, increased the corrosion resistance of the bare AM60B because corrosion rate (C.R.) decreased from 1.523805 (bare AM60B) to 1.432107 mpy (PEO-450 V). Furthermore, using CeO2-TiO2 NPs effectively enhanced the corrosion resistance of the bare AM60B by decreasing the corrosion rate from 1.523805 to 1.286469 mpy.

Tenofovir alafenamide compared to tenofovir disoproxil fumarate, induces dysglycemia, and dyslipidemia in Wistar rats.

To determine the metabolic effects of tenofovir alafenamide (TAF) compared to tenofovir disoproxil fumarate (TDF) in vivo . Male Wistar rats ( Rattus novergicus , 250-300 g body weight) were divided into three groups ( n = 8) and orally treated daily with 1.0 ml distilled water (group 1), TAF (0.42 mg/kg) (group 2), or TDF (5.0 mg/kg) (group 3), respectively, for 56 days. Glucose tolerance tests were done before the animals were sacrificed by halothane overdose, and blood was collected by cardiac puncture for the analysis of plasma lipids, electrolytes, and insulin. The kidney and pancreatic tissues were excised and homogenized to measure oxidative stress. Compartmentation of TAF and TDF was determined in NRK-52 and peripheral blood mononuclear cells (PBMCs). There were no significant differences in weight gain among controls, TAF- or TDF-treated rats. TAF-treated rats had significantly increased fasting blood glucose (FBG), fasting plasma insulin (FPI), insulin resistance, impaired glucose tolerance, and dyslipidemia compared to control or TDF-treated rats, respectively. There was increased lipid peroxidation in the pancreas of TAF-treated compared to TDF-treated or control animals, respectively. TDF- treated rats presented with symptoms of Fanconi syndrome compared to TAF-treated or control animals, respectively. Kidney homogenates from TDF-treated animals had significantly reduced antioxidant enzyme activity compared to TAF-treated animals or controls, respectively. Intracellular concentrations of TAF were significantly higher than TDF in both NRK-52E cells and PBMC, respectively. TAF treatment is weight-neutral and causes dysglycemia, and dyslipidemia but not Fanconi syndrome compared to TDF.

Association of thyroid hormones with the severity of chronic kidney disease: a cross-sectional observational study at Tabuk, Saudi Arabia.

The interplay between chronic kidney disease (CKD) and thyroid dysfunction is becoming more evident in the biomedical community. However, the intricacies of their relationship warrant deeper investigation to understand the clinical implications fully. This study aims to systematically evaluate the correlation between thyroid hormone levels, including thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4), and markers of renal disease severity. These markers include serum creatinine, urea, and parathyroid hormone (PTH) levels in individuals diagnosed with CK). We conducted a cross-sectional observational study involving a cohort of 86 participants with CKD recruited from the renal clinic at King Fahad Hospital in Tabuk. Biochemical parameters, encompassing plasma electrolytes and thyroid hormone concentrations, were quantitatively assessed. These measurements were performed with the aid of a Roche Cobas E411 analyzer. The Pearson correlation coefficient was employed to delineate the strength and direction of the associations between the thyroid function markers and renal disease indicators. The statistical analysis highlighted a generally weak correlation between the concentrations of thyroid hormones and the indicators of renal disease severity, with Pearson correlation coefficients between -0.319 and 0.815. Critically, no significant correlation was found between creatinine and thyroid hormones (TSH, T3, T4), nor was any substantial correlation between urea and thyroid hormones. Conversely, a robust positive correlation was noted between the levels of parathyroid hormone and serum creatinine (r=0.718, p<0.001). The data suggests that thyroid hormone levels have a minimal correlation with the severity of renal disease markers. In contrast, the pronounced correlation between PTH and creatinine underscores the importance of considering PTH as a significant factor in managing and therapeutic intervention of CKD complications. These initial findings catalyze further research to thoroughly investigate the pathophysiological relationships and potential therapeutic targets concerning thyroid dysfunction in patients with renal impairment.

Enhanced hydrophobic properties, wear and corrosion resistance of plasma electrolyte oxidation coatings on AZ31B magnesium alloys with addition of TiO2 nanoparticles

Enhanced hydrophobic properties, wear and corrosion resistance of plasma electrolyte oxidation coatings on AZ31B magnesium alloys with addition of TiO2 nanoparticles

Surface finishing of 3D-printed Ti–6Al–4 V alloy by electrolyte plasma polishing: Process optimization and microstructure

Surface finishing of 3D-printed Ti–6Al–4 V alloy by electrolyte plasma polishing: Process optimization and microstructure

8365 Bilateral Adrenal Hemorrhage Unveiling Adrenal Metastases In A Patient With Retroperitoneal Sarcoma

Abstract Disclosure: R.J. Shah: None. A.C. Goldberg: None. S. Jasim: None. Introduction: Metastatic disease to the adrenal gland is the most commonly occurring malignancy of the adrenal glands. Adrenal hemorrhage (AH) however is a rare but potentially fatal manifestation of malignancy. This case report highlights the unusual presentation of retroperitoneal sarcoma, manifesting as bilateral adrenal hemorrhage in the context of underlying metastases. Case Presentation: A 53-year-old man presented with a 4-week history of fatigue, intermittent abdominal pain radiating to the back, and vomiting. CT revealed bilateral adrenal masses measuring up to 8.5cm on the left side, with Hounsfield units (HU) 27, and 5.9cm on the right, HU 27, consistent with large areas of bilateral adrenal hemorrhage later confirmed on MRI. Biochemical evaluation included ACTH-stimulated cortisol, which was borderline at 17.4mcg/dl (recommended above 18-20mcg/dl), with a significantly elevated ACTH level of 103.8pg/nl (reference range 7.0-63.0pg/ml). Plasma metanephrines, electrolytes, aldosterone, and DHEA-S were normal. Although hemodynamically stable, he was started on prednisone 5mg daily as he was at high risk for primary adrenal insufficiency (AI). He was referred to endocrine surgery and further workup with PET/CT demonstrated a new FDG-avid periaortic retroperitoneal mass, with an interval increase in the size of the adrenal masses and development of hypoattenuating lesions in the kidneys and pancreas favoring aggressive metastatic disease. He underwent biopsy of the retroperitoneal mass, and pathology was consistent with high-grade sarcoma. Oncology started treatment with dexrazoxane and doxorubicin. His adrenal masses remained unchanged in size, and the patient died related to rapid progression of disease. Discussion: Spontaneous bilateral adrenal hemorrhage is rare with a reported incidence of 0.14 to 1.8%. Although most cases have been associated with sepsis, anticoagulation, hematologic disorders and trauma, it is important to maintain a high level of suspicion for underlying adrenal tumors and metastatic disease. AH can be a diagnostic challenge because of its non-specific presentation, and imaging is vital for timely recognition. Patients with bilateral AH should be managed with corticosteroids to avert AI-related fatalities. Presentation: 6/1/2024

Proton pump inhibitor-induced hypomagnesemia, a rare cause of reversible delirium: A case report with literature review.

Hypomagnesemia is associated with multiple electrolyte disturbances such as hypokalemia, hypocalcemia and hypoparathyroidism. Proton pump inhibitors (PPIs) are widely used in gastrointestinal disorders and are generally considered safe by clinicians. However, it is unusual side effect of hypomagnesemia is potentially under-recognized. Delirium is usually thought to be a clue of cerebrovascular disease, and the association between delirium and hypomagnesemia is unexpected. We describe a patient used PPI with hypomagnesemia showed normal parathyroid hormone (PTH) despite hypocalcemia and reversible delirium. To enhance clinicians' vigilance, we performed a literature review on cerebellar syndromes due to hypomagnesemia. A 74-year-old woman was admitted to our hospital with intermittent nausea, vomiting, hand tremors, and delirium. Laboratory analysis showed hypokalemia, hypomagnesemia, and normal parathyroid hormone despite hypocalcemia, physical examination showed horizontal nystagmus and the brain MRI was negative. Surprising, detailed medical history revealed that the etiology was the usage of omeprazole. Omeprazole was discontinued and oral supplementation with magnesium, calcium, and potassium was administered. Delirium quickly disappeared and the serum potassium, magnesium, and calcium levels gradually normalized; at discharge, nystagmus gradually disappeared, and plasma electrolyte levels were stable at follow-up. Hypomagnesemia is associated with a variety of neurological symptoms up to life-threatening conditions if left untreated; as Mg is not present in routine electrolyte panels, hypoparathyroidism, hypokalemia, and delirium may be a clue, and physicians must be alert to consider PPI as a potential cause of unexplained hypomagnesemia, and timely treatment to avoid sequelae.

Effects of diluted seawater in drinking water on physiological responses, feeding, drinking patterns, and water balance in crossbred dairy goats

Background and Aim: In tropical regions, the intrusion of saline from seawater (SW) due to global warming and sea level rise in recent years is an important natural factor influencing goat well-being. This study aimed to determine the effects of diluted SW in drinking water on the physiological responses and eating and drinking patterns of crossbred dairy goats under tropical conditions. Materials and Methods: Twenty dairy goats were divided into four groups (five animals each) based on body weight and milk yield. Animals received either fresh drinking water (SW0.0, control) or diluted SW at concentrations of 0.5% (SW0.5, low salinity), 1% (SW1.0, moderate salinity), and 1.5% (SW1.5, high salinity). The experiment was performed for 49 days (1st–7th week). Throughout this period, daily food and water intake were measured every day. In addition, blood collection was performed on day 25. Total urine and feces were collected from days 25 to 29. Meal and drinking patterns were determined on days 31 and 32. Results: Salinity did not influence dry matter intake throughout the experiment (p &gt; 0.05). However, SW had a significant effect on eating patterns. The effect of SW on water intake (WI) was pronounced from the 2nd to 7th weeks of this experiment (p &lt; 0.05). The water balance decreased and plasma antidiuretic hormone levels increased from SW1.5 to SW2.5 compared to the other treatments. Rectal temperature and respiration rate increased from 15:00 to 17:00 in SW1.5 patients. The concentrations of plasma electrolyte, creatinine, and heat shock protein 70 did not differ between treatments (p &gt; 0.05). The urinary excretion of Na+ from SW1.5 and K+ and Cl- from SW1.0 was higher than that from SW0.0 and SW0.5 (p &lt; 0.01). Conclusion: Lactating crossbred goats adapted to low and moderate SW by increasing urine volume and urinary electrolyte excretion (Uex), whereas animals responded to high SW by either increasing Uex or altering drinking patterns to minimize salt stress. Keywords: antidiuretic hormone, dairy goat, kidney, saline water, water balance.

Engineering of multilayered coating on additively manufactured Ti-6Al-4V porous implants to promote tribological and fatigue performances

Engineering of multilayered coating on additively manufactured Ti-6Al-4V porous implants to promote tribological and fatigue performances

Workpiece surface laser regulation in laser-induced plasma electrolyte jet machining: Position, shape, and energy

Workpiece surface laser regulation in laser-induced plasma electrolyte jet machining: Position, shape, and energy

Extreme founder effect associated with hyperglycemia and hyperlipidemia on the island of NIAS/Indonesia

Extreme founder effect associated with hyperglycemia and hyperlipidemia on the island of NIAS/Indonesia

Plasma Electrolytes Response in Mud Catfish, Clarias gariepinus (Burchell 1822) exposed to Different Regimes of Salinity and pH

Introduction: Aquatic organisms, especially fish, are highly sensitive to environmental changes that can profoundly affect their physiological processes essential for survival. Physico-chemical factors such as salinity and pH exert significant influences on osmoregulation and ion balance, which are critical for maintaining cellular homeostasis in fish. Aims: This study aims to explore how varying levels of salinity and pH affect plasma electrolyte concentrations in Clarias gariepinus, focusing on potassium (K+), sodium (Na+), chloride (Cl−), and bicarbonate (HCO3−) ions. The objective is to understand the physiological responses of C. gariepinus to these environmental factors and their potential as biomarkers for assessing aquatic ecosystem health. Materials and Methods: Juvenile C. gariepinus was exposed to different salinity levels (4 ‰, 6 ‰, 8 ‰) and pH levels (4, 6, 8) over 21 days. Plasma electrolyte concentrations were measured using an SFRI ISE 6000 Electrolyte Analyser. Statistical analysis included ANOVA and DMRT to identify significant differences (p &lt; 0.05) among experimental groups. Results: The study found significant variations in K+, Cl−, Na+, and HCO3- concentrations in C. gariepinus across different salinity and pH conditions. K+ levels decreased with increasing salinity, indicating stress-induced responses, while pH variations had less pronounced effects on K+ regulation. Cl− concentrations increased with higher salinity levels, suggesting adaptive osmoregulatory strategies. Na+ levels showed significant fluctuations across salinity and pH conditions, whereas HCO3− levels responded uniquely to changes in these parameters, demonstrating adaptive mechanisms in acid-base balance. Conclusion: This research underscores the adaptive responses of C. gariepinus to fluctuations in salinity and pH, highlighting their ability to maintain plasma electrolyte balance under varying environmental conditions. These findings contribute to understanding the ecophysiological adaptations of C. gariepinus and suggest the potential utility of plasma electrolytes as biomarkers for assessing the health of aquatic ecosystems.

Hematological toxicity of disinfection by-product iodoacetic acid

To clarify the effect of iodoacetic acid(IAA) on the blood system and electrolyte balance, hence further study the intrinsic relation of blood routine parameters and electrolyte levels, major hematological toxicity effects and their pattern after IAA treatment. Forty-eight 21-day-old male SPF grade Sprague-Dawley(SD) rats were gavaged with 0, 6.25, 12.5 and 25 mg/kg IAA for 31 days. After detections of blood routine and plasma inorganic ion levels, Spearman correlation coefficients were performed to evaluate their relationship. Changes in ferritin, transferrin, hepcidin, C-reactive protein and glyceraldehyde-3-phosphate dehydrogenase(GAPDH) were assessed by enzyme-linked immunosorbent assays. The EDock bioinformatics tool was applied to docking model of IAA and GAPDH. Compared to the control, high-dose IAA exposure had obvious inhibition effect on rat leukocytes with the total number declined by 51.12%, and neutrophils were particularly sensitive to IAA with the number reduced by 73.66%(P&lt;0.01), and rat erythrocytes exhibited a small cell low pigment effect with hemoglobin and hematocrit decreased by 8.60% and 8.70%, respectively(P&lt;0.05). But IAA had little effects on the platelet. Plasma iron, phosphorus, zinc and potassium levels were repressed significantly, while chlorine, sodium and magnesium levels were elevated obviously through IAA exposure. However, plasma calcium levels were hardly affected by IAA. In comparison with the control, iron levels declined by 67.09%, whereas magnesium levels increased by 131.82% in the high-dose group(P&lt;0.01). Overall, correlation analyses uncovered that plasma iron metabolism was most strongly and positively correlated with levels of leukocyte, erythrocyte and platelet system parameters after IAA exposure, and the correlation coefficients of leukocyte number, mean hemoglobin content and mean erythrocyte volume were 0.637, 0.410 and 0.365, respectively(P&lt;0.05). Compared to the control, in the high-dose IAA group, the plasma content of C-reactive protein was significantly upregulated by 13.30%(P&lt;0.05), and plasma levels of transferrin and ferromodulin were also respectively elevated by 12.73% and 11.02%(P&lt;0.05). But plasma levels of ferritin and GAPDH did not differ between groups. The docking model exhibited that IAA could bind to the 150 Cys active site of rat GAPDH did. IAA not only had toxic effects on rat leukocytes and the plasma electrolyte balance, but also generated inflammation and iron deficiency, leading to smaller erythrocytes and lower pigment.

Fabrication of a durable corrosion-resistant superamphiphobic CeO2–TiO2 ceramic nanocomposite coating on AZ31B Mg alloy by plasma electrolyte oxidation

Fabrication of a durable corrosion-resistant superamphiphobic CeO2–TiO2 ceramic nanocomposite coating on AZ31B Mg alloy by plasma electrolyte oxidation

Assessing the properties of biodegradable magnesium alloy AZ31 protected by a polymer layer on a plasma electrolytic oxidized (PEO) surface

Assessing the properties of biodegradable magnesium alloy AZ31 protected by a polymer layer on a plasma electrolytic oxidized (PEO) surface

Water structural effects on DNA–DNA interactions and homologous recognition

Water structural effects on DNA–DNA interactions and homologous recognition