In this article, an accurate and efficient computational method of system-level electrostatic discharge (ESD) noise waveforms in a field-coupled ESD test of the ISO 10605 standard using a 3-D full-wave solver is proposed. To apply efficient computational methods to the ESD test simulation, the split-domain approach and decomposition method are first individually validated with a simple structure. Next, a method simultaneously using the decomposition method and split-domain approach is proposed and validated with the separately given field source data. Using the proposed method with the measured electromagnetic fields radiated from an ESD generator, the ESD noise waveforms in the ISO 10605 field-coupled ESD test are accurately and efficiently computed by considering not only the ESD current coupling but also the radiated coupling from the ESD generator.