Propagation Of Electrical Signals Research Articles

A cleaner and eco-friendly approach to simultaneous extraction and characterization of essential oil and pectin from Assam lemon peel and its application for energy generation through TENG devices

Scientists have been working on developing a green bio-TENG for portable remote devices, including wearables in the biomedical sector. The process involves obtaining pectin, a green material with anti-microbial properties, as a Triboelectric material. This study focuses on the extraction of essential oil (EO) and pectin from Assam lemon peel simultaneously. A single-step strategy was optimized using a central composite design-based response surface approach. The extracted pectin yielded 4.19 ± 0.31 % and 11.53 ± 0.11 %, respectively. GC-MS analysis revealed 52 volatile components in the Assam lemon EOs, with limonin being 94.47 % and β-Bisabolene being 1.26 %. Only khusilal was found in the EOs, a rare discovery in the scientific domain. The extracted pectin showed good purity and antimicrobial properties. The in vitro activities of the citrus EO against microbial cultures revealed its activity in controlling and eradicating bacterial and fungal growth. Hydro distillation followed by enzyme treatment is a promising approach that combines two separate extraction procedures. The produced biopolymer showed the generation of electrical signals under minimal pressure and stretching and prevented microbial degeneration when applied to a nanogenerator.

Harnessing 3D Printing and Electrospinning for Multiscale Hybrid Patches Mimicking the Native Myocardium.

Engineered cardiac tissues show potential for regenerative therapy in ischemic heart disease. Yet, selection of soft biomaterials for scaffold manufacturing is primarily influenced by empirical and compositional factors, raising concerns about arrhythmic risks due to poor electrophysiological integration. Addressing this, we developed multiscale hybrid myocardial patches mimicking native myocardium's structural and biomechanical attributes, utilizing 3D printing and electrospinning techniques. We compared three patch types: pure silicone and silicone-poly(lactic-co-glycolic acid) (PLGA) with random (S-PLGA-R) and aligned (S-PLGA-A) fibers. S-PLGA-A patches with fiber orientation angles of 95-115° are achieved by applying a secondary electrical field using two parallel aluminum enhancers. With bulk and localized moduli of 350-750 and 13-20 kPa resembling the native myocardium, S-PLGA-A patches demonstrate a sarcomere length of 2.1 ± 0.2 μm, ≥50% higher strain motions and diastolic phase, and a 50-70% slower rise of calcium handling compared to the other two patches. This enhanced maturation and improved synchronization phenomena are attributed to efficient force transmission and reduced stress concentration due to mechanical similarity and linear propagation of electrical signals. This study presents a promising strategy for advancing regenerative cardiac therapies by harnessing the capabilities of 3D printing and electrospinning, providing a proof-of-concept for their effectiveness.

Nonlinear dynamic wave characteristics of optical soliton solutions in ion-acoustic wave

Traveling wave solutions are utilized to depict reaction-diffusion and analyze electrical signal transmission and propagation in space-time nonlinear fractional order partial differential equations like the space-time fractional Telegraph and Kolmogorov-Petrovsky Piskunov equations, and that are used in physical science to model combustion, biological research to model nerve impulse propagation, chemical dynamics to model concentration in order wave propagation, and plasma to model the progression of a set of duffing oscillators. In this study, the new generalized (G′/G)−expansion technique was employed to construct some novel and more universal closed-form traveling wave solutions in the sense of conformable derivatives which explain the above-stated phenomena properly. By utilizing complex fractional transformation, the ordinary differential equations are generated from fractional order differential equations. The recommended technique allowed us to produce some dynamical wave patterns of kink, single soliton, compacton, periodic shape, multiple periodic waves, anti-kink, and other structures are developed, which are shown using 3D plots and contour plots to illustrate the physical layout clearly. The traveling waveform responses can be defined in terms of functions based on trigonometry, hyperbolic operations, and rational functions and that are quick, flexible, and simple to reproduce. Furthermore, the obtained closed-form solutions for nonlinear fractional evolution equations make stability analysis and accuracy comparison amongst numerical solvers easier, which asserts that the new generalized (G′/G)−expansion technique is one of the most proficient and effective approaches.

Acquired control over proliferation and differentiation of ventricular cardiomyocytes to break down the mechanisms of cardiac repair

Abstract Funding Acknowledgements None. Loss of myocardial tissue remains a leading cause of morbidity and mortality by causing heart rhythm disturbances and heart failure. The (pre-)clinical effects of inducing cardiac regeneration by cardiac cell therapy have been disappointing. In order to find new curative options for these disabling cardiac diseases a shift of focus towards steering the heart to regenerate itself is needed. The aim of this study was to generate a robust ventricular cardiomyocyte model in which proliferation and differentiation could be tightly controlled to investigate cardiac regeneration. To accomplish this we have generated a line of immortalized neonatal rat ventricular cardiomyocytes (nrVMs) through expression of the cell cycle regulators cyclin-dependent kinase 4 and cyclin D1 (CDK4-D1). The CDK4-D1 expressing nrVMs were positive for the proliferation marker Ki67 in contrast to control nrVMs. Cardiomyogenic differentiation could still be induced after multiple passages (> passage 10) as evidenced by immunocytochemistry and optical voltage mapping. These contractile and excitable cells were indeed positive for the cardiac-specific sarcomeric proteins alpha actinin and troponin T in a sarcomeric pattern similar to native nrVMs. Passaging of the control nrVM cultures, however, ultimately led to a senescent cell population lacking sarcomeric markers after passage 3. Electrophysiological analysis of immortalized monolayers, after inducing cardiomyogenic differentiation, showed not only uniform propagation of electrical signal throughout the cultures, but also re-entrant activity although at low frequency. In conclusion, these data show that were able to immortalize ventricular cardiomyocytes by preserving their contractile and excitable phenotype upon significant expansion. Further optimisation of this model will lead to a research model of ventricular cardiomyocytes which will give us the opportunity to unravel the process of cardiomyogenesis and uncover mechanisms which could allow us to enhance the ability of the heart to regenerate itself.

Modeling Excitable Cells with Memristors

This paper presents an in-depth analysis of an excitable membrane of a biological system by proposing a novel approach that the cells of the excitable membrane can be modeled as the networks of memristors. We provide compelling evidence from the Chay neuron model that the state-independent mixed ion channel is a nonlinear resistor, while the state-dependent voltage-sensitive potassium ion channel and calcium-sensitive potassium ion channel function as generic memristors from the perspective of electrical circuit theory. The mechanisms that give rise to periodic oscillation, aperiodic (chaotic) oscillation, spikes, and bursting in an excitable cell are also analyzed via a small-signal model, a pole-zero diagram of admittance functions, local activity, the edge of chaos, and the Hopf bifurcation theorem. It is also proved that the zeros of the admittance functions are equivalent to the eigen values of the Jacobian matrix, and the presence of the positive real parts of the eigen values between the two bifurcation points lead to the generation of complicated electrical signals in an excitable membrane. The innovative concepts outlined in this paper pave the way for a deeper understanding of the dynamic behavior of excitable cells, offering potent tools for simulating and exploring the fundamental characteristics of biological neurons.

Analytical and numerical solutions to the Klein–Gordon model with cubic nonlinearity

In this paper, the nonlinear Klein–Gordon equation’s exact solutions are obtained through the application of an appropriate transformation based on He’s semi-inverse approach. This equation considered a generalization of other famous models in applied science, such as Phi-4 equation, Duffing equation, Fisher–Kolmogorov model through population dynamics and Hodgkin–Huxley equation that characterizes the propagation of electrical signals via nervous system. The suggested approach is simple, robust, and efficient, and its application in other partial differential equations in applied science seems promising. Numerical solution of the nonlinear Klein–Gordon equation is presented using finite difference method. The method’s accuracy is demonstrated by contrasting it with the exact solution that we obtained. The Von Neumann stability technique is applied to obtain the stability condition and a convergent test is presented Some 2D and 3D graphs matching to chosen solutions are simulated by taking into account appropriate values for the parameters.

Local field potential journey into the Basal Ganglia

Local field potentials (LFP) in the basal ganglia (BG) have attracted considerable research and clinical interest. The genesis of these signals has been a topic of extensive discourse, focusing on whether they are a manifestation of local synaptic activity or result from the propagation of electrical signals through tissue, as described by the Maxwell equations (volume conduction). To investigate this, we conducted simultaneous recordings of LFPs from two cortical areas— the dorsolateral prefrontal cortex (DLPFC) and the primary motor cortex (M1)—and various sites within the BG nuclei in an awake, non-task-engaged non-human primate (NHP). Employing innovative analytical techniques, we discerned significant cross-correlations indicative of potential connections, while filtering out non-significant correlations. This allowed us to differentiate between synaptic inputs and volume conduction. Our findings indicate two distinct propagation pathways of BG field potentials emanating from the M1 and the DLPFC, each characterized by different temporal delays. The results imply that these anatomical pathways are differentially influenced by the mechanisms of volume conduction and synaptic transmission. Notably, the M1 exhibits more functional links with non-zero-time delays to the BG structures, while the DLPFC-BG connections are marked by zero-time delays, suggesting a predominance of volume conduction effects. Consequently, investigations into the origins of BG LFP should account for the distinct anatomical pathways linking the cortex and the BG, as they differentially represent information flow and volume conductance.

Dynamical analysis of the FitzHugh–Nagumo model with memristive synapse

Understanding the transition mechanism between different activity patterns in realistic neuron models brings forward fundamental challenges for the dynamical systems theory. The knowledge about the mechanisms can present precious predictions and intuitions for determining fundamental principles of neuron functioning. This paper aims to present a dynamic analysis of the FitzHugh–Nagumo neuron model with a memristive synapse. In this article, the effects of memristive synapse's conductance gain, applied current, and the speed of electrical signal propagation along axons and dendrites on the system's behavior and the neuron's membrane potential are investigated. Analyzes are performed by investigating bifurcation and Lyapunov exponent diagrams versus various model parameters. The physiological role of some parameters and the effect of parameter changes on the model behaviors are discussed. The results demonstrate that when no current is applied to the system, the maximum value of membrane potential is larger, and also, a lower memristive synapse conductance gain leads to a larger maximum value of membrane potential. So, it can be concluded that the neuron in an amplitude death state may be triggered and start firing by decreasing the conductance gain or not applying current.

Effect of the General Anaesthetic Ketamine on Electrical and Ca2+ Signal Propagation in Arabidopsis thaliana

The systemic electrical signal propagation in plants (i.e., from leaf to leaf) is dependent on GLUTAMATE RECEPTOR-LIKE proteins (GLRs). The GLR receptors are the homologous proteins to the animal ionotropic glutamate receptors (iGluRs) which are ligand-gated non-selective cation channels that mediate neurotransmission in the animal’s nervous system. In this study, we investigated the effect of the general anaesthetic ketamine, a well-known non-competitive channel blocker of human iGluRs, on systemic electrical signal propagation in Arabidopsis thaliana. We monitored the electrical signal propagation, intracellular calcium level [Ca2+]cyt and expression of jasmonate (JA)-responsive genes in response to heat wounding. Although ketamine affected the shape and the parameters of the electrical signals (amplitude and half-time, t1/2) mainly in systemic leaves, it was not able to block a systemic response. Increased [Ca2+]cyt and the expression of jasmonate-responsive genes were detected in local as well as in systemic leaves in response to heat wounding in ketamine-treated plants. This is in contrast with the effect of the volatile general anaesthetic diethyl ether which completely blocked the systemic response. This low potency of ketamine in plants is probably caused by the fact that the critical amino acid residues needed for ketamine binding in human iGluRs are not conserved in plants’ GLRs.

Fingerprint-inspired biomimetic tactile sensors for the surface texture recognition

A bionic tactile device is designed for object surface texture recognition, taking inspiration from the microstructure of human fingerprints. The sense of touch in humans is achieved through the frictional vibration and generation of electrical potential signals by subcutaneous receptors. Constructing a tactile sensing device involves generating distinct signals upon interacting with different materials. The piezoelectric film PVDF is particularly suitable as a sensitive material for sensors due to its excellent flexibility, strong mechanical strength, excellent dynamic response and cost-effectiveness. This paper presents the design of a PVDF-based fingerprint-inspired tactile sensor capable of differentiating various textures. By combining the collected signals with machine learning algorithms, diverse textures can be effectively identified. To demonstrate the sensor’s superior performance, two experiments were conducted—one focused on recognizing different material textures, and the other on recognizing Braille characters. The accuracy achieved in these experiments was 97.4% and 96.5%, respectively, highlighting the technology’s significant potential in intelligent robotics and human-computer interaction.

Electromagnetism - Properties of Erythrocytes

At the onset of blood flow, red blood cells (RBCs) align along the central plane of the vessels. In capillaries, RBCs transform from a biconcave disk into a parachute shape. As blood transitions from the arterial to the venous end, the hemoglobin in erythrocytes alters its magnetic susceptibility. Within approximately 0.6-0.8 seconds, oxygen is displaced from RBCs through diffusion. This study explores the fundamentals and interconnections of these processes.
 
 Blood samples from 35 different healthy individuals were analyzed. The research examined magnetic field induction in ferromagnetic toroids, formed by the alternative electric field with a square wave signal, and studied the AC in the secondary coil - a tube filled with blood. This study discusses the impact of RBC geometry and hemoglobin allosteric transitions on electric signal generation and its relevance to cellular metabolic activity in the body.
 
 The findings suggest that the AC field, originating from the heart's rotational dipole, can generate a magnetic field in RBCs, facilitating the allosteric transformations of hemoglobin. Hemoglobin's thermoelastic expansion and magnetostriction cause biconcave membrane oscillations at ultrasound frequencies. The resulting electroacoustic wave rotates charges at the cell's z-potential area, aids RBC migration into the flow plane, and enhances trans capillary diffusion of substances.
 
 An electroacoustic standing wave emerges between the oscillating RBCs, coinciding with the wavenumber of externally penetrating infrared light. The synergic influence on hemoglobin in capillaries causes the RBC membrane to create a temporally frequency-modulated wave, carrying resonance molecular frequencies. This wave regulates biochemical processes within and outside body cells.

Low-noise co-arm differential sensor for an optical frequency comb sampling an E-field test system.

Optical frequency comb (OFC) technology can realize the rapid measurement of electric fields (E-fields) with large bandwidth. However, this technology suffers from the problem of high intensity noise, resulting in low sensitivity and a blind frequency region. In order to solve the above problems, a dual-path optical E-field sensor with a common reference arm based on a lithium niobate optical waveguide is proposed. The introduction of the reference arm improves the balance of optical paths and the degree of integration. A segmented electrode is also designed to ensure the generation of reverse electrical signals on two Mach-Zehnder interferometers (MZIs). After exiting from the differential photodetector (PD), the intensity noise can be removed, and the sensitivity of the sensor can be improved. After testing, the maximum intensity noise reduction is about 37 dB, the average noise reduction is about 22.3 dB, and the blind frequency region can be eliminated with the co-arm differential optical E-field (CDOE) sensor in the process of measuring the signal. This sensor can be used in the 1 MHz-12 GHz bandwidth with a sensitivity better than 10 mV/m·√Hz.

Rapid, Tough, and Trigger-Detachable Hydrogel Adhesion Enabled by Formation of Nanoparticles In Situ.

Integrating hydrogel with other materials is always challenging due to the low mass content of hydrogels and the abundance of water at the interfaces. Adhesion through nanoparticles offers characteristics such as ease of use, reversibility, and universality, but still grapples with challenges like weak bonding. Here, a simple yet powerful strategy using the formation of nanoparticles in situ is reported, establishing strong interfacial adhesion between various hydrogels and substrates including elastomers, plastics, and biological tissue, even under wet conditions. The strong interfacial bonding can be formed in a short time (60 s), and gradually strengthened to 902 J m-2 adhesion energy within an hour. The interfacial layer's construction involves chain entanglement and other non-covalent interactions like coordination and hydrogen bonding. Unlike the permanent bonding seen in most synthetic adhesives, these nanoparticle adhesives can be efficiently triggered for removal by acidic solutions. The simplicity of the precursor diffusion and precipitation process in creating the interfacial layer ensures broad applicability to different substrates and nanoparticle adhesives without compromising robustness. The tough adhesion provided by nanoparticles allows the hydrogel-elastomer hybrid to function as a triboelectric nanogenerator (TENG), facilitating reliable electrical signal generation and output performance due to the robust interface.

Computational design and evaluation of the mechanical and electrical behavior of a piezoelectric scaffold: a preclinical study.

Piezoelectric scaffolds have been recently developed to explore their potential to enhance the bone regeneration process using the concept of piezoelectricity, which also inherently occurs in bone. In addition to providing mechanical support during bone healing, with a suitable design, they are supposed to produce electrical signals that ought to favor the cell responses. In this study, using finite element analysis (FEA), a piezoelectric scaffold was designed with the aim of providing favorable ranges of mechanical and electrical signals when implanted in a large bone defect in a large animal model, so that it could inform future pre-clinical studies. A parametric analysis was then performed to evaluate the effect of the scaffold design parameters with regard to the piezoelectric behavior of the scaffold. The designed scaffold consisted of a porous strut-like structure with piezoelectric patches covering its free surfaces within the scaffold pores. The results showed that titanium or PCL for the scaffold and barium titanate (BT) for the piezoelectric patches are a promising material combination to generate favorable ranges of voltage, as reported in experimental studies. Furthermore, the analysis of variance showed the thickness of the piezoelectric patches to be the most influential geometrical parameter on the generation of electrical signals in the scaffold. This study shows the potential of computer tools for the optimization of scaffold designs and suggests that patches of piezoelectric material, attached to the scaffold surfaces, can deliver favorable ranges of electrical stimuli to the cells that might promote bone regeneration.

Spatiotemporal imaging and manipulation of surface plasmons

Abstract Surface plasmon polaritons (SPPs) are travelling surface waves that have shown promise for applications in nanophotonics as they provide a direct route toward photon-mediated electrical signal generation – a central paradigm for speeding up and scaling down photonic elements. SPP waves have also generated fundamental interest due to their high-field strength and sub-wavelength confinement, properties that have enabled the surface-enhanced Raman effect. Over the last decade, photoemission electron microscopy (PEEM) has emerged as a pioneering technique for imaging surface electric fields through ultrashort laser pulse mediated electron emission and has therefore become an indispensable tool for characterizing plasmonic phenomena at interfaces in a variety of materials. PEEM offers nanometer spatial resolution and femtosecond temporal resolution, allowing SPPs to be prepared, monitored, and manipulated on the nanometer-femtosecond scale. Through a brief review of recent reports, we aim to introduce PEEM-based SPP imaging and manipulation modalities and highlight their utility in the context of emerging nanoscale and quantum materials science advancements.

Rapid Propagation of Ca2+ Waves and Electrical Signals in the Liverwort Marchantia polymorpha.

In response to both biotic and abiotic stresses, vascular plants transmit long-distance Ca2+ and electrical signals from localized stress sites to distant tissues through their vasculature. Various models have been proposed for the mechanisms underlying the long-distance signaling, primarily centered around the presence of vascular bundles. We here demonstrate that the non-vascular liverwort Marchantia polymorpha possesses a mechanism for propagating Ca2+ waves and electrical signals in response to wounding. The propagation velocity of these signals was approximately 1-2 mm s-1, equivalent to that observed in vascular plants. Both Ca2+ waves and electrical signals were inhibited by La3+ as well as tetraethylammonium chloride, suggesting the crucial importance of both Ca2+ channel(s) and K+ channel(s) in wound-induced membrane depolarization as well as the subsequent long-distance signal propagation. Simultaneous recordings of Ca2+ and electrical signals indicated a tight coupling between the dynamics of these two signaling modalities. Furthermore, molecular genetic studies revealed that a GLUTAMATE RECEPTOR-LIKE (GLR) channel plays a central role in the propagation of both Ca2+ waves and electrical signals. Conversely, none of the three two-pore channels were implicated in either signal propagation. These findings shed light on the evolutionary conservation of rapid long-distance Ca2+ wave and electrical signal propagation involving GLRs in land plants, even in the absence of vascular tissue.

Кросс-секционное исследование потребления алкоголя с вредными последствиями у пациентов кардиологического профиля, госпитализированных по неотложным показаниям в многопрофильный стационар

Background. Alcohol use affects many aspects of the functioning of the cardiovascular system. It causes an increased risk of: hypertension; pathological conditions caused by disorders of generation and conduction of electrical signals in the myocardium; cardiovascular diseases such as ischaemic and haemorrhagic strokes. Aim of the study. To study the prevalence of alcohol consumption among acutely ill cardiac patients, not requiring intensive care, hospitalized in a multidisciplinary urban clinical hospital, using screening self-questionnaires (AUDIT-4) and a highly sensitive and specific marker of chronic alcohol intoxication phosphatidylethanol (PEth). Materials and Methods. Using AUDIT-4 and PEth, we studied the prevalence of alcohol use in cardiac patients with regard to their socio-demographic characteristics. Statistical analysis was performed using IBM SPSS Statistics 25.0 software. We applied descriptive statistics and logistic regression model to estimate adjusted odds ratio for socio-demographic and diagnostic cofactors associated with alcohol abuse. Study results. PEth values in peripheral blood of 0.3 µmol/l or more, indicating excessive alcohol consumption during 2-4 weeks prior to hospitalization, were noted in 8.9% of patients. At the same time, 3.0% of patients admitted the fact of alcohol consumption during the day preceding hospitalization. The presence of only one patient with a diagnosis of alcoholic cardiomyopathy is noteworthy. Negatively associated with PEth level ≥0.3 μmol/L were patients in age group ≥71 compared with patients aged 18-40 as the reference group, (AOR 0.058; CI 95% 0.009-0.379; p<0.003) and women compared with men (AOR 0.227, CI 95% 0,113-0,445; р<0,001). There was a positive association with PEth level ≥0.3 μmol/L for patients who defined their marital status as divorced/separated compared to the reference group married/married/civil partnership (AOR 2.535; CI 95% 1.218-5.276; p=0.013). A significant positive association with a PEth level ≥0.3 μmol/L (AOR 6.668; CI 95% 2.592-17.155; p<0.001) was observed in those who admitted drinking alcoholic beverages within 24 hours before hospitalization compared with the reference group who denied it. Diagnostic groups had no statistically significant associations with the outcome variable. Conclusions. Our findings support the need for brief anti-alcohol interventions by primary care physicians, especially when diagnosing alcohol-associated conditions in cardiac patients. It seems necessary to aim internists to work more carefully with diagnoses of alcohol-associated and alcohol-attributable conditions.

The role played by sensors consisting of smartphone and black box in analytical chemistry: Increase the achievability

In recent years, smartphone-based rapid detection methods have emerged and gained popularity among a wide range of researchers. Smartphone are favoured due to their integration of diverse functions such as photography, positioning, internet connectivity, and high-performance operating systems. The presence of a black box ensures the stable and improved conversion and transmission of optical and electrical signals, which is crucial for detection tasks carried out in environments where the ideal laboratory environment may not be feasible or guaranteed. The objective of this review is to elaborate on the application of chemical analysis based on the combined effect of smartphone and black box. Initially, we analyzed the design factors and fundamental functions of the black box. Subsequently, we provided a detailed description of the process involving the black box's integration with cuvettes, paper bases, and microtiter plates (MTPs) for presenting and transmitting light signals, which are then processed and calculated by the smartphone. We also presented the conversion and application of light signals generated by special reaction vessels and the generation of electrical signals at electrodes through the black box. Finally, we discussed the challenges and prospects associated with the combination of smartphone and black box assay models.

Ion channels in electrical signaling in higher plants

Electrical signals (ESs) of plants occurring under the action of various external factors play an important role in adaptation to changing environmental conditions. The generation of ESs in higher plant cells is associated with the activation of Ca2+, K+, and anion fluxes, as well as changes in the activity of plasma membrane H+-ATPase. In the present review, the molecular nature of ion channels contributing to ESs transmission in higher plants is analyzed based on the comparison of data from molecular-genetic and electrophysiological studies. Based on such characteristics of ion channels as selectivity, activation mechanism, and intracellular and tissue localization, those ion channels that meet the requirements for potential participants of ESs generation were selected from a wide variety of ion channels in higher plants. Analysis of the data of experimental studies performed on mutants with suppressed or enhanced expression of a certain channel gene revealed those channels whose activation contributes to ESs formation. The channels responsible for Ca2+ flux during ESs generation include channels of GLR family, for K+ flux - GORK, for anions - MSL. Consideration of the prospects for further studies suggests the need to combine electrophysiological and genetic approaches along with the analysis of ion concentrations in intact plants within a single study.

Electrical signalling and plant response to herbivory: A short review

ABSTRACTFor a long time, electrical signaling was neglected at the expense of signaling studies in plants being concentrated with chemical and hydraulic signals. Studies conducted in recent years have revealed that plants are capable of emitting, processing, and transmitting bioelectrical signals to regulate a wide variety of physiological functions. Many important biological and physiological phenomena are accompanied by these cellular electrical manifestations, which supports the hypothesis about the importance of bioelectricity as a fundamental ‘model’ for response the stresses environmental and for activities regeneration of these organisms. Electrical signals have also been characterized and discriminated against in genetically modified plants under stress mediated by sucking insects and/or by the application of systemic insecticides. Such results can guide future studies that aim to elucidate the factors involved in the processes of resistance to stress and plant defense, thus aiding in the development of successful strategies in integrated pest management. Therefore, this mini review includes the results of studies aimed at electrical signaling in response to biotic stress. We also demonstrated how the generation and propagation of electrical signals takes place and included a description of how these electrical potentials are measured.