The analysis of the failure causes of the mechanisms and drives of lifting, construction, road machines on the basis of gearing gears, as well as gears of the worm class, which are contact destruction of the active surfaces of gear teeth, leading to malfunctions, breakdowns, failures in the form of wear and scuffing. A cyclogram describing the mode of operation of the gear pair, taking into account the effect of maximum load on the contact endurance and on the endurance of the teeth during bending, and which is used in strength calculations of spur and helical gears, is given. The necessity of creating a method for calculating the wear of spiroid gears based on the variable loading mode and load time taking into account the loading schedule analysis of mechanisms and drives of hoisting-and-transport machines and equipment where this type of gear is used, in particular, in the drive of stop valve mechanisms, in the drive of screw horizontal conveyor, the cable-assembly mechanism of the electric loader, in the drive of the traction winch of the packing crane UK-25/9-18 for tugging packages of rail track panel, is substantiated. The developed method makes it possible, taking into account the actual operation modes of hoisting-and-transport machines, equipment and mechanisms, by experimentally obtained dependence of the wear rate of the spiroid wheel teeth on the torque values on the output shaft of the spiroid gearbox, to determine the values of wear intensity and calculate the duration of the resource of the spiroid gearbox in accordance with the established schedule of variable mechanism loading for lifting, construction and road cars.