Clague JE, Petrie PJ, Horan MA. Hypocapnia and its relation to fear of falling. Arch Phys Med Rehabil 2000;81:1485-8. Objective: To determine if hypocapnia occurs in patients with fear of falling and to explore potential causes of hypocapnia. Design: Observational study in patients who fall with and without fear of falling. Setting: Rehabilitation wards of an elderly care unit. Patients: Consecutive fallers with (n = 20) and without (n = 10) fear of falling. Main Outcome Measures: End-tidal CO2 (PETCO2) and respiratory rate (RR) responses were measured during sustained isometric muscle contraction (SIMC) (40% of maximum voluntary contraction of quadriceps for 2min) and during a 5-meter walk. Falls efficacy scale (FES) and Hospital anxiety and depression scale (HAD). Results: Patients with fear of falling had significantly higher FES and HAD scores (p <.01). During SIMC, baseline and nadir PETCO2 levels were significantly lower in patients with a fear of falling (p <.01). During the 5-meter walk, PETCO2 was lower at baseline, at nadir, and at the end of the walk in the fear of falling group than in controls (p <.01). RR was higher at nadir and end of the walk in the fear of falling group than in controls (p <.02). Conclusions: Hypocapnia may occur in patients with a fear of falling during SIMC and walking. Anxiety seems to be the main cause, but muscle weakness may contribute. Breathing or relaxation techniques and reconditioning may have a role in treating fear of falling in the rehabilitation setting. © 2000 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation
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