Ambulatory Continuous Peripheral Nerve Blocks and the Perioperative Surgical Home Brian M. Ilfeld, M.D., M.S., Matthew J. Meunier, M.D., Alex Macario, M.D., M.B.A. A continuous peripheral nerve block (CPNB) consists of a percutaneously inserted peri- neural catheter and subsequent local anesthetic administration to provide site-specific analgesia. With a portable infusion pump, a perineural local anesthetic infu- sion may be provided for patients at home. 1 An article published in this issue of A nesthesiology by Eng et al. 2 suggests that, after major elbow surgery, transferring care from the hospital to the periopera- tive surgical home in the presence of an ambulatory CPNB decreases hospitalization costs without com- promising medical outcomes. Initially, ambulatory CPNB was used solely for postoperative outpatients—patients who were never intended to be hospital- ized overnight—to supplement oral analgesics and improve pain control. 3 Publication of studies of uncontrolled series of patients dis- charged the morning after hip and tricompartment knee arthroplasty suggested that ambulatory CPNB might also shorten hospitaliza- tions for procedures in which inpatient stays were related mainly to postoperative pain. Adding to the optimism, previously published evidence had demonstrated that 2 to 3 days of CPNB provided solely within the hospital could shorten long-term rehabilitation stays by improving joint range of motion up to 6 weeks after knee arthroplasty or arthrolysis. 4,5 Subsequent randomized, controlled trials found that ambu- latory CPNB decreases the time to discharge readiness after knee and hip arthroplasty. However, these subjects were not allowed to actually leave the hospital much earlier than the control group, leaving any benefits of earlier discharge as a the- oretical possibility. 3 The one randomized, placebo-controlled “One can imagine a well- functioning acute regional service that delivers state- of-the-art outpatient anal- gesia as a component for the promise of the peri operative surgical home to be fully realized.” trial demonstrating hastening of actual discharge using ambula- tory CPNB investigated the effects on range of motion after shoulder arthroplasty only through the day after surgery. 6 Although research over the last two decades has led to speculation that ambulatory CPNB might shorten hospitalization after major orthopedic surgery, actual evidence quantifying the benefits and risks remains elusive and wor- thy of continued investigation. One can imagine a well-functioning acute regional service that delivers state-of-the-art outpatient analgesia as a component for the promise of the perioperative surgical home to be fully realized. 7 New Study Providing such evidence makes an article published in this issue of A nesthesiology by Eng et al. 2 unique and noteworthy. Instead of studying the effects of ambula- tory perineural infusion on vari- ous endpoints—as has been done previously—the authors investi- gated the effects of early discharge by providing all subjects having major elbow surgery with a continuous infraclavicular nerve block for a total of 60 h and randomized them to a control group remaining hospitalized for 3 days, and an experimental group permitted early dis- charge the day after surgery. Subjects discharged home the day after surgery had similar elbow range of motion after 2 weeks and 3 months compared with those hospitalized for at least 3 days. Similarly, there were no statistically significant differences in pain scores, opi- oid consumption, patient satisfaction, and function-related questionnaires. In addition, the cost of care for those hospi- talized only one night were lower than for patients staying three nights. Although previous research has suggested the Image: Summit Medical, Salt Lake City, Utah. Corresponding article on page XXX. Accepted for publication September 1, 2015. From the Department of Anesthesiology, University of California San Diego, San Diego, California (B.M.I); Outcomes Research Consortium, Cleveland, Ohio (B.M.I); Department of Orthopedic Surgery, University of California San Diego, San Diego, California (M.J.M); and Departments of Anesthesiology, Perioperative and Pain Medicine and Health Research and Policy, Stanford University, Palo Alto, California (A.M.). Copyright © 2015, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. All Rights Reserved. Anesthesiology 2015; 123:00-00 Anesthesiology, V 123 • No 6 December 2015 Copyright © 2015, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited. Downloaded From: http://anesthesiology.pubs.asahq.org/pdfaccess.ashx?url=/data/Journals/JASA/0/ by BRIAN ILFELD on 10/22/2015