Miao medicine is restricted by its own deficiencies and external challenges, which leads to poor prospects for development. For the problems such as the loss of medicine prescriptions and the inheritance of technology, only by recognizing its own deficiencies can it give play to its subjective initiative and solve the problems with appropriate medicine. In addition, Miao medicine is a part of the "quintessence" of China, and the understanding of Miao medicine is also the way to understand Chinese traditional culture. Miao medicine is a secret magic medicine accumulated from the long-term experience of the Miao people. The theoretical knowledge system formed in the development process includes astronomy, geography, history, herbology, science and technology and other scientific contents. Today, Miao medical technology and its culture play an important role in the survival, reproduction and development of the Miao people, and also contribute to the progress of human society. After thousands of years of tempering and inheriting, Miao traditional medicine has been recognized by domestic and foreign pharmacists, and has become a powerful national brand. While enriching traditional Chinese culture, Miao medicine also makes the national brand of "Chinese pharmaceutical" go to the world. However, Miao medicine, which is particularly theoretical and effective, gradually shows a trend of extinction. When the monogeneity meets Chinese medicine and Western medicine, it presents a phenomenon of exclusion and suppression, which is a topic worth pondering. Since industrialization, changes in human life style, accompanied by environmental damage, health diseases and ecological damage, have brought new challenges to mankind. Therefore, it is time to carry forward the Miao medical culture.[1]Through the elaboration of the traditional Miao medicine culture, You Lailin analyzed its influence on the development of Miao medicine, and pointed out that the traditional Miao medicine practice concept and the extensive planting of medicinal materials have promoted the economic development of Guizhou ethnic medicine industry.[2]Starting from Weber's "legitimacy theory", Liao Xiaoyu and Zhu Lu thought about the legitimacy value of Miao's medical culture, transplanted it to the cultural field, and constructed the legitimacy of Miao's medical culture from the aspects of theoretical logic, humanistic value and system.[3]It is not difficult to see that most of the previous research contents elaborated the positive effects of the theoretical system of Miao medicine and the transmission and inheritance of Miao medicine culture, but there was little ink on the consciousness of why Miao medicine culture was hindered and the mysterious idea of Miao medicine "witch doctor peer". "It is never too late to change the good", the development and progress of things in the learning from others at the same time need to recognize their own shortcomings, after the pool of wisdom can reach a hundred feet rod head, further realm. On the basis of previous studies, this paper focuses on the factors that hinder the development of Miao medicine, and understands the essence and indispensable of Miao medicine culture from the direction of rebellion.