Event Abstract Back to Event Space and memory: from neurons to behaviour Neil Burgess1* 1 University College London, United Kingdom Computational models and single unit recording data indicate that the neural basis of sense-of-location involves a compromise between Hippocampally mediated environmental information and Entorhinally mediated short-term path integration. In particular, the relevant environmental information appears to be the set of distances to extended geometrical features (boundaries) along specific allocentric directions, while short term path integration is supported by 'grid cells' whose firing may be generated by interference between oscillatory influences on firing in the theta band. Behavioural evidence suggests that human memory for the locations of objects is supported by these representations, in combination with egocentric ones.fMRI and neuropsychological experiments suggests that the human hippocampus supports an incidental allocentric representation of location relative to environmental boundaries, while the dorsal striatum supports representations of location relative to individual landmarks that is built up via reinforcement learning. These results are interpreted in terms of a computational model of memory and imagery for spatial scenes which includes a role for posterior parietal gain fields and the representations of head-direction found along Papez's circuit in translating enduring allocentric medial temporal representations into imaginable egocentric representations in medial parietal cortex. Conference: Bernstein Symposium 2008, Munich, Germany, 8 Oct - 10 Oct, 2008. Presentation Type: Oral Presentation Topic: All Abstracts Citation: Burgess N (2008). Space and memory: from neurons to behaviour. Front. Comput. Neurosci. Conference Abstract: Bernstein Symposium 2008. doi: 10.3389/conf.neuro.10.2008.01.021 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 13 Nov 2008; Published Online: 13 Nov 2008. * Correspondence: Neil Burgess, University College London, London, United Kingdom, n.burgess@ucl.ac.uk Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Neil Burgess Google Neil Burgess Google Scholar Neil Burgess PubMed Neil Burgess Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.