Efficacy Of Zn Research Articles

Facile one-pot hydrothermal synthesis of a zinc oxide/curcumin nanocomposite with enhanced toxic activity against breast cancer cells.

Zinc oxide/Curcumin (Zn(CUR)O) nanocomposites were prepared via hydrothermal treatment of Zn(NO3)2 in the presence of hexamethylenetetramine as a stabilizing agent and CUR as a bioactive element. Three ZnO : CUR ratios were investigated, namely 57 : 43 (Zn(CUR)O-A), 60 : 40 (Zn(CUR)O-B) and 81 : 19 (Zn(CUR)O-C), as assessed by thermogravimetric analyses, with an average hydrodynamic diameter of nanoaggregates in the range of 223 to 361 nm. The interaction of CUR with ZnO via hydroxyl and ketoenol groups (as proved by X-ray photoelectron spectroscopy analyses) was found to significantly modify the key properties of ZnO nanoparticles with the obtainment of a bilobed shape (as shown by scanning electron microscopy), and influenced the growth process of the composite nanoparticles as indicated by the varying particle sizes determined by powder X-ray diffraction. The efficacy of Zn(CUR)O as anticancer agents was evaluated on MCF-7 and MDA-MB-231 cancer cells, obtaining a synergistic activity with a cell viability depending on the CUR amount within the nanocomposite. Finally, the determination of reactive oxygen species production in the presence of Zn(CUR)O was used as a preliminary evaluation of the mechanism of action of the nanocomposites.

Efficacy of Zn, Fe and Mg Nano Scale and Bulk Plant Nutrient Foliar Sprays in Biochemical Changes of Blackgram Genotypes under YMV Tolerance

Evidence-based synergistic effects of Nanoscale materials, which size typically falls below 100 nm, exhibit novel chemical, physical and biological properties which are different from their bulk counterparts. Here, we report for the first time comparision of nanoscale zinc oxide (n-ZnO), magnesium oxide (n-MgO), and iron oxide (n-FeO) with their respective bulk concentrations on biochemical variability of blackgram genotypes under yellow mosaic virus condition. Oxides of nano scale Zn, Mg and Fe materials were prepared by using a modified sol-gel method. Characterization was performed by using X- ray diffraction (XRD), Dynamic Light Scattering (DLS), Scanning Electron Microscopy (SEM) Analysis and High- Resolution Transmission Electron Microscopy (HRTEM). Average sizes of ZnO, MgO and FeO (78.8, 60.8 and 12.4 nm respectively) and potentials (-36.7,-33.0 and -18.0 mV respectively). A field study was conducted during summer 2018 in split-plot design with two blackgram genotypes as main treatments (TBG-104 and LBG-623) and nine sub treatments (Control, ZnSO4 @ 0.2 %, n-ZnO @ 200ppm, MgSO4 @ 0.2 %, n- MgO @ 100ppm, FeSO4 @ 0.2%, n- FeO @ 200ppm, ZnSO4 @ 0.2 % + MgSO4 @ 0.2 % + FeSO4 @ 0.2 %, n-ZnO @ 200ppm + n- MgO @ 100ppm + n- FeO @ 200ppm) as foliar sprays with three replications. YMV infection was observed at 25 DAS. The foliar treatmental sprays were imposed at 30 and 50 DAS.
 Results of the field study revealed that combined application of nanoscale treatmental spray ZnO @ 200 ppm + MgO @ 100 ppm + FeO @ 200 ppm resulted higher YMV tolerance interms of high chlorophyll content, total phenols, total proteins and lower total soluble sugars, followed by combined bulk treatmental spray ZnSO4 @ 0.2% + MgSO4 @ 0.2% + FeSO4 @ 0.2% and nano scale Magnesium Oxide @ 100 ppm. Here we concluded that either of these three foliar sprays can be recommended to blackgram crop prone to YMV condition to sustain plant growth and final yields. But, there should be study on the impact of different shape, size of nano particles on plant system and the promotery effects of nano scale Oxides of Zn, Mg and Fe particles at cellular level and transport mechanism in plant system needs to be understood.

Zinc alleviates cadmium induced heavy metal stress by stimulating antioxidative defense in soybean [Glycine max (L.) Merr.] crop

The interaction between cadmium- a toxic metal and zinc- an essential micronutrient was investigated in influencing the activity of various antioxidant enzymes and related metabolites in soybean [Glycine max (L.) Merr.]. Higher levels of cadmium (Cd) stimulate the activity of potential enzymes like ascorbate peroxidase (APX), superoxide dismutase (SOD) accompanied by the buildup of non-enzymatic metabolites, hydrogen peroxide (H2O2), malondialdehyde (MDA) and proline due to rise in oxidative stress of plants. Also, the reduced activity of catalase (CAT), glutathione reductase (GR) and ascorbic acid (AsA) content was based upon Cd treatment levels. Application of zinc (Zn) combination enhances the activity of enzymes like APX, GR, CAT and SOD in Cd treatments, also confirmed with the depleted levels of H2O2. Zn alone treatment had no significant effect on the activity of such enzymes indicating the toxicity owing to Cd treatments only. The accumulation behavior of other non-enzymatic metabolites like MDA, proline and ascorbic acid also get reversed with metal combination treatment. Moreover, the efficacy of Zn was more when applied in higher concentrations with low Cd. Thus, Zn plays a key role in plants to counter heavy metal stress by elevating antioxidative defense with higher activity of enzymes and reduced levels of non-enzymatic metabolites, and efficacy of Zn in combination is dose dependent.

PREPARATION AND PROPERTY STUDIES OF Zn3P2/CALCIUM ALGINATE

Zn 3 P 2 is an acute and effective rodenticide used widely to protect grains in stores and domestically to kill rodents. This study aims to postpone the time of poisoning symptoms after eating Zn 3 P 2 and improve the effect of killing rodents. Zn 3 P 2/calcium alginate ( Zn 3 P 2/ CA ) was synthesized through the reaction of sodium alginate and calcium chloride by the reversed-phase microemulsion method and then loaded with Zn 3 P 2 technical. It was characterized by X-ray diffractometer, laser particle size analyzer, scanning electron microscope (SEM) and transmission electron microscopy (TEM). The drug loading capacity, slow-controlled release performances and toxic effects were also investigated. The results showed that Zn 3 P 2/ CA was spherical, average particle size was 353.9 nm, and particle dispersion index (PDI) was 0.195. The mass ratios of calcium alginate and Zn 3 P 2 technical ( CA / Zn 3 P 2) had significant impacts to drug loading capacity and slow-controlled release performances of Zn 3 P 2/ CA . The palatability and efficacy of Zn 3 P 2/ CA were significantly improved and enhanced compared with Zn 3 P 2 technical. The results showed that Zn 3 P 2/ CA presented high loading efficiency, commendable sustained-release performance and good environmental compatibility, and this delivery carrier may be extended to other slow-controlled release and high-efficient pesticide formulation in future.

Biosorption of Zn (II) onto the Surface of Non-living Biomasses: A Comparative Study of Adsorbent Particle Size and Removal Capacity of Three Different Biomasses

Present research has delineated the biosorption potential of three different nonliving biomasses namely eucalyptus bark saw dust, mango bark saw dust, and pineapple fruit peel with respect to Zn (II) ion removal from liquid phase through batch experiments. The efficacy of Zn (II) ion biosorption onto surface of biosorbents was judged and correlated with biosorbent particle size, surface chemistry, and surface texture. Maximum metal ion uptake capacity, percentage removal, and minimum equilibrium concentration as 1.688 mg/g, 84.4%, and 1.56 mg/l, respectively, was obtained using eucalyptus bark saw dust mediated biosorption followed by mango bark saw dust as 1.028 mg/g, 51.4%, and 4.867 mg/l and pineapple fruit peel as 0.45 mg/g, 22.9%, and 7.71 mg/l, respectively, at a particle size of 0.5 mm. Additionally, present investigation also proved that biosorption efficiency and metal ion interaction with adsorbent surface also depends upon presence of functional groups involved in metal ion adsorption and surface porosity.