A field trial was conducted to evaluate the efficacy of soil amendments with organic compost and synthetic (chemical fertilizers) on suppressing the pathogen of chickpea wilt, Fusariumoxysporumf.sp. ceceris. In the experiment four levels of a mixed poultry-plant compost (7.5, 15, 22.5, and 30 t/ha) and four levels of the compound fertilizer, NPK, (100, 200, 300, and 400 kg/ha) were evaluated and compared with untreated control. Results revealed that there were significant effects of organic compost on decreasing disease incidence and severity at the level of 30 t/ha. The use of high levels of NPK (300 and 400 kg/ha) were also effective in lowering the disease. The efficiency of organic matter on the level of 30 t/ha was as much as 55.61% followed by using synthetic fertilizer at the level of 400 kg/ha (44.57%). The uses of the previous treatments were also effective to gain higher yield of chickpea. The highest yield was obtained when the soil amended with organic matter at the levels of 30 t/ha and 22.5 t/ha followed by using of NPK at 400 kg/ha.