Efficacy Of Cryolipolysis Research Articles

Predicting the subcutaneous temperature in cryolipolysis using deep operator networks

Accurate monitoring of subcutaneous temperature is crucial for the safety and efficacy of cryolipolysis. However, existing measurement and simulation methods often require trade-offs between accuracy, depth, and computational efficiency. This study introduces a novel deep learning architecture, ConvD-DeepONet, specifically designed to predict subcutaneous temperature fields with both high accuracy and efficiency. The model effectively captures spatial information and produces multi-dimensional output, owing to the innovative integration of convolutional layers and the decoder network. An average absolute error (MAE) of 0.0038 ℃ and a root mean square error (RMSE) of 0.0083 ℃ are achieved, resulting in over a 50 % reduction compared to the baseline models. Moreover, each prediction is completed in just 5.9 ms, rendering it 120 times faster than traditional finite element method simulations. These results indicate that ConvD-DeepONet is a promising tool for real-time subcutaneous temperature prediction, with the potential to enhance the safety and efficacy of cryolipolysis.

Cryolipolysis: Clinical Best Practices and Other Nonclinical Considerations.

Cryolipolysis is a nonsurgical body contouring procedure that involves cooling of fat cells to induce lipolysis while sparing surrounding structures. Plastic surgery practices are increasingly incorporating noninvasive aesthetic procedures (eg, cryolipolysis, fillers, radiofrequency, ultrasound) to offer their patients a wider range of aesthetic treatment options. Here, we report insights from 8 plastic surgeons with regard to cryolipolysis best practices from a clinical perspective and the impact of integrating this noninvasive body contouring procedure into a plastic surgery practice. The authors prefer cryolipolysis over liposuction for patients who are not amenable to surgery or those who desire to avoid downtime, also taking into consideration body mass index, skin laxity, comorbidities, and risk of contour irregularities. Patient counseling is critical for setting realistic expectations regarding outcomes and should focus on the efficacy of cryolipolysis, individual variability in results, potential side effects, time course of treatment response, and the need for multiple treatment cycles. Strategies for reaching new patients and expanding services among current cryolipolysis patients are discussed.

Efficacy of cryolipolysis for fat reduction and body contouring: A systematic review and meta-analysis

Efficacy of cryolipolysis for fat reduction and body contouring: A systematic review and meta-analysis

Cryolipolysis for Targeted Fat Reduction and Improved Appearance of the Enlarged Male Breast.

Pseudogynecomastia refers to benign male breast enlargement due to excess subareolar fat. Standard treatment is surgical excision under general anesthesia, liposuction, or a combination of both. The safety and efficacy of cryolipolysis was investigated for nonsurgical treatment of pseudogynecomastia. Enrollment consisted of 21 males with pseudogynecomastia. Subjects received a first treatment consisting of a 60-minute cryolipolysis cycle, followed by a two-minute massage, and a second 60-minute cycle with 50% treatment area overlap. At 60 days of follow-up, subjects received a second 60-minute treatment. Safety was evaluated by monitoring side effects and adverse events. Efficacy was assessed by ultrasound, clinical photographs, and subject surveys. Surveys revealed that 95% of subjects reported improved visual appearance and 89% reported reduced embarrassment associated with pseudogynecomastia. Ultrasound showed mean fat layer reduction of 1.6 ± 1.2 mm. Blinded reviewers correctly identified 82% of baseline photographs. Side effects included mild discomfort during treatment and transient paresthesia and tenderness. One case of paradoxical hyperplasia (PH) occurred but likelihood of PH in the male breast is not believed to be greater than in any other treatment area. This study demonstrated feasibility of cryolipolysis for safe, effective, and well-tolerated nonsurgical treatment of pseudogynecomastia.

Commentary on: The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature.

I commend the authors on their thorough review of cryotherapy for noninvasive localized subcutaneous fat reduction.1 Data from almost 1500 subjects across multiple body sites demonstrate that, due to its intrinsic cold-sensitivity, lipid-rich subcutaneous tissue can be preferentially targeted without damage to surrounding water-rich structures. Yet, despite all of the evidence regarding the safety and efficacy of this modality, the underlying mechanisms by which its clinical effects occur have yet to be completely elucidated. Manstein et al2 evaluated previously treated (frozen, then thawed) pig lard, providing the first evidence that …

The Safety and Efficacy of Cryolipolysis: A Systematic Review of Available Literature.

In the past decade, the practice of body contouring using cryolipolysis has increased tremendously. While numerous anecdotal reports extol the efficacy of this product, the majority of these studies are small, retrospective case-series that lack control groups. The authors aim to systematically review available literature to better illustrate the efficacy and safety of this new procedure. A systematic literature review performed using MEDLINE, Embase, PubMed, and Cochrane databases identified all published studies evaluating cryolipolysis for body contouring. A total of 34 articles up to February 2015 were identified. Nineteen articles matched the selection criteria and were included in the analysis. Sixteen were evaluated in the final analysis. A total of 1445 patients had reportable data for analysis of the safety profile. Twelve patients (0.82%) reported complications with the most common being diminished sensation lasting greater than 4 weeks. An aggregate total of 295 patients had objective data for evaluation of tissue reduction. The mean time from procedure to objective outcome evaluation was 3.83 months. The mean reduction of subcutaneous tissue was 19.55% with respect to a designated control site. Selective cryolipolysis appears, at short-term follow-up, to reliably decrease subcutaneous tissue deposits. Reported complications are uncommon and appear to resolve without intervention. Future studies should aim to optimize patient selection and treatment characteristics while obtaining long-term follow-up data.