Effects Of Variability Research Articles

The Effectiveness of Using Motion Graphics in Acquiring English Vocabulary among Second-Grade Intermediate Students

This study aimed to determine the effectiveness of using motion graphics in teaching a unit of the English language course for the second intermediate grade in acquiring vocabulary among second-grade intermediate students. The study used the English vocabulary test as an instrument to collect data and measure the effectiveness of the independent variable of the study. The test was performed twice, before and after the treatment was applied to the groups. The study used a quasi-experimental design. The study population was selected from one of the female intermediate schools in Unayzah Governorate in Al Qassim region. The study sample consisted of (54) second-grade intermediate Female students aged between (14-15) years, assigned randomly as experimental and control groups. The sample was divided into two groups, (27) students in each. The study concluded that there are statistically significant differences between the average scores of the experimental group students and the scores of the control group students in the results of the vocabulary acquisition post-test in favor of the experimental group. The study recommended using a variety of instructional strategies to meet the diverse needs and preferences of learners as well as ensure that the instructional materials and resources are accessible to all students, including those with diverse learning needs and backgrounds.

Cultural and Spiritual Adaptations to Extreme Weather Events of Ethnic Farming Communities of the Three Watersheds Situated at Different Altitudinal Locations along Agno River Basin, Benguet and Pangasinan, Philippines

Ethnic farming communities in Agno River Basin face climate stressors that threaten their agricultural production. This paper investigated and assessed the cultural/spiritual adaptations to climate variabilities and extremes of ethnic farming communities in Agno River Basin, Philippines. How the presence of these cultural/spiritual practices moderate or mitigate the effects of climate variabilities and extremes were likewise investigated. The climate-related hazards considered in this study which are pronounced in the river basin are prolonged and extreme rainfall intensity, typhoons and extreme winds, drought, flood and occurrence of pests and diseases. These hazards are becoming more frequent and intense resulting to limited agricultural production. This paper considered only the sectors of agriculture/socioeconomic, water and health. The descriptive method employed in this study was based on the works of Oppenheimer et al (2014); Saroar, Routray and Leal Filho (2015) and Brooks and Adgers(undated). The data-gathering activities were household survey using pre-tested questionnaires, focused group discussions and key informant interviews. The ethnic affiliations of the farming communities were I-Karao, Ibaloi, Kankanaey and Kalanguya tribes. Secondary data on changing rainfall and erratic temperature characteristics were consistent with the general perception of the ethnic farming communities. Cultural/ spiritual traditions of Ethnic farming communities in the Agno River Basin form part of their adaptations to climate extremes and variabilities. The greatest number of rituals and activities (5) such as childless couples raising plant materials, burning of rice straws and Alay, Leppas, Maepdesan, and Ibkas or maboteng. are dedicated to ensuring a good harvest. Canyao, Libot, and Begnas are undertaken to prevent the occurrence of hazards. On the other hand, Ubob, Bayanihan, and Sakdo are adaptations to mitigate the impact of climate extremes and variabilities. Both Canyao and Leppas are also thanksgiving activities while Tagainep or dream interpretation serves as a coping mechanism.

A Detailed Examination of Türkiye's Projected Precipitation and Growth Season Trends under Climate Change Condition

This study presents a comprehensive analysis of Türkiye's changing precipitation patterns and growing season dynamics in the context of global warming, utilizing the Coupled Model Intercomparison Project Phase 5 (CMIP5) and various Representative Concentration Pathway (RCP) scenarios. In light of global warming, this study provides a thorough analysis of Türkiye's evolving precipitation patterns and growing season dynamics using multiple RCP scenarios and CMIP5. The research aims to fill a crucial gap in climate research by combining historical data and future projections to assess Türkiye's precipitation path under different greenhouse gas emission scenarios. The study employs linear regression for trend analysis and uses data from the Climate Change Knowledge Portal (CCKP), with a focus on precipitation data from 1986 to 2100. According to various RCP scenarios, this study’s findings show a considerable variation in precipitation trends over the 21st century. The RCP 8.5 scenario predicts a significant decrease in precipitation, which would present difficulties for the management of water resources and agricultural productivity. In contrast, the least severe RCP 2.6 pathway shows a fairly stable pattern of precipitation. Complex seasonal hydrological responses to climate change are revealed by monthly precipitation analysis; RCP8.5 predicts an increase in the frequency of periods of drought and heavy precipitation events. The impact of these changes in precipitation on Türkiye's agricultural growing seasons was further investigated in this study. In high-emission scenarios, there was an initial tendency towards longer growing seasons, which were subsequently followed by shorter ones. This suggests that although global warming might initially result in an extended growing season, it might ultimately cause a reduction in it, particularly in situations where mitigation efforts are minimal. The need for adaptable strategies that can respond to long-term climate trends as well as seasonal variability was highlighted by this research. It draws attention to the fact that to mitigate the effects of climate variability, informed policy decisions and integrated resource management are essential. The results highlight the need for quick action to lower the risks associated with water and highlight the potential advantages of intensive mitigation efforts in stabilizing and extending growing seasons.

Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigs.

Transdermal delivery of peptide drugs is almost impossible with conventional penetration enhancers because of epidermal barrier function. Microneedle (MN) patches can bypass the epidermal barrier and have been developed for trans- and intradermal delivery of peptide drugs and vaccines. However, dissolving MN patches are limited by low drug loading capacities due to their small size and admixture of drug and water-soluble excipients. Furthermore, few in vivo pharmacokinetic studies, especially in large animals such as pigs, have been performed to assess post-application systemic drug exposure. Here, we developed a dissolving MN patch with pure liraglutide at the needle tips. The MN patch could load up to 2.21 ± 0.14mg of liraglutide in a patch size of 0.9 cm2, which was nearly two orders of magnitude higher than that obtained with conventional MN patches of the same size. Raman imaging confirmed that liraglutide was localized at the MN tips. The MN had sufficient mechanical strength to penetrate the epidermis and could deliver up to 0.93 ± 0.04mg of liraglutide into skin with a dosing variability of less than 6.8%. The MN patch delivery enabled faster absorption of liraglutide than that provided by subcutaneous (S.C.) injection, and achieved relative bioavailability of 69.8% and 46.3% compared to S.C. injection in rats and minipigs, respectively. The MN patch also exhibited similar patterns of anti-hyperglycemic effect in diabetic rats and individual variability in pharmacokinetic parameters as S.C. injection. The liraglutide MN application was well tolerated; no skin irritation was observed in minipigs except for mild erythema occurring within 4h after once daily administration for 7days at the same site. Our preclinical study suggests that MN patch with pure drug needle tips might offer a safe and effective alternative to S.C. injection for administration of liraglutide.

Analysis of intervarietal soybean hybrids at the initial breeding stages

The results of the study of recombinant soybean hybrids in terms of the degree of heterosis effect, phenotypic dominance and transgressive variability in economically valuable traits with the subsequent selection of the most promising hybrid combinations are presented. The study was conducted from 2018 to 2022 in the laboratory of soybean breeding in the conditions of the steppe zone of the Primorsky Territory. Of the ten hybrid combinations obtained, the maximum effect of heterosis in the first generation was observed in the combinations Primorskaya 1385 × Kofu, Primorskaya 1385 × Dong nong 690, Hei He 38 × Taifun. Phenotypic overdominance of inheritance of indicators (from 1.6 to 76.7) was recorded in all hybrids. Transgressive variability of intervarietal soybean hybrids in the second and third generations varied by combination and generation. High values of the degree of transgression in the third generation were observed in the combinations Primorskaya 1385 × Kofu and Hei He 38 × Talppod-Fisk, in terms of the number of seeds per plant – Primorskaya 1385 × Taifun and Kofu × Taifun, in terms of seed weight per plant – Dong nong 690 × Taifun and Hei He 38 × Taifun. A decrease in the frequency of transgression of hybrids by the third generation was found. The highest values of the degree and frequency of transgression in plant height were observed in the hybrid combinations Hei He 38 × Taifun and Hei He 38 × Talppod-Fisk. Based on the results of the study of the promising soybean genotypes, recombinant hybrids with high productivity and 1000-seed weight in the combinations Kyoto × Dong nong 690 and Monsoon × Taifun were isolated. The hybrids tested had different ripeness groups. Not always the manifestation of high effect of heterosis and transgressive variability in the first – third generations serves as a guarantee of further obtaining samples with high economically valuable indicators.

The Influence of Explosive and Rock Mass Properties on Blast Damage in a Single-Hole Blasting

In rock blasting for mining production, stress waves play a major role in rock fracturing, along with explosive gases. Better energy distribution improves fragmentation and safety, lowers production costs, increases productivity, and controls ore losses and dilution. Blast outcomes vary significantly depending on the choice of the explosive and the properties of the rock mass encountered. This study analyzes the effects of rock mass and explosive properties on blast outcomes via numerical simulation using data from the case study, and later validates the simulation results from the field blast fragmentation. The findings suggest that, for a given set of rock properties, the choice of explosive has a major influence on the resulting fragmentation. Strong explosives (high VOD and detonation pressure) favor large fracture extents in hard rocks, while weaker explosives offer a better distribution of explosive energy and fractures. The presence of rock structures such as rock contacts and joints influences the propagation of stress waves and fractures depending on the structures’ material properties, the intensity and orientations, and the direction and strength of the stress wave. When the stress wave encounters a contact depending on its direction, it is enhanced when traveling from soft to hard and attenuates in the opposite direction. The ability of the stress wave to cause fracturing on the opposite side of the contact depends on the intensity of the transmitted wave and the strength of the rock. Transmitted wave intensity is a function of the strength of the incident wave and the impedance difference between the interface materials. The presence of joints in the rock mass affects the propagation of the stress wave, mainly depending on the infill material properties and the angle at which the stress wave approaches the joint. Less compressible, higher stiffness joints transmit more energy. More energy is also transmitted in the areas where the stress wave hits the joint perpendicularly. Joints parallel to the free face offer additional fracturing on the opposite side of the joint. Other parameters, such as the joint width, continuity, fracture frequency, and the distance from the charge, enhance the effects. To achieve effective fragmentation, the blast design should mitigate the effect of variability in the rock mass via explosive selection and pattern design to ensure adequate energy distribution within the limits of geometric design.

Impact of Variability on Novel Transistor Configurations in Adder Circuits at 7nm FinFET Technology

This research work focuses on implementation of the FinFET-based complementary metal-oxide-semiconductor (CMOS) Full Adder circuits for different transistor configurations using ASAP7 FinFET model. First, this work examines FinFET-based AND-OR-invert (AOI) gates using different topologies, and second, a FinFET-based CMOS Full Adder circuit at the 7[Formula: see text]nm technology node is analyzed with respect to its process, voltage and temperature (PVT) variability effect measured in terms of the normalized standard deviation of different performance metrics. The comparison is made between conventional (CFFA1) and proposed (FFA2, FFA3, FFA4, FFA5, FFA6, FFA7 and FFA8) FinFET-based CMOS full adder circuits. The aim is to determine the optimal design configuration of the FinFET full adder circuit with the minimum impact of PVT variability. On examining the power delay product (PDP) variability, it is found that variations in FFA2, FFA3, FFA4, FFA5, FFA6, FFA7 and FFA8 are significantly lower than CFFA1 by 6.30%, 4.68%, 10.30%, 65.48%, 68.05%, 65.61% and 17.20%, respectively. Among all the proposed configurations, normalized standard deviation [Formula: see text] for the PDP metric is lowest in FFA6, followed by FFA7, FFA5, FFA8, FFA4, FFA2 and FFA3. The normalized standard deviation [Formula: see text] for power dissipation, however, is lowest in FFA8. In addition, a layout comparison analysis of conventional and proposed full adder circuits reveals that FFA7 has the least area, followed by FFA8, FFA6, FFA5, FFA3, FFA4, FFA2 and CFFA1. The area of FFA2, FFA3, FFA4, FFA5 and FFA6 has decreased by 3.29%, 3.51%, 3.50%, 5.14% and 5.52%, while FFA7 and FFA8 have experienced a decrease in area by 13.87% and 14.36%, respectively, as compared to conventional CFFA1. The proposed layout of FinFET-based CMOS Full Adders can be directly transferred into the foundry’s production line for manufacturing purposes. The overall investigation led us to conclude that FFA8 is the most efficient of all due to the lowest power variation, lower delay variation and lower PDP variation, moreover it has a reduced layout area among all the discussed designs. However, there is a tradeoff in terms of penalty in nominal power, propagation delay and PDP in the proposed topologies.

The effects of mnemonic variability and spacing on memory over multiple timescales

The memory benefit that arises from distributing learning over time rather than in consecutive sessions is one of the most robust effects in cognitive psychology. While prior work has mainly focused on repeated exposures to the same information, in the real world, mnemonic content is dynamic, with some pieces of information staying stable while others vary. Thus, open questions remain about the efficacy of the spacing effect in the face of variability in the mnemonic content. Here, in two experiments, we investigated the contributions of mnemonic variability and the timescale of spacing intervals, ranging from seconds to days, to long-term memory. For item memory, both mnemonic variability and spacing intervals were beneficial for memory; however, mnemonic variability was greater at shorter spacing intervals. In contrast, for associative memory, repetition rather than mnemonic variability was beneficial for memory, and spacing benefits only emerged in the absence of mnemonic variability. These results highlight a critical role for mnemonic variability and the timescale of spacing intervals in the spacing effect, bringing this classic memory paradigm into more ecologically valid contexts.

Impact of talker variability on language development in two-year-olds.

This research investigated the impact of the number of talkers with whom children engage in daily conversation on their language development. Two surveys were conducted in 2020, targeting two-year-olds growing up in Japanese monolingual families. Caregivers reported the number of talkers in three age groups and children's productive vocabulary via questionnaires. The results demonstrated significant effects of variability in talkers in fifth grade or above in Study 1 (N = 50; male = 23; r = .372) and in adult talkers in Study 2 (N = 175; non-nursery going; male = 76; r = .184) on children's vocabulary development, after controlling for language exposure time and demographic variables. Possible mediating factors are discussed. This research extends previous findings from immigrant bilingual children to monolingual speakers in Japan, suggesting the potential contribution of available talkers other than caregivers in conversational environments.

Factors Affecting Micro Small and Medium Enterprises Taxpayer Compliance at Cilegon Pratama Tax Office

Factors Affecting Micro small and Medium Enterprises Taxpayer Compliance at Cilegon Tax Office. Ainaya Nurulina Nafaril. Master of Accounting Study Programme. The low level of taxpayer compliance in reporting tax obligations greatly affects state revenue. The decreasing level of taxpayer compliance is a bad impact on the state because taxes are an important fund for the state. This study aims to determine the factors that influence Micro small and Medium Enterprises taxpayer compliance at KPP Cilegon. The research method used is the survey method. The results showed that the variables of Taxpayer Understanding, Service Quality and Tax Sanctions had a positive and significant influence on Taxpayer Compliance. While the perceived effectiveness of the tax system variable has a positive and insignificant effect on taxpayer compliance. Therefore, to increase taxpayer compliance, the government needs to make efforts such as the government should increase Micro small and Medium Enterprises taxpayers' understanding of tax regulations through various education and socialisation programs through various media such as seminars, training, and social media. The government needs to improve the quality of services to Micro small and Medium Enterprises taxpayers, both in terms of speed, accuracy and ease of access. The government must be careful in applying tax sanctions so as not to have a negative impact on the economy. The results of this study are expected to provide information to policy makers as a basis for consideration to improve taxpayer compliance.

Behavioural consequences of intraspecific variability in a mate recognition signal.

Mate recognition is paramount for sexually reproducing animals, and many insects rely on cuticular hydrocarbons (CHCs) for close-range sexual communication. To ensure reliable mate recognition, intraspecific sex pheromone variability should be low. However, CHCs can be influenced by several factors, with the resulting variability potentially impacting sexual communication. While intraspecific CHC variability is a common phenomenon, the consequences thereof for mate recognition remain largely unknown. We investigated the effect of CHC variability on male responses in a parasitoid wasp showing a clear-cut within-population CHC polymorphism (three distinct female chemotypes, one thereof similar to male profiles). Males clearly discriminated between female and male CHCs, but not between female chemotypes in no-choice assays. When given a choice, a preference hierarchy emerged. Interestingly, the most attractive chemotype was the one most similar to male profiles. Mixtures of female CHCs were as attractive as chemotype-pure ones, while a female-male mixture negatively impacted male responses, indicating assessment of the entire, complex CHC profile composition. Our study reveals that the evaluation of CHC profiles can be strict towards 'undesirable' features, but simultaneously tolerant enough to cover a range of variants. This reconciles reliable mate recognition with naturally occurring variability.

Disentangling influences of driving forces on intra-annual variability in sediment discharge in karst watersheds

The intra-annual variability in sediment discharge was considerably influenced by the climate variability and vegetation dynamics. Because of the coupled or relationships between climatic and vegetation variables, it is still challenging to decouple the direct and indirect effects of climate variability and vegetation dynamics on hydrological and sediment transport processes. The purpose of this study is to decouple influences of individual driving force on intra-annual distribution of sediment discharge during 2003–2017 using the partial least squares structural equation model (PLS-SEM) method in four typical karst watersheds of Southwest China. The coefficient of variation (Cv), Completely regulation coefficient (Cr), Lorenz asymmetry coefficient and Gini coefficient were used to represent the intra-annual sediment discharge variability. Results showed that the monthly sediment discharge (190 % < Cv < 353 %) exhibited greater variability than its potential affecting factors (18 % < Cv < 101 %). From the PLS-SEM analysis, the water discharge, climate, and vegetation together explain 57 %–75 %, 64 %–79 %, and 53 %–80 % of the total variance in Cv, Cr, and Gini coefficient, respectively. Specifically, water discharge exerts the largest influence on sediment discharge variability (0.65 ≤ direct effect ≤0.97, P < 0.05), while vegetation dynamic mainly indirectly affects sediment discharge variability (−0.88 ≤ indirect effect ≤ −0.01) through influencing water discharge. The climate factors also principally indirectly affect the sediment discharge variability (−0.47 ≤ indirect effect ≤0.19) by affecting water discharge and vegetation. The PLS-SEM can effectively reveal the driving force and influencing mechanism of intra-annual sediment discharge changes, and provide an important reference for regional soil and water resources management in karst watersheds. Future studies can decouple the influences of the extreme climate, unique lithology, discontinuous soil, heterogeneous landscape, and special geomorphology on spatial variability in sediment discharge across different karst watersheds.

Effects of soil spatial variability on the seismic response of multi-span simply-supported highway bridges

Effects of soil spatial variability on the seismic response of multi-span simply-supported highway bridges

Distinctive Patterns of Water Level Change in Swedish Lakes Driven by Climate and Human Regulation

AbstractDespite having approximately 100,000 lakes, Sweden has limited continuous gauged lake water level data. Although satellite radar altimetry (RA) has emerged as a popular alternative to measure water levels in inland water bodies, it has not yet been used to understand the large‐scale changes in Swedish lakes. Here, we quantify the changes in water levels in 144 lakes using RA data and in situ gauged measurements to examine the effects of flow regulation and hydroclimatic variability. We use data from several RA missions, including ERS‐2, ENVISAT, JASON‐1,2,3, SARAL, and Sentinel‐3A/B. We found that during 1995–2022, around 52% of the lakes exhibited an increasing trend and 43% a decreasing trend. Most lakes exhibiting an increasing trend were in the north of Sweden, while most lakes showing a decreasing trend were in the south. Regarding the potential effects of regulation, we found that unregulated lakes had smaller trends in water level and dynamic storage than regulated ones. While the seasonal patterns of water levels in the lakes in the north are similar in regulated and unregulated lakes, in the south, they differ substantially. This study highlights the need to continuously monitor lake water levels for adaptation strategies in the face of climate change and understand the downstream effects of water regulatory schemes.

Evaluating the Effects of Reducing Voltage Margins for Energy-Efficient Operation of MPSoCs

Voltage margins, or guardbands, are imposed on DVFS systems to account for process, voltage, and temperature variability effects. While necessary to assure correctness, guardbands reduce energy efficiency, a crucial requirement for embedded systems. The literature shows that error detection techniques can be used to maintain the system’s reliability while reducing or eliminating the guardbands. This letter assesses the practically available margins of a commercial RISC-V MPSoC while violating its guardband limits. The primary motivation of this work is to support the development of an efficient system leveraging the redundancy of multicore architectures for an error detection and correction scheme capable of mitigating the errors caused by aggressive voltage margin reduction. For an equivalent performance, we achieved up to 27% energy reduction while violating the manufacturer’s defined guardband, leaving reasonable energy margins for further development.

The Role of the Intraspecific Variability of Hydraulic Traits for Modeling the Plant Water Use in Different European Forest Ecosystems

AbstractThe drought resilience of forest ecosystems is generally believed to depend on the dominant tree species' hydraulic traits. These traits define the maximum water transport capacity and the degree of vulnerability to hydraulic failure of a tree species. This work evaluates the effect of the intraspecific variability of hydraulic traits on the simulated tree water use in the Community Land Model (CLM, version 5.0). We selected two contrasting broadleaved tree species and performed a series of numerical experiments by modifying the parameters of the plant vulnerability curve and the maximum xylem hydraulic conductance accounting for the variability within each species. Our prescribed parameter sets represent vulnerable and resistant tree responses to the water deficit. At sites with an ample water supply, the resistant configuration simulates reduced water stress and increased transpiration compared to the vulnerable configuration. Meanwhile, the model results are counter‐intuitive at temporarily dry sites when water availability is the limiting factor. The numerical experiments demonstrate the emergent role of the maximum xylem conductance as a modulator of the plant water use strategy and the simulated transpiration within the model. Using the default value for maximum xylem conductance, the model tends to overestimate the early summer transpiration at drier sites, forcing the vegetation to experience unrealistic water stress later in the year. Our findings suggest that the parameterization of maximum xylem conductance is an important yet unresolved problem in the CLM and similar land surface models.

Effect of hydrological variability on suspended sediment load at a river junction: a case study

Abstract Confluences act as crucial intersection in a fluvial system as they regulate the flow, sediment, and geomorphological stability. Two of the natural occurrences that have an effect on hydro-morphological processes that characterize the channel are sediment movement and stream discharge. However, assessments of suspended sediment distribution patterns across channel confluences and functions of tributaries on sediment transfer in downstream streams are still inadequately explored. To fulfil this, a year-long field investigation was conducted around river confluence at various time scales during the hydrological season. The bathymetry of the confluence was performed using digital echo-sounding equipment, electro-magnetic current meter, and differential global positioning equipment. This study uses in situ measurement and empirical techniques to quantify the spatiotemporal distribution of suspended sediment particles. Furthermore, Yang's formula was used to analyze the sediment concentration, and several statistical standards were employed to establish a differentiation between predicted and observed data. The results illustrated that a good agreement has been achieved among the calculated and measured statistics based on the correlation coefficient value. According to the findings, 8% fewer errors in the quantification of suspended sediment were induced in the tributary than in the main river because of the very low flow of the tributary. The present ramifications can help increase our database and understanding of the dynamics of major river confluences.

Investigating critical brain area for EEG-based binocular color fusion and rivalry with EEGNet.

Binocular color fusion and rivalry are two specific phenomena in binocular vision, which could be used as experimental tools to study how the brain processes conflicting information. There is a lack of objective evaluation indexes to distinguish the fusion or rivalry for dichoptic color. This paper introduced EEGNet to construct an EEG-based model for binocular color fusion and rivalry classification. We developed an EEG dataset from 10 subjects. By dividing the EEG data from five different brain areas to train the corresponding models, experimental results showed that: (1) the brain area represented by the back area had a large difference on EEG signals, the accuracy of model reached the highest of 81.98%, and more channels decreased the model performance; (2) there was a large effect of inter-subject variability, and the EEG-based recognition is still a very challenge across subjects; and (3) the statistics of EEG data are relatively stationary at different time for the same individual, the EEG-based recognition is highly reproducible for an individual. The critical channels for EEG-based binocular color fusion and rivalry could be meaningful for developing the brain computer interfaces (BCIs) based on color-related visual evoked potential (CVEP).

Time in Range, Time in Tight Range, and Average Glucose Relationships Are Modulated by Glycemic Variability: Identification of a Glucose Distribution Model Connecting Glycemic Parameters Using Real-World Data.

Background: Time in range (TIR), time in tight range (TITR), and average glucose (AG) are used to adjust glycemic therapies in diabetes. However, TIR/TITR and AG can show a disconnect, which may create management difficulties. We aimed to understand the factors influencing the relationships between these glycemic markers. Materials and Methods: Real-world glucose data were collected from self-identified diabetes type 1 and type 2 diabetes (T1D and T2D) individuals using flash continuous glucose monitoring (FCGM). The effects of glycemic variability, assessed as glucose coefficient of variation (CV), on the relationship between AG and TIR/TITR were investigated together with the best-fit glucose distribution model that addresses these relationships. Results: Of 29,164 FCGM users (16,367 T1D, 11,061 T2D, and 1736 others), 38,259 glucose readings/individual were available. Comparing low and high CV tertiles, TIR at AG of 150 mg/dL varied from 80% ± 5.6% to 62% ± 6.8%, respectively (P < 0.001), while TITR at AG of 130 mg/dL varied from 65% ± 7.5% to 49% ± 7.0%, respectively (P < 0.001). In contrast, higher CV was associated with increased TIR and TITR at AG levels outside the upper limit of these ranges. Gamma distribution was superior to six other models at explaining AG and TIR/TITR interactions and demonstrated nonlinear interplay between these metrics. Conclusions: The gamma model accurately predicts interactions between CGM-derived glycemic metrics and reveals that glycemic variability can significantly influence the relationship between AG and TIR with opposing effects according to AG levels. Our findings potentially help with clinical diabetes management, particularly when AG and TIR appear mismatched.

Unsupervised damage assessment under varying ambient temperature based on an adjusted artificial neural network and new multivariate covariance-based distances

Temperature variability is one of the critical environmental conditions that causes confusing changes in structural properties and dynamic responses of bridges similar to damage. In this case, false alarms and mis-detection are among the major errors in health monitoring of such civil structures. High damage detectability is another significant challenge in bridge health monitoring. To deal with these issues, this article proposes an unsupervised damage assessment technique comprising two steps of data normalization and novelty detection. For the first step, an adjusted artificial neural network is considered to remove the effects of temperature variability from dynamic features (modal frequencies). This process is carried out by an auto-associative neural network by adjusting its hidden layer neurons through a new hyperparameter selection algorithm. Using normalized features obtained from the first step, this article proposes three multivariate covariance-based distances called linear dissimilarity analysis, multivariate Kullback–Leibler divergence, and multivariate Bregman distance to compute damage indices or novelty scores for damage assessment. The fundamental principles of these distances lie in three aspects: dividing the normalized features into segments, estimating the covariances of segmented feature sets, and incorporating the estimated covariances into the proposed distance measures. The major contributions of this article include proposing three non-parametric distance measures and developing an unsupervised data normalization framework via a new hyperparameter tuning algorithm for adjusting an artificial neural network. A concrete box-girder bridge is considered to verify the proposed approach, along with several comparative studies. Results show that the method presented here can mitigate severe temperature variability and increase damage detectability with superiority over some traditional and state-of-the-art damage assessment techniques.