Effects Of Testosterone Administration Research Articles

Effects of testosterone administration on acid soluble and insoluble glycogen in the levator ani muscle.

THERE is agreement in recent papers that testosterone is “glycopexic” and “glycostatic” with respect to several striated muscles (1–3). Early reports on the effects of testosterone on glycogen storage in striated muscles have been reviewed by Leonard (1). Bloom, Lewis, Schumpert, and Shen (4) have shown that cold tricholoroacetic acid (TCA) will consistently extract about 55% of the glycogen normally found in muscle following potassium hydroxide (KOH) digestion. These workers and others (5–9) have shown that tissue levels of TCA soluble and insoluble glycogen vary independently of each other under various physiological conditions. This has led to the concept that muscle glycogen may be comprised of two physiological entities. The present study was undertaken to determine the effects of testosterone propionate (TP) on TCA-soluble and insoluble glycogen, and to determine the relationship between the glycogen changes and the phenomenon of TP induced growth of the levator ani muscle in the rat.

Case of periarteritis nodosa treated by ACTH

SummaryAuthors report on a case of periarteritis nodosa. Diagnosis had been especially difficult on the basis of the poor symptomatology developed. Besides, symptoms of Basedow’s disease had been observed. The correlation of hyperthyroidism with periarteritis is not clear; no similar findings have been found in recent reviews on this matter.The benefit of the « ACTH » therapy was not entirely conclusive. The acute phase of the disease seemed to be stopped ; after 6 months observation, fever was reduced to a much lower level. However hyperthyroidism is not entirely corrected, until now. The palsy of the leg improved greatly. Urinary excretion of creatin was followed before and during ACTH therapy; the effects of testosterone administration were studied during periods with and without ACTH.Electromyographic studies of the palsied muscles before and during therapy showed quick functional improvment.

Effect of Testosterone Administration on the Beard Growth of Elderly Males

Effect of Testosterone Administration on the Beard Growth of Elderly Males