Effects Of Sodium Bicarbonate Ingestion Research Articles

Effect Of Sodium Bicarbonate Ingestion During Altitude Acclimatization On High-altitude, Short-duration, Cycling Performance

PURPOSE: Acute altitude exposure induces hyperventilation which, in turn, results in respiratory alkalosis. In an attempt to restore blood pH, the kidneys enhance the rate of bicarbonate excretion which may reduce the buffering capacity of the blood and, thus, the performance in exercises that generate large amounts of lactic acid. Consequently, bicarbonate supplementation during altitude acclimatization may restore the buffering capacity of the blood and enhance exercise performance more so than supplementation at sea level. The purpose of this study, therefore, was to evaluate the effect of sodium bicarbonate ingestion during an 8-hour altitude acclimatization period on subsequent short-duration, high-intensity cycling performance at an altitude of 10,000 ft. METHODS: Following 3 to 5 accommodation trials, four time-trials (TT) were conducted on ten trained males under the following conditions: normobaric/placebo (NPo); normobaric/sodium bicarbonate (NSB); hypobaric/placebo (HPo); and hypobaric/sodium bicarbonate (HSB). All trials were performed in a hypobaric altitude simulator. The TT included completing 360 revolutions as fast as possible on a cycle ergometer at a resistance equal to ≈ 5.5% body weight. RESULTS: The rate of urinary bicarbonate excretion was significantly (p =.005) higher during the hypobaric (1.264 ± 1.05 mg·min-1) versus the normobaric (.324 ±.37 mg·min-1) acclimatization period. Pre- to post-exercise increment in serum lactate concentration was larger (p =.03) by 4.08 ± 2.6 mmol·L-1 in HSB TT compared to HPo TT but the difference between the Normobaric TTs (2.58 ± 1.5 mmol·L-1) was not significant. No significant differences between placebo and SB ingestion trials under both hypobaric and normobaric conditions were found for pre- to post-exercise drop in serum bicarbonate concentration. Additionally, no significant difference was observed between placebo and SB ingestion trials for performance time under normobaric conditions (NPo: 305.0 ± 47.7 sec; NSB: 304.9 ± 44.8 sec) but a significant difference resulted under hypobaric conditions (HPo: 352.5 ± 55.1 sec; HSB: 341.2 ± 58.1 sec; p =.02). CONCLUSIONS: SB ingestion improved cycling performance under hypobaric conditions but not under normobaric conditions.

Effects of sodium bicarbonate ingestion on hyperventilation and recovery of blood pH after a short-term intense exercise

To determine the relationship between hyperventilation and recovery of blood pH during recovery from a heavy exercise, short-term intense exercise (STIE) tests were performed after human subjects ingested 0.3 g.kg(-1) body mass of either NaHCO3 (Alk) or CaCO3 (Pla). Ventilation (VE)-CO2 output (VCO2) slopes during recovery following STIE were significantly lower in Alk than in Pla, indicating that hyperventilation is attenuated under the alkalotic condition. However, this reduction of the slope was the result of unchanged VE and a small increase in VCO2. A significant correlation between VE and blood pH was found during recovery in both conditions. While there was no difference between the VE-pH slopes in the two conditions, VE at the same pH was higher in Alk than in Pla. Furthermore, the values of pH during recovery in both conditions increased toward the preexercise levels of each condition. Thus, although VE-VCO2 slope was decreased under the alkalotic condition, this could not be explained by the ventilatory depression attributed to increase in blood pH. We speculate that hyperventilation after the end of STIE is determined by the VE-pH relationship that was set before STIE or the intensity of the exercise performed.

Effects of Sodium Bicarbonate Ingestion on Performance and Perceptual Responses in a Laboratory-Simulated BMX Cycling Qualification Series

The objective of this study was to examine the effect of sodium bicarbonate (NaHCO3-) ingestion on performance and perceptual responses in a laboratory-simulated bicycle motocross (BMX) qualification series. Nine elite BMX riders volunteered to participate in this study. After familiarization, subjects undertook two trials involving repeated sprints (3 x Wingate tests [WTs] separated by 30 minutes of recovery; WT1, WT2, WT3). Ninety minutes before each trial, subjects ingested either NaHCO3- or placebo in a counterbalanced, randomly assigned, double-blind manner. Each trial was separated by 4 days. Performance variables of peak power, mean power, time to peak power, and fatigue index were calculated for each sprint. Ratings of perceived exertion were obtained after each sprint, and ratings of perceived readiness were obtained before each sprint. No significant differences were observed in performance variables between successive sprints or between trials. For the NaHCO3- trial, peak blood lactate during recovery was greater after WT2 (p < 0.05) and tended to be greater after WT3 (p = 0.07), and ratings of perceived exertion were not influenced. However, improved ratings of perceived readiness were observed before WT2 and WT3 (p < 0.05). In conclusion, NaHCO3- ingestion had no effect on performance and RPE during a series of three WT simulating a BMX qualification series, possibly because of the short duration of each effort and the long recovery time used between the three WTs. On the contrary, NaHCO3- ingestion improved perceived readiness before each WT.

Dose-related Effects of Sodium Bicarbonate Ingestion on Acid-base Balance During Exhausting Anaerobic Exercise

Dose-related Effects of Sodium Bicarbonate Ingestion on Acid-base Balance During Exhausting Anaerobic Exercise

Dose-related Effects of Sodium Bicarbonate Ingestion on Acid-base Balance During Exhausting Anaerobic Exercise

1166 Anaerobic exercise causes significant acid-base balance perturbations. It has been suggested that sodium bicarbonate (NaHCO3) may prevent a significant pH drop during anaerobic exercise resulting in performance enhancement. PURPOSE: To determine whether two intake levels of short-term NaHCO3 supplementation alters acid-base balance and performance during an acute bout of anaerobic exercise. METHODS: Twenty-four men (22 ± 1.77 yrs, 77.5 ± 7.8 kg, 1.79 ± 6.6 m, and a VO2max of 51.03 ± 7.53 ml/kg/min) participated in the present study. Subjects were randomly assigned to one of 3 groups (n = 8/group): control (C, sugar-free mixed fruit placebo), moderate NaHCO3 intake (MI, 0.3 gr/kg), and high NaHCO3 intake (HI, 0.5 gr/kg). Participants consumed either placebo or NaHCO3 for 6 days. pH, HCO3, PO2, PCO2, and lactate in arterialised blood as well as mean cycling power were determined prior to and immediately following a Wingate test (before and following the supplementation period). Data were analysed by ANOVA repeated measures. RESULTS: There was a significant increase (p<0.001) in post blood bicarbonate in MI and HI, and the elevation was incrementally related to the dosage. Exercise in C caused a reduction (p<0.05) of pH (7.42 ± 0.01 at rest vs. 7.15 ± 0.02 post-exercise) and PCO2 (mmHg) (39.8 ± 2.3 at rest vs. 34.3 ± 1.9 post-exercise) and an increase (p<0.001) of lactate (mM) (0.9 ± 0.1 at rest vs. 10.9 ± 2.0 post-exercise). Mean power (W/kg) increased (p<0.05) after supplementation in MI (7.36 ± 1.33 vs. 6.73 ± 0.95) and HI (7.72 ± 1.24 vs. 6.69 ± 1.38) with HI being more effective (p<0.05) than MI. After NaHCO3 ingestion, blood lactate (mM) was higher (p<0.05) during exercise in MI (12.3 ± 1.5 vs. 10.3 ± 2.1) and HI (12.4 ± 1.8 vs. 10.2 ± 1.1). pH was significantly (p<0.05) elevated post-exercise when NaHCO3 was ingested (7.305 ± 0.03 vs. 7.198 ± 0.02 in MI and 7.343 ± 0.02 vs. 7.2 ± 0.01 in HI). HCO3 decreased (p<0.05) with NaHCO3 ingestion post-exercise (29.8 ± 3.3 vs. 17.56 ± 2.5 in MI and 19.8 ± 3.2 vs. 32.3 ± 4.1 in HI). PO2 (mmHg) increased (p<0.05) with NaHCO3 consumption post-exercise (113.3 ± 7.7 vs. 93.2 ± 6.9 in MI and 116.7 ± 8.2 vs. 92.7 ± 7.5 in HI) with HI being more effective (P<0.05) than MI. PCO2 declined (p<0.05) with NaHCO3 supplementation post-exercise (42.8 ± 3.3 vs. 36.2 ± 2.9 in MI and 44.2 ± 5.3 vs. 34.8 ± 4.1 in HI) with HI being more effective (P<0.05) than MI. CONCLUSIONS: Short-term NaHCO3 ingestion may be beneficial for protecting against acid-base balance disturbances and improve performance during acute anaerobic exercise. However, it appears that this NaHCO3-effect on acid-base balance and performance is dose-related with higher intakes being more effective.

Effect of Sodium Bicarbonate Ingestion on High Intensity Exercise in Moderately Trained Women

Effect of Sodium Bicarbonate Ingestion on High Intensity Exercise in Moderately Trained Women

Effect of Sodium Bicarbonate Ingestion on High Intensity Exercise in Moderately Trained Women

The aim of this research was to determine whether sodium bicarbonate would improve total work and peak power during maximal cycling ergometer performance in 10 moderately trained women. Each subject undertook 3 max tests on a cycle ergometer: control (C), placebo (P), and bicarbonate (B) trials. For 5 subjects the order was C, B, and P; for the other 5 it was C, P, and B. During all tests, 75 μl of blood was drawn from each subject prior to ingestion of B or P, and again at 30-min intervals starting 90 min prior to the cycle test as well as immediately postexercise and at 1, 3, and 5 min post. Samples were analyzed for blood lactate, pH, blood bicarbonate, and base excess. Subjects rated their perceived exertion on the 20-point Borg scale. Blood bicarbonate was significantly higher prior to exercise in the B trial and was still significantly higher at the end of the test. There were no significant differences in max HR between trials. The amount of work completed in C and P was not different. Peak power was significantly improved in the B trial. Blood lactate in B was significantly higher at both postexercise and 1 min postexercise. Ratings of perceived exertion were significantly greater in B. The results indicate that women athletes can use bicarbonate buffering to improve work and power output during high intensity exercise of 60 sec duration. © 1997 National Strength & Conditioning Association.

The effects of sodium bicarbonate ingestion on exercise performance.

The effects of sodium bicarbonate ingestion on exercise performance.

The Effects of Sodium Bicarbonate Ingestion on Adenine Nucleotide Metabolism during Intermittent, High Intensity Exercise

The Effects of Sodium Bicarbonate Ingestion on Adenine Nucleotide Metabolism during Intermittent, High Intensity Exercise

Effect of sodium bicarbonate ingestion on exhaustive resistance exercise performance

Effect of sodium bicarbonate ingestion on exhaustive resistance exercise performance

Effects of sodium bicarbonate ingestion on anaerobic performance: a meta-analytic review.

Many researchers have investigated the effects of induced metabolic alkalosis, by ingestion of sodium bicarbonate, on anaerobic exercise performance. But the results have been inconsistent and often contradictory. The purpose of this review was to synthesize the varied findings using a meta-analytic approach. Twenty-nine investigations met our inclusion criteria. Results show that NaHCO3 ingestion clearly results in a more alkaline extracellular environment. The dosage, however, was only moderately related to the increase in pH and HCO3-. Overall, performance was enhanced but the range of effect sizes was large, -0.12 to 2.87. In studies that measured time to exhaustion, there was a mean 27 +/- 20% increase in duration. The treatment effect, however, was only weakly related to the degree of induced alkalosis. But in comparing the 19 studies that showed a positive treatment effect with the 16 that showed no effect, the former were associated with a greater increase in pH following ingestion of a somewhat larger dosage, and a greater decrease in pH with exercise.

The effects of alkaline treatment on short‐term maximal exercise

Abstract The effects of alkalosis on submaximal and maximal exercise performance of a relatively long duration have been investigated previously. The present study examined the effects of sodium bicarbonate ingestion on cycling performance of the 30 s Wingate Anaerobic Test using 13 male physical education students. Three hours prior to exercise, subjects ingested either table salt (control) or sodium bicarbonate (alkalosis) of equimolar dosage (10 and 13 g, respectively) in capsule form. Biopsies were taken from the m. vastus lateralis for determination of muscle fibre composition. Resting blood pH was 7.43±0.01 (mean±s.e.) for the alkaline condition versus 7.37 + 0.01 for the control condition (P < 0.01). Mean power output increased significantly (P<0.05) following alkaline treatment. Peak power output was not affected. No relationship was found between fibre type distribution and sensitivity to the alkaline treatment. The increased alkali reserve reduced mean post‐exercise acidosis by 0.05 pH units (P<...