This research was conducted determine the impact of spraying the increase regulator melatonin on the tolerance of some rootstock to salt stress. The results showed that Sour Orange root was significantly superior to the rest of the rootstocks, and recorded the highest increase in the rate (Height, diameter, quantity, and the area for leaves of plant), while the root Volkamer lemon was significantly the best by recording the highest rate of arid mass of the root system and plant life. Furthermore, irrigation with electrical connection water (1.7 ds.m-1) led to obtaining the highest values for vegetative plant girth growth characteristics (plant girth, stem diameter, number of leaves, leaf area, dry weight of the vegetative and root system and root length). Moreover, treatment with the growth regulator melatonin at a concentration of (100 mg.L-1) showed greatest percentage in the trait (plant height, diameter of the stem, number of leaves, size of the leaves, and dry weight of the vegetative both root system and root length). As well as, the binary and triple interactions between these study factors led to a clear significant superiority in the studied traits compared to the comparison treatment, as the triple interaction treatment (Sour Orange root + melatonin at 100 mg.l-1 as the concentration+ Irrigation of salinity water with concentration 1.7 ds.m-1) was the most significant treatment by giving the highest increase in the rate of vegetative characteristics. Finally, the treatment (rootstocks Volkamer lemon + melatonin at 100 mg.l-1 as the concentration + Irrigation of salinity water with concentration 1.7 dm. m-1) recorded the highest rate of length and weight of the root when it is dry system.