Effect Of Menstrual Cycle Research Articles

Relationships of total leukocyte, neutrophil and lymphocyte levels with the menstrual cycle in patients receiving fingolimod treatment.

Multiple sclerosis (MS) is a demyelinating, chronic, and progressive autoimmune disease of the central nervous system that causes the loss of axons and grey matter, and has a high prevalence in young female patients. Fingolimod is an oral treatment agent that acts by blocking the passage of the T lymphocytes responsible for the pathogenesis of MS from lymphoid tissue into the peripheral blood. We aimed to research the effects of menstrual cycles on leukocytes and lymphocyte levels in RRMS (relapsing-remitting MS) patients who received fingolimod treatment. This study was performed to determine the most suitable phase of the menstrual cycle in patients with RRMS for follow-up assessment of lymphopaenia levels after fingolimod treatment. The study population consisted of 41 RRMS patients receiving fingolimod therapy and 33 healthy women of reproductive age. Complete blood counts were performed in three different phases of the menstrual cycle, and the two groups were compared. Variability in the total leukocyte, lymphocyte, and neutrophil immune cell numbers between cycles was examined. The results indicated that total leukocyte, neutrophil, and lymphocyte levels were decreased in RRMS patients receiving fingolimod treatment, but these changes were not related to the phase of the menstrual cycle. In our study, leukocyte levels in healthy individuals were significantly lower in the proliferative phase than in other phases. The results indicated that lymphocyte monitoring in RRMS patients receiving fingolimod treatment can be performed at any stage of the menstrual cycle.

The effect of menstrual cycle and exercise intensity on psychological and physiological responses in healthy eumenorrheic women

Psychological responses such as affect, mood, motivation, anxiety are important considerations for exercise adherence. A large body of evidence indicates that exercise intensity is a controllable variable capable of increasing positive feelings. Investigations thus far, however, have not considered that the higher incidence of negative psychological responses in women could be due to physiological particularities of the menstrual cycle (MC). This project investigates the effect of MC phases and exercise intensity on psychophysiological responses in fourteen healthy, eumenorrheic and physically active women. Measuring psychophysiological responses before, during and after exercise, participants completed two exercise bouts of 15 min above and below the anaerobic threshold in the follicular phase (FP) and the luteal phase (LP) of the MC. Lower levels of depression and hostility and higher levels of vigor, affect and motivation were observed during exercise in the FP. Exercise at moderate intensity elicited more positive psychological responses compared to high-intensity exercise, highlighted by findings that affect and rating of perceived exertion were worse in the LP without changes in physiological responses. These findings suggest no effect of MC on physiological responses, but psychological responses are impaired in the LP, worsening particularly during exercise at high intensity.

Fronto-striatal changes along the menstrual cycle during working memory: Effect of sex hormones on activation and connectivity patterns

Frontal and striatal areas are the neuroanatomical basis for working memory (WM), as well as targets for sex steroids. However, up to date little is known regarding menstrual cycle (MC) effects on brain activation and connectivity patterns during verbal WM. To the best of our knowledge, this is the first longitudinal dataset to study dorsolateral prefrontal cortex, putamen and caudate activation and connectivity patterns during a verbal WM task along the natural MC. Thirty-nine naturally cycling healthy women were scanned three times locked to their MC (menses, pre-ovulatory and luteal phase). They performed an N-back task with two trial types, targets and lures, assessing (i) updating and (ii) inhibitory process respectively. Distinct patterns of fronto-striatal activation and connectivity changes were observed for each process. (i) For targets, we observed decreased connectivity between left striatum- and inferior frontal and parietal areas, the circuit underlying phonological WM, in response to elevated progesterone during the luteal phase. Simultaneously, we observed an alleviation of inhibition from fronto-striatal areas on areas related to higher cognitive effort and the salience network. (ii) For lures, negative inter-hemispheric connectivity between fronto-parietal areas during the pre-ovulatory phase, as well as increased connectivity between bilateral dorsolateral prefrontal cortex and posteromedial structures during the luteal phase. Overall, we corroborated a hormone mediated inter-hemispheric decoupling, enhanced frontal activity and disinhibition of the salience brain network and striatum during the luteal phase. In summary, we interpret these results in relation to a differential top-down regulation in higher hormone levels phases and hyperactive bottom-up network during the luteal phase, which could explain the vulnerability of this phase to MC associated disorders.

Effects of menstrual cycle and menopause on internal carotid artery shear-mediated dilation in women

The present study evaluated the effects of the menstrual cycle and menopause stages on the shear-mediated dilation of the ICA, a potential index of cerebrovascular endothelial function, in pre-, peri-, and postmenopausal women. Shear-mediated dilation of the ICA was increased from the low- to high-estradiol phases in naturally cycling premenopausal women and was reduced with advancing menopause stages. Furthermore, lower estradiol was associated with reduced shear-mediated dilation of the ICA, independent of age.

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Menstrual cycle effects on cardiovascular drift and maximal oxygen uptake during exercise heat stress.

Compared to other modulators of physiological strain associated with exercise heat stress, hyperthermia results in the greatest magnitude of cardiovascular (CV) drift and associated decrements in maximal oxygen uptake ([Formula: see text]). To determine if elevated core temperature in the luteal phase (LP) of the menstrual cycle results in greater CV drift and reductions in [Formula: see text] versus the follicular phase (FP). Seven women performed 15- and 45-min cycling bouts on separate occasions (60% [Formula: see text], 35°C) followed by a [Formula: see text] test during the FP and LP. CV drift was measured between 15 and 45min during the 45-min bout, and the 15-min bout was for measuring [Formula: see text] over the same time interval that CV drift occurred. Core temperature during LP was ~ 0.3°C higher than FP (P < 0.05), but changes from rest during exercise were similar between phases (all P > 0.05). Heart rate increased significantly over time but was not different between phases (P = 0.78). Stroke volume decreased more over time during LP compared to FP (P = 0.02), but the values were similar at the end of exercise between phases (both time points P > 0.05). [Formula: see text] decrements for FP (13%) and LP (16%) were also comparable (P = 0.97). The LP-FP difference in core temperature in this study was not sufficient to amplify CV strain and decrements in [Formula: see text]. Greater differences in core temperature may be required to independently modulate CV drift and accompanying decrements in [Formula: see text] during prolonged exercise heat stress.

Effects of sex and menstrual cycle on volume-regulatory responses to 24-h fluid restriction.

Reproductive hormones have significant nonreproductive physiological effects, including altering fluid regulation. Our purpose was to explore the impact of sex and menstrual cycle (MC) phase on volume-regulatory responses to 24-h fluid restriction (24-h FR). Participants (men: n = 12, 20 ± 2 yr; women: n = 10, 20 ± 1 yr) were assigned two randomized and counterbalanced fluid prescriptions [Euhy: euhydrated, urine specific gravity (USG) < 1.020; Dehy: 24-h FR, USG > 1.020]. Men completed both (MEuhy, MDehy), while women completed both in the late-follicular (days 10-13; FDehy, FEuhy) and midluteal (days 18-22; LDehy, LEuhy) phases. We measured body mass, plasma and urine osmolality (Posm, Uosm), urine specific gravity (USG), urine color (Ucol), and serum copeptin; 24-h FR yielded mild dehydration without influence of sex or MC (P > 0.05). Copeptin increased in men following Dehy (pre: 8.2 ± 5.2, post: 15.8 ± 12.6, P = 0.04) but not in women (FDehy pre: 4.3 ± 1.6, post: 10.5 ± 6.9, P = 0.06; LDehy pre: 5.6 ± 3.5, post: 10.4 ± 6.2, P = 0.16). In FDehy, Posm increased following FR (pre: 288 ± 2, post: 292 ± 1, P = 0.03) but not in men (pre: 292 ± 3, post: 293 ± 2, P = 0.46). No MC differences were observed between body mass loss, Posm, Uosm, USG, and copeptin (P > 0.05). These results suggest that volume-regulatory responses to 24-h FR were present in men but not in women, without apparent effects of the menstrual cycle.

Neuromuscular Control of Ankle-stabilizing Muscles-specific Effects of Sex and Menstrual Cycle.

The purpose of this study was to examine the differences in neuromuscular control and mechanical properties of the ankle-stabilizing muscles between men and women, and during different phases of menstrual cycle in women. Fifteen women with regular menstrual cycles and 17 male counterparts were included in this study. Electromyographic signals were recorded from the peroneus longus (PL) and tibialis anterior (TA) muscles while performing three balance tasks. Muscle tone, stiffness, and elasticity of muscles were measured using a MyotonPRO in the resting position. Outcomes were measured twice (ovulation and early follicular phases) for women, while measurements were acquired only once for men. Significantly higher tibialis anterior-peroneus longus co-contraction (TA/PL ratio) was observed in all balance tasks in women than in men (p< 0.05); however, significant differences between phases of the menstrual cycle were noted only in the 2 most difficult tasks (p< 0.05). A similar pattern was observed in the postural sway. These results highlight the importance of sex-specific hormonal effects on neuromuscular control and mechanical properties, and as well as the differences during phases of the menstrual cycle. These insights assume significance in the context of developing neuromuscular strategies for the purpose of preventing lower extremity injuries during sports activities.

Counterpoint: Investigators should not control for menstrual cycle phase when performing studies of vascular control that include women.

Observed sex differences in the epidemiology of cardiovascular disease incidence and the efficacy of clinical intervention strategies, coupled with recent mandates from the National Institutes of Health (NIH), and its international counterparts to consider sex as a biological variable in all preclinical and clinical work (15), have led to increased enrollment of women in human physiology studies of vascular function with the goal of improving external validity and clinical applicability of the findings. However, standard practice in these studies is to test women during the early follicular phase (~days 1-5) of the menstrual cycle, during which estrogen and progesterone concentrations are lowest, and either exclude or limit testing of women who use hormonal contraceptives to the placebo phase. This approach seeks to control for, or limit, differences in circulating hormone concentrations between men and women and is based on the dogmatic theory that cyclic changes in estrogen and progesterone concentrations lead to greater variability in study outcomes and uninterpretable datasets. Contrary to this common approach, we propose that limiting testing of women to this single phase 1) decreases external validity of the findings, 2) obfuscates potential physiological differences contributable to differences in sex hormone concentrations between men and women, and 3) is, in many instances, contradicted by literature that demonstrates limited or no variability in vascular measurements across the menstrual cycle.

Effect of menstrual cycle on resting metabolism: A systematic review and meta-analysis.

BackgroundThe need to control for the potential influence of menstrual cycle phase on resting metabolism (RMR) places a burden on research participants who must self-report onset of menstruation and researchers who must schedule metabolic testing accordingly.PurposeTo systematically review and analyze existing research to determine the effect of menstrual cycle on RMR.MethodsWe searched PubMed, CINAHL, MEDLINE, SPORTDiscus, and Scopus databases using the search terms “menstrual cycle and metabolic rate” and “menstrual cycle and energy expenditure.” Eligibility criteria were English language, single-group repeated measures design, and RMR as either a primary or secondary outcome. Risk of bias was assessed based on study sample, measurement, and control of confounders. Differences between the follicular and luteal phases of the menstrual cycle were analyzed using the standardized mean difference in effect size.ResultsThirty English-language studies published between 1930 and December 2019 were included in the systematic review, and 26 studies involving 318 women were included in the meta-analysis. Overall, there was a small but significant effect favoring increased RMR in the luteal phase (ES = 0.33; 95% CI = 0.17, 0.49, p < 0.001).DiscussionLimitations include risk of bias regarding measurement of both menstrual cycle and RMR. Sample sizes were small and studies did not report control of potential confounders. Sub-group analysis demonstrated that in more recent studies published since 2000, the effect of menstrual phase was reduced and not statistically significant (ES = 0.23; 95% CI = -0.00, 0.47; p = 0.055). Until larger and better designed studies are available, based on our current findings, researchers should be aware of the potential confounding influence of the menstrual cycle and control for it by testing consistently in one phase of the cycle when measuring RMR in pre-menopausal women.

Effect of the Menstrual Cycle When Estimating 1 Repetition Maximum From the Load-Velocity Relationship During the Bench Press Exercise.

García-Pinillos, F, Lago-Fuentes, C, Bujalance-Moreno, P, and Pérez-Castilla, A. Effect of the menstrual cycle when estimating 1 repetition maximum from the load-velocity relationship during the bench press exercise. J Strength Cond Res 36(3): e55-e58, 2022-This study aimed to examine the effect of the ovulatory menstrual cycle (MC) when estimating the 1 repetition maximum (1RM) from the individual load-velocity relationship during the bench press (BP) exercise. Nine resistance-trained eumenorrheic women (age: 28.7 ± 3.6 years) were tested in 3 different phases across the MC: menstrual or early follicular phase (i.e., testing between days 1-3), follicular or late follicular phase (i.e., testing between days 7-10), and luteal or mid-luteal phase (i.e., testing between days 19-21). Each testing trial consisted of an incremental loading protocol against 4 loading conditions (≈50-70-80-90% 1RM) in the concentric-only BP exercise. A smartphone application (MyLift) was used to collect the mean velocity (MV) of all repetitions. The 1RM was estimated from the individual load-velocity relationship by applying a linear regression model as the load associated with an MV of 0.17 m·s-1. In addition, the MV obtained at each %1RM (i.e., from 20% 1RM to 80% 1RM in 20% increments), the load-velocity slope (i.e., the decrease in MV per each 1% of increment in the %1RM), and the y-intercept (i.e., the estimate of MV at 0% 1RM) were computed from the individual load-velocity relationships. No significant differences were observed between the 3 phases of the MC for any of the measured load-velocity relationship parameters (corrected p-value ≥0.495; effect size ≤0.24). The results suggest that the estimation of the BP 1RM from the load-velocity relationship seems not to vary over the 3 different phases of the MC (i.e., menstrual, follicular, and luteal phases).

Menstrual Cycle Effects on Exercise-Induced Fatigability.

Estrogen and progesterone have distinct concentrations across the menstrual cycle, each one promoting several physiological alterations other than preparing the uterus for pregnancy. Whether these physiological alterations can influence motor output during a fatiguing contraction is the goal of this review, with an emphasis on the obtained effect sizes. Studies on this topic frequently attempt to report if there is a statistically significant difference in fatigability between the follicular and luteal phases of the menstrual cycle. Although the significant difference (the P-value) can inform the probability of the event, it does not indicate the magnitude of it. We also investigated whether the type of task performed (e.g., isometric vs. dynamic) can further influence the magnitude by which exercise-induced fatigue changes with fluctuations in the concentration of ovarian hormones. We retrieved experimental studies in eumenorrheic women published between 1975 and 2019. The initial search yielded 921 studies, and after manual refinement, 46 experimental studies that reported metrics of motor output in both the follicular and luteal phases of the menstrual cycle were included. From these retrieved studies, 15 showed a statistical difference between the luteal and follicular phases (seven showing less fatigability during the luteal phase and eight during the follicular phase). The effect size was not consistent across studies and with a large range (-6.77; 1.61, favoring the luteal and follicular phase, respectively). The inconsistencies across studies may be a consequence of the differences in the limb used during the fatiguing contraction (upper vs. lower extremity), the type of contraction (isometric vs. dynamic), the muscle mass engaged (single limb vs. full body), and the techniques used to define the menstrual cycle phase (e.g., serum concentration vs. reported day of menses). Further studies are required to determine the effects of a regular menstrual cycle phase on the exercise-induced fatigability.

1090 Self-Reported Sleep Quality is a Robust Predictor of Depression in Women With Irregular Menstrual Cycles

Abstract Introduction Menstrual cycle regularity is an important marker of women’s health. Abnormalities are associated with serious health complaints, e.g., infertility, cardiovascular, and metabolic disorders. Cycle irregularity is also linked to depression, anxiety and poor quality sleep. In fact, poor sleep and circadian misalignment may precede menstrual irregularity for some. This study describes sleep and affective characteristics of women with menstrual cycle irregularity compared to regularly cycling women and examined the individual contributions of sleep and menstrual regularity to affective symptoms. Methods N=314 (Mage=20.95, SD=2.35) women provided reports of menstrual health characteristics (frequency, duration, related symptoms), sleep over the past month (Pittsburgh Sleep Quality Index; PSQI) and on the previous night, as well as mood (Center for Epidemiologic Studies Depression Scale) and anxiety (State Trait Anxiety Inventory) symptoms. Results Among the 20.4% (n=64) of women who endorsed “always irregular” periods, mean cycle length (m=31.33 days, sd=8.5) was significantly greater than among women more regular periods (m= 27.93, sd=3.83, t(55.37)=-2.78, p=.007). This subgroup also reported higher PSQI scores (t(181)=-2.56, p=.011), longer SOL (t(282)=-3.00, p=.003), poorer sleep quality overall (t(299)=-2.35, p=.02), and poorer sleep quality on the previous night (t(300)=2.70, p=.007). Irregular cyclers reported significantly more depressive (t(284)=-2.18, p=.03) but not anxiety symptoms. When sleep and menstrual irregularity were entered into a hierarchical linear regression to examine their relative influence on depressive symptoms (F[2,174]=13.15, p&amp;lt;.001, R2=.13), sleep remained the only significant predictor (b= 1.13, p &amp;lt;.001) and menstrual cycle effects were no longer significant. Conclusion In line with previous studies, cycle irregularity was associated with poorer sleep quality and depressive symptoms. Sleep quality was found to be a more robust predictor of depression than menstrual cycle irregularity, suggesting that sleep may underlie the affective disturbances in women with more irregular menstrual cycles. Support n/a

T141. EFFECTS OF MENSTRUAL CYCLE ON RESTING STATE FUNCTIONAL CONNECTIVITY IN SCHIZOPHRENIA: A FUNCTIONAL MRI STUDY

BackgroundThe menstrual cycle is a favorable model for examining the influence of ovarian hormones on cognition, emotion and brain functions. Ovarian hormones have substantial effects on task-related brain activity, but their impacts on functional connectivity at rest have been investigated by a few studies conducted with healthy individuals and these pre-existing findings are inconsistent. As for schizophrenia, different influences of ovarian hormones were reported. For instance, the estrogen hypothesis of schizophrenia has suggested that estrogen plays a neuroprotective role in the pathophysiology of this disorder. The present study investigates resting state functional connectivity (RS-FC) alterations related to menstrual cycle phase and/or hormone levels in patients with schizophrenia and healthy controls and aims to contribute to the understanding of the effects of ovarian hormones on the pathogenesis of schizophrenia and brain functions.MethodsThe study was conducted with 13 women with schizophrenia (the mean of age: 32 ± 7.67) and 13 healthy women (the mean of age: 30.08 ± 7.27). Resting state functional Magnetic Resonance Imaging (fMRI) scanning, as well as hormonal and clinical assessments, were applied to each participant twice, during two menstrual cycle phases: early follicular (Days 2–6; low estrogen/progesterone) and mid-luteal (Days 20–22; high estrogen/progesterone). The serum hormone levels of estradiol, progesterone, prolactin (only in the patients), follicle-stimulating and luteinizing were assessed. The clinical assessment interviews included the Brief Psychiatric Rating Scales, the Clinical Global Impression (only for the patients), the Global Assessment of Functioning and the Calgary Depression Rating Scale for Schizophrenia (for both groups).ResultsOur findings revealed that no cycle phase-related alterations existed in RS-FC in both groups. However, specific correlations between each hormone and RS-FC were found in both cycle phases for two groups. In the patients, estrogen was positively correlated with the auditory network (AN) connectivity in the left amygdala at the early follicular phase. In the controls, the positive correlations to progesterone were found in the precuneus for the connectivity of the posterior default mode network (DMN) and the left-frontoparietal network (FPN) during the early follicular phase. Also, progesterone was negatively correlated with the executive control network (ECN) connectivity in the right superior frontal gyrus at the mid-luteal phase in the controls. Furthermore, the patients had lower progesterone levels during the mid-luteal phase compared to the controls (p<0.05). The severity of the psychotic symptoms of the patients didn’t change between the cycle phases.DiscussionTo our knowledge, this is the first study to examine the influence of the menstrual cycle on the brain’s RS-FC in schizophrenia. Our results indicated that the effects of the menstrual cycle on RS-FC were more prominent in the controls rather than the patients with schizophrenia; and that the findings for the patient group may be associated with the additional mechanisms responsible from schizophrenia. This might imply that differentiating the menstrual cycle effects is difficult in a complex disorder such as schizophrenia. The results obtained from the controls are consistent with the previous findings indicating that the menstrual cycle effects might be associated with the connectivity of the DMN and cognition-related networks. Moreover, our results suggested that estrogen might have a modulating effect on the intrinsic functional connectivity changes in the patients, while progesterone, might mediate to that in the controls.

Effects of menstrual cycle on nausea and vomiting after general anesthesia.

To investigate the impact of menstrual cycle on patients undergoing gynecological endoscopic surgery. 220 patients scheduled for gynecological endoscopic surgery under general anesthesia were selected. The patients were divided into three groups based on 3 phases of menstrual cycle which are the follicular phase (Group F), ovulatory phase (Group O) or luteal phase (Group L). It is based on their duration of menstruation and the last day of menstrual bleeding from the date of surgery. Primary outcomes were the incidences of early and late postoperative nausea and vomiting (PONV) in the three patient groups. Preoperative venous blood was taken to determine the estrogen and progesterone levels of the patients. A total of 207 patients were enrolled. The incidence of early PONV was highest in group O (22.22% vs 43.33% vs 17.86%, P < 0.01). Multivariate logistic regression showed that menstrual cycle (P < 0.01) and sufentanil dosage (P < 0.05) were independent risk factors for early PONV, menstrual cycle (P = 0.03) and intraoperative hypotension (P = 0.03) were independent risk factors for late PONV. After the propensity matching, the incidences of early and late PONV in group O were both higher than that in other two groups (19.23% vs 44.68% vs 16.90%, P < 0.01; 53.80% vs 72.34% vs 45.07%, P = 0.01). The incidence of PONV after gynecological endoscopic surgery was different in patients with different menstrual cycles, with the highest incidence in ovulation.

Effect of Menstrual Cycle on Sport Performance in Archers

Effect of Menstrual Cycle on Sport Performance in Archers

The Impact of Menstrual Periods on Performance of Female Workers

In line with legislative future vision, number of female employees has been increasing in Saudi Arabia. Female workers experience challenges that male counterparts may not face such as monthly physiological and hormonal changes. Consequentially, raising the question; would this affect female work performance? Hence, this study aimed to survey menstrual cycle effects on performance, physical condition and habits of workers for Princess Nourah bint Abdulrahman University (PNU). Target subjects included variable departments and different ages to ensure representatives sample as much possible. Next, data was collected using self-reported surveys approaching convince sampling method. Then, data were coded to SPSS and analysed in forms of descriptive frequencies and percentages with P value less than 0.05 deemed to be significant. 395 useful questioners were analysed. 95% of workers thought that their physical activity decreases during period. 67% of them usually suffer from back pain and 33% reported abdominal pain. Almost halve (47%) feel depressed through their period. More than halve (60%) believed their focus and concentration level is not decreased during menstruation and 73% have never needed to request vacation due to menstrual pain neither permission to leave work 36%. Also, (73%) do not require assistance from colleagues to perform office duties. 50% will take Panadol as analgesic for period pain. As well, 10% will use water bags in workplace to relive menstruation pain, while (66%) will use herbs to manage period pain. Finally, the study concluded that menstruation do affect PNU workers Physical condition and habits. Yet, they believe their cognitive and focus level is not affected.

The effect of menstrual cycle on maximal breath-hold time

This study investigated the effect of menstrual cycle phase on breath-hold time (BHT). Twelve healthy females, aged 18–30 yrs, with regular menstrual cycles, without breath-hold (BH) experience, performed a BH protocol which included eight repeated maximal efforts with face immersion in cool water separated by 2-min intervals in two different phases of menstrual cycle; early follicular (EF) phase and midluteal (ML) phase. Respiratory, cardiovascular and hematological responses were studied before, during and after BH efforts. Maximal BHT was significantly higher during ML (115.59 ± 13.95 s) compared to EF (106.10 ± 12.42 s) phase of the menstrual cycle. Metabolic rate and build-up of CO2 were higher (p < 0.001) in EF compared to ML phase. In conclusion, the greater BHT observed at the ML phase of the menstrual cycle may be the result of elevated levels of estrogen and progesterone during midluteal phase affecting both ventilatory response and metabolic rate.

Defending the Queen’s Pride: Effect of the menstrual cycle phase on conspicuous consumption

Women experience both physical and psychological changes during different phases of the menstrual cycle (MC), which can affect their decision making. The present study aims to investigate the impact of the MC on women’s preferences for conspicuous consumption. In three studies, women in the low-fertility phase were found to be more inclined toward conspicuous consumption, with the MC effect on conspicuous consumption being mediated by the extent of pride. We assumed that women in the low-fertility phase would feel less proud due to an evolutionary drive and that they would consume conspicuous products as a means of compensation. Meanwhile, women who were only children did not manifest such behavior. We infer that women from one-child families may have a greater sense of security and confidence, which buffers the mediating effect. This research contributes to both evolutionary psychology and marketing research and provides new insights for future studies.

The Impact of Menstrual Periods on Performance of Female Workers

In line with legislative future vision, number of female employees has been increasing in Saudi Arabia. Female workers experience challenges that male counterparts may not face such as monthly physiological and hormonal changes. Consequentially, raising the question; would this affect female work performance? Hence, this study aimed to survey menstrual cycle effects on performance, physical condition and habits of workers for Princess Nourah bint Abdulrahman University (PNU). Target subjects included variable departments and different ages to ensure representatives sample as much possible. Next, data was collected using self-reported surveys approaching convince sampling method. Then, data were coded to SPSS and analysed in forms of descriptive frequencies and percentages with P value less than 0.05 deemed to be significant. 395 useful questioners were analysed. 95% of workers thought that their physical activity decreases during period. 67% of them usually suffer from back pain and 33% reported abdominal pain. Almost halve (47%) feel depressed through their period. More than halve (60%) believed their focus and concentration level is not decreased during menstruation and 73% have never needed to request vacation due to menstrual pain neither permission to leave work 36%. Also, (73%) do not require assistance from colleagues to perform office duties. 50% will take Panadol as analgesic for period pain. As well, 10% will use water bags in workplace to relive menstruation pain, while (66%) will use herbs to manage period pain. Finally, the study concluded that menstruation do affect PNU workers Physical condition and habits. Yet, they believe their cognitive and focus level is not affected.