Effects Of Fructooligosaccharides Research Articles

Effect of fructooligosaccharide on nutritional parameters and mineral bioavailability in rats

AbstractThe effect of fructooligosaccharide on protein digestibility and mineral absorption was studied in rats fed diets containing 5 g kg−1 fructooligosaccharide, 5 g kg−1 cellulose/fructooligosaccharide (1:1) or 5 g kg−1 cellulose as a source of dietary fibre. Addition of cellulose/fructooligosaccharide or fructooligosaccharide to the diet did not significantly modify the daily food intake and food efficiency. However, the fructooligosaccharide‐fed group showed a significant decrease in body weight gain compared with cellulose‐fed groups. Faecal excretion was significantly lower when there was fructooligosaccharide intake, despite there being no significant differences in cellulose‐fed groups. Intake of fructooligosaccharide produced an increase in caecal content and an enlargement of the caecal wall. This trophic effect could be attributed to short‐chain fatty acids produced from the anaerobic fermentation of fructooligosaccharide by intestinal bacteria. Cellulose/fructooligosaccharide enhanced the apparent absorption and apparent retention of Ca, Mg, Zn and Fe. Fructooligosaccharide‐fed rats experienced an increase in apparent absorption and apparent retention of Mg compared with cellulose‐fed rats. Fructooligosaccharide intake at the lowest dose was enough to provide a desirable effect on mineral bioavailability in rats without any modification of nutritional parameters.© 2002 Society of Chemical Industry

Effects of fructooligosaccharide on bowel function and indicators of nutritional status in constipated elderly men

Five subjects completed the study consisting of a 30-d low fiber control period and another 30-d experimental period in which 10 g of FO was supplemented to a 3-d cycle menus. Status of large bowel function was monitored daily. Feces were completely collected on last 5 d of each period to determine the fecal characteristics and fecal short-chain fatty acid (SCFA) contents. Nutrient intake, body weight, arm anthropometric parameters, serum albumin, total protein, triglyceride, cholesterol, and electrolytes were measured as indices of nutritional status. Incorporation of FO significantly increased the defecation frequency, daily stool weight, weight per stool and decreased the use of enema. Concentrations of fecal acetate, propionate, i-butyrate, n-butyrate, i-valerate and n-valerate increased by 3–18 fold in the experimental period. Nutrient intake and anthropometric indices remained constant throughout the study. Serum concentrations of Na and K were decreased and concentrations of Ca and P were increased in the experimental period. Other blood biochemical parameters were not affected by the treatment. Therefore, we conclude that supplementation of FO was able to alleviate constipation, increase stool weight and fecal SCFA concentrations without affecting plasma lipid concentrations in the normolipidemic, constipated elderly men.

Effect of fructooligosaccharides (FOS) andlactulose on gas production: An in vivo and in vitro study

Effect of fructooligosaccharides (FOS) andlactulose on gas production: An in vivo and in vitro study

Effects of fructo-oligosaccharides on milk-yield and milk-components of dairy cows

Effects of fructo-oligosaccharides on milk-yield and milk-components of dairy cows

Effects of fructo-oligosaccharides on blood glucose and serum lipids in diabetic subjects

Daily intake of 8.0 g per day of fructo-oligosaccharides for fourteen days significantly reduced mean fasting blood glucose levels by 15 mg/dl, mean serum total cholesterol levels by 19 mg/dl and LDL-cholesterol levels by 17 mg/dl in diabetic subjects (n=18), while the control diabetic subjects (n=10) who were given 5.0 g per day of sucrose showed no significant changes. The levels of serum HDL-cholesterol, triglycerides or free fatty acids were not significantly affected either by fructo-oligosaccharides or sucrose. These results indicate that the daily intake of fructo-oligosaccharides ameliorates the derangements of carbohydrate and lipid metabolism in diabetic subjects.